Home Immunology & Inflammation Anti-infection inhibitor - Src inhibitor - Syk inhibitor - TAK1 inhibitor Dehydroabietic acid For research use only.

Dehydroabietic acid

Synonyms: DAA, DHAA

Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.

Dehydroabietic acid Chemical Structure

Dehydroabietic acid Chemical Structure

CAS: 1740-19-8

Purity & Quality Control

Batch: S322601 DMSO] 100 mg/mL] false] ] ] false] ] ] false Purity: 99.45%
99.45

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Biological Activity

Description Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
Targets
Src [1] Syk [1] TAK1 [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05521880 Not yet recruiting Substance Use Disorders|Infection Soft Tissue|Bacteremia|Osteomyelitis Acute|Septic Arthritis University of Maryland Baltimore January 2024 Phase 4
NCT05506475 Not yet recruiting HIV Infection|Hepatitis C Infection Institut Pasteur|National Institute of Hygiene and Epidemiology Vietnam|ANRS Emerging Infectious Diseases September 2023 --
NCT05992077 Not yet recruiting HCV Infection ANRS Emerging Infectious Diseases August 7 2023 Not Applicable
NCT05713136 Not yet recruiting Hepatitis C Kirby Institute August 14 2023 --
NCT05248555 Recruiting Hepatitis C Kirby Institute January 16 2023 --

Chemical lnformation & Solubility

Molecular Weight 300.44 Formula

C20H28O2
CAS No. 1740-19-8 SDF --
Smiles CC(C)C1=CC2=C(C=C1)C3(C)CCCC(C)(C3CC2)C(O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (332.84 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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