Home Metabolism P450 (e.g. CYP17) inhibitor - Adenosine Receptor inhibitor Ticlopidine For research use only.

Ticlopidine

Synonyms: Yuclid, Ticlopidinum, Ticlopidina,PCR 5332

Ticlopidine (Yuclid, Ticlopidinum, Ticlopidina,PCR 5332) is an orally active inhibitor of platelet aggregation induced by adenosine diphosphate (ADP). Ticlopidine is also an inhibitor of CYP2B6 with Ki of 0.2 μM.

Ticlopidine Chemical Structure

Ticlopidine Chemical Structure

CAS: 55142-85-3

Purity & Quality Control

Batch: S072101 Purity: 99.40%
99.40

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Biological Activity

Description Ticlopidine (Yuclid, Ticlopidinum, Ticlopidina,PCR 5332) is an orally active inhibitor of platelet aggregation induced by adenosine diphosphate (ADP). Ticlopidine is also an inhibitor of CYP2B6 with Ki of 0.2 μM.
Targets
ADP [1] CYP2B6 [2]
(Cell-free assay)
0.2 μM(Ki)

Chemical lnformation & Solubility

Molecular Weight 263.79 Formula

C14H14ClNS
CAS No. 55142-85-3 SDF --
Density 1.273 g/mL
Smiles C1CN(CC2=C1SC=C2)CC3=CC=CC=C3Cl
Storage (From the date of receipt) 2 years 4°C liquid

In vitro
Batch:

DMSO : 20 mg/mL ( (75.81 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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