D-(+)-Trehalose dihydrate

Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.

D-(+)-Trehalose dihydrate Chemical Structure

D-(+)-Trehalose dihydrate Chemical Structure

CAS: 6138-23-4

Selleck's D-(+)-Trehalose dihydrate has been cited by 2 publications

Purity & Quality Control

Batch: S399201 Water] 76 mg/mL] false] DMSO] 75 mg/mL] false] ] ] false Purity: 98%
98

Biological Activity

Description Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.
In vitro
In vitro Trehalose has been shown to play a key role in various types of stress-tolerance including radiation, cold and dehydration stresses in bacteria, yeast, nematodes, rotifers, tardigrades, certain crustaceans and insects. Studies on the role of trehalose in stress-tolerance suggest that trehalose must be presence on both sides of the cell membrane to confer protection. It is a non-charged and hydrophilic disaccharide which does not freely penetrate the mammalian cell membrane without external interventions[1].

Chemical lnformation & Solubility

Molecular Weight 378.33 Formula

C12 H22O11 . 2H2O

CAS No. 6138-23-4 SDF --
Smiles C(C1C(C(C(C(O1)OC2C(C(C(C(O2)CO)O)O)O)O)O)O)O.O.O
Storage (From the date of receipt)

In vitro
Batch:

Water : 76 mg/mL

DMSO : 75 mg/mL ( (198.23 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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