Home DNA Damage/DNA Repair DNA/RNA Synthesis inhibitor - Nucleoside Analog/Antimetabolite inhibitor - Apoptosis related activator - Thymidylate Synthase inhibitor - HIV inhibitor 5-FU (5-Fluorouracil) For research use only.

5-FU (5-Fluorouracil)

Synonyms: Fluorouracil, NSC 19893

5-FU (5-Fluorouracil) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.

5-FU (5-Fluorouracil) Chemical Structure

5-FU (5-Fluorouracil) Chemical Structure

CAS: 51-21-8

Selleck's 5-FU (5-Fluorouracil) has been cited by 227 publications

Purity & Quality Control

Batch: Purity: 99.97%
99.97

Products often used together with 5-FU (5-Fluorouracil)

Oxaliplatin

5-Fluorouracil and Oxaliplatin, along with hepatic arterial infusion chemotherapy, is an acceptable and well-tolerated treatment for advanced gallbladder cancer.

Zheng K, et al. Cardiovasc Intervent Radiol. 2021 Feb;44(2):271-280.

Irinotecan

5-Fluorouracil and Irinotecan plus leucovorin as nanoliposomes are effective and tolerable in patients with metastatic pancreatic adenocarcinoma.

Yu HY, et al. J Chin Med Assoc. 2022 Jan 1;85(1):42-50.

Cisplatin

5-Fluorouracil and Cisplatin show high immunolabelling patterns of RANKL, TNF-α, and IL-1β in rats with experimental periodontitis (EP).

Novaes VCN, et al. Support Care Cancer. 2022 Mar;30(3):1967-1980.

Paclitaxel

Paclitaxel exhibits higher radiosensitization than 5-FU for LoVo colon cancer cell line cells and has potential as an alternative radiosensitizing agent to 5-FU for colon cancer.

Hiro J, et al. Oncol Rep. 2010 Oct;24(4):1029-34.

Doxorubicin (DOX) HCl

5-Fluorouracil and Doxorubicin significantly inhibits the progression of tumor growth in the MDA-MB-231 xenograft tumor mice model.

Han R, et al. J Drug Target. 2017 Feb;25(2):140-148.

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Cell Data

Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H292 Growth Inhibition Assay 72 h  IC50> 25 μg/mL 24095176
HL-60 Growth Inhibition Assay 72 h  IC50=8.601 μg/mL 24095176
HT-29 Growth Inhibition Assay 72 h  IC50> 25 μg/mL 24095176
MCF-7 Growth Inhibition Assay 72 h  IC50=20 μg/mL 24095176
L1210/0 Function assay Effect on L1210/0 cells in culture, IC50 = 0.3 μM. 2362278
CCRF-CEM Function assay Effect on CCRF-CEM cells in culture, IC50 = 2 μM. 2362278
P388 Antiproliferative assay 48 hrs Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay, IC50 = 0.609 μM. 2778449
HT-29 Antiproliferative assay 96 hrs Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay, IC50 = 0.69 μM. 2778449
L1210 Growth inhibition assay Inhibition of cell growth of L1210 mouse Leukemia cells, IC50 = 0.3 μM. 2967375
L1210 Growth inhibition assay Concentration required for the 50% inhibition of growth of L1210 mouse leukemia cells in culture, IC50 = 0.5 μM. 7120290
CCRF-CEM Growth inhibition assay Concentration required for the 50% inhibition of growth of CCRF-CEM human leukemia cells in culture, IC50 = 5 μM. 7120290
L1210 Growth inhibition assay 48 hrs In vitro growth inhibition of L1210 cells 48 hours after administration of compound, IC50 = 0.12 μM. 7629806
L1210 Growth inhibition assay 24 hrs In vitro growth inhibition of L1210 cells 24 hours after administration of compound, IC50 = 0.22 μM. 7629806
L1210 Growth inhibition assay 8 hrs In vitro growth inhibition of L1210 cells 8 hours after administration of compound, IC50 = 0.63 μM. 7629806
L1210 Growth inhibition assay 2 hrs In vitro growth inhibition of L1210 cells 2 hours after administration of compound, IC50 = 2.2 μM. 7629806
CHO Growth inhibition assay Growth inhibitory activity against CHO cells in culture., IC50 = 5 μM. 7853342
SCLC Cytotoxicity assay Cytotoxicity against human SCLC cells resistant to cisplatin (SCLC/CDDP), IC50 = 8.4 μM. 8258835
T-24 Cytotoxicity assay Tested for cytotoxicity against antigen negative T-24 bladder carcinoma cells having only 3-5% antigen expression, IC50 = 4.1 μM. 8496926
791T Cytotoxicity assay Tested for cytotoxicity against antigen positive 791T osteosarcoma cells having only 3-5% antigen expression, IC50 = 5.5 μM. 8496926
9L Anticancer assay Tested in vitro for anticancer activity against 9L cells, IC50 = 1 μM. 10072683
SK-MEL-28 Anticancer assay Tested in vitro for anticancer activity against SK-MEL-28 cells, IC50 = 4.5 μM. 10072683
PBM Cytotoxicity assay Tested in vitro for cytotoxicity against PBM cells, IC50 = 5 μM. 10072683
Vero Cytotoxicity assay Tested in vitro for cytotoxicity against Vero cells, IC50 = 6.81 μM. 10072683
SK-MES-1 Anticancer assay Tested in vitro for anticancer activity against SK-MES-1 cells, IC50 = 13.1 μM. 10072683
HepG2 Anticancer assay Tested in vitro for anticancer activity against HepG2 cells, IC50 = 37.9 μM. 10072683
MCF-7 Anticancer assay Tested in vitro for anticancer activity against MCF-7 cells, IC50 = 41 μM. 10072683
L1210 Cytotoxicity assay In vitro cytotoxicity against murine Leukemia L1210 cells., IC50 = 0.62 μM. 10229634
KB Cytotoxicity assay In vitro cytotoxicity against human oral epidermoid carcinoma KB cells., IC50 = 2.3 μM. 10229634
L1210 Growth inhibition assay Concentration required to inhibit 50% of cell growth on murine L1210 cells., IC50 = 0.28 μM. 11052798
P388 D1 Growth inhibition assay Concentration required to inhibit 50% of cell growth on murine P388 D1 cells., IC50 = 0.49 μM. 11052798
Molt 4/C8 Growth inhibition assay Concentration required to inhibit 50% of cell growth on human Molt 4/C8 cells., IC50 = 23 μM. 11052798
L1210 Growth inhibition assay 48 hrs Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 48 hr, IC50 = 0.125 μM. 11063625
L1210 Growth inhibition assay 24 hrs Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 24 hr, IC50 = 0.22 μM. 11063625
L1210 Growth inhibition assay 8 hrs Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 8 hr, IC50 = 0.63 μM. 11063625
L1210 Growth inhibition assay 2 hrs Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 2 hr, IC50 = 2.2 μM. 11063625
Colon 26-L5 Antiproliferative assay 72 hrs Antiproliferative activity against mouse Colon 26-L5 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.5 μM. 11575942
B16-BL6 Antiproliferative assay 72 hrs Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.6 μM. 11575942
HT1080 Antiproliferative assay 72 hrs Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.5 μM. 11575942
L1210 Growth inhibition assay 48 hrs Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment, IC50 = 0.2 μM. 11728193
L1210 Growth inhibition assay 24 hrs Growth inhibition in L1210 mouse leukemia cells after 24 h treatment, IC50 = 0.36 μM. 11728193
L1210 Growth inhibition assay 8 hrs Growth inhibition in L1210 mouse leukemia cells after 8 h treatment, IC50 = 1.01 μM. 11728193
L1210 Growth inhibition assay 2 hrs Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment, IC50 = 2.5 μM. 11728193
HL60 Function assay In vitro inhibitory concentration against proliferation of HL60 cells, IC50 = 1.5 μM. 12877593
HT1080 Antiproliferative assay 72 hrs Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 3.7 μM. 14640513
HCT116 Cytotoxicity assay 96 hrs Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay, IC50 = 4.93 μM. 15387639
DLD1 Cytotoxicity assay 96 hrs Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay, IC50 = 7.38 μM. 15387639
HeLaS3 Cytotoxicity assay 72 hrs Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay, IC50 = 5.4 μM. 15387656
HeLaS3 Cytotoxicity assay Cytotoxicity against human HeLaS3 cells by WST1 assay, IC50 = 5.4 μM. 15568771
MCF-7 Antiproliferative assay Antiproliferative activity in MCF-7 human breast cancer cells, IC50 = 4.8 μM. 15658875
MDA-MB 231 Antiproliferative assay Antiproliferative activity in MDA-MB 231 human breast cancer cells, IC50 = 9.6 μM. 15658875
A549 Cytotoxicity assay 96 hrs Cytotoxicity against human A549 cells after 96 hrs by MTT assay, IC50 = 1.4 μM. 16499317
HCT8 Cytotoxicity assay 96 hrs Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay, IC50 = 4.2 μM. 16499317
BEL-7402 Cytotoxicity assay 96 hrs Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay, IC50 = 4.2 μM. 16499317
A2780 Cytotoxicity assay 96 hrs Cytotoxicity against human A2780 cells after 96 hrs by MTT assay, IC50 = 5 μM. 16499317
BGC823 Cytotoxicity assay 96 hrs Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay, IC50 = 5.4 μM. 16499317
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells, IC50 = 2.04 μM. 16996657
COLO205 Cytotoxicity assay Cytotoxicity against human COLO205 cells, IC50 = 3.39 μM. 16996657
RPMI8226 Cytotoxicity assay Cytotoxicity against human RPMI8226 cells, IC50 = 3.55 μM. 16996657
HCC2998 Cytotoxicity assay Cytotoxicity against human HCC2998 cells, IC50 = 5.75 μM. 16996657
HCT15 Cytotoxicity assay Cytotoxicity against human HCT15 cells, IC50 = 6.61 μM. 16996657
KM12 Cytotoxicity assay Cytotoxicity against human KM12 cells, IC50 = 7.94 μM. 16996657
SW620 Cytotoxicity assay Cytotoxicity against human SW620 cells, IC50 = 18.6 μM. 16996657
KB Cytotoxicity assay 48 hrs Cytotoxicity against human KB cells after 48 hrs, IC50 = 13.4 μM. 17000031
HT29 Antiproliferative assay Antiproliferative activity against HT29 cells, IC50 = 7.3 μM. 17110105
Vero Cytotoxicity assay Cytotoxicity against Vero cells, IC50 = 0.2 μM. 17234303
SW1116 Cytotoxicity assay Cytotoxicity against SW1116 cells by MTT colometric method, IC50 = 37 μM. 17253861
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.16 μM. 17291040
Bel7402 Cytotoxicity assay 48 hrs Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay, IC50 = 23.21 μM. 17291040
BGC823 Cytotoxicity assay 48 hrs Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 31.16 μM. 17291040
HT29 Cytotoxicity assay Cytotoxicity against human HT29 cells by MTT microassay, IC50 = 0.6 μM. 17320246
Hep 3B Cytotoxicity assay Cytotoxicity against human Hep 3B cells by MTT microassay, IC50 = 0.6 μM. 17320246
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT microassay, IC50 = 1.5 μM. 17320246
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT microassay, IC50 = 3.1 μM. 17320246
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs, IC50 = 4.8 μM. 17336074
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs, IC50 = 9.6 μM. 17336074
Caco-2 Growth inhibition assay 10 days Growth inhibition of human Caco-2 cells after 10 days, IC50 = 1.5 μM. 17337193
L1210/0 Cytotoxicity assay 48 hrs Cytotoxicity against mouse L1210/0 cells after 48 hrs, IC50 = 0.31 μM. 17341060
HCT116 Antitumor assay Antitumor activity against human HCT116 cells, GI50 = 0.39811 μM. 17446077
NCI-H460 Antitumor assay Antitumor activity against human NCI-H460 cells, GI50 = 1 μM. 17446077
SF539 Antitumor assay Antitumor activity against human SF539 cells, GI50 = 1.25893 μM. 17446077
MCF7 Antitumor assay Antitumor activity against human MCF7 cells, GI50 = 1.58489 μM. 17446077
HCC2998 Antitumor assay Antitumor activity against human HCC2998 cells, GI50 = 1.58489 μM. 17446077
A549 Antitumor assay Antitumor activity against human A549 cells, GI50 = 1.99526 μM. 17446077
CAKI-1 Antitumor assay Antitumor activity against human CAKI-1 cells, GI50 = 3.98107 μM. 17446077
SR Antitumor assay Antitumor activity against human SR cells, GI50 = 3.98107 μM. 17446077
UO31 Antitumor assay Antitumor activity against human UO31 cells, GI50 = 5.01187 μM. 17446077
RPMI8226 Antitumor assay Antitumor activity against human RPMI8226 cells, GI50 = 5.01187 μM. 17446077
HCT15 Antitumor assay Antitumor activity against human HCT15 cells, GI50 = 6.30957 μM. 17446077
HT29 Antitumor assay Antitumor activity against human HT29 cells, GI50 = 6.30957 μM. 17446077
LOX IMVI Antitumor assay Antitumor activity against human LOX IMVI cells, GI50 = 6.30957 μM. 17446077
COLO205 Antitumor assay Antitumor activity against human COLO205 cells, GI50 = 6.30957 μM. 17446077
KM12 Antitumor assay Antitumor activity against human KM12 cells, GI50 = 10 μM. 17446077
ACHN Antitumor assay Antitumor activity against human ACHN cells, GI50 = 10 μM. 17446077
DU145 Antitumor assay Antitumor activity against human DU145 cells, GI50 = 10 μM. 17446077
A498 Antitumor assay Antitumor activity against human A498 cells, GI50 = 10 μM. 17446077
MDA-MB-435 Antitumor assay Antitumor activity against human MDA-MB-435 cells, GI50 = 10 μM. 17446077
MOLT4 Antitumor assay Antitumor activity against human MOLT4 cells, GI50 = 12.5892 μM. 17446077
NCI-H23 Antitumor assay Antitumor activity against human NCI-H23 cells, GI50 = 12.5892 μM. 17446077
IGROV1 Antitumor assay Antitumor activity against human IGROV1 cells, GI50 = 12.5892 μM. 17446077
UACC62 Antitumor assay Antitumor activity against human UACC62 cells, GI50 = 12.5892 μM. 17446077
SK-MEL-5 Antitumor assay Antitumor activity against human SK-MEL-5 cells, GI50 = 12.5892 μM. 17446077
786-0 Antitumor assay Antitumor activity against human 786-0 cells, GI50 = 12.5892 μM. 17446077
K562 Antitumor assay Antitumor activity against human K562 cells, GI50 = 19.9526 μM. 17446077
HOP62 Antitumor assay Antitumor activity against human HOP62 cells, GI50 = 19.9526 μM. 17446077
MALME-3M Antitumor assay Antitumor activity against human MALME-3M cells, GI50 = 19.9526 μM. 17446077
OVCAR8 Antitumor assay Antitumor activity against human OVCAR8 cells, GI50 = 19.9526 μM. 17446077
HL60 (TB) Antitumor assay Antitumor activity against human HL60 (TB) cells, GI50 = 19.9526 μM. 17446077
NCI-H322 Antitumor assay Antitumor activity against human NCI-H322 cells, GI50 = 19.9526 μM. 17446077
SN12C Antitumor assay Antitumor activity against human SN12C cells, GI50 = 25.1189 μM. 17446077
OVCAR-3 Antitumor assay Antitumor activity against human OVCAR-3 cells, GI50 = 25.1189 μM. 17446077
SW620 Antitumor assay Antitumor activity against human SW620 cells, GI50 = 25.1189 μM. 17446077
CCRF-CEM Antitumor assay Antitumor activity against human CCRF-CEM cells, GI50 = 31.6228 μM. 17446077
U251 Antitumor assay Antitumor activity against human U251 cells, GI50 = 39.8107 μM. 17446077
NCI-H522 Antitumor assay Antitumor activity against human NCI-H522 cells, GI50 = 39.8107 μM. 17446077
NCI/ADR-RES Antitumor assay Antitumor activity against human NCI/ADR-RES cells, GI50 = 39.8107 μM. 17446077
SW480 Antiproliferative assay 72 hrs Antiproliferative activity against human SW480 cells after 72 hrs by MTT method, IC50 = 8.1 μM. 17524655
MDA-MB-435S Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method, IC50 = 14.5 μM. 17524655
HCCLM7 Antiproliferative assay 72 hrs Antiproliferative activity against human HCCLM7 cells after 72 hrs by MTT method, IC50 = 18.6 μM. 17524655
Caco-2 Growth inhibition assay Growth inhibition of human Caco-2 cells, IC50 = 1.5 μM. 17548129
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs, IC50 = 0.3 μM. 17548198
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs, IC50 = 2.8 μM. 17548198
SW480 Antiproliferative assay 72 hrs Antiproliferative activity against human SW480 cells after 72 hrs, IC50 = 3.5 μM. 17548198
SW48 Antiproliferative assay 72 hrs Antiproliferative activity against human SW48 cells after 72 hrs, IC50 = 5.3 μM. 17548198
DLD1 Growth inhibition assay Growth inhibition of human DLD1 cells, IC50 = 4.5 μM. 17553685
Caco-2 Growth inhibition assay 10 days Growth inhibition of human Caco-2 cells after 10 days, IC50 = 1.5 μM. 17555969
colon cancer cell Cytotoxicity assay Cytotoxicity against human colon cancer cells, GI50 = 5.75 μM. 17562365
A549 Cytotoxicity assay 48 hrs Cytotoxicity against A549 cells after 48 hrs by MTT assay, IC50 = 9.2 μM. 17604394
L1210 Cytostatic activity assay Cytostatic activity against mouse L1210 cells, IC50 = 0.28 μM. 17931862
CEM Cytostatic activity assay Cytostatic activity against human CEM cells, IC50 = 9 μM. 17931862
Molt4/C8 Cytostatic activity assay Cytostatic activity against human Molt4/C8 cells, IC50 = 23 μM. 17931862
Caco-2 Growth inhibition assay 10 days Growth inhibition of human Caco-2 cells after 10 days, IC50 = 1.5 μM. 18037195
MCF7 Antiproliferative assay 3 days Antiproliferative activity against human MCF7 cells after 3 days by SRB assay, IC50 = 4.32 μM. 18069093
MCF7 Antiproliferative assay Antiproliferative activity against human MCF7 cells, IC50 = 4.32 μM. 18194866
embryonic cell Function assay Induction of cleavage arrest in embryonic cells of stage 8 Xenopus laevis blastulae, IC50 = 26.8 μM. 18271558
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells, IC50 = 18.7 μM. 18302336
L1210 Antiproliferative assay 2 days Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay, IC50 = 0.69 μM. 18424155
MCF7 Antiproliferative assay 3 days Antiproliferative activity against human MCF7 cells after 3 days by MTT assay, IC50 = 4.5 μM. 18424155
MiaPaCa2 Antiproliferative assay 3 days Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay, IC50 = 6.5 μM. 18424155
SW620 Antiproliferative assay 3 days Antiproliferative activity against human SW620 cells after 3 days by MTT assay, IC50 = 8.7 μM. 18424155
HepG2 Antiproliferative assay 3 days Antiproliferative activity against human HepG2 cells after 3 days by MTT assay, IC50 = 9.2 μM. 18424155
CEM Antiproliferative assay 3 days Antiproliferative activity against human CEM cells after 3 days by MTT assay, IC50 = 9.23 μM. 18424155
WI38 Cytotoxicity assay 3 days Cytotoxicity against human WI38 cells after 3 days by MTT assay, IC50 = 10 μM. 18424155
HeLa Antiproliferative assay 3 days Antiproliferative activity against human HeLa cells after 3 days by MTT assay, IC50 = 16 μM. 18424155
Molt4/C8 Antiproliferative assay 3 days Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay, IC50 = 20 μM. 18424155
colon 26-L5 Cytotoxicity assay 72 hrs Cytotoxicity against mouse colon 26-L5 cells after 72 hrs by MTT assay, IC50 = 0.46 μM. 18440233
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 0.77 μM. 18440233
LLC Cytotoxicity assay 72 hrs Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay, IC50 = 2.59 μM. 18440233
B16-BL6 Cytotoxicity assay 72 hrs Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay, IC50 = 5.78 μM. 18440233
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 9.19 μM. 18440233
HT1080 Cytotoxicity assay 72 hrs Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 9.45 μM. 18440233
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 6.36 μM. 18469809
A2780 Antiproliferative assay 72 hrs Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 7.21 μM. 18469809
COLO205 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs, IC50 = 11.63 μM. 18469809
U2OS Antiproliferative assay 72 hrs Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 13.18 μM. 18469809
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 13.77 μM. 18469809
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 18.24 μM. 18469809
SW480 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay, IC50 = 26.26 μM. 18469809
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 26.67 μM. 18469809
HCT116/E6 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human HCT116/E6 cells after 72 hrs by proliferative assay, IC50 = 28.91 μM. 18469809
A2780/E6 Antiproliferative assay 72 hrs Antiproliferative activity against p53 deficient human A2780/E6 cells after 72 hrs by proliferative assay, IC50 = 38.67 μM. 18469809
HL60 Antiproliferative assay 3 days Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining, GI50 = 3.8 μM. 18491866
HT29 Cytotoxicity assay Cytotoxicity against human HT29 cells by MTT assay, IC50 = 0.6 μM. 18606546
Hep3B Cytotoxicity assay Cytotoxicity against human Hep3B cells by MTT assay, IC50 = 0.6 μM. 18606546
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 1.5 μM. 18606546
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 3.1 μM. 18606546
HaCaT Growth inhibition assay 72 hrs Growth inhibition of human HaCaT cells after 72 hrs by MTT assay, IC50 = 0.4 μM. 18640746
H460 Growth inhibition assay 72 hrs Growth inhibition of human H460 cells after 72 hrs by MTT assay, IC50 = 2 μM. 18640746
HeLa Growth inhibition assay 72 hrs Growth inhibition of human HeLa cells after 72 hrs by MTT assay, IC50 = 4 μM. 18640746
SW620 Growth inhibition assay 72 hrs Growth inhibition of human SW620 cells after 72 hrs by MTT assay, IC50 = 9 μM. 18640746
MIAPaCa2 Growth inhibition assay 72 hrs Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay, IC50 = 10 μM. 18640746
MCF7 Growth inhibition assay 72 hrs Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, IC50 = 15 μM. 18640746
B16 Cytotoxicity assay Cytotoxicity against mouse B16 cells by MTT assay, IC50 = 8.73 μM. 18644718
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 10.85 μM. 18644718
SW480 Cytotoxicity assay Cytotoxicity against human SW480 cells by MTT assay, IC50 = 13.16 μM. 18644718
BEL-7402 Cytotoxicity assay Cytotoxicity against human BEL-7402 cells by MTT assay, IC50 = 14.41 μM. 18644718
BGC-7901 Cytotoxicity assay Cytotoxicity against human BGC-7901 cells by MTT assay, IC50 = 16.35 μM. 18644718
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50 = 21.38 μM. 18644718
3T3 Cytotoxicity assay 48 hrs Cytotoxicity against BALB mouse 3T3 cells after 48 hrs, GI50 = 1.54 μM. 18798609
H460 Cytotoxicity assay 48 hrs Cytotoxicity against human H460 cells after 48 hrs, GI50 = 4.1 μM. 18798609
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs, GI50 = 6.5 μM. 18798609
HT29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT29 cells after 48 hrs, GI50 = 8.9 μM. 18798609
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs, GI50 = 14.6 μM. 18798609
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs, GI50 = 15.4 μM. 18798609
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs, GI50 = 16.7 μM. 18798609
M14 Cytotoxicity assay 48 hrs Cytotoxicity against human M14 cells after 48 hrs, GI50 = 22.4 μM. 18798609
colon cancer cell Growth inhibition assay 48 hrs Growth inhibition of human Colon cancer cells after 48 hrs, GI50 = 8.37 μM. 18950904
leukemia cell Growth inhibition assay 48 hrs Growth inhibition of human leukemia cells after 48 hrs, GI50 = 15.09 μM. 18950904
prostate cancer cell Growth inhibition assay 48 hrs Growth inhibition of human prostate cancer cells after 48 hrs, GI50 = 22.7 μM. 18950904
renal cancer cell Growth inhibition assay 48 hrs Growth inhibition of human renal cancer cells after 48 hrs, GI50 = 45.6 μM. 18950904
KB Cytotoxicity assay Cytotoxicity against human KB cells by MTT assay, IC50 = 0.00446 μM. 19345581
NCI60 Growth inhibition assay Growth inhibition of human NCI60 cells, GI50 = 17.7 μM. 19398334
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by SRB method, IC50 = 20.8 μM. 19422203
PC3 Antiproliferative assay 48 hrs Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 0.016 μM. 19423198
A431 Antiproliferative assay 48 hrs Antiproliferative activity against human A431 cells after 48 hrs by MTT assay, IC50 = 0.018 μM. 19423198
MCF7 Antiproliferative assay 24 hrs Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 4.3 μM. 19560842
Bel7402 Antiproliferative assay 24 hrs Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay, IC50 = 4.7 μM. 19560842
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, GI50 = 10 μM. 19572613
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, GI50 = 15 μM. 19572613
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. 19618920
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15 μM. 19618920
SW1573 Growth inhibition assay 48 hrs Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.1 μM. 19664930
A2780 Growth inhibition assay 48 hrs Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.4 μM. 19664930
HBL100 Growth inhibition assay 48 hrs Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.5 μM. 19664930
HeLa Growth inhibition assay 48 hrs Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay, GI50 = 19 μM. 19664930
T47D Growth inhibition assay 48 hrs Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 29 μM. 19664930
Colon 26-L5 Cytotoxicity assay 72 hrs Cytotoxicity against mouse Colon 26-L5 cells after 72 hrs by MTT assay, IC50 = 0.41 μM. 19689125
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 0.44 μM. 19689125
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 5.91 μM. 19689125
B16-BL6 Cytotoxicity assay 72 hrs Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay, IC50 = 7.39 μM. 19689125
HT1080 Cytotoxicity assay 72 hrs Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 8.58 μM. 19689125
OVCAR-3 Anticancer assay 48 hrs Anticancer activity against human OVCAR-3 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.01585 μM. 19740574
SR Anticancer assay 48 hrs Anticancer activity against human SR cells after 48 hrs by sulforhodamine B assay, GI50 = 0.02399 μM. 19740574
RPMI8266 Anticancer assay 48 hrs Anticancer activity against human RPMI8266 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.04467 μM. 19740574
MALME-3M Anticancer assay 48 hrs Anticancer activity against human MALME-3M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05129 μM. 19740574
HCC2998 Anticancer assay 48 hrs Anticancer activity against human HCC2998 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05248 μM. 19740574
NCI-H460 Anticancer assay 48 hrs Anticancer activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05623 μM. 19740574
SF539 Anticancer assay 48 hrs Anticancer activity against human SF539 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.0631 μM. 19740574
Caki1 Anticancer assay 48 hrs Anticancer activity against human Caki1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. 19740574
MDA-MB-435 Anticancer assay 48 hrs Anticancer activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. 19740574
MCF7 Anticancer assay 48 hrs Anticancer activity against human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07943 μM. 19740574
HCT15 Anticancer assay 48 hrs Anticancer activity against human HCT15 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.10965 μM. 19740574
COLO205 Anticancer assay 48 hrs Anticancer activity against human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.15849 μM. 19740574
NCI-H322M Anticancer assay 48 hrs Anticancer activity against human NCI-H322M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. 19740574
HT-29 Anticancer assay 48 hrs Anticancer activity against human HT-29 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. 19740574
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.19055 μM. 19740574
KM12 Anticancer assay 48 hrs Anticancer activity against human KM12 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2138 μM. 19740574
HCT116 Anticancer assay 48 hrs Anticancer activity against human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. 19740574
SF295 Anticancer assay 48 hrs Anticancer activity against human SF295 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. 19740574
LOXIMVI Anticancer assay 48 hrs Anticancer activity against human LOXIMVI cells after 48 hrs by sulforhodamine B assay, GI50 = 0.24547 μM. 19740574
ACHN Anticancer assay 48 hrs Anticancer activity against human ACHN cells after 48 hrs by sulforhodamine B assay, GI50 = 0.29512 μM. 19740574
NCI/ADR-RES Anticancer assay 48 hrs Anticancer activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31623 μM. 19740574
NCI-H23 Anticancer assay 48 hrs Anticancer activity against human NCI-H23 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.33113 μM. 19740574
MOLT4 Anticancer assay 48 hrs Anticancer activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35481 μM. 19740574
DU145 Anticancer assay 48 hrs Anticancer activity against human DU145 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.36308 μM. 19740574
HOP62 Anticancer assay 48 hrs Anticancer activity against human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. 19740574
A498 Anticancer assay 48 hrs Anticancer activity against human A498 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. 19740574
SK-MEL-5 Anticancer assay 48 hrs Anticancer activity against human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.46774 μM. 19740574
SN12C Anticancer assay 48 hrs Anticancer activity against human SN12C cells after 48 hrs by sulforhodamine B assay, GI50 = 0.50119 μM. 19740574
UACC62 Anticancer assay 48 hrs Anticancer activity against human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.52481 μM. 19740574
786-0 Anticancer assay 48 hrs Anticancer activity against human 786-0 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.72444 μM. 19740574
U251 Anticancer assay 48 hrs Anticancer activity against human U251 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.91201 μM. 19740574
SW620 Anticancer assay 48 hrs Anticancer activity against human SW620 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.93325 μM. 19740574
M14 Anticancer assay 48 hrs Anticancer activity against human M14 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.97724 μM. 19740574
SK-MEL-28 Anticancer assay 48 hrs Anticancer activity against human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.02329 μM. 19740574
TK10 Anticancer assay 48 hrs Anticancer activity against human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.12202 μM. 19740574
IGROV1 Anticancer assay 48 hrs Anticancer activity against human IGROV1 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.23027 μM. 19740574
UO31 Anticancer assay 48 hrs Anticancer activity against human UO31 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.41254 μM. 19740574
SF268 Anticancer assay 48 hrs Anticancer activity against human SF268 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.58489 μM. 19740574
OVCAR8 Anticancer assay 48 hrs Anticancer activity against human OVCAR8 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.7378 μM. 19740574
HL-60(TB) Anticancer assay 48 hrs Anticancer activity against human HL-60(TB) cells after 48 hrs by sulforhodamine B assay, GI50 = 2.29087 μM. 19740574
PC3 Anticancer assay 48 hrs Anticancer activity against human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.34423 μM. 19740574
RXF393 Anticancer assay 48 hrs Anticancer activity against human RXF393 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.63027 μM. 19740574
K562 Anticancer assay 48 hrs Anticancer activity against human K562 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. 19740574
UACC257 Anticancer assay 48 hrs Anticancer activity against human UACC257 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. 19740574
SNB19 Anticancer assay 48 hrs Anticancer activity against human SNB19 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.80189 μM. 19740574
OVCAR4 Anticancer assay 48 hrs Anticancer activity against human OVCAR4 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.46684 μM. 19740574
MDA-MB-231 Anticancer assay 48 hrs Anticancer activity against human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay, GI50 = 6.60693 μM. 19740574
NCI-H522 Anticancer assay 48 hrs Anticancer activity against human NCI-H522 cells after 48 hrs by sulforhodamine B assay, GI50 = 7.24436 μM. 19740574
T47D Anticancer assay 48 hrs Anticancer activity against human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 8.12831 μM. 19740574
CCRF-CEM Anticancer assay 48 hrs Anticancer activity against human CCRF-CEM cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. 19740574
Hs 578T Anticancer assay 48 hrs Anticancer activity against human Hs 578T cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. 19740574
BT549 Anticancer assay 48 hrs Anticancer activity against human BT549 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.7152 μM. 19740574
OVCAR5 Anticancer assay 48 hrs Anticancer activity against human OVCAR5 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.9648 μM. 19740574
SKOV3 Anticancer assay 48 hrs Anticancer activity against human SKOV3 cells after 48 hrs by sulforhodamine B assay, GI50 = 21.8776 μM. 19740574
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 0.3 μM. 19743863
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by MTT assay, IC50 = 0.6 μM. 19743863
MES-SA Antiproliferative assay 72 hrs Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay, IC50 = 1.1 μM. 19743863
SW480 Antiproliferative assay 72 hrs Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay, IC50 = 2.1 μM. 19743863
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 2.6 μM. 19743863
UACC-812 Antiproliferative assay 72 hrs Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay, IC50 = 3.1 μM. 19743863
RL Antiproliferative assay 72 hrs Antiproliferative activity against human RL cells after 72 hrs by MTT assay, IC50 = 3.2 μM. 19743863
SW48 Antiproliferative assay 72 hrs Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay, IC50 = 4.4 μM. 19743863
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. 19795843
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15 μM. 19795843
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs MTT assay, IC50 = 12.5 μM. 19846302
HT1080 Cytotoxicity assay 72 hrs Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 5.2 μM. 19919052
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. 19919065
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15 μM. 19919065
COLO205 Growth inhibition assay 48 hrs Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, IC50 = 21 μM. 19939522
HCT116 Cytotoxicity assay 24 hrs Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay, IC50 = 3.03 μM. 20163895
MOLT4 Antitumor assay 24 hrs Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay, IC50 = 0.03 μM. 20211564
H460 Antitumor assay 24 hrs Antitumor activity against human H460 cells after 24 hrs by MTT assay, IC50 = 2 μM. 20211564
HCT116 Antitumor assay 24 hrs Antitumor activity against human HCT116 cells after 24 hrs by MTT assay, IC50 = 4 μM. 20211564
SW620 Antitumor assay 24 hrs Antitumor activity against human SW620 cells after 24 hrs by MTT assay, IC50 = 9 μM. 20211564
MCF7 Antitumor assay 24 hrs Antitumor activity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 15 μM. 20211564
colon cancer Antitumor assay 48 hrs Antitumor activity against human colon cancer cells after 48 hrs by SRB assay, GI50 = 8.4 μM. 20350811
leukemia Antitumor assay 48 hrs Antitumor activity against human leukemia cells after 48 hrs by SRB assay, GI50 = 15.1 μM. 20350811
prostate cancer Antitumor assay 48 hrs Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay, GI50 = 22.7 μM. 20350811
renal cancer Antitumor assay 48 hrs Antitumor activity against human renal cancer cells after 48 hrs by SRB assay, GI50 = 45.6 μM. 20350811
KB Cytotoxicity assay 3 days Cytotoxicity against human KB cells after 3 days by MTT assay, IC50 = 4.46 μM. 20356655
NCI-H460 Cytotoxicity assay Cytotoxicity against human NCI-H460 cells, GI50 = 2.3 μM. 20356752
3T3 Cytotoxicity assay Cytotoxicity against BALB mouse 3T3 cells, GI50 = 3 μM. 20356752
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells, GI50 = 4.5 μM. 20356752
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells, GI50 = 5.3 μM. 20356752
HT-29 Cytotoxicity assay Cytotoxicity against human HT-29 cells, GI50 = 14.9 μM. 20356752
M14 Cytotoxicity assay Cytotoxicity against human M14 cells, GI50 = 32.4 μM. 20356752
SFME Antiproliferative assay 24 hrs Antiproliferative activity against mouse SFME cells after 24 hrs by MTT assay, IC50 = 3.2 μM. 20398972
r/m HM-SFME-1 Antiproliferative assay 24 hrs Antiproliferative activity against mouse r/m HM-SFME-1 cells after 24 hrs by MTT assay, IC50 = 48.5 μM. 20398972
H460 Antiproliferative assay 24 hrs Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay, IC50 = 2.7 μM. 20403701
MDA231 Antiproliferative assay 24 hrs Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay, IC50 = 3.5 μM. 20403701
A549 Antiproliferative assay 24 hrs Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay, IC50 = 5.4 μM. 20403701
MCF7 Antiproliferative assay 24 hrs Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay, IC50 = 15.2 μM. 20403701
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. 20405881
SKBR3 Antiproliferative assay 48 hrs Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay, GI50 = 3 μM. 20438092
MCF7/BUS Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7/BUS cells expressing estrogen receptor after 48 hrs by SRB assay, GI50 = 6.2 μM. 20438092
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay, GI50 = 8.3 μM. 20438092
T47D Antiproliferative assay 48 hrs Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay, GI50 = 47 μM. 20438092
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 1.93 μM. 20494492
DU145 Cytotoxicity assay 72 hrs Cytotoxicity against human DU145 cells after 72 hrs by MTT assay, IC50 = 2.19 μM. 20494492
SGC7901 Cytotoxicity assay 72 hrs Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 2.95 μM. 20494492
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 9.7 μM. 20494492
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50 = 45.4 μM. 20494492
OVCAR-3 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR-3 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.01585 μM. 20850204
SR Growth inhibition assay 48 hrs Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay, GI50 = 0.02399 μM. 20850204
RPMI8266 Growth inhibition assay 48 hrs Growth inhibition of human RPMI8266 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.04467 μM. 20850204
MALME-3M Growth inhibition assay 48 hrs Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05129 μM. 20850204
HCC2998 Growth inhibition assay 48 hrs Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05248 μM. 20850204
NCI-H460 Growth inhibition assay 48 hrs Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05623 μM. 20850204
SF539 Growth inhibition assay 48 hrs Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.0631 μM. 20850204
Caki1 Growth inhibition assay 48 hrs Growth inhibition of human Caki1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. 20850204
MDA-MB-435 Growth inhibition assay 48 hrs Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. 20850204
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07943 μM. 20850204
HCT15 Growth inhibition assay 48 hrs Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.10965 μM. 20850204
COLO205 Growth inhibition assay 48 hrs Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.15849 μM. 20850204
HT-29 Growth inhibition assay 48 hrs Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. 20850204
NCI-H322M Growth inhibition assay 48 hrs Growth inhibition of human NCI-H322M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. 20850204
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.19055 μM. 20850204
KM12 Growth inhibition assay 48 hrs Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2138 μM. 20850204
HCT116 Growth inhibition assay 48 hrs Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. 20850204
SF295 Growth inhibition assay 48 hrs Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. 20850204
LOXIMVI Growth inhibition assay 48 hrs Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay, GI50 = 0.24547 μM. 20850204
ACHN Growth inhibition assay 48 hrs Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay, GI50 = 0.29512 μM. 20850204
NCI/ADR-RES Growth inhibition assay 48 hrs Growth inhibition of human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31623 μM. 20850204
NCI-H23 Growth inhibition assay 48 hrs Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.33113 μM. 20850204
MOLT4 Growth inhibition assay 48 hrs Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35481 μM. 20850204
DU145 Growth inhibition assay 48 hrs Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.36308 μM. 20850204
HOP62 Growth inhibition assay 48 hrs Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. 20850204
A498 Growth inhibition assay 48 hrs Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. 20850204
SK-MEL-5 Growth inhibition assay 48 hrs Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.46774 μM. 20850204
SN12C Growth inhibition assay 48 hrs Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay, GI50 = 0.50119 μM. 20850204
UACC62 Growth inhibition assay 48 hrs Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.52481 μM. 20850204
786-0 Growth inhibition assay 48 hrs Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.72444 μM. 20850204
U251 Growth inhibition assay 48 hrs Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.91201 μM. 20850204
SW620 Growth inhibition assay 48 hrs Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.93325 μM. 20850204
M14 Growth inhibition assay 48 hrs Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.97724 μM. 20850204
SK-MEL-28 Growth inhibition assay 48 hrs Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.02329 μM. 20850204
TK10 Growth inhibition assay 48 hrs Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.12202 μM. 20850204
IGROV1 Growth inhibition assay 48 hrs Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.23027 μM. 20850204
UO31 Growth inhibition assay 48 hrs Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.41254 μM. 20850204
SF268 Growth inhibition assay 48 hrs Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.58489 μM. 20850204
OVCAR8 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.7378 μM. 20850204
HL-60(TB) Growth inhibition assay 48 hrs Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay, GI50 = 2.29087 μM. 20850204
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.34423 μM. 20850204
RXF393 Growth inhibition assay 48 hrs Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.63027 μM. 20850204
K562 Growth inhibition assay 48 hrs Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. 20850204
UACC257 Growth inhibition assay 48 hrs Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. 20850204
SNB19 Growth inhibition assay 48 hrs Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.80189 μM. 20850204
OVCAR4 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.46684 μM. 20850204
MDA-MB-231 Growth inhibition assay 48 hrs Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay, GI50 = 6.60693 μM. 20850204
NCI-H522 Growth inhibition assay 48 hrs Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay, GI50 = 7.24436 μM. 20850204
T47D Growth inhibition assay 48 hrs Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 8.12831 μM. 20850204
CCRF-CEM Growth inhibition assay 48 hrs Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. 20850204
Hs 578T Growth inhibition assay 48 hrs Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. 20850204
BT549 Growth inhibition assay 48 hrs Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.7152 μM. 20850204
OVCAR5 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.9648 μM. 20850204
SKOV3 Growth inhibition assay 48 hrs Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay, GI50 = 21.8776 μM. 20850204
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 12 μM. 20873740
A2780 Antiproliferative assay 72 hrs Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 14 μM. 20873740
U2OS Antiproliferative assay 72 hrs Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 16 μM. 20873740
p53 deficient PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay, IC50 = 30 μM. 20873740
SF539 Antiproliferative assay 72 hrs Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 43 μM. 20873740
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 48 μM. 20873740
T3M4 Cytotoxicity assay Cytotoxicity against human T3M4 cells by crystal violet staining, IC50 = 0.33 μM. 20930123
Colo-357 Cytotoxicity assay Cytotoxicity against human Colo-357 cells by crystal violet staining, IC50 = 2.05 μM. 20930123
Patu-T Cytotoxicity assay Cytotoxicity against human Patu-T cells by crystal violet staining, IC50 = 2.08 μM. 20930123
Patu-S Cytotoxicity assay Cytotoxicity against human Patu-S cells by crystal violet staining, IC50 = 2.93 μM. 20930123
Aspc-1 Cytotoxicity assay Cytotoxicity against human Aspc-1 cells by crystal violet staining, IC50 = 2.97 μM. 20930123
PANC1 Cytotoxicity assay Cytotoxicity against human PANC1 cells by crystal violet staining, IC50 = 3.94 μM. 20930123
Patu-02 Cytotoxicity assay Cytotoxicity against human Patu-02 cells by crystal violet staining, IC50 = 3.95 μM. 20930123
DAN-G Cytotoxicity assay Cytotoxicity against human DAN-G cells by crystal violet staining, IC50 = 4.38 μM. 20930123
Patu-T Cytotoxicity assay Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining, IC50 = 33.2 μM. 20930123
Hep2 Anticancer assay 48 hrs Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.3 μM. 21074444
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 2.4 μM. 21074444
HCT15 Anticancer assay 48 hrs Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 3.6 μM. 21074444
502713 Anticancer assay 48 hrs Anticancer activity against human 502713 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 4.6 μM. 21074444
DU145 Anticancer assay 48 hrs Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 4.8 μM. 21074444
PC3 Anticancer assay 48 hrs Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 12 μM. 21074444
IMR32 Anticancer assay 48 hrs Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 18 μM. 21074444
MCF7 Cytotoxicity assay 3 days Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay, IC50 = 4.32 μM. 21126804
KB Cytotoxicity assay 48 hrs Cytotoxicity against human KB cells after 48 hrs by MTT assay, IC50 = 2.16 μM. 21131104
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 2.78 μM. 21131104
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 38 μM. 21131104
KB Cytotoxicity assay 3 days Cytotoxicity against human KB cells after 3 days by MTT assay, IC50 = 11.9 μM. 21144621
MGC803 Cytotoxicity assay 3 days Cytotoxicity against human MGC803 cells after 3 days by MTT assay, IC50 = 12.6 μM. 21144621
CNE2 Cytotoxicity assay 3 days Cytotoxicity against human CNE2 cells after 3 days by MTT assay, IC50 = 13.1 μM. 21144621
MCF7 Cytotoxicity assay 3 days Cytotoxicity against human MCF7 cells after 3 days by MTT assay, IC50 = 15.2 μM. 21144621
L1210 Cytotoxicity assay 2 days Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis, IC50 = 0.56 μM. 21232828
HeLa Cytotoxicity assay 4 days Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis, IC50 = 0.57 μM. 21232828
CEM Cytotoxicity assay 3 days Cytotoxicity against human CEM cells after 3 days by coulter counter analysis, IC50 = 14 μM. 21232828
HL60 Cytotoxicity assay 48 hrs Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 9.5 μM. 21250700
A549 Cytotoxicity assay 48 hrs Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 11.3 μM. 21250700
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 15.9 μM. 21273072
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs, IC50 = 4.7 μM. 21295381
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs, IC50 = 9.6 μM. 21295381
L1210 Function assay 24 hrs Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting, IC50 = 0.02 μM. 21330014
L1210 Function assay 24 hrs Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting, IC50 = 0.06 μM. 21330014
FM3A Cytostatic activity assay 2 days Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis, IC50 = 0.18 μM. 21330014
HeLa Cytostatic activity assay Cytostatic activity against human HeLa cells in presence of 20 uM 2'-deoxyuridine, IC50 = 0.18 μM. 21330014
L1210 Function assay 4 hrs Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting, IC50 = 0.22 μM. 21330014
L1210 Function assay 24 hrs Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting, IC50 = 0.37 μM. 21330014
HeLa Cytostatic activity assay 3 days Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis, IC50 = 0.45 μM. 21330014
L1210 Cytostatic activity assay Cytostatic activity against mouse L1210 cells in presence of 500 uM uracil, IC50 = 0.47 μM. 21330014
L1210 Cytostatic activity assay 2 days Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis, IC50 = 0.56 μM. 21330014
L1210 Function assay 4 hrs Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting, IC50 = 0.6 μM. 21330014
L1210 Cytostatic activity assay Cytostatic activity against mouse L1210 cells in presence of 500 uM uridine, IC50 = 0.62 μM. 21330014
L1210 Function assay Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting, IC50 = 0.97 μM. 21330014
HeLa Cytostatic activity assay Cytostatic activity against human HeLa cells in presence of 500 uM uracil, IC50 = 1 μM. 21330014
HeLa Cytostatic activity assay Cytostatic activity against human HeLa cells in presence of 500 uM uridine, IC50 = 1.1 μM. 21330014
L1210 Cytostatic activity assay Cytostatic activity against mouse L1210 cells in presence of 20 uM 2'-deoxyuridine, IC50 = 1.3 μM. 21330014
HeLa Cytostatic activity assay Cytostatic activity against human HeLa cells in presence of 20 uM thymidine, IC50 = 1.5 μM. 21330014
L1210 Function assay 24 hrs Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting, IC50 = 4.9 μM. 21330014
L1210 Function assay 15 mins Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting, IC50 = 7 μM. 21330014
CEM Cytostatic activity assay 3 days Cytostatic activity against human CEM cells after 3 days by coulter counting analysis, IC50 = 14 μM. 21330014
L1210 Cytostatic activity assay Cytostatic activity against mouse L1210 cells in presence of 20 uM thymidine, IC50 = 21 μM. 21330014
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 9.1 μM. 21381696
CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay, IC50 = 8 μM. 21439690
CEM Cytotoxicity assay 48 hrs Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay, IC50 = 15 μM. 21439690
CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CEM cells after 72 hrs by MTT assay, IC50 = 30 μM. 21439690
CEM Cytotoxicity assay 48 hrs Cytotoxicity against human CEM cells after 48 hrs by MTT assay, IC50 = 40 μM. 21439690
K562 Anticancer assay Anticancer activity against human K562 cells, IC50 = 2.4 μM. 21449610
COLO205 Anticancer assay Anticancer activity against human COLO205 cells, IC50 = 4.17 μM. 21449610
KM12 Anticancer assay Anticancer activity against human KM12 cells, IC50 = 8.32 μM. 21449610
HCT116 Anticancer assay Anticancer activity against human HCT116 cells, IC50 = 8.51 μM. 21449610
HCT15 Anticancer assay Anticancer activity against human HCT15 cells, IC50 = 9.71 μM. 21449610
HT-29 Anticancer assay Anticancer activity against human HT-29 cells, IC50 = 10.2 μM. 21449610
HCC2998 Anticancer assay Anticancer activity against human HCC2998 cells, IC50 = 13.5 μM. 21449610
CCRF-CEM Anticancer assay Anticancer activity against human CCRF-CEM cells, IC50 = 33.1 μM. 21449610
MIAPaCa2 Antiproliferative assay 72 hrs Antiproliferative activity against human MIAPaCa2 cells after 72 hrs, IC50 = 7.4 μM. 21458113
COLO320 Antiproliferative assay 72 hrs Antiproliferative activity against human COLO320 cells after 72 hrs, IC50 = 8.7 μM. 21458113
COLO320 Antiproliferative assay 48 hrs Antiproliferative activity against human COLO320 cells after 48 hrs, IC50 = 10 μM. 21458113
MIAPaCa2 Antiproliferative assay 48 hrs Antiproliferative activity against human MIAPaCa2 cells after 48 hrs, IC50 = 14 μM. 21458113
MCF7 Antitumor assay 72 hrs Antitumor activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.54 μM. 21486694
EC9706 Antitumor assay 72 hrs Antitumor activity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 20.3 μM. 21486694
SPC-A1 Antitumor assay 72 hrs Antitumor activity against human SPC-A1 cells after 72 hrs by MTT assay, IC50 = 26.92 μM. 21486694
PC3 Antitumor assay 72 hrs Antitumor activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 29.3 μM. 21486694
HeLa Antitumor assay 72 hrs Antitumor activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 41.46 μM. 21486694
ZR-75-1 Growth inhibition assay 48 hrs Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.3 μM. 21489802
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.4 μM. 21489802
COLO205 Growth inhibition assay 48 hrs Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.8 μM. 21489802
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.8 μM. 21489802
Gurav Growth inhibition assay 48 hrs Growth inhibition of human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 3.1 μM. 21489802
A2780 Growth inhibition assay 48 hrs Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.5 μM. 21489802
HOP62 Growth inhibition assay 48 hrs Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.1 μM. 21489802
KB Growth inhibition assay 48 hrs Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 5.2 μM. 21489802
DWD Growth inhibition assay 48 hrs Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 6.1 μM. 21489802
SiHa Growth inhibition assay 48 hrs Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay, GI50 = 6.3 μM. 21489802
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 12 μM. 21489802
SMMC7721 Cytotoxicity assay Cytotoxicity against human SMMC7721 cells, IC50 = 13 μM. 21495659
A549 Cytotoxicity assay Cytotoxicity against human A549 cells, IC50 = 13.7 μM. 21495659
Bel7402 Cytotoxicity assay Cytotoxicity against human Bel7402 cells, IC50 = 21.8 μM. 21495659
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 5.6 μM. 21515044
QGY Cytotoxicity assay Cytotoxicity against human QGY cells by MTT assay, IC50 = 14.1 μM. 21515044
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells by MTT assay, IC50 = 16.1 μM. 21515044
SW620 Antiproliferative assay 72 hrs Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 3.38 μM. 21524829
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 10.31 μM. 21524829
MIAPaCa2 Antiproliferative assay 72 hrs Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay, IC50 = 11.45 μM. 21524829
WI38 Antiproliferative assay 72 hrs Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 18.5 μM. 21524829
SKBR3 Antiproliferative assay 72 hrs Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay, IC50 = 38.25 μM. 21524829
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 42.01 μM. 21524829
PA1 Antiproliferative assay 48 hrs Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test, IC50 = 5 μM. 21530016
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test, IC50 = 15 μM. 21530016
HeLa Cytotoxicity assay 3 days Cytotoxicity against human HeLa cells after 3 days by MTT assay, IC50 = 4 μM. 21612935
MG63 Cytotoxicity assay 3 days Cytotoxicity against human MG63 cells after 3 days by MTT assay, IC50 = 8 μM. 21612935
L1210 Cytotoxicity assay 72 hrs Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay, IC50 = 0.0000011 μM. 21640594
P388 Cytotoxicity assay 72 hrs Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay, IC50 = 0.0000017 μM. 21640594
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.0000027 μM. 21640594
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 0.0000077 μM. 21640594
IEC-6 Cytotoxicity assay 6 days Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay, IC50 = 0.66 μM. 21684047
MCF10A Cytotoxicity assay 6 days Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay, IC50 = 0.73 μM. 21684047
HT-29 Cytotoxicity assay 6 days Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay, IC50 = 1.08 μM. 21684047
MCF7 Cytotoxicity assay 6 days Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay, IC50 = 4.32 μM. 21684047
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells, IC50 = 3.3 μM. 21774474
NCI-H460 Cytotoxicity assay Cytotoxicity against human NCI-H460 cells, IC50 = 8.5 μM. 21774474
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells, IC50 = 31 μM. 21774474
KB Cytotoxicity assay 3 days Cytotoxicity against human KB cells after 3 days by MTT assay, IC50 = 12.5 μM. 21843939
HeLa Cytostatic activity assay 72 hrs Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting, IC50 = 0.23 μM. 21892829
L1210 Cytostatic activity assay 48 hrs Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting, IC50 = 0.32 μM. 21892829
HeLa Cytostatic activity assay 72 hrs Cytostatic activity against human HeLa cells after 72 hrs by cell counting, IC50 = 0.54 μM. 21892829
CEM Cytostatic activity assay 72 hrs Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting, IC50 = 12 μM. 21892829
CEM/0 Cytostatic activity assay 72 hrs Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting, IC50 = 18 μM. 21892829
L1210 Cytostatic activity assay Cytostatic activity against mouse L1210 cells, IC50 = 0.49 μM. 21917363
HeLa Cytostatic activity assay Cytostatic activity against human HeLa cells, IC50 = 0.54 μM. 21917363
CEM Cytostatic activity assay Cytostatic activity against human CEM cells, IC50 = 18 μM. 21917363
A549 Cytotoxicity assay 3 days Cytotoxicity against human A549 cells after 3 days by MTT assay, IC50 = 0.42 μM. 22000925
HepG2 Cytotoxicity assay 3 days Cytotoxicity against human HepG2 cells after 3 days by MTT assay, IC50 = 2.7 μM. 22000925
BCG823 Cytotoxicity assay 3 days Cytotoxicity against human BCG823 cells after 3 days by MTT assay, IC50 = 6.15 μM. 22000925
colon cancer cell Cytotoxicity assay 48 hrs Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting, GI50 = 8.4 μM. 22056277
leukemia cell Cytotoxicity assay 48 hrs Cytotoxicity against human leukemia cells after 48 hrs by coulter counting, GI50 = 15.1 μM. 22056277
prostate cancer cell Cytotoxicity assay 48 hrs Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting, GI50 = 22.7 μM. 22056277
renal cancer cell Cytotoxicity assay 48 hrs Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting, GI50 = 45.6 μM. 22056277
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 9.67 μM. 22079378
KB Antiproliferative assay 72 hrs Antiproliferative activity against human KB cells after 72 hrs by MTT assay, IC50 = 9.85 μM. 22079378
GLC82 Antiproliferative assay 72 hrs Antiproliferative activity against human GLC82 cells after 72 hrs by MTT assay, IC50 = 15.5 μM. 22079378
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 16.6 μM. 22079378
CNE2 Antiproliferative assay 72 hrs Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay, IC50 = 17.2 μM. 22079378
HEK293 Cytotoxicity assay 2 days Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay, IC50 = 42.9 μM. 22093761
colon cancer cell Growth inhibition assay 48 hrs Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method, GI50 = 8.4 μM. 22119151
leukemia cell Growth inhibition assay 48 hrs Growth inhibition of human leukemia cells after 48 hrs by coulter counter method, GI50 = 15.1 μM. 22119151
prostate cancer cell Growth inhibition assay 48 hrs Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method, GI50 = 22.7 μM. 22119151
renal cancer cell Growth inhibition assay 48 hrs Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method, GI50 = 45.6 μM. 22119151
H460 Cytotoxicity assay 72 hrs Cytotoxicity against human H460 cells after 72 hrs by MTT assay, IC50 = 3 μM. 22130132
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 4 μM. 22130132
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 14 μM. 22130132
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 5.64 μM. 22182926
QGY7701 Cytotoxicity assay 24 hrs Cytotoxicity against human QGY7701 cells after 24 hrs by MTT assay, IC50 = 14.3 μM. 22182926
SW480 Cytotoxicity assay 24 hrs Cytotoxicity against human SW480 cells after 24 hrs by MTT assay, IC50 = 15.71 μM. 22182926
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 16.32 μM. 22182926
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs ny MTT assay, IC50 = 9 μM. 22200404
CNE2 Cytotoxicity assay 72 hrs Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay, IC50 = 13.5 μM. 22200404
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 15.92 μM. 22209486
NCI-H460 Cytotoxicity assay Cytotoxicity against human NCI-H460 cells, IC50 = 8 μM. 22283451
SMMC7721 Cytotoxicity assay Cytotoxicity against human SMMC7721 cells, IC50 = 15 μM. 22283451
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells, IC50 = 31 μM. 22283451
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 29 μM. 22304344
B16 Cytotoxicity assay 48 hrs Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay, IC50 = 33 μM. 22304344
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 34 μM. 22304344
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 35 μM. 22304344
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 43 μM. 22304344
SW1990 Cytotoxicity assay 48 hrs Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay, IC50 = 45 μM. 22304344
SR Cytotoxicity assay 48 hrs Cytotoxicity against human SR cells after 48 hrs by SRB assay, GI50 = 0.0238 μM. 22305543
NCI-H522 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay, GI50 = 7.28 μM. 22305543
WHCO1 Antiproliferative assay 48 hrs Antiproliferative activity against human WHCO1 cells after 48 hrs by MTT assay, IC50 = 7.9 μM. 22381354
HaCaT Cytostatic activity assay 72 hrs Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay, IC50 = 0.3 μM. 22405290
L1210 Cytostatic activity assay 2 days Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis, IC50 = 0.49 μM. 22405290
HeLa Cytostatic activity assay 3 days Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis, IC50 = 0.54 μM. 22405290
NCI-H460 Cytostatic activity assay 72 hrs Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 3 μM. 22405290
HCT116 Cytostatic activity assay 72 hrs Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 4 μM. 22405290
MCF7 Cytostatic activity assay 72 hrs Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 15 μM. 22405290
CEM Cytostatic activity assay 3 days Cytostatic activity against human CEM cells after 3 days by coulter counter analysis, IC50 = 18 μM. 22405290
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 3.42 μM. 22405648
Bcap37 Cytotoxicity assay 48 hrs Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 5.33 μM. 22405648
SGC7901 Cytotoxicity assay 48 hrs Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 7.11 μM. 22405648
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay, IC50 = 3.5 μM. 22409771
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay, IC50 = 5 μM. 22409771
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay, IC50 = 6 μM. 22409771
FOCUS Cytotoxicity assay 72 hrs Cytotoxicity against human FOCUS cells after 72 hrs by SRB assay, IC50 = 7.6 μM. 22409771
Mahlavu Cytotoxicity assay 72 hrs Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay, IC50 = 10 μM. 22409771
HuH7 Cytotoxicity assay 72 hrs Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay, IC50 = 30.7 μM. 22409771
K562 Cytotoxicity assay Cytotoxicity against human K562 cells, IC50 = 2.4 μM. 22409967
COLO205 Cytotoxicity assay Cytotoxicity against human COLO205 cells, IC50 = 4.17 μM. 22409967
KM12 Cytotoxicity assay Cytotoxicity against human KM12 cells, IC50 = 8.32 μM. 22409967
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells, IC50 = 8.51 μM. 22409967
HCT15 Cytotoxicity assay Cytotoxicity against human HCT15 cells, IC50 = 9.71 μM. 22409967
HT-29 Cytotoxicity assay Cytotoxicity against human HT-29 cells, IC50 = 10.2 μM. 22409967
HCC2998 Cytotoxicity assay Cytotoxicity against human HCC2998 cells, IC50 = 13.5 μM. 22409967
PC3 Antiproliferative assay 48 hrs Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.1 μM. 22424614
MOLT4 Antiproliferative assay 48 hrs Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay, IC50 = 3.2 μM. 22424614
MCF7 Antiproliferative assay 144 hrs Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method, IC50 = 4.7 μM. 22450132
HT-29 Antiproliferative assay 144 hrs Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method, IC50 = 7.3 μM. 22450132
MDA-MB-231 Antiproliferative assay 144 hrs Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method, IC50 = 9.6 μM. 22450132
PC9 Cytotoxicity assay 48 hrs Cytotoxicity against human PC9 cells after 48 hrs by MTT assay, IC50 = 23.47 μM. 22483608
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 31.72 μM. 22483608
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.05 μM. 22483608
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.31 μM. 22483608
A375 Cytotoxicity assay 48 hrs Cytotoxicity against human A375 cells after 48 hrs by MTT assay, IC50 = 46.55 μM. 22483608
SKHEP1 Growth inhibition assay 48 hrs Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay, GI50 = 6.3 μM. 22512908
NCI-H460 Growth inhibition assay 48 hrs Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay, GI50 = 6.5 μM. 22512908
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, GI50 = 8.2 μM. 22512908
MSC Growth inhibition assay 48 hrs Growth inhibition of human MSC cells after 48 hrs by SRB assay, GI50 = 8.92 μM. 22512908
IGROV1 Growth inhibition assay 48 hrs Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay, GI50 = 9.1 μM. 22512908
DU145 Growth inhibition assay 48 hrs Growth inhibition of human DU145 cells after 48 hrs by SRB assay, GI50 = 9.37 μM. 22512908
HUVEC Growth inhibition assay 48 hrs Growth inhibition of HUVEC cells after 48 hrs by SRB assay, GI50 = 9.72 μM. 22512908
HCT116 Growth inhibition assay 48 hrs Growth inhibition of human HCT116 cells after 48 hrs by SRB assay, GI50 = 9.9 μM. 22512908
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, GI50 = 9.9 μM. 22512908
OVCAR5 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay, GI50 = 20 μM. 22512908
HCT15 Growth inhibition assay 48 hrs Growth inhibition of human HCT15 cells after 48 hrs by SRB assay, GI50 = 21 μM. 22512908
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by SRB assay, GI50 = 21 μM. 22512908
MIAPaCa2 Growth inhibition assay 48 hrs Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, GI50 = 30 μM. 22512908
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 2.1 μM. 22537362
KB Cytotoxicity assay 48 hrs Cytotoxicity against human KB cells after 48 hrs by MTT assay, IC50 = 6.8 μM. 22537362
KB/VCR Cytotoxicity assay 48 hrs Cytotoxicity against human KB/VCR cells after 48 hrs by MTT assay, IC50 = 33.4 μM. 22537362
SW620 Antiproliferative assay 72 hrs Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 6.68 μM. 22555152
MIAPaCa2 Antiproliferative assay 72 hrs Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay, IC50 = 11.67 μM. 22555152
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 14.93 μM. 22555152
WI38 Antiproliferative assay 72 hrs Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 24.66 μM. 22555152
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells by after 48 hrs by MTT assay, IC50 = 5.64 μM. 22579780
SGC7901 Cytotoxicity assay 48 hrs Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay, IC50 = 6.04 μM. 22579780
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay, IC50 = 13.65 μM. 22579780
QGY7701 Cytotoxicity assay 48 hrs Cytotoxicity against human QGY7701 cells by after 48 hrs by MTT assay, IC50 = 14.3 μM. 22579780
SW480 Cytotoxicity assay 48 hrs Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay, IC50 = 15.71 μM. 22579780
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay, IC50 = 16.32 μM. 22579780
L02 Cytotoxicity assay 48 hrs Cytotoxicity against human L02 cells by after 48 hrs by MTT assay, IC50 = 46.57 μM. 22579780
SH-SY5Y Cytotoxicity assay 72 hrs Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay, IC50 = 1.09 μM. 22687745
L929 Cytotoxicity assay 72 hrs Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay, IC50 = 1.38 μM. 22687745
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 8.83 μM. 22687745
DU145 Cytotoxicity assay 72 hrs Cytotoxicity against human DU145 cells after 72 hrs by MTT assay, IC50 = 12.32 μM. 22687745
SGC7901 Cytotoxicity assay 72 hrs Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 14.49 μM. 22687745
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 15.99 μM. 22687745
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 32.22 μM. 22687745
NCI-H460 Cytotoxicity assay 72 hrs Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 2.4 μM. 22727445
BGC823 Cytotoxicity assay 72 hrs Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay, IC50 = 4.5 μM. 22727445
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 4.8 μM. 22727445
SGC7901 Cytotoxicity assay 72 hrs Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 6.3 μM. 22727445
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 12.5 μM. 22727445
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 8.28 μM. 22749192
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 14.2 μM. 22749192
CNE2 Cytotoxicity assay 72 hrs Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay, IC50 = 15.1 μM. 22749192
GLC82 Cytotoxicity assay 72 hrs Cytotoxicity against human GLC82 cells after 72 hrs by MTT assay, IC50 = 17.4 μM. 22749192
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 18.5 μM. 22749192
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method, IC50 = 4.7 μM. 22765897
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method, IC50 = 7.3 μM. 22765897
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method, IC50 = 9.6 μM. 22765897
HT1080 Cytotoxicity assay Cytotoxicity against human HT1080 cells by MTT assay, IC50 = 3.06 μM. 22801644
A375-S2 Cytotoxicity assay Cytotoxicity against human A375-S2 cells by MTT assay, IC50 = 9.92 μM. 22801644
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells by MTT assay, IC50 = 10.36 μM. 22801644
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 10.45 μM. 22801644
BGC823 Cytotoxicity assay Cytotoxicity against human BGC823 cells by MTT assay, IC50 = 15.65 μM. 22801644
Hep2 Cytotoxicity assay Cytotoxicity against human Hep2 cells by MTT assay, IC50 = 24.58 μM. 22801644
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 24.58 μM. 22801644
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 31.52 μM. 22801644
MDA231 Cytotoxicity assay Cytotoxicity against human MDA231 cells by MTT assay, IC50 = 31.57 μM. 22801644
PC3 Cytotoxicity assay Cytotoxicity against human PC3 cells by MTT assay, IC50 = 35.75 μM. 22801644
PC3M Cytotoxicity assay 48 hrs Cytotoxicity against human PC3M cells after 48 hrs by MTT assay, IC50 = 22.63 μM. 22809558
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.41 μM. 22809558
MKN45 Cytotoxicity assay 48 hrs Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay, IC50 = 41.73 μM. 22809558
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. 22809558
LoVo Antiproliferative assay 48 hrs Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay, IC50 = 3.3 μM. 22840493
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 12.8 μM. 22840493
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 16.2 μM. 22840493
IOSE-144 Antiproliferative assay 48 hrs Antiproliferative activity against human IOSE-144 cells after 48 hrs by MTT assay, IC50 = 25.6 μM. 22840493
CAMA1 Cytotoxicity assay 72 hrs Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay, IC50 = 1.28 μM. 22867707
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay, IC50 = 3.5 μM. 22867707
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay, IC50 = 5.7 μM. 22867707
FOCUS Cytotoxicity assay 72 hrs Cytotoxicity against human FOCUS cells incubated for 72 hrs by SRB assay, IC50 = 7.69 μM. 22867707
T47D Cytotoxicity assay 72 hrs Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay, IC50 = 8.91 μM. 22867707
MV Cytotoxicity assay 72 hrs Cytotoxicity against human MV cells incubated for 72 hrs by SRB assay, IC50 = 9.97 μM. 22867707
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay, IC50 = 18.7 μM. 22867707
MFE296 Cytotoxicity assay 72 hrs Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay, IC50 = 30.68 μM. 22867707
HuH7 Cytotoxicity assay 72 hrs Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay, IC50 = 30.7 μM. 22867707
BT20 Cytotoxicity assay 72 hrs Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay, IC50 = 47.3 μM. 22867707
COLO320 Cytotoxicity assay 72 hrs Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay, IC50 = 12.5 μM. 22955095
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining, IC50 = 4.7 μM. 22959205
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining, IC50 = 7.3 μM. 22959205
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining, IC50 = 9.6 μM. 22959205
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.06 μM. 22959518
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 0.28 μM. 22959518
U937 Cytotoxicity assay 72 hrs Cytotoxicity against human U937 cells after 72 hrs by MTT assay, IC50 = 1.07 μM. 22959518
colon cancer Antiproliferative assay 48 hrs Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis, GI50 = 8.4 μM. 22995621
leukemia Antiproliferative assay 48 hrs Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis, GI50 = 15.1 μM. 22995621
prostate cancer Antiproliferative assay 48 hrs Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis, GI50 = 22.7 μM. 22995621
renal cancer Antiproliferative assay 48 hrs Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis, GI50 = 45.6 μM. 22995621
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 9.5 μM. 23002924
MNK45 Cytotoxicity assay 48 hrs Cytotoxicity against human MNK45 cells after 48 hrs by MTT assay, IC50 = 12 μM. 23002924
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method, IC50 = 1.3 μM. 23018096
BGC823 Antiproliferative assay 48 hrs Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method, IC50 = 1.52 μM. 23018096
SW1116 Antiproliferative assay 48 hrs Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method, IC50 = 2.41 μM. 23018096
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT method, IC50 = 3.25 μM. 23018096
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay, IC50 = 4.21 μM. 23044370
HT1080 Cytotoxicity assay 48 hrs Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay, IC50 = 15.2 μM. 23067549
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 36.4 μM. 23067549
2008 Growth inhibition assay Growth inhibition of human 2008 cells by crystal violet assay, IC50 = 4.2 μM. 23075414
Vero Growth inhibition assay Growth inhibition of african green monkey Vero cells by crystal violet assay, IC50 = 4.5 μM. 23075414
A2780 Growth inhibition assay Growth inhibition of human A2780 cells by crystal violet assay, IC50 = 5.1 μM. 23075414
C13 Growth inhibition assay Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay, IC50 = 8.5 μM. 23075414
A2780/CP70 Growth inhibition assay Growth inhibition of cDDP-resistant human A2780/CP70 cells by crystal violet assay, IC50 = 12.3 μM. 23075414
MSC Growth inhibition assay 48 hrs Growth inhibition of human MSC cells after 48 hrs by SRB assay, GI50 = 0.001 μM. 23094992
MSC Growth inhibition assay 48 hrs Growth inhibition of human MSC cells after 48 hrs by SRB assay, TGI = 0.001 μM. 23094992
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, GI50 = 0.0029 μM. 23094992
HUVEC Growth inhibition assay 48 hrs Growth inhibition of human HUVEC cells after 48 hrs by SRB assay, GI50 = 0.0036 μM. 23094992
SKHEP1 Growth inhibition assay 48 hrs Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay, GI50 = 0.0076 μM. 23094992
IGROV1 Growth inhibition assay 48 hrs Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay, GI50 = 0.00812 μM. 23094992
BxPC3 Growth inhibition assay 48 hrs Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, TGI = 0.0084 μM. 23094992
HCT116 Growth inhibition assay 48 hrs Growth inhibition of human HCT116 cells after 48 hrs by SRB assay, GI50 = 0.0088 μM. 23094992
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by SRB assay, GI50 = 0.01045 μM. 23094992
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, GI50 = 0.0145 μM. 23094992
DU145 Growth inhibition assay 48 hrs Growth inhibition of human DU145 cells after 48 hrs by SRB assay, GI50 = 0.02 μM. 23094992
HCT15 Growth inhibition assay 48 hrs Growth inhibition of human HCT15 cells after 48 hrs by SRB assay, GI50 = 0.0211 μM. 23094992
OVCAR5 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay, GI50 = 0.0264 μM. 23094992
MIAPaCa2 Growth inhibition assay 48 hrs Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, GI50 = 0.0306 μM. 23094992
NHDF Growth inhibition assay 48 hrs Growth inhibition of human NHDF cells after 48 hrs by SRB assay, GI50 = 0.06202 μM. 23094992
U251 Growth inhibition assay 48 hrs Growth inhibition of human U251 cells after 48 hrs by SRB assay, GI50 = 0.0696 μM. 23094992
NHDF Growth inhibition assay 48 hrs Growth inhibition of human NHDF cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
MIAPaCa2 Growth inhibition assay 48 hrs Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
HUVEC Growth inhibition assay 48 hrs Growth inhibition of human HUVEC cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
OVCAR5 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
HL-60(TB) Growth inhibition assay 48 hrs Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay, GI50 = 0.1 μM. 23094992
HL-60(TB) Growth inhibition assay 48 hrs Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
U251 Growth inhibition assay 48 hrs Growth inhibition of human U251 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
DU145 Growth inhibition assay 48 hrs Growth inhibition of human DU145 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
SKHEP1 Growth inhibition assay 48 hrs Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
HCT15 Growth inhibition assay 48 hrs Growth inhibition of human HCT15 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
IGROV1 Growth inhibition assay 48 hrs Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
HCT116 Growth inhibition assay 48 hrs Growth inhibition of human HCT116 cells after 48 hrs by SRB assay, TGI = 0.1 μM. 23094992
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT method, IC50 = 1.54 μM. 23164710
BGC823 Cytotoxicity assay Cytotoxicity against human BGC823 cells by MTT method, IC50 = 3.84 μM. 23164710
Bel7042 Cytotoxicity assay Cytotoxicity against human Bel7042 cells by MTT method, IC50 = 3.85 μM. 23164710
HCT8 Cytotoxicity assay Cytotoxicity against human HCT8 cells by MTT method, IC50 = 5.38 μM. 23164710
A2780 Cytotoxicity assay Cytotoxicity against human A2780 cells by MTT method, IC50 = 5.4 μM. 23164710
NIH-H460 Cytotoxicity assay Cytotoxicity against human NIH-H460 cells by MTT method, IC50 = 7.12 μM. 23164710
HepG2 Cytotoxicity assay 24 hrs Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay, IC50 = 29.87 μM. 23202484
PA1 Cytotoxicity assay 24 hrs Cytotoxicity against human PA1 cells after 24 hrs by MTT assay, IC50 = 39.5 μM. 23202484
HCT15 Cytotoxicity assay 24 hrs Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay, IC50 = 45.01 μM. 23202484
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 17.2 μM. 23279864
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 21.9 μM. 23279864
SGC7901 Cytotoxicity assay 72 hrs Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 28.5 μM. 23279864
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay, IC50 = 3.56 μM. 23305919
B16F10 Anticancer assay 48 hrs Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay, IC50 = 21.41 μM. 23312949
SGC7901 Anticancer assay 48 hrs Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay, IC50 = 46.35 μM. 23312949
HeLa Antitumor assay 48 hrs Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay, IC50 = 14.78 μM. 23313635
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by MTT assay, IC50 = 5.64 μM. 23353737
QGY7701 Growth inhibition assay 48 hrs Growth inhibition of human QGY7701 cells after 48 hrs by MTT assay, IC50 = 14.3 μM. 23353737
HuH7 Growth inhibition assay 48 hrs Growth inhibition of human HuH7 cells after 48 hrs by MTT assay, IC50 = 15.85 μM. 23353737
HeLa Growth inhibition assay 48 hrs Growth inhibition of human HeLa cells after 48 hrs by MTT assay, IC50 = 16.32 μM. 23353737
L02 Growth inhibition assay 48 hrs Growth inhibition of human L02 cells after 48 hrs by MTT assay, IC50 = 46.57 μM. 23353737
EC109 Cytotoxicity assay 72 hrs Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.34 μM. 23353743
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 7.01 μM. 23353743
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 7.54 μM. 23353743
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 27.07 μM. 23353743
colon cancer Cytotoxicity assay 48 hrs Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay, GI50 = 8.4 μM. 23474899
leukemia Cytotoxicity assay 48 hrs Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay, GI50 = 15.1 μM. 23474899
prostate cancer Cytotoxicity assay 48 hrs Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay, GI50 = 22.7 μM. 23474899
renal cancer Cytotoxicity assay 48 hrs Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay, GI50 = 45.6 μM. 23474899
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 16.7 μM. 23490159
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 22.8 μM. 23490159
SGC7901 Cytotoxicity assay 48 hrs Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 28.9 μM. 23490159
THP1 Antiproliferative assay 48 hrs Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay, IC50 = 1 μM. 23501113
PC3 Antiproliferative assay 48 hrs Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.2 μM. 23501113
Hep2 Antiproliferative assay 48 hrs Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.5 μM. 23501113
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.9 μM. 23501113
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50 = 28 μM. 23535322
CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CEM cells after 72 hrs by MTT assay, IC50 = 32 μM. 23535322
A375-S2 Cytotoxicity assay 48 hrs Cytotoxicity against human A375-S2 cells after 48 hrs by MTT assay, IC50 = 6.67 μM. 23558238
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 7.34 μM. 23558238
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 10.05 μM. 23558238
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 11.5 μM. 23558238
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 23.55 μM. 23558238
U937 Cytotoxicity assay 48 hrs Cytotoxicity against human U937 cells after 48 hrs by MTT assay, IC50 = 23.93 μM. 23558238
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 27.76 μM. 23558238
HT1080 Cytotoxicity assay 48 hrs Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay, IC50 = 35.62 μM. 23558238
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 40.34 μM. 23558238
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 44.05 μM. 23558238
EC9706 Cytotoxicity assay 72 hrs Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 0.32 μM. 23644193
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 7.14 μM. 23644193
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.33 μM. 23644193
SMMC7721 Cytotoxicity assay 72 hrs Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 26.71 μM. 23644193
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.52 μM. 23644215
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay, IC50 = 6.35 μM. 23644215
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 3.52 μM. 23665106
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 5.53 μM. 23665106
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay, IC50 = 24.5 μM. 23665106
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 32.18 μM. 23665106
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 43.71 μM. 23665106
colon cancer Cytotoxicity assay 48 hrs Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis, GI50 = 8.4 μM. 23683592
leukemia Cytotoxicity assay 48 hrs Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis, GI50 = 15.1 μM. 23683592
prostate cancer Cytotoxicity assay 48 hrs Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis, GI50 = 22.7 μM. 23683592
renal cancer Cytotoxicity assay 48 hrs Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis, GI50 = 45.6 μM. 23683592
SH-SY5Y Cytotoxicity assay 72 hrs Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay, IC50 = 0.97 μM. 23685571
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 3.24 μM. 23685571
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 8.71 μM. 23685571
Vero Cytotoxicity assay 72 hrs Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay, IC50 = 9.71 μM. 23685571
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 10.14 μM. 23685571
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 24.96 μM. 23685571
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay, IC50 = 27.07 μM. 23735281
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay, IC50 = 31.44 μM. 23735281
COLO320DM Cytotoxicity assay 48 hrs Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay, IC50 = 2 μM. 23792352
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3.4 μM. 23792763
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 3.6 μM. 23792763
SW480 Cytotoxicity assay 72 hrs Cytotoxicity against human SW480 cells after 72 hrs by MTT assay, IC50 = 8.1 μM. 23792763
MDA-MB-435S Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay, IC50 = 14.5 μM. 23792763
LM7 Cytotoxicity assay 72 hrs Cytotoxicity against human LM7 cells after 72 hrs by MTT assay, IC50 = 18.6 μM. 23792763
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 6.92 μM. 23792764
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.54 μM. 23792764
SMMC7721 Cytotoxicity assay 72 hrs Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 9.78 μM. 23792764
EC109 Cytotoxicity assay 72 hrs Cytotoxicity against human EC109 cells after 72 hrs by MTT assay, IC50 = 10.61 μM. 23792764
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, IC50 = 24.76 μM. 23792764
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 5 μM. 23800391
Vero Antiproliferative assay 48 hrs Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay, IC50 = 8 μM. 23800391
WI38 Antiproliferative assay 48 hrs Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay, IC50 = 10 μM. 23800391
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 10 μM. 23800391
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 22.3 μM. 23867385
H460 Cytotoxicity assay 48 hrs Cytotoxicity against human H460 cells after 48 hrs by MTT assay, IC50 = 26.7 μM. 23867385
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 4.84 μM. 23867603
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by SRB assay, IC50 = 6.23 μM. 23867603
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay, IC50 = 6.53 μM. 23867603
OVCAR3 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.01 μM. 23887055
SR Growth inhibition assay 48 hrs Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay, GI50 = 0.02 μM. 23887055
RPMI8226 Growth inhibition assay 48 hrs Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.04 μM. 23887055
MALME-3M Growth inhibition assay 48 hrs Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05 μM. 23887055
HCC2998 Growth inhibition assay 48 hrs Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05 μM. 23887055
NCI-H460 Growth inhibition assay 48 hrs Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05 μM. 23887055
SF539 Growth inhibition assay 48 hrs Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.06 μM. 23887055
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07 μM. 23887055
CAKI-1 Growth inhibition assay 48 hrs Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07 μM. 23887055
MDA-MB-435 Growth inhibition assay 48 hrs Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07 μM. 23887055
HCT15 Growth inhibition assay 48 hrs Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.11 μM. 23887055
COLO205 Growth inhibition assay 48 hrs Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.15 μM. 23887055
HT-29 Growth inhibition assay 48 hrs Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17 μM. 23887055
A549/ATCC Growth inhibition assay 48 hrs Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay, GI50 = 0.18 μM. 23887055
KM12 Growth inhibition assay 48 hrs Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.21 μM. 23887055
HCT116 Growth inhibition assay 48 hrs Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22 μM. 23887055
SF295 Growth inhibition assay 48 hrs Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22 μM. 23887055
LOXIMVI Growth inhibition assay 48 hrs Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay, GI50 = 0.24 μM. 23887055
ACHN Growth inhibition assay 48 hrs Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay, GI50 = 0.29 μM. 23887055
NCI-ADR-RES Growth inhibition assay 48 hrs Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31 μM. 23887055
NCI-H23 Growth inhibition assay 48 hrs Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.33 μM. 23887055
A498 Growth inhibition assay 48 hrs Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35 μM. 23887055
MOLT4 Growth inhibition assay 48 hrs Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35 μM. 23887055
DU145 Growth inhibition assay 48 hrs Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.36 μM. 23887055
HOP62 Growth inhibition assay 48 hrs Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39 μM. 23887055
SK-MEL-5 Growth inhibition assay 48 hrs Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.46 μM. 23887055
SN12C Growth inhibition assay 48 hrs Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay, GI50 = 0.49 μM. 23887055
UACC62 Growth inhibition assay 48 hrs Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.52 μM. 23887055
786-0 Growth inhibition assay 48 hrs Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.72 μM. 23887055
U251 Growth inhibition assay 48 hrs Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.9 μM. 23887055
SW620 Growth inhibition assay 48 hrs Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.92 μM. 23887055
M14 Growth inhibition assay 48 hrs Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.98 μM. 23887055
SK-MEL-28 Growth inhibition assay 48 hrs Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.03 μM. 23887055
TK10 Growth inhibition assay 48 hrs Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.12 μM. 23887055
IGROV1 Growth inhibition assay 48 hrs Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.22 μM. 23887055
UO31 Growth inhibition assay 48 hrs Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.42 μM. 23887055
SF268 Growth inhibition assay 48 hrs Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.62 μM. 23887055
OVCAR8 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.74 μM. 23887055
HL-60(TB) Growth inhibition assay 48 hrs Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay, GI50 = 2.3 μM. 23887055
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.36 μM. 23887055
RXF393 Growth inhibition assay 48 hrs Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.61 μM. 23887055
UACC257 Growth inhibition assay 48 hrs Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.55 μM. 23887055
K562 Growth inhibition assay 48 hrs Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.58 μM. 23887055
SNB19 Growth inhibition assay 48 hrs Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.81 μM. 23887055
OVCAR4 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.43 μM. 23887055
MDA-MB-231 Growth inhibition assay 48 hrs Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay, GI50 = 6.6 μM. 23887055
NCI-H522 Growth inhibition assay 48 hrs Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay, GI50 = 7.27 μM. 23887055
T47D Growth inhibition assay 48 hrs Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 8.12 μM. 23887055
Hs 578T Growth inhibition assay 48 hrs Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77 μM. 23887055
CCRF-CEM Growth inhibition assay 48 hrs Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay, GI50 = 9.79 μM. 23887055
BT549 Growth inhibition assay 48 hrs Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.6 μM. 23887055
OVCAR5 Growth inhibition assay 48 hrs Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.9 μM. 23887055
SKOV3 Growth inhibition assay 48 hrs Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay, GI50 = 21.8 μM. 23887055
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 5.62 μM. 23920246
SGC7901 Cytotoxicity assay 48 hrs Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 6.04 μM. 23920246
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 13.65 μM. 23920246
QGY7701 Cytotoxicity assay 48 hrs Cytotoxicity against human QGY7701 cells after 48 hrs by MTT assay, IC50 = 14.3 μM. 23920246
SW480 Cytotoxicity assay 48 hrs Cytotoxicity against human SW480 cells after 48 hrs by MTT assay, IC50 = 15.71 μM. 23920246
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 16.52 μM. 23920246
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by SRB assay, GI50 = 3.6 μM. 23964677
SKOV3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 24.43 μM. 23988357
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 29.98 μM. 23988357
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 34.33 μM. 23988357
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 44.04 μM. 23988357
leukemia Cytotoxicity assay 48 hrs Cytotoxicity against human leukemia cells after 48 hrs by SRB assay, GI50 = 1.51 μM. 23994328
colon cancer Cytotoxicity assay 48 hrs Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay, GI50 = 8.4 μM. 23994328
prostate cancer Cytotoxicity assay 48 hrs Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay, GI50 = 22.7 μM. 23994328
renal cancer Cytotoxicity assay 48 hrs Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay, GI50 = 45.6 μM. 23994328
A375-S2 Growth inhibition assay 48 hrs Growth inhibition against human A375-S2 cells after 48 hrs by MTT assay, IC50 = 6.67 μM. 23999046
HeLa Growth inhibition assay 48 hrs Growth inhibition against human HeLa cells after 48 hrs by MTT assay, IC50 = 7.34 μM. 23999046
HL60 Growth inhibition assay 48 hrs Growth inhibition against human HL60 cells after 48 hrs by MTT assay, IC50 = 10.05 μM. 23999046
MCF7 Growth inhibition assay 48 hrs Growth inhibition against human MCF7 cells after 48 hrs by MTT assay, IC50 = 11.5 μM. 23999046
K562 Growth inhibition assay 48 hrs Growth inhibition against human K562 cells after 48 hrs by MTT assay, IC50 = 23.55 μM. 23999046
U937 Growth inhibition assay 48 hrs Growth inhibition against human U937 cells after 48 hrs by MTT assay, IC50 = 23.93 μM. 23999046
HCT116 Growth inhibition assay 48 hrs Growth inhibition against human HCT116 cells after 48 hrs by MTT assay, IC50 = 27.76 μM. 23999046
HT1080 Growth inhibition assay 48 hrs Growth inhibition against human HT1080 cells after 48 hrs by MTT assay, IC50 = 35.62 μM. 23999046
HepG2 Growth inhibition assay 48 hrs Growth inhibition against human HepG2 cells after 48 hrs by MTT assay, IC50 = 40.34 μM. 23999046
A549 Growth inhibition assay 48 hrs Growth inhibition against human A549 cells after 48 hrs by MTT assay, IC50 = 44.05 μM. 23999046
QSG7701 Cytotoxicity assay 48 hrs Cytotoxicity against human QSG7701 cells after 48 hrs by CCK-8 assay, IC50 = 0.6 μM. 24013415
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay, IC50 = 12.48 μM. 24013415
SMMC7721 Cytotoxicity assay 48 hrs Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay, IC50 = 14.55 μM. 24013415
QGY7703 Cytotoxicity assay 48 hrs Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay, IC50 = 15.66 μM. 24013415
Hep Cytotoxicity assay 48 hrs Cytotoxicity against human Hep cells after 48 hrs by SRB assay, IC50 = 0.5 μM. 24056146
IMR32 Cytotoxicity assay 48 hrs Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay, IC50 = 1.3 μM. 24056146
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 1.1 μM. 24060486
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.1 μM. 24060486
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 1.2 μM. 24060486
DU145 Cytotoxicity assay 24 hrs Cytotoxicity against human DU145 cells after 24 hrs by MTT assay, IC50 = 1.3 μM. 24060486
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 6.92 μM. 24077182
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 7.54 μM. 24077182
SMMC7721 Cytotoxicity assay 72 hrs Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 9.78 μM. 24077182
EC109 Cytotoxicity assay 72 hrs Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 10.61 μM. 24077182
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 24.76 μM. 24077182
HCT8 Antiproliferative assay Antiproliferative activity against human HCT8 cells by MTT assay, IC50 = 6.92 μM. 24095094
Bel7402 Antiproliferative assay Antiproliferative activity against human Bel7402 cells by MTT assay, IC50 = 8.3 μM. 24095094
A549 Antiproliferative assay Antiproliferative activity against human A549 cells by MTT assay, IC50 = 8.92 μM. 24095094
SKOV3 Cytotoxicity assay 3 days Cytotoxicity against human SKOV3 cells after 3 days by MTT assay, IC50 = 24.43 μM. 24095745
HepG2 Cytotoxicity assay 3 days Cytotoxicity against human HepG2 cells after 3 days by MTT assay, IC50 = 29.98 μM. 24095745
A549 Cytotoxicity assay 3 days Cytotoxicity against human A549 cells after 3 days by MTT assay, IC50 = 34.33 μM. 24095745
NCI-H460 Cytotoxicity assay 3 days Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay, IC50 = 44.04 μM. 24095745
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 3.68 μM. 24119869
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 4.35 μM. 24119869
Bcap37 Cytotoxicity assay 48 hrs Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 5.58 μM. 24119869
SGC7901 Cytotoxicity assay 48 hrs Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 7.37 μM. 24119869
DU145 Cytotoxicity assay Cytotoxic activity against human DU145 cells, IC50 = 3.4 μM. 24195466
NCI-H460 Cytotoxicity assay Cytotoxic activity against human NCI-H460 cells, IC50 = 8.5 μM. 24195466
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 8.32 μM. 24211021
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 15.32 μM. 24211021
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 19.45 μM. 24211021
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 20.13 μM. 24211021
NCI-H460 Cytotoxicity assay 72 hrs Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 23.32 μM. 24211021
SW1116 Cytotoxicity assay 48 hrs Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay, IC50 = 5.26 μM. 24286761
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 7.43 μM. 24286761
BGC823 Cytotoxicity assay 48 hrs Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 7.48 μM. 24286761
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 9.79 μM. 24286761
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 3.5 μM. 24332497
B16 Cytotoxicity assay 48 hrs Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay, IC50 = 4.2 μM. 24332497
ME180 Cytotoxicity assay 48 hrs Cytotoxicity against human ME180 cells after 48 hrs by MTT assay, IC50 = 4.9 μM. 24332497
A549 Cytotoxicity assay 4 days Cytotoxicity against human A549 cells after 4 days by MTT assay, IC50 = 3.1 μM. 24359303
Bel7402 Cytotoxicity assay 4 days Cytotoxicity against human Bel7402 cells after 4 days by MTT assay, IC50 = 5.5 μM. 24359303
KB Cytotoxicity assay 4 days Cytotoxicity against human KB cells after 4 days by MTT assay, IC50 = 8.1 μM. 24359303
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 5.78 μM. 24378217
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 29.98 μM. 24378217
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 35.34 μM. 24378217
CNE Cytotoxicity assay 48 hrs Cytotoxicity against human CNE cells after 48 hrs by MTT assay, IC50 = 40.21 μM. 24378217
SPCA2 Cytotoxicity assay 48 hrs Cytotoxicity against human SPCA2 cells after 48 hrs by MTT assay, IC50 = 42.2 μM. 24378217
colon cancer Cytotoxicity assay 10 uM 48 hrs Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs, GI50 = 8.4 μM. 24469112
leukemia Cytotoxicity assay 10 uM 48 hrs Cytotoxicity against human leukemia cells at 10 uM after 48 hrs, GI50 = 15.1 μM. 24469112
prostate cancer Cytotoxicity assay 10 uM 48 hrs Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs, GI50 = 22.7 μM. 24469112
renal cancer Cytotoxicity assay 10 uM 48 hrs Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs, GI50 = 45.6 μM. 24469112
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay, IC50 = 14.3 μM. 24534537
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells after 48 hrs by trypan blue exclusion assay, IC50 = 14.3 μM. 24534537
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells after 48 hrs by MTT assay, IC50 = 15.7 μM. 24534537
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells after 48 hrs by LDH release assay, IC50 = 15.8 μM. 24534537
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay, IC50 = 16.3 μM. 24534537
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay, IC50 = 16.4 μM. 24534537
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.3 μM. 24547794
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 7.6 μM. 24547794
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 24.43 μM. 24565905
SKOV3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 24.43 μM. 24565905
Bel7404 Cytotoxicity assay 48 hrs Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay, IC50 = 26.8 μM. 24565905
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 26.98 μM. 24565905
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 36.04 μM. 24565905
H3347 Cytotoxicity assay 72 hrs Cytotoxicity against human H3347 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay, IC50 = 11.64 μM. 24583355
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay, IC50 = 24.87 μM. 24583355
DLD1 Cytotoxicity assay 72 hrs Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay, IC50 = 29.14 μM. 24583355
L1210 Cytotoxicity assay 48 hrs Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay, IC50 = 0.33 μM. 24631358
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay, IC50 = 0.54 μM. 24631358
CCRF-CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay, IC50 = 18 μM. 24631358
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.8 μM. 24641975
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.8 μM. 24641975
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.9 μM. 24641975
DU145 Cytotoxicity assay 24 hrs Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.9 μM. 24641975
COLO205 Cytotoxicity assay 24 hrs Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 3.39 μM. 24657568
RPMI8226 Antileukemic assay 24 hrs Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 3.55 μM. 24657568
HCC2998 Cytotoxicity assay 24 hrs Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 5.75 μM. 24657568
HCT15 Cytotoxicity assay 24 hrs Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 6.61 μM. 24657568
KM12 Cytotoxicity assay 24 hrs Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 7.94 μM. 24657568
SW620 Cytotoxicity assay 24 hrs Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 18.6 μM. 24657568
NCI60 Cytotoxicity assay 24 hrs Cytotoxicity against human NCI60 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 29.5 μM. 24657568
E0771 Cytotoxicity assay 3 days Cytotoxicity against mouse E0771 cells after 3 days by SRB assay, IC50 = 0.28 μM. 24704691
HT-29 Cytotoxicity assay 3 days Cytotoxicity against human HT-29 cells after 3 days by SRB assay, IC50 = 2.58 μM. 24704691
MCF7 Cytotoxicity assay 3 days Cytotoxicity against human MCF7 cells after 3 days by SRB assay, IC50 = 2.86 μM. 24704691
SW480 Cytotoxicity assay 3 days Cytotoxicity against human SW480 cells after 3 days by SRB assay, IC50 = 3.69 μM. 24704691
RKO Cytotoxicity assay 3 days Cytotoxicity against human RKO cells after 3 days by SRB assay, IC50 = 4.39 μM. 24704691
MCF10A Cytotoxicity assay 3 days Cytotoxicity against human MCF10A cells after 3 days by SRB assay, IC50 = 8.06 μM. 24704691
CCD-18Co Cytotoxicity assay 3 days Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay, IC50 = 9.26 μM. 24704691
T47D Cytotoxicity assay 3 days Cytotoxicity against human T47D cells after 3 days by SRB assay, IC50 = 10.56 μM. 24704691
MDA-MB-231 Cytotoxicity assay 3 days Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay, IC50 = 18.12 μM. 24704691
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay, IC50 = 0.98 μM. 24727462
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells after 2 days by MTT assay, IC50 = 7.34 μM. 24767839
MCF7 Cytotoxicity assay 2 days Cytotoxicity against human MCF7 cells after 2 days by MTT assay, IC50 = 11.5 μM. 24767839
HT-29 Cytotoxicity assay 2 days Cytotoxicity against human HT-29 cells after 2 days by MTT assay, IC50 = 17.2 μM. 24767839
A549 Cytotoxicity assay 2 days Cytotoxicity against human A549 cells after 2 days by MTT assay, IC50 = 44.05 μM. 24767839
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by SRB assay, GI50 = 4.55 μM. 24797798
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, IC50 = 4.68 μM. 24798098
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.76 μM. 24798098
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 8.13 μM. 24798098
EC109 Cytotoxicity assay 72 hrs Cytotoxicity against human EC109 cells after 72 hrs by MTT assay, IC50 = 24.14 μM. 24798098
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.08 μM. 24819956
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 10.54 μM. 24819956
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 11.12 μM. 24819956
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 1.3 μM. 24835633
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.3 μM. 24835633
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 1.4 μM. 24835633
DU145 Cytotoxicity assay 24 hrs Cytotoxicity against human DU145 cells after 24 hrs by MTT assay, IC50 = 1.5 μM. 24835633
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 3.52 μM. 24835817
EC9706 Antiproliferative assay 48 hrs Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay, IC50 = 9.45 μM. 24835817
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 11.34 μM. 24835817
L1210 Cytostatic activity assay 48 hrs Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method, IC50 = 0.33 μM. 24906510
HeLa Cytostatic activity assay 72 hrs Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method, IC50 = 0.54 μM. 24906510
CEM Cytostatic activity assay 72 hrs Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method, IC50 = 18 μM. 24906510
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.2 μM. 24910974
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.5 μM. 24910974
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay, IC50 = 4.9 μM. 24910974
WM266.4 Antiproliferative assay 24 hrs Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay, GI50 = 28.76 μM. 24934992
HeLa Antiproliferative assay 24 hrs Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay, GI50 = 30.21 μM. 24934992
MDA-MB-231 Antiproliferative assay 48 hrs Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 2.45 μM. 24941129
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.78 μM. 24941129
KCL22 Antiproliferative assay 48 hrs Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay, IC50 = 3.52 μM. 24941129
KB Cytotoxicity assay 48 hrs Cytotoxicity against human KB cells after 48 hrs by MTT assay, IC50 = 1.23 μM. 24953029
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 10.05 μM. 24953029
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 23.33 μM. 24953029
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 34.34 μM. 24953029
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 38.34 μM. 24953029
CNE Cytotoxicity assay 48 hrs Cytotoxicity against human CNE cells after 48 hrs by MTT assay, IC50 = 45.1 μM. 24953029
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 45.14 μM. 24953029
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 46.93 μM. 24953029
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.21 μM. 24956552
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 12 μM. 24956552
A549 Cytotoxicity assay 24 to 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay, IC50 = 1.65 μM. 24996138
MGC803 Anticancer assay 72 hrs Anticancer activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 3.45 μM. 25001482
MCF7 Anticancer assay 72 hrs Anticancer activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.12 μM. 25001482
EC9706 Anticancer assay 72 hrs Anticancer activity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 8.07 μM. 25001482
SSMC-7721 Anticancer assay 72 hrs Anticancer activity against human SSMC-7721 cells after 72 hrs by MTT assay, IC50 = 15.08 μM. 25001482
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 24.6 μM. 25016234
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.41 μM. 25016234
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 39.88 μM. 25016234
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. 25016234
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay, IC50 = 0.5 μM. 25066282
SW620 Cytotoxicity assay 72 hrs Cytotoxicity against human SW620 cells after 72 hrs by MTS assay, IC50 = 5.3 μM. 25066282
MCF7 Anticancer assay 72 hrs Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 4.6 μM. 25086915
EC9706 Anticancer assay 72 hrs Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 4.7 μM. 25086915
MGC803 Anticancer assay 72 hrs Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 10 μM. 25086915
HeLa Anticancer assay 72 hrs Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 12 μM. 25086915
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 7.62 μM. 25113877
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 7.76 μM. 25113877
CNE Antiproliferative assay 48 hrs Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 15.07 μM. 25113877
Bel7402 Antiproliferative assay 48 hrs Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 19.84 μM. 25113877
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 29.98 μM. 25151580
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 35.34 μM. 25151580
SMMC-7404 Cytotoxicity assay 48 hrs Cytotoxicity against human SMMC-7404 cells after 48 hrs by MTT assay, IC50 = 40.21 μM. 25151580
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 44.04 μM. 25151580
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 46.93 μM. 25151580
B16 Antiproliferative assay 48 hrs Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay, IC50 = 17.85 μM. 25164762
HL60 Antiproliferative assay 48 hrs Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 27.01 μM. 25164762
Hep Cytotoxicity assay 48 hrs Cytotoxicity against human Hep cells after 48 hrs by SRB assay, IC50 = 0.5 μM. 25176329
IMR32 Cytotoxicity assay 48 hrs Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay, IC50 = 1.3 μM. 25176329
B16F10 Cytotoxicity assay 72 hrs Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 0.87 μM. 25180925
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 7.69 μM. 25180925
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 8.93 μM. 25180925
EC109 Cytotoxicity assay 72 hrs Cytotoxicity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 10.81 μM. 25180925
HEK293 Antiproliferative assay 24 hrs Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay, IC50 = 48.7 μM. 25198997
Bel7402 Cytotoxicity assay 96 hrs Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 2.23 μM. 25203783
HCT8 Cytotoxicity assay 96 hrs Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 3.54 μM. 25203783
C33A Cytotoxicity assay 96 hrs Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 4.61 μM. 25203783
A549 Cytotoxicity assay 96 hrs Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 6.69 μM. 25203783
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 0.01 μM. 25259515
THP1 Cytotoxicity assay 48 hrs Cytotoxicity against human THP1 cells after 48 hrs by SRB assay, IC50 = 0.04 μM. 25259515
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method, IC50 = 14.6 μM. 25261825
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells after 48 hrs by trypan blue dye exclusion method, IC50 = 15.3 μM. 25261825
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay, IC50 = 15.4 μM. 25261825
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells after 48 hrs by MTT method, IC50 = 15.6 μM. 25261825
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells after 48 hrs by MTT method, IC50 = 16.3 μM. 25261825
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells after 48 hrs by LDH release assay, IC50 = 16.8 μM. 25261825
L1210 Cytostatic activity assay 48 hrs Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting, IC50 = 0.33 μM. 25435471
HeLa Cytostatic activity assay 72 hrs Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting, IC50 = 2.6 μM. 25435471
CEM Cytostatic activity assay 72 hrs Cytostatic activity against human CEM cells after 72 hrs by Coulter counting, IC50 = 18 μM. 25435471
SMMC7721 Antiproliferative assay Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay, IC50 = 5.62 μM. 25442303
A549 Antiproliferative assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay, IC50 = 8.13 μM. 25442303
MCF7 Antiproliferative assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay, IC50 = 14.26 μM. 25442303
LoVo Antiproliferative assay 48 hrs Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 12.7 μM. 25453794
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 16.3 μM. 25453794
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 18.1 μM. 25453794
BGC823 Antiproliferative assay 48 hrs Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 35.6 μM. 25453794
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 36.2 μM. 25453794
U87 Antiproliferative assay 48 hrs Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 38.2 μM. 25453794
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 30.45 μM. 25462253
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 36.04 μM. 25462253
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 36.53 μM. 25462253
MCF7 Anticancer assay 48 hrs Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 26.9 μM. 25462264
GES-1 Cytotoxicity assay 48 hrs Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay, IC50 = 30.9 μM. 25462264
K562 Anticancer assay 48 hrs Anticancer activity against human K562 cells after 48 hrs by MTT assay, IC50 = 31.6 μM. 25462264
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay, IC50 = 6 μM. 25462277
T47D Cytotoxicity assay 72 hrs Cytotoxicity against human T47D cells after 72 hrs by SRB assay, IC50 = 7.9 μM. 25462277
HuH7 Cytotoxicity assay 72 hrs Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay, IC50 = 30.7 μM. 25462277
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay, IC50 = 34.48 μM. 25466196
SKBR3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay, IC50 = 38.88 μM. 25466196
B16 Cytotoxicity assay 48 hrs Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 7.64 μM. 25506718
MKN28 Cytotoxicity assay 48 hrs Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 9.67 μM. 25506718
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 13.45 μM. 25506718
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 9.09 μM. 25529742
SF763 Antiproliferative assay 72 hrs Antiproliferative activity against human SF763 cells after 72 hrs by MTT assay, IC50 = 9.34 μM. 25529742
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 10.45 μM. 25529742
B16 Antiproliferative assay 72 hrs Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay, IC50 = 10.52 μM. 25529742
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 11.78 μM. 25529742
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 3.71 μM. 25554922
Bcap37 Cytotoxicity assay 48 hrs Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 5.18 μM. 25554922
SGC7901 Cytotoxicity assay 48 hrs Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 6.56 μM. 25554922
BALB/3T3 Antiproliferative assay 72 hrs Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 3.23 μM. 25644674
LoVo Antiproliferative assay 72 hrs Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 4.69 μM. 25644674
doxorubicin-resistant LoVo/DX Antiproliferative assay 72 hrs Antiproliferative activity against human doxorubicin-resistant LoVo/DX cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 6 μM. 25644674
SW707 Antiproliferative assay 72 hrs Antiproliferative activity against human SW707 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 20.46 μM. 25644674
vincristine-resistant HL60/Vinc Antiproliferative assay 72 hrs Antiproliferative activity against human vincristine-resistant HL60/Vinc cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 21.15 μM. 25644674
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 22.54 μM. 25644674
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 25.08 μM. 25644674
LS180 Antiproliferative assay 72 hrs Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 38.92 μM. 25644674
B16F10 Anticancer assay 72 hrs Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 1.43 μM. 25655718
MGC803 Anticancer assay 72 hrs Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 8.43 μM. 25655718
MCF7 Anticancer assay 72 hrs Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 9.12 μM. 25655718
EC109 Anticancer assay 72 hrs Anticancer activity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 11.61 μM. 25655718
HCT8 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 0.91 μM. 25675144
HCT8 Antiproliferative assay 72 hrs Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 36.638 μM. 25675144
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 10.72 μM. 25707012
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 12.24 μM. 25707012
EC9706 Cytotoxicity assay 72 hrs Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 15.67 μM. 25707012
SMMC7721 Cytotoxicity assay 72 hrs Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 20.4 μM. 25707012
SW1573 Antiproliferative assay 48 hrs Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.3 μM. 25752525
HBL100 Antiproliferative assay 48 hrs Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.5 μM. 25752525
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay, GI50 = 15 μM. 25752525
T47D Antiproliferative assay 48 hrs Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 47 μM. 25752525
WiDr Antiproliferative assay 48 hrs Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay, GI50 = 49 μM. 25752525
MGC803 Anticancer assay 48 hrs Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 3.58 μM. 25812966
SMMC7721 Anticancer assay 48 hrs Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 4.87 μM. 25812966
HepG2 Anticancer assay 48 hrs Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 5.86 μM. 25812966
SGC7901 Anticancer assay 48 hrs Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 6.12 μM. 25812966
SKOV3 Cytotoxicity assay 2 days Cytotoxicity against human SKOV3 cells after 2 days by MTT assay, IC50 = 27.34 μM. 25841196
HepG2 Cytotoxicity assay 2 days Cytotoxicity against human HepG2 cells after 2 days by MTT assay, IC50 = 31.98 μM. 25841196
A549 Cytotoxicity assay 2 days Cytotoxicity against human A549 cells after 2 days by MTT assay, IC50 = 38.23 μM. 25841196
T24 Cytotoxicity assay 2 days Cytotoxicity against human T24 cells after 2 days by MTT assay, IC50 = 40.57 μM. 25841196
SPCA2 Cytotoxicity assay 2 days Cytotoxicity against human SPCA2 cells after 2 days by MTT assay, IC50 = 44.1 μM. 25841196
NCI-H460 Cytotoxicity assay 2 days Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay, IC50 = 46.15 μM. 25841196
MGC803 Cytotoxicity assay 2 days Cytotoxicity against human MGC803 cells after 2 days by MTT assay, IC50 = 47.39 μM. 25841196
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 29.58 μM. 25841199
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 30.79 μM. 25841199
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 36.34 μM. 25841199
T24 Cytotoxicity assay 48 hrs Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 37.56 μM. 25841199
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 40.94 μM. 25841199
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 5.82 μM. 25870131
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 6.37 μM. 25870131
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 7.51 μM. 25870131
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay, IC50 = 2.8 μM. 25919052
PANC1 Antiproliferative assay 72 hrs Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay, IC50 = 3.7 μM. 25919052
PSN1 Antiproliferative assay 72 hrs Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay, IC50 = 4.4 μM. 25919052
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay, IC50 = 5.2 μM. 25919052
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay, IC50 = 5.8 μM. 25919052
TIG3 Antiproliferative assay 72 hrs Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay, IC50 = 8.4 μM. 25919052
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 8.93 μM. 25959813
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 9.56 μM. 25959813
Bel7402 Antiproliferative assay 48 hrs Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 19.91 μM. 25959813
NIH/3T3 Antiproliferative assay 48 hrs Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 22.36 μM. 25959813
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 40.38 μM. 25959813
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 8 μM. 25969171
L1210 Cytotoxicity assay Cytotoxicity against mouse L1210 cells assessed as inhibition of cell proliferation, IC50 = 0.33 μM. 26001344
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation, IC50 = 0.54 μM. 26001344
CEM Cytotoxicity assay Cytotoxicity against human CEM cells assessed as inhibition of cell proliferation, IC50 = 18 μM. 26001344
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay, IC50 = 2.2 μM. 26222449
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay, IC50 = 4.5 μM. 26222449
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay, IC50 = 4.9 μM. 26222449
HCT8 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay, IC50 = 6.3 μM. 26227777
Bel7402 Cytotoxicity assay 72 hrs Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 10.07 μM. 26227777
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 14.15 μM. 26227777
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 16.42 μM. 26227777
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 2.13 μM. 26231080
MCF7 Anticancer assay 48 hrs Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 2.36 μM. 26231080
HeLa Anticancer assay 48 hrs Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 4.6 μM. 26231080
HaCaT Cytotoxicity assay 48 hrs Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 15.26 μM. 26231080
Hep3B Cytotoxicity assay 2 days Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 1.5 μM. 26259802
Bcap37 Cytotoxicity assay 2 days Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 5.58 μM. 26259802
MCF7 Cytotoxicity assay 2 days Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 11.5 μM. 26259802
HepG2 Cytotoxicity assay 2 days Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 40.34 μM. 26259802
A549 Cytotoxicity assay 2 days Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 44.05 μM. 26259802
SW620 Antiproliferative assay 72 hrs Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay, IC50 = 0.79 μM. 26291038
MIAPaCa2 Antiproliferative assay 72 hrs Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay, IC50 = 11.67 μM. 26291038
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 5.012 μM. 26301558
DU145 Antiproliferative assay 48 hrs Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 6.072 μM. 26301558
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 7.244 μM. 26301558
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 8.317 μM. 26301558
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 19.39 μM. 26363869
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 22.28 μM. 26363869
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by MTT assay, IC50 = 22.63 μM. 26363869
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. 26363869
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay, IC50 = 15.83 μM. 26413725
PA1 Anticancer assay 48 hrs Anticancer activity against human PA1 cells after 48 hrs by MTT assay, IC50 = 7.59 μM. 26413726
BT549 Anticancer assay 48 hrs Anticancer activity against human BT549 cells after 48 hrs by MTT assay, IC50 = 19.82 μM. 26413726
DU145 Anticancer assay 48 hrs Anticancer activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 39.17 μM. 26413726
MDA-MB-231 Anticancer assay 48 hrs Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 45.43 μM. 26413726
SH-SY5Y Antiproliferative assay 72 hrs Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control, GI50 = 1.5 μM. 26539626
Caco2 Antiproliferative assay 72 hrs Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control, GI50 = 2.2 μM. 26539626
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 6.76 μM. 26595184
SGC7901 Antiproliferative assay 72 hrs Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 11.9 μM. 26595184
MDA-MB-435S Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay, IC50 = 15.19 μM. 26595184
L02 Cytotoxicity assay 72 hrs Cytotoxicity against human L02 cells after 72 hrs by MTT assay, IC50 = 25.9 μM. 26595184
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 42.5 μM. 26595184
PANC1 Antiproliferative assay 72 hrs Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay, IC50 = 0.4 μM. 26606140
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay, IC50 = 1.1 μM. 26606140
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay, IC50 = 6.4 μM. 26606140
PSN1 Antiproliferative assay 72 hrs Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay, IC50 = 8.7 μM. 26606140
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay, IC50 = 9 μM. 26606140
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 0.09 μM. 26617970
SW620 Antiproliferative assay 72 hrs Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.79 μM. 26617970
A549 Cytotoxicity assay Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.1 μM. 26629861
Neuro2a Cytotoxicity assay Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay, IC50 = 1.2 μM. 26629861
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay, IC50 = 1.5 μM. 26629861
COLO205 Cytotoxicity assay Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. 26629861
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTS assay, IC50 = 3.52 μM. 26703795
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay, IC50 = 5.53 μM. 26703795
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay, IC50 = 24.5 μM. 26703795
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay, IC50 = 32.18 μM. 26703795
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay, IC50 = 43.71 μM. 26703795
SKOV3 Cytotoxicity assay 48 hrs Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 22.43 μM. 26706349
HCT116 Cytotoxicity assay 48 hrs Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 24.58 μM. 26706349
Bel7404 Cytotoxicity assay 48 hrs Cytotoxic activity against human Bel7404 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 30.23 μM. 26706349
A549 Cytotoxicity assay 48 hrs Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 31.33 μM. 26706349
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 35.52 μM. 26706349
MDST8 Cytotoxicity assay 72 hrs Cytotoxicity against human MDST8 cells after 72 hrs by CCK8 assay, IC50 = 0.064 μM. 26725029
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay, IC50 = 0.52 μM. 26725029
KM12 Cytotoxicity assay 48 hrs Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. 26727215
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. 26727215
HCC2998 Cytotoxicity assay 48 hrs Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. 26727215
COLO205 Cytotoxicity assay 48 hrs Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. 26727215
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. 26727215
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. 26727215
SW620 Cytotoxicity assay 48 hrs Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. 26727215
MCF7 Antiproliferative assay 96 hrs Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 0.9 μM. 26731300
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 4.9 μM. 26731300
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 5.3 μM. 26731300
T84 Antiproliferative assay 96 hrs Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 6.2 μM. 26731300
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 1.44 μM. 26735909
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.47 μM. 26735909
U87MG Cytotoxicity assay 72 hrs Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.61 μM. 26735909
L929 Antiproliferative assay 48 hrs Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay, IC50 = 2.98 μM. 26786698
SMMC7721 Antiproliferative assay 48 hrs Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay, IC50 = 5.62 μM. 26786698
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay, IC50 = 8.13 μM. 26786698
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay, IC50 = 17.21 μM. 26786698
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 1.4 μM. 26854375
THP1 Cytotoxicity assay 48 hrs Cytotoxicity against human THP1 cells after 48 hrs by MTT assay, IC50 = 1.7 μM. 26854375
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 2 μM. 26854375
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 2.3 μM. 26854375
HCT8 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 32.31 μM. 26873416
WI38 Cytotoxicity assay 48 hrs Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 38.91 μM. 26873416
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 41.62 μM. 26873416
Hep3B Cytotoxicity assay 48 hrs Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay, IC50 = 10.53 μM. 26883148
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 34.27 μM. 26883148
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 42.78 μM. 26883148
Bcap37 Cytotoxicity assay 48 hrs Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 47.09 μM. 26883148
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 49.72 μM. 26883148
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 26.14 μM. 26922223
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 26.18 μM. 26922223
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 27.43 μM. 26922223
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 38.3 μM. 26922223
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 49.02 μM. 26922223
HT-29 Anticancer assay 72 hrs Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay, IC50 = 6.3 μM. 26922233
RKO Anticancer assay 72 hrs Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay, IC50 = 6.8 μM. 26922233
HT-29 Anticancer assay 48 hrs Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 25 μM. 26922233
HCT116 Anticancer assay 72 hrs Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay, IC50 = 27.8 μM. 26922233
RKO Anticancer assay 48 hrs Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 41.1 μM. 26922233
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 4.84 μM. 27073055
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by SRB assay, IC50 = 6.23 μM. 27073055
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7cells after 72 hrs by SRB assay, IC50 = 6.53 μM. 27073055
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay, IC50 = 6.6 μM. 27073055
HDF Cytotoxicity assay 72 hrs Cytotoxicity against HDF cells after 72 hrs by SRB assay, IC50 = 7.02 μM. 27073055
143B Cytotoxicity assay 72 hrs Cytotoxicity against human 143B cells after 72 hrs by SRB assay, IC50 = 13.01 μM. 27073055
thymidine kinase deficient 143B Cytotoxicity assay 72 hrs Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay, IC50 = 16.31 μM. 27073055
U87MG Cytotoxicity assay 72 hrs Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method, IC50 = 18.25 μM. 27081742
PC3 Antiproliferative assay 48 hrs Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 2.76 μM. 27092413
HT-29 Antiproliferative assay 48 hrs Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 2.8 μM. 27092413
U87MG Antiproliferative assay 48 hrs Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay, IC50 = 3.65 μM. 27092413
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.98 μM. 27092413
HaCaT Antiproliferative assay 48 hrs Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay, IC50 = 16.15 μM. 27092413
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 1.25 μM. 27105028
EC109 Antiproliferative assay 72 hrs Antiproliferative activity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 3.17 μM. 27105028
SH-SY5Y Antiproliferative assay 72 hrs Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 3.26 μM. 27105028
U87 Antiproliferative assay 72 hrs Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 5.61 μM. 27105028
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 7.61 μM. 27105028
MDA-MB-231 Antiproliferative assay 48 hrs Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 24.6 μM. 27128180
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 30.41 μM. 27128180
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.41 μM. 27128180
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. 27128180
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 13.5 μM. 27133593
Bcap37 Cytotoxicity assay 48 hrs Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 15.47 μM. 27133593
Hep3B Cytotoxicity assay 48 hrs Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay, IC50 = 17.53 μM. 27133593
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 21.58 μM. 27133593
U251 Cytotoxicity assay 48 hrs Cytotoxicity against human U251 cells after 48 hrs by MTT assay, IC50 = 24.69 μM. 27133593
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 25.17 μM. 27133593
LNCAP Cytotoxicity assay 24 hrs Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay, IC50 = 0.03 μM. 27156770
PC3 Cytotoxicity assay 24 hrs Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay, IC50 = 0.03 μM. 27156770
Bcap37 Cytotoxicity assay 48 hrs Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 5.18 μM. 27189676
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 11.5 μM. 27189676
Hep3B Cytotoxicity assay 48 hrs Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 22.99 μM. 27189676
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 40.34 μM. 27189676
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 44.05 μM. 27189676
PA1 Cytotoxicity assay 48 hrs Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 8.51 μM. 27210438
U87MG Cytotoxicity assay 48 hrs Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 15.48 μM. 27210438
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 32.27 μM. 27210438
LNCAP Cytotoxicity assay 48 hrs Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 47.18 μM. 27210438
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis, IC50 = 11.1 μM. 27234893
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay, IC50 = 46.83 μM. 27287368
A375-S2 Antiproliferative assay 48 hrs Antiproliferative activity against human A375-S2 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 1.91 μM. 27295506
ACHN Antiproliferative assay 48 hrs Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 2.73 μM. 27295506
22Rv1 Antiproliferative assay 48 hrs Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 3.83 μM. 27295506
C4-2B Antiproliferative assay 48 hrs Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 5.64 μM. 27295506
A498 Antiproliferative assay 48 hrs Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 8.83 μM. 27295506
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay, IC50 = 2.8 μM. 27311895
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay, IC50 = 5.2 μM. 27311895
HeLa Antiproliferative assay 72 hrs Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay, IC50 = 5.8 μM. 27311895
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 3 μM. 27343853
WI38 Cytotoxicity assay 48 hrs Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 4 μM. 27343853
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 8 μM. 27343853
UO31 Cytotoxicity assay 48 hrs Cytotoxicity against human UO31 cells measured after 48 hrs by SRB assay, GI50 = 6.76083 μM. 27391135
U251 Cytotoxicity assay 48 hrs Cytotoxicity against human U251 cells measured after 48 hrs by SRB assay, GI50 = 42.6579 μM. 27391135
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 15.38 μM. 27448774
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 35.91 μM. 27448774
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 39.86 μM. 27448774
Caco2 Growth inhibition assay 72 hrs Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay, GI50 = 3.3 μM. 27504537
MCF7 Growth inhibition assay 72 hrs Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay, GI50 = 3.6 μM. 27504537
PC3 Growth inhibition assay 72 hrs Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay, GI50 = 4.1 μM. 27504537
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay, IC50 = 6.8 μM. 27537924
SGC7901 Cytotoxicity assay 72 hrs Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay, IC50 = 11.9 μM. 27537924
MDA-MB-435S Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay, IC50 = 15.2 μM. 27537924
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay, IC50 = 42.5 μM. 27537924
colon cancer cell Growth inhibition assay 48 hrs Growth inhibition of human colon cancer cells after 48 hrs by SRB assay, GI50 = 8.4 μM. 27554444
leukemia cell Growth inhibition assay 48 hrs Growth inhibition of human leukemia cells after 48 hrs by SRB assay, GI50 = 15.1 μM. 27554444
prostate cancer cell Growth inhibition assay 48 hrs Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay, GI50 = 22.7 μM. 27554444
renal cancer cell Growth inhibition assay 48 hrs Growth inhibition of human renal cancer cells after 48 hrs by SRB assay, GI50 = 45.6 μM. 27554444
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 26.1 μM. 27561718
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 28.2 μM. 27561718
IOSE-144 Cytotoxicity assay 48 hrs Cytotoxicity against human IOSE-144 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 36.1 μM. 27561718
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.3 μM. 27561719
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.6 μM. 27561719
MDA-MB-231 Cytotoxicity assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. 27561719
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay, IC50 = 1.9 μM. 27561719
SW780 Cytotoxicity assay 72 hrs Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 6.99 μM. 27597411
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 10.64 μM. 27597411
HL-7702 Cytotoxicity assay 72 hrs Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 12.85 μM. 27597411
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 13.19 μM. 27597411
GES-1 Cytotoxicity assay 72 hrs Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 13.75 μM. 27597411
TE1 Cytotoxicity assay 72 hrs Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 17.32 μM. 27597411
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 30.47 μM. 27614408
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 35.98 μM. 27614408
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 40.58 μM. 27614408
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 45.32 μM. 27614408
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay, GI50 = 4.5 μM. 27688184
HepG2 Function assay 48 hrs Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay, GI50 = 7 μM. 27688184
U87 Function assay 48 hrs Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay, GI50 = 13 μM. 27688184
HCT116 Growth inhibition assay 72 hrs Growth inhibition of human HCT116 cells after 72 hrs by MTS assay, IC50 = 2.5 μM. 27704811
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay, IC50 = 1.6 μM. 27720296
PC3 Cytotoxicity assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. 27720296
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. 27720296
MDA-MB-231 Cytotoxicity assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.9 μM. 27720296
L1210 Antiproliferative assay 48 hrs Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method, IC50 = 0.33 μM. 27750154
HeLa Antiproliferative assay 4 days Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method, IC50 = 0.54 μM. 27750154
CEM Antiproliferative assay 72 hrs Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method, IC50 = 18 μM. 27750154
PC9 Cytotoxicity assay Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay, IC50 = 1.99 μM. 27769034
MGC803 Cytotoxicity assay Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay, IC50 = 10.14 μM. 27769034
A549 Cytotoxicity assay Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay, IC50 = 13.95 μM. 27769034
EC109 Cytotoxicity assay Cytotoxicity against human EC109 cells assessed as growth inhibition by MTT assay, IC50 = 25.99 μM. 27769034
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 7.35 μM. 27771599
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 9.25 μM. 27771599
EC109 Antiproliferative assay 72 hrs Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay, IC50 = 10.59 μM. 27771599
HUCCA Cytotoxicity assay 24 hrs Cytotoxicity against HUCCA cells assessed as decrease in cell viability after 24 hrs by MTT assay, IC50 = 13.4 μM. 27825763
QBC939 Cytotoxicity assay 24 hrs Cytotoxicity against human QBC939 cells assessed as decrease in cell viability after 24 hrs by MTT assay, IC50 = 16.1 μM. 27825763
SW620 Antiproliferative assay 72 hrs Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.08 μM. 27875779
CFPAC-1 Antiproliferative assay 72 hrs Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay, IC50 = 0.14 μM. 27875779
WI38 Antiproliferative assay 72 hrs Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 0.94 μM. 27875779
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. 27875779
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 8.81 μM. 27875779
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 8.9 μM. 27875779
Hep3B Cytotoxicity assay Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay, IC50 = 9.36 μM. 27913179
A549 Cytotoxicity assay Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay, IC50 = 16.63 μM. 27913179
WISH Cytotoxicity assay 24 hrs Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 7.1 μM. 27951487
WI38 Cytotoxicity assay 24 hrs Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 9.3 μM. 27951487
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 1.16 μM. 27987485
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 5 μM. 27987485
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 5 μM. 27987485
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.12 μM. 27987485
Hep3B Cytotoxicity assay 48 hrs Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 10.53 μM. 27993516
HepG2 Cytotoxicity assay 48 hrs Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 32.6 μM. 27993516
HepG2 Growth inhibition assay 24 hrs Growth inhibition of human HepG2 cells after 24 hrs by MTT assay, IC50 = 32.87 μM. 28011220
PA1 Growth inhibition assay 24 hrs Growth inhibition of human PA1 cells after 24 hrs by MTT assay, IC50 = 39.5 μM. 28011220
HCT15 Growth inhibition assay 24 hrs Growth inhibition of human HCT15 cells after 24 hrs by MTT assay, IC50 = 45.01 μM. 28011220
PC3 Cytotoxicity assay 72 hrs Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 15.31 μM. 28011223
SKOV3 Cytotoxicity assay 72 hrs Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 23.11 μM. 28011223
A549 Cytotoxicity assay 72 hrs Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 32.15 μM. 28011223
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 10.17 μM. 28038327
Hep3B Cytotoxicity assay 48 hrs Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 10.53 μM. 28038327
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 34.27 μM. 28038327
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 42.78 μM. 28038327
Bcap37 Cytotoxicity assay 48 hrs Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 47.1 μM. 28038327
U251 Cytotoxicity assay 48 hrs Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 48.68 μM. 28038327
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 7.21 μM. 28038329
EC109 Cytotoxicity assay 48 hrs Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 10.3 μM. 28038329
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 29.31 μM. 28038329
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 10.5 μM. 28073676
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 19.2 μM. 28073676
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 29.2 μM. 28073676
BGC823 Antiproliferative assay 48 hrs Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 34.8 μM. 28073676
IOSE-144 Antiproliferative assay 48 hrs Antiproliferative activity against human IOSE-144 cells after 48 hrs by MTT assay, IC50 = 38.1 μM. 28073676
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 26.14 μM. 28110871
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 38.3 μM. 28110871
PANC1 Antiproliferative assay 48 hrs Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay, IC50 = 47.83 μM. 28110871
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 49.02 μM. 28110871
BCG823 Cytotoxicity assay 48 hrs Cytotoxicity against human BCG823 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 10.1 μM. 28117202
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 16.1 μM. 28117202
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 17.2 μM. 28117202
EC9706 Antiproliferative assay 48 hrs Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay, IC50 = 23.26 μM. 28119200
ECA109 Antiproliferative assay 48 hrs Antiproliferative activity against human ECA109 cells after 48 hrs by MTT assay, IC50 = 30.25 μM. 28119200
K562 Growth inhibition assay 48 hrs Growth inhibition of human K562 cells after 48 hrs by WST1 assay, IC50 = 38.58 μM. 28126436
KKU-M214 Cytotoxicity assay 72 hrs Cytotoxicity against human KKU-M214 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 3.76 μM. 28140592
HL60 Antiproliferative assay 48 hrs Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay, IC50 = 1.62 μM. 28152430
NCI-H1299 Antiproliferative assay 48 hrs Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay, IC50 = 8.91 μM. 28152430
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1.75 μM. 28165738
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 2.25 μM. 28165738
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 3.12 μM. 28165738
K562 Antiproliferative assay 72 hrs Antiproliferative activity against human K562 cells after 72 hrs by MTT assay, IC50 = 3.54 μM. 28165738
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 10.53 μM. 28174107
Hep3B Cytotoxicity assay 48 hrs Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 49.72 μM. 28174107
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.4 μM. 28219046
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 18.4 μM. 28219046
HuH7 Cytotoxicity assay 72 hrs Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 21 μM. 28219046
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 1.2 μM. 28254697
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.4 μM. 28254697
HepG2 Cytotoxicity assay 24 hrs Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay, IC50 = 1.4 μM. 28254697
COLO205 Cytotoxicity assay 24 hrs Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay, IC50 = 1.9 μM. 28254697
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 2.1 μM. 28262527
Hep3B Cytotoxicity assay Cytotoxicity against human Hep3B cells by MTT assay, IC50 = 2.66 μM. 28262527
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay, IC50 = 5.94 μM. 28301815
LO2 Antiproliferative assay 72 hrs Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay, IC50 = 32.546 μM. 28301815
HCT116 Cytotoxicity assay Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay, IC50 = 41 μM. 28334654
MCF7 Cytotoxicity assay Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay, IC50 = 41.5 μM. 28334654
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 9.02 μM. 28363444
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 13.31 μM. 28363444
BGC823 Antiproliferative assay 48 hrs Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 17.37 μM. 28363444
SW1116 Antiproliferative assay 48 hrs Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay, IC50 = 18.52 μM. 28363444
Hep3B Cytotoxicity assay Cytotoxicity against human Hep3B cells by MTT assay, IC50 = 11.9 μM. 28371676
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 30 μM. 28371676
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 32.6 μM. 28371676
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 38.2 μM. 28371676
MCF7 Antiproliferative assay 48 to 72 hrs Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 7.67 μM. 28395218
A549 Antiproliferative assay 48 to 72 hrs Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 10.65 μM. 28395218
SGC7901 Antiproliferative assay 48 to 72 hrs Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 13.25 μM. 28395218
HepG2 Antiproliferative assay 48 to 72 hrs Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 17.44 μM. 28395218
PC3 Antiproliferative assay 48 to 72 hrs Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 38.61 μM. 28395218
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, GI50 = 1.67 μM. 28400235
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by SRB assay, GI50 = 2.09 μM. 28400235
DU145 Growth inhibition assay 48 hrs Growth inhibition of human DU145 cells after 48 hrs by SRB assay, GI50 = 5.82 μM. 28400235
T47D Antiproliferative assay 48 hrs Antiproliferative activity against human T47D cells after 48 hrs by MTT assay, IC50 = 12.1 μM. 28400238
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 15.1 μM. 28400238
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 20.1 μM. 28400238
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 26.2 μM. 28400238
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells, IC50 = 7.9 μM. 28431341
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells, IC50 = 8.1 μM. 28431341
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells, IC50 = 9.9 μM. 28431341
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by MTT assay, IC50 = 1.2 μM. 28431881
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 1.6 μM. 28431881
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 1.86 μM. 28431881
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 2.18 μM. 28431881
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 4.33 μM. 28431881
HGC27 Cytotoxicity assay 48 hrs Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay, IC50 = 14.72 μM. 28431881
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 6.56 μM. 28456031
HGC27 Antiproliferative assay 72 hrs Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay, IC50 = 8.22 μM. 28456031
NCI-H1650 Antiproliferative assay 72 hrs Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay, IC50 = 12.52 μM. 28456031
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 4.16 μM. 28458133
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 24.33 μM. 28458133
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 28.73 μM. 28458133
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 29.07 μM. 28458133
Caco2 Cytotoxicity assay 24 hrs Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay, IC50 = 31 μM. 28463785
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay, IC50 = 13.9 μM. 28488862
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay, IC50 = 4.9 μM. 28494251
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 24.3 μM. 28494251
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 29.1 μM. 28494251
SW620 Antiproliferative assay 72 hrs Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.08 μM. 28525845
CFPAC-1 Antiproliferative assay 72 hrs Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay, IC50 = 0.14 μM. 28525845
WI38 Cytotoxicity assay 72 hrs Cytotoxicity against human WI38 cells after 72 hrs by MTT assay, IC50 = 0.94 μM. 28525845
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 8.81 μM. 28525845
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 8.9 μM. 28525845
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 41.9 μM. 28532669
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 4.7 μM. 28558970
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 5.3 μM. 28558970
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 5.6 μM. 28558970
WI38 Cytotoxicity assay 72 hrs Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 6.8 μM. 28558970
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 4 μM. 28623814
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 4.3 μM. 28623814
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 5.3 μM. 28623814
W138 Cytotoxicity assay 48 hrs Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 5.73 μM. 28623814
P388 Cytotoxicity assay 72 hrs Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay, IC50 = 5.8 μM. 28648460
MOLT4 Cytotoxicity assay 72 hrs Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay, IC50 = 6.2 μM. 28648460
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay, IC50 = 7.2 μM. 28648460
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay, IC50 = 30.5 μM. 28648460
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 3.18 μM. 28666860
LNCAP Antiproliferative assay 48 hrs Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay, IC50 = 5.21 μM. 28666860
PC3 Cytotoxicity assay Cytotoxic activity against human PC3 cells, IC50 = 1.6 μM. 28697923
HL60 Cytotoxicity assay Cytotoxic activity against human HL60 cells, IC50 = 2.8 μM. 28697923
HCT116 Cytotoxicity assay Cytotoxic activity against human HCT116 cells, IC50 = 17.01 μM. 28697923
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.47 μM. 28716495
CRL1790 Cytotoxicity assay 48 hrs Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay, GI50 = 10.3 μM. 28716495
SW1573 Antiproliferative assay 48 hrs Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay, GI50 = 4.3 μM. 28728108
HBL100 Antiproliferative assay 48 hrs Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay, GI50 = 5.5 μM. 28728108
hTERT-BJ Antiproliferative assay 48 hrs Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay, GI50 = 5.5 μM. 28728108
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, GI50 = 15 μM. 28728108
T47D Antiproliferative assay 48 hrs Antiproliferative activity against human T47D cells after 48 hrs by SRB assay, GI50 = 47 μM. 28728108
WiDr Antiproliferative assay 48 hrs Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay, GI50 = 49 μM. 28728108
A549 Cytotoxicity assay 48 hrs Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 34.47 μM. 28754470
T24 Cytotoxicity assay 48 hrs Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 40.14 μM. 28754470
SPCA2 Cytotoxicity assay 48 hrs Cytotoxicity in human SPCA2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 44.34 μM. 28754470
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 28.8 μM. 28756264
SKOV3 Antiproliferative assay 48 hrs Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 32.5 μM. 28756264
NCI-H460 Antiproliferative assay 48 hrs Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 36 μM. 28756264
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 38.5 μM. 28756264
HL-7702 Cytotoxicity assay 48 hrs Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay, IC50 = 46 μM. 28756264
EC109 Antiproliferative assay 72 hrs Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay, IC50 = 5.01 μM. 28759876
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 6.89 μM. 28759876
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.21 μM. 28759876
GES-1 Cytotoxicity assay 72 hrs Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 8.59 μM. 28759876
HGC27 Antiproliferative assay 72 hrs Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay, IC50 = 11.02 μM. 28759876
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 5.2 μM. 28759877
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 13.7 μM. 28759877
SKOV3 Cytotoxicity assay 72 hrs Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 20.8 μM. 28759877
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 24.5 μM. 28759877
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 9.79 μM. 28763643
PC3 Antiproliferative assay 48 hrs Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 12.87 μM. 28763643
SH-SY5Y Antiproliferative assay 48 hrs Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay, GI50 = 12 μM. 28763647
K562 Antiproliferative assay 48 hrs Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, GI50 = 19 μM. 28763647
AGS Antiproliferative assay 48 hrs Antiproliferative activity against human AGS cells after 48 hrs by MTT assay, GI50 = 25 μM. 28763647
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 2.9 μM. 28838694
EC109 Antiproliferative assay 48 hrs Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay, IC50 = 6.21 μM. 28838695
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 7.52 μM. 28838695
MKN45 Antiproliferative assay 48 hrs Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay, IC50 = 8.89 μM. 28838695
NCI-H1650 Antiproliferative assay 48 hrs Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay, IC50 = 14.25 μM. 28838695
EC109 Antiproliferative assay 48 hrs Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay, IC50 = 6.21 μM. 28863355
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 7.52 μM. 28863355
MKN45 Antiproliferative assay 48 hrs Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay, IC50 = 8.89 μM. 28863355
GES-1 Antiproliferative assay 48 hrs Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay, IC50 = 9.02 μM. 28863355
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 12.92 μM. 28863355
NCI-H1650 Antiproliferative assay 48 hrs Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay, IC50 = 14.25 μM. 28863355
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by SRB assay, GI50 = 4.2 μM. 28898082
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by SRB assay, GI50 = 11.7 μM. 28898082
PC3 Cytotoxicity assay 48 hrs Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay, IC50 = 1.2 μM. 28923381
DU145 Cytotoxicity assay 48 hrs Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay, IC50 = 2.18 μM. 28923381
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay, IC50 = 8.62 μM. 28923381
HT-29 Antitumor assay 48 hrs Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 4.6 μM. 28926764
MCF7 Antitumor assay 48 hrs Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 5.7 μM. 28926764
WI38 Cytotoxicity assay 48 hrs Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 5.7 μM. 28926764
HepG2 Antitumor assay 48 hrs Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 6.9 μM. 28926764
L02 Antiproliferative assay 48 hrs Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay, IC50 = 19.1 μM. 28947149
AGS Antiproliferative assay 48 hrs Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay, IC50 = 29.6 μM. 28947149
B16 Cytotoxicity assay 72 hrs Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 1.19 μM. 28987604
A549 Cytotoxicity assay 72 hrs Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 8.9 μM. 28987604
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 10.4 μM. 28987604
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 14.7 μM. 28987604
HL60 Antiproliferative assay 24 hrs Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 3.69 μM. 29037951
THP1 Antiproliferative assay 24 hrs Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 4.87 μM. 29037951
PC3 Antiproliferative assay 24 hrs Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 23.94 μM. 29037951
HepG2 Antiproliferative assay 24 hrs Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 30.48 μM. 29037951
SH-SY5Y Antiproliferative assay 48 hrs Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay, GI50 = 11.9 μM. 29040954
K562 Antiproliferative assay 48 hrs Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, GI50 = 18.5 μM. 29040954
AGS Antiproliferative assay 48 hrs Antiproliferative activity against human AGS cells after 48 hrs by MTT assay, GI50 = 24.6 μM. 29040954
EC109 Antiproliferative assay 48 hrs Antiproliferative activity against human EC109 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 6.21 μM. 29113745
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 7.52 μM. 29113745
MKN45 Antiproliferative assay 48 hrs Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 8.89 μM. 29113745
NCI-H1650 Antiproliferative assay 48 hrs Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 14.25 μM. 29113745
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method, IC50 = 2.8 μM. 29131616
PC3 Antiproliferative assay Antiproliferative activity against human PC3 cells by MTT assay, IC50 = 22.02 μM. 29131616
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 9.2 μM. 29133037
EAC Cytotoxicity assay 48 hrs Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 9.6 μM. 29133037
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 10.2 μM. 29133037
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 10.6 μM. 29133037
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 10.6 μM. 29133037
DLA Cytotoxicity assay 48 hrs Cytotoxicity against mouse DLA cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 10.8 μM. 29133037
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 11.2 μM. 29133037
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 11.4 μM. 29133037
MDA-MB-468 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 44.6 μM. 29133037
MDA-MB-468 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 44.9 μM. 29133037
SW620 Antiproliferative assay 72 hrs Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.08 μM. 29133046
CFPAC-1 Antiproliferative assay 72 hrs Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay, IC50 = 0.14 μM. 29133046
WI38 Antiproliferative assay 72 hrs Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 0.94 μM. 29133046
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. 29133046
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 8.81 μM. 29133046
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 9.49 μM. 29133049
WM9 Cytotoxicity assay 48 hrs Cytotoxicity against human WM9 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 15.8 μM. 29133049
HEL Cytotoxicity assay 48 hrs Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 15.98 μM. 29133049
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 17.74 μM. 29133049
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 19.87 μM. 29133049
PC3 Antiproliferative assay 48 hrs Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 4.75 μM. 29133051
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 8.48 μM. 29133051
SGC7901 Antiproliferative assay 48 hrs Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 10.98 μM. 29133051
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 14.15 μM. 29133051
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 8.3 μM. 29133061
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay, IC50 = 7.53 μM. 29174813
Bel7402 Cytotoxicity assay 48 hrs Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay, IC50 = 20.93 μM. 29174813
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 28.97 μM. 29174813
U937 Antiproliferative assay 48 hrs Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 9.56 μM. 29202398
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 14.52 μM. 29202398
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 15.93 μM. 29202398
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 17.02 μM. 29202398
H7402 Antiproliferative assay 48 hrs Antiproliferative activity against human H7402 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 17.58 μM. 29202398
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 18.35 μM. 29202398
H7402 Antiproliferative assay 48 hrs Antiproliferative activity against human H7402 cells after 48 hrs by MTT assay, IC50 = 21.87 μM. 29202398
PLC/PRF/5 Antiproliferative assay 48 hrs Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 22.81 μM. 29202398
U937 Antiproliferative assay 48 hrs Antiproliferative activity against human U937 cells after 48 hrs by MTT assay, IC50 = 28.76 μM. 29202398
PLC/PRF/5 Antiproliferative assay 48 hrs Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay, IC50 = 35.66 μM. 29202398
ES2 Antiproliferative assay 48 hrs Antiproliferative activity against human ES2 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 37.05 μM. 29202398
U266 Antiproliferative assay 48 hrs Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 43.48 μM. 29202398
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 44.06 μM. 29202398
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 2.35 μM. 29223098
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 8.638 μM. 29223717
143B Antiproliferative assay 48 hrs Antiproliferative activity against human 143B cells after 48 hrs by MTT assay, IC50 = 25.216 μM. 29223717
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 32.626 μM. 29223717
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 29.5 μM. 29232583
SGC7901 Antiproliferative assay 72 hrs Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 34.4 μM. 29232583
SMMC7721 Antiproliferative assay 72 hrs Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 37.8 μM. 29232583
HuH7 Antiproliferative assay 72 hrs Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay, IC50 = 5.63 μM. 29316536
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 11.29 μM. 29316536
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 25.54 μM. 29316536
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 7.86 μM. 29407946
NCI-H1650 Antiproliferative assay 72 hrs Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay, IC50 = 14.63 μM. 29407946
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 27.61 μM. 29407946
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 2.37 μM. 29407983
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.49 μM. 29407983
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 23.86 μM. 29407983
EC9706 Antiproliferative assay 72 hrs Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 5.13 μM. 29475156
EC109 Antiproliferative assay 72 hrs Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay, IC50 = 6.02 μM. 29475156
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 6.27 μM. 29475156
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 9.24 μM. 29475156
SMMC7721 Antiproliferative assay 72 hrs Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 13.7 μM. 29475156
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 18.75 μM. 29475156
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15.78 μM. 29486954
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 17.25 μM. 29486954
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 19.52 μM. 29486954
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 23.6 μM. 29486954
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay, IC50 = 28 μM. 29489361
A549 Cytotoxicity assay Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay, IC50 = 36.8 μM. 29489361
QSG7701 Antiproliferative assay 24 hrs Antiproliferative activity against human QSG7701 cells after 24 hrs by CCK-8 assay, IC50 = 6.92 μM. 29499490
SMMC7721 Antiproliferative assay 24 hrs Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay, IC50 = 12.47 μM. 29499490
QGY7703 Antiproliferative assay 24 hrs Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay, IC50 = 14.2 μM. 29499490
HepG2 Antiproliferative assay 24 hrs Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay, IC50 = 15.74 μM. 29499490
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 2.37 μM. 29524728
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.49 μM. 29524728
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 23.86 μM. 29524728
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 8.66 μM. 29635165
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 12.33 μM. 29635165
GES-1 Antiproliferative assay 72 hrs Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay, IC50 = 12.51 μM. 29635165
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 13.18 μM. 29635165
TE1 Antiproliferative assay 72 hrs Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay, IC50 = 16.53 μM. 29635165
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 3.46 μM. 29635169
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.97 μM. 29635169
SGC7901 Antiproliferative assay 72 hrs Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 19.84 μM. 29635169
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 26.91 μM. 29635169
Caco2 Antiproliferative assay 72 hrs Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay, IC50 = 38.77 μM. 29635169
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 16.7 μM. 29657100
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 35.91 μM. 29657100
DU145 Cytotoxicity assay 48 hrs Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 39.17 μM. 29657100
A549 Cytotoxicity assay 48 hrs Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 39.86 μM. 29657100
HepG2 Cytotoxicity assay 6 days Cytotoxicity against human HepG2 cells after 6 days by MTT assay, IC50 = 12 μM. 29786436
SGC7901 Cytotoxicity assay 6 days Cytotoxicity against human SGC7901 cells after 6 days by MTT assay, IC50 = 12 μM. 29786436
HepG2 Antiproliferative assay Antiproliferative activity against human HepG2 cells by MTT assay, IC50 = 1.7 μM. 29798826
HeLa Antiproliferative assay Antiproliferative activity against human HeLa cells by MTT assay, IC50 = 1.8 μM. 29798826
MCF7 Antiproliferative assay Antiproliferative activity against human MCF7 cells by MTT assay, IC50 = 1.8 μM. 29798826
COLO205 Antiproliferative assay Antiproliferative activity against human COLO205 cells by MTT assay, IC50 = 1.9 μM. 29798826
HEK293 Antiproliferative assay Antiproliferative activity against human HEK293 cells by MTT assay, IC50 = 19.6 μM. 29798826
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTS assay, IC50 = 3.52 μM. 29843103
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells by MTS assay, IC50 = 5.53 μM. 29843103
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 7 μM. 29908443
McCoy Cytotoxicity assay 72 hrs Cytotoxicity against mouse McCoy cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 15.7 μM. 29908443
PC3 Antiproliferative assay 48 hrs Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 8.45 μM. 29958763
HT-29 Antiproliferative assay 48 hrs Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 22.23 μM. 29958763
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 30.21 μM. 30007564
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 36.62 μM. 30007564
2008 Cytotoxicity assay Cytotoxicity against human 2008 cells, IC50 = 6 μM. 30035541
IGROV1 Cytotoxicity assay 72 hrs Cytotoxicity against human IGROV1 cells after 72 hrs, IC50 = 10.6 μM. 30035541
C13 Cytotoxicity assay 72 hrs Cytotoxicity against human C13 cells after 72 hrs, IC50 = 12.1 μM. 30035541
HCT8 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay, IC50 = 28.9 μM. 30037494
DLD1 Antiproliferative assay 72 hrs Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay, IC50 = 33 μM. 30037494
CCD-841-CoN Antiproliferative assay 72 hrs Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay, IC50 = 35.7 μM. 30037494
SKOV3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 26.34 μM. 30092368
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 31.98 μM. 30092368
Bel7404 Cytotoxicity assay 48 hrs Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay, IC50 = 40.21 μM. 30092368
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 45.44 μM. 30092368
RKO Growth inhibition assay 48 hrs Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay, IC50 = 10.2 μM. 30106289
LoVo Growth inhibition assay 48 hrs Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay, IC50 = 11.5 μM. 30106289
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 26.14 μM. 30142612
MGC803 Antiproliferative assay 72 hrs Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 31.04 μM. 30142612
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 38.3 μM. 30142612
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 47.97 μM. 30142612
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.05 μM. 30243153
Bel7402 Antiproliferative assay 72 hrs Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.65 μM. 30243153
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 27.89 μM. 30243153
T84 Antiproliferative assay 3 days Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay, IC50 = 3.4 μM. 30248657
A549 Antiproliferative assay 3 days Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay, IC50 = 7.1 μM. 30248657
MCF7 Antiproliferative assay 3 days Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay, IC50 = 7.8 μM. 30248657
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 4.3 μM. 30318440
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 10.75 μM. 30318440
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 11.56 μM. 30318440
NCI-H460 Cytotoxicity assay 72 hrs Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 11.75 μM. 30318440
HCT15 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay, IC50 = 11.87 μM. 30318440
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 21.05 μM. 30318440
Click to View More Cell Line Experimental Data

Biological Activity

Description 5-FU (5-Fluorouracil) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.
Targets
Thymidylate synthase [1]
(Tumor cells)
In vitro
In vitro Adrucil is an analogue of uracil with a fluorine atom at the C-5 position in place of hydrogen. It rapidly enters the cell using the same facilitated transport mechanism as uracil. Adrucil is converted intracellularly to several active metabolites: fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine triphosphate (FUTP). The Adrucil metabolite FdUMP binds to the nucleotide-binding site of TS, forming a stable ternary complex with the enzyme and CH2THF, thereby blocking binding of the normal substrate dUMP and inhibiting dTMP synthesis. Metabolite of Adrucil also can be misincorporated into DNA, leading to DNA strand breaks and cell death. The pro-apoptosis effects of Adrucil may be related to its activation of tumor suppressor p53. Loss of p53 function reduces cellular sensitivity to Adrucil. [1] Adrucil is able to inhibit the survival and induce apoptosis of a board range of cancer cells. Adrucil suppresses viabilities of the nasopharyngeal carcinoma cell line CNE2 and HONE1 [2], pancreatic cancer cell lines Capan-1 [3], and human colon carcinoma cell line HT-29 [4] with IC50 of 9 μg/mL, 3 μg/mL, 0.22 μM, 2.5 μM, respectively.
Cell Research Cell lines Human colon carcinoma cell line HT-29
Concentrations ~25 μM
Incubation Time 7 days
Method Growth inhibition is measured after treatment of cells with Adrucil for 7 days in 96-well plates (4000 HT-29 cells/well in RPMI 1640 medium with 10% dialyzed fetal bovine serum); increasing concentrations of Adrucil are added after allowing for cell attachment overnight. At the end of incubation, cells are rinsed three times with phosphate-buffered saline (pH 7.4), fixed with 10% trichloroacetic acid for 60 min at 4 ℃, washed five times with deionized water, and stained with 0.4% sulforhoda-mine B solution for 15 min at room temperature. Unstained sulforhodamine B is removed by rinsing with 1% glacial acetic acid. Afterwards, stained cell proteins are dried and dissolved with 10 mM Tris-HCl. The optical density value is measured using a detector at 540 nm wavelength.
Experimental Result Images Methods Biomarkers Images PMID
Western blot p53 / PUMA / c-PARP 25965911
Immunofluorescence non-phospho β-catenin β-catenin Sox2 / Oct4 / Nanog / ABCG2 p65 / p-p65(Ser536) / p53 / p-p53(Ser15) phospho-histone H3 caveolin-3 28588704
Growth inhibition assay Cell proliferation Cell viability 30250641
In Vivo
In vivo Adrucil is widely used in the treatment of a range of cancers, including colorectal and breast cancers. [1] 100mg/kg Adrucil significantly suppresses tumor growth of murine colon carcinomas Colon 38 with tumor-doubling time (TD), growth-delay factor (GDF), and T/C of 26.5 days, 4.4, and 14%. [5]
Animal Research Animal Models Murine colon carcinomas Colon 38
Dosages 100 mg/kg
Administration i.p. weekly
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05780684 Recruiting Colorectal Cancer|Esophagus Cancer|Appendix Cancer|Small Bowel Cancer|Ampullary Cancer Dartmouth-Hitchcock Medical Center July 14 2023 Not Applicable
NCT05362955 Recruiting CIN 2/3|HIV Infections UNC Lineberger Comprehensive Cancer Center April 26 2023 Phase 1
NCT05620524 Recruiting TDM of 5-FU|Pharmacokinetic Observational Study Catharina Ziekenhuis Eindhoven December 19 2022 --
NCT05505539 Withdrawn Oral Leukoplakia University of California San Francisco September 30 2022 Phase 1
NCT05444673 Recruiting Temporal Bone Squamous Cell Carcinoma Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University June 1 2022 Phase 4

Chemical lnformation & Solubility

Molecular Weight 130.08 Formula

C4H3FN2O2
CAS No. 51-21-8 SDF Download 5-FU (5-Fluorouracil) SDF
Smiles C1=C(C(=O)NC(=O)N1)F
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 26 mg/mL ( (199.87 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 10 mg/mL

Ethanol : Insoluble


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In vivo
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Frequently Asked Questions

Question 1:
I was wondering if the product #s1209 (5-fluorouracil) is suitable to inject into mice ?

Answer:
S1209 is suitable to inject (I.P.) into mice as indicating in this paper: http://www.ncbi.nlm.nih.gov/pubmed/8995503.

DNA/RNA Synthesis Signaling Pathway Map

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