Home Neuronal Signaling Adrenergic Receptor agonist - Autophagy activator Clonidine HCl For research use only.

Clonidine HCl

Synonyms: Kapvay

Clonidine HCl(Kapvay) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.

Clonidine HCl Chemical Structure

Clonidine HCl Chemical Structure

CAS: 4205-91-8

Selleck's Clonidine HCl has been cited by 1 publication

Purity & Quality Control

Batch: S245801 DMSO] 53 mg/mL] false] Water] 53 mg/mL] false] Ethanol] 53 mg/mL] false Purity: 99.97%
99.97

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Biological Activity

Description Clonidine HCl(Kapvay) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.
Targets
α2-adrenergic receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05943613 Not yet recruiting Postoperative Pain Assiut University December 1 2023 Phase 1
NCT05091242 Recruiting Emergence Delirium Rigshospitalet Denmark October 25 2021 Phase 2|Phase 3
NCT05029401 Recruiting Opiate Withdrawal Syndrome DemeRx IB Inc.|MAC Clinical Research|ERT: Clinical Trial Technology Solutions|Hammersmith Medicines Research April 1 2021 Phase 1|Phase 2
NCT03537612 Terminated Scoliosis Dr. Jean A. Ouellet MD FRCSC|Shriners Hospitals for Children June 22 2018 Phase 3
NCT04928651 Completed Intensive Care Neonatal|Analgesia|Hypnotics and Sedatives Region Skane|Lund University|Karolinska Institutet|Helsinki University Central Hospital|Great Ormond Street Hospital for Children NHS Foundation Trust|Örebro University Sweden|The Swedish Research Council|University of Tartu|University of Colorado Denver April 6 2018 --

Chemical lnformation & Solubility

Molecular Weight 266.5 Formula

C9H9Cl2N3.HCl
CAS No. 4205-91-8 SDF Download Clonidine HCl SDF
Smiles C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 53 mg/mL ( (198.87 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 53 mg/mL

Ethanol : 53 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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