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Sasapyrine

Name: Sasapyrine
Brand: Selleck Chemicals
SKU: S4188

Synonyms: NSC-49171,Salsalate

Catalog No.S4188 Purity: 99.2%

Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.

Sasapyrine Chemical Structure

CAS: 552-94-3

Purity & Quality Control

Batch: S418801 DMSO] 52 mg/mL] false] Ethanol] 52 mg/mL] false] Water] Insoluble] false Purity: 99.2%

99.2

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Biological Activity

Description	Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT03482440	Recruiting	Preeclampsia	University of Iowa\|Penn State University	August 26 2018	Early Phase 1
NCT03277573	Unknown status	Alzheimer Disease	Adam Boxer\|University of California San Francisco	July 21 2017	Phase 1
NCT01977417	Terminated	Prediabetes\|Obese	Gary L. Pierce\|University of Iowa	November 2012	Phase 2
NCT01489319	Terminated	Polycystic Ovary Syndrome	Indiana University	February 2012	Phase 1
NCT01182727	Completed	Schizophrenia\|Insulin Resistance	University of Maryland Baltimore\|US Department of Veterans Affairs	August 2010	Not Applicable

References

Chemical lnformation & Solubility

Molecular Weight	258.23	Formula	C₁₄H₁₀O₅
CAS No.	552-94-3	SDF	Download Sasapyrine SDF
Smiles	C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 52 mg/mL ( (201.37 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 52 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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