Home Neuronal Signaling P2 Receptor antagonist - Dyes chemical Brilliant Blue G For research use only.

Brilliant Blue G

Synonyms: BBG

Brilliant Blue G (BBG) is a dye which is commonly used in laboratories to stain or quantify proteins.Brilliant Blue G is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively.

Brilliant Blue G Chemical Structure

Brilliant Blue G Chemical Structure

CAS: 6104-58-1

Selleck's Brilliant Blue G has been cited by 2 publications

Purity & Quality Control

Batch: Purity: 99.8%
99.8

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Biological Activity

Description Brilliant Blue G (BBG) is a dye which is commonly used in laboratories to stain or quantify proteins.Brilliant Blue G is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively.
Targets
rat P2X7 [1]
(Cell-free assay)		 human P2X7 [1]
(Cell-free assay)
10.1 nM 265 nM

Chemical lnformation & Solubility

Molecular Weight 854.02 Formula
C47H48N3NaO7S2
CAS No. 6104-58-1 SDF --
Smiles [Na+].CCOC1=CC=C(NC2=CC=C(C=C2)\C(C3=CC=C(C=C3C)N(CC)CC4=CC=CC(=C4)[S]([O-])(=O)=O)=C/5C=CC(/C=C5C)=[N+](/CC)CC6=CC=CC(=C6)[S]([O-])(=O)=O)C=C1
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (117.09 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 4 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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