Home Metabolism PPAR agonist Rosiglitazone HCl For research use only.

Rosiglitazone HCl

Synonyms: BRL-49653 HCl

Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.

Rosiglitazone HCl Chemical Structure

Rosiglitazone HCl Chemical Structure

CAS: 302543-62-0

Selleck's Rosiglitazone HCl has been cited by 19 Publications

3 Customer Reviews

Purity & Quality Control

Batch: Purity: 99.75%
99.75

Other PPAR Products

Related compound libraries

Choose Selective PPAR Inhibitors

Biological Activity

Description Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
Targets
PPAR [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02737709 Terminated Non-small Cell Lung Cancer Sun Yat-sen University March 2016 Phase 2
NCT01402076 Completed Healthy Volunteers Vanda Pharmaceuticals August 2011 Phase 1
NCT01415128 Completed Erectile Dysfunction VIVUS LLC April 2010 Phase 1
NCT01100619 Completed Papillary Thyroid Cancer|Follicular Thyroid Cancer|Huerthle Cell Thyroid Cancer|Renal Cell Carcinoma Exelixis April 2010 Phase 1
NCT01376063 Completed Healthy Adult Subjects FibroGen March 2010 Phase 1

Chemical lnformation & Solubility

Molecular Weight 393.89 Formula

C18H19N3O3S.HCl
CAS No. 302543-62-0 SDF Download Rosiglitazone HCl SDF
Smiles CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 79 mg/mL ( (200.56 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 79 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Rosiglitazone HCl | Rosiglitazone HCl ic50 | Rosiglitazone HCl price | Rosiglitazone HCl cost | Rosiglitazone HCl solubility dmso | Rosiglitazone HCl purchase | Rosiglitazone HCl manufacturer | Rosiglitazone HCl research buy | Rosiglitazone HCl order | Rosiglitazone HCl mouse | Rosiglitazone HCl chemical structure | Rosiglitazone HCl mw | Rosiglitazone HCl molecular weight | Rosiglitazone HCl datasheet | Rosiglitazone HCl supplier | Rosiglitazone HCl in vitro | Rosiglitazone HCl cell line | Rosiglitazone HCl concentration | Rosiglitazone HCl nmr