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Sulfadoxine

Name: Sulfadoxine
Brand: Selleck Chemicals
SKU: S2511

Synonyms: Sulphadoxine

Catalog No.S2511 Purity: 99.5%

Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.

Sulfadoxine Chemical Structure

CAS: 2447-57-6

Purity & Quality Control

Batch: S251101 DMSO] 62 mg/mL] false] Water] Insoluble] false] Ethanol] Insoluble] false Purity: 99.5%

99.5

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Biological Activity

Description	Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT06162078	Recruiting	Maternal Malaria During Pregnancy - Baby Not Yet Delivered	Groupe de Recherche Action en Sante	August 25 2023	--
NCT05979896	Recruiting	Malaria	Malaria Consortium	July 28 2023	Phase 4
NCT05478954	Active not recruiting	Malaria	Malaria Consortium	July 15 2022	Phase 4
NCT05471544	Active not recruiting	Malaria	Malaria Consortium	July 18 2022	Phase 3
NCT04577469	Unknown status	Bioequivalence	Emzor Pharmaceutical Industries Limited	December 2020	Phase 1

Chemical lnformation & Solubility

Molecular Weight	310.33378	Formula	C₁₂H₁₄N₄O₄S
CAS No.	2447-57-6	SDF	Download Sulfadoxine SDF
Smiles	COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 62 mg/mL ( (199.78 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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