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Mebrofenin

Synonyms: SQ 26962

Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA) that is available as a ready to use the kit for radio-labeling with Technetium-99m (Tc-99m). Tc-99m Mebrofenin is used clinical for hepatobiliary scintigraphy.

Mebrofenin Chemical Structure

Mebrofenin Chemical Structure

CAS: 78266-06-5

Purity & Quality Control

Batch: S358701 DMSO] 77 mg/mL] false] Ethanol] 20 mg/mL] false] Water] Insoluble] false Purity: 99.9%
99.9

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Biological Activity

Description Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA) that is available as a ready to use the kit for radio-labeling with Technetium-99m (Tc-99m). Tc-99m Mebrofenin is used clinical for hepatobiliary scintigraphy.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06126419 Recruiting Liver Dysfunction|Liver Metastasis Colon Cancer|Liver Regeneration McGill University Health Centre/Research Institute of the McGill University Health Centre November 8 2023 Not Applicable
NCT00767468 Terminated Liver Cancer UNC Lineberger Comprehensive Cancer Center|National Cancer Institute (NCI) October 2008 Phase 1

Chemical lnformation & Solubility

Molecular Weight 387.23 Formula

C15H19BrN2O5
CAS No. 78266-06-5 SDF --
Smiles CC1=C(Br)C(=C(NC(=O)CN(CC(O)=O)CC(O)=O)C(=C1)C)C
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 77 mg/mL ( (198.84 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 20 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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