Vitamin K1

Synonyms: Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione

Vitamin K1 (Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione), made by plants, is a major type of dietary vitamin K, which is well-known for its role in blood clotting. Vitamin K1 is directly involved in photosynthesis.

Vitamin K1 Chemical Structure

Vitamin K1 Chemical Structure

CAS: 84-80-0

Purity & Quality Control

Batch: Purity: 99.46%
99.46

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Biological Activity

Description Vitamin K1 (Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione), made by plants, is a major type of dietary vitamin K, which is well-known for its role in blood clotting. Vitamin K1 is directly involved in photosynthesis.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05505552 Recruiting Osteo Arthritis Knee Tufts University|University of North Carolina Chapel Hill|Tufts Medical Center September 20 2023 Not Applicable
NCT05610137 Completed Dietary Intake Vanessa Corrales Agudelo|Vidarium Nutrition Health and Wellness Research Center October 18 2022 --
NCT05060809 Completed Vascular Calcification Assiut University January 1 2018 Phase 4
NCT01763307 Unknown status Rash Due to Epidermal Growth Factor Receptor Inhibitors Hadassah Medical Organization January 2013 Phase 2
NCT02515214 Recruiting Bariatric Surgery Candidate|Pregnancy Universitaire Ziekenhuizen KU Leuven July 2012 --

Chemical lnformation & Solubility

Molecular Weight 450.70 Formula

C31H46O2

CAS No. 84-80-0 SDF --
Density 0.984 g/mL at 25 °C
Smiles CC1=C(C(=O)C2=CC=CC=C2C1=O)CC=C(C)CCCC(C)CCCC(C)CCCC(C)C
Storage (From the date of receipt) 2 years -80°C liquid

In vitro
Batch:

DMSO : 90 mg/mL ( (199.68 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 90 mg/mL

Ethanol : 90 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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