3,5-diiodo-L-thyronine (3,5-T2)

Synonyms: NSC 90469

3,5-diiodo-L-thyronine (3,5-T2, NSC 90469) is an endogenous metabolite of thyroid hormones. 3,5-Diiodo-l-thyronine has been proposed as a potential hypolipidemic agent for treatment of obesity and hepatic steatosis.The solubility of this product is not good, please choose carefully for cell experiments!

3,5-diiodo-L-thyronine (3,5-T2) Chemical Structure

3,5-diiodo-L-thyronine (3,5-T2) Chemical Structure

CAS: 1041-01-6

Purity & Quality Control

Batch: S647401 DMSO] Insoluble] false] Water] Insoluble] false] Ethanol] Insoluble] false Purity: 99.84%
99.84

Biological Activity

Description 3,5-diiodo-L-thyronine (3,5-T2, NSC 90469) is an endogenous metabolite of thyroid hormones. 3,5-Diiodo-l-thyronine has been proposed as a potential hypolipidemic agent for treatment of obesity and hepatic steatosis.The solubility of this product is not good, please choose carefully for cell experiments!
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
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NCT05558813 Not yet recruiting Duchenne Muscular Dystrophy Assistance Publique - Hôpitaux de Paris November 2024 Not Applicable
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Chemical lnformation & Solubility

Molecular Weight 525.08 Formula

C15H13I2NO4

CAS No. 1041-01-6 SDF --
Smiles C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)CC(C(=O)O)N)I
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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