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Tetrahydrozoline HCl

Name: Tetrahydrozoline HCl
Brand: Selleck Chemicals
SKU: S4043

Synonyms: Tetryzoline HCl

Catalog No.S4043 Purity: 99.96%

Tetrahydrozoline (Tetryzoline) HCl is an imidazoline derivative with alpha receptor agonist activity.

Tetrahydrozoline HCl Chemical Structure

CAS: 522-48-5

Purity & Quality Control

Batch: S404301 Water] 47 mg/mL] false] Ethanol] 26 mg/mL] false] DMSO] 12 mg/mL] false Purity: 99.96%

99.96

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Biological Activity

Description

Tetrahydrozoline (Tetryzoline) HCl is an imidazoline derivative with alpha receptor agonist activity.

Features

Tetrahydrozoline HCl is an alpha receptor agonist.

Targets

α-adrenergic receptor ^[1]

In vitro
In vitro	Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity. ^[1] Its main mechanism of action is the constriction of conjunctival blood vessels. ^[2]

In Vivo
In vivo	Tetrahydrozoline HCl inhibits settlement of the Barnacle Balanus improvisus at 1μM. ^[2]

References

Chemical lnformation & Solubility

Molecular Weight	236.74	Formula	C₁₃H₁₆N₂.HCl
CAS No.	522-48-5	SDF	Download Tetrahydrozoline HCl SDF
Smiles	C1CC(C2=CC=CC=C2C1)C3=NCCN3.Cl
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

Water : 47 mg/mL

Ethanol : 26 mg/mL

DMSO : 12 mg/mL ( (50.68 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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