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Catalog No.	Product Name	Information
A2003	Ramucirumab (anti-VEGFR2)	Ramucirumab is a monoclonal antibody of the IgG1 class that binds to VEGF-R2 and prevents its activation. The IC50 value for blocking KDR binding to VEGF is 0.8 nM for ramucirumab, MW: 143.6 KD.
S5597	(1R)-(-)-Menthyl acetate	(1R)-(-)-Menthyl acetate is a natural monoterpene which contributes to the smell and flavor of peppermint.
S9402	(20R)-Protopanaxadiol	(20R)-Protopanaxadiol, isolated from the roots of Panax ginseng, has protective effect on myocardial ischemia.
S9036	(20R)Ginsenoside Rh2	(20R)Ginsenoside Rh2, a natural compound found in Panax ginseng, shows antiviral and anticancer activities. It is a matrix metalloproteinase (MMP) inhibitor.,
S3333	(2R,3R)-(-)-2,3-Butanediol	(2R,3R)-(-)-2,3-Butanediol ((2R,3R)-Butane-2,3-diol) is an endogenous metabolite.
S2812	(R)-(-)-Gossypol (AT-101) acetic acid	(R)-(-)-Gossypol (AT-101) acetic acid, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with K_i of 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays; does not inhibit BIR3 domain and BID. AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy. Phase 2.
S5899	(R)-(-)-Ibuprofen	(R)-(-)-Ibuprofen ((R)-Ibuprofen) inhibits the activation of NF-κB in response to T-cell stimulation with IC50 of 121.8 μM, and exerts anti-inflammatory and antinociceptive effects.
S2965	(R)-(-)-JQ1 Enantiomer	(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 potently decreases expression of both BRD4 target genes, whereas (R)-(-)-JQ1 Enantiomer has no effect.
S9003	(R)-(-)-Mandelic acid	(R)-(-)-Mandelic acid is a synthetic intermediate useful for pharmaceutical synthesis.
S3320	(R)-3-Hydroxybutanoic acid	(R)-3-Hydroxybutanoic acid (R-3HB, D-3-hydroxybutyric acid) is a monomer of PHB (poly[(R)-3-hydroxybutyrate]) with wide industrial and medical applications. (R)-3-hydroxybutyric acid can also serve as chiral precursor for synthesis of pure biodegradable PHB and its copolyesters.
E0423	(R)-Avanafil	R-Avanafil is a strong competitive inhibitor of phosphodiesterase 5 (PDE5) with a demonstrated in vitro IC 50 of 5.2 nM.
S3072	(R)-baclofen	(R)-baclofen (STX 209) is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.
E0647	(R)-CR8 trihydrochloride	(R)-CR8 trihydrochloride, one of CR8 isomers, is a potent inhibitor CDK1/2/5/7/9 with antiproliferative effect and proapoptotic effect on CML cell lines.
S6675	(R)-GNE-140	(R)-GNE-140 is a selective inhibitor of the LDHA and LDHB with IC50s of 3 nM and 5 nM, respectively. The R enantiomer of GNE-140 is 18-fold more potent than S enantiomer.
S4926	(R)-Nepicastat HCl	(R)-Nepicastat HCl (RS-25560-198), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
S6224	(R)-Serine	(R)-Serine is the R-enantiomer of serine, which is used in the biosynthesis of proteins. (R)-Serine acts as obligatory coagonist at the glycine site associated with the N-methyl-D-aspartate subtype of glutamate receptors (NMDAR) and has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration.
E1257	(R,S)-3,5-DHPG Hydrochloride	(R,S)-3,5-DHPG hydrochloride (DHPG, Dihydroxy phenylglycine) is a salt of free amino acid dihydroxy phenylglycine (DHPG) which acts as a selective and potent agonist of group I metabotropic glutamate receptors (mGluR) (mGluR 1 and mGluR 5).
S0730	(Rac)-Antineoplaston A10	(rac)-Antineoplaston A10 is the racemate of Antineoplaston A10, which is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.
E2382	(Rac)-IBT6A	(Rac)-IBT6A (BTK inhibitor 1) is a racemate of IBT6A and an impurity of Ibrutinib, which is a Btk inhibitor (IC50=0.5 nM), and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.
S8920	(Rac)-JBJ-04-125-02	(Rac)-JBJ-04-125-02 (JBJ-04-125-02 racemate) is a mutant-selective allosteric inhibitor of Epidermal growth factor receptor (EGFR) with potential anticancer activity.
E0739	1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)	1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride (Anidulafungin Nucleus) is used in the commercialization and late-stage development of a semisynthetic antifungal anidulafungin/D-fructose.
P1210	11R-VIVIT TFA	11R-VIVIT TFA (NFAT inhibitor), a short peptide, inhibits NFAT activation through interaction with the calcineurin binding site for NFAT and thus prevents nuclear translocation without affecting calcineurin phosphatase activity.
E0492	20R-Camptothecin	20R-Camptothecin, one of Camptothecin Derivatives, has little or no effect on topoisomerase I, in contrast to the natural S isomer.
S6837	R-10015	R-10015 is a potent, selective inhibitor of LIM domain kinase (LIMK) with IC50 of 38 nM for human LIMK1. R-10015 binds to the ATP-binding pocket and acts as a broad-spectrum antiviral compound for HIV infection.
S7710	R-268712	R-268712 is a potent and selective inhibitor of ALK5 with an IC50 of 2.5 nM.
S6643	R-7050	R-7050 is a cell permeable TNF-α receptor antagonist and is 2.3-fold more selective for TNF-α-mediated signaling than for that driven by IL-1β.
S8420	R-IMPP	R-IMPP is an inhibitor of PCSK9 secretion, half maximal inhibitory concentration [IC50] = 4.8 μM.
E2856	R-Phycoerythrin	R-Phycoerythrin(R-PE), phycobiliproteins are isolated from Heterosiphonia japonica. R-Phycoerythrin is a novel strong fluorescent probe contains four chromophore-carrying subunits which exhibits extremely bright red-orange fluorescence.
S6519	R112	R112 is an ATP-competitive spleen tyrosine kinase (Syk) inhibitor with Ki value of 96 nM.
S0542	R1487	R1487 is an orally bioavailable and highly selective inhibitor of p38α with an ic50 value of 10 nM.
E2656	R1530	R1530 is a highly potent, orally bioavailable, dual-acting mitosis/angiogenesis inhibitor for the treatment of solid tumors, which can inhibit vascular endothelial growth factor receptor 2 (VEGFR2) and fibroblast growth factor receptors 1 (FGFR1) with IC50s of 10 nM and 28 nM, respectively.
E1170	R162	R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties.
S3479	R243	R243 is an inhibitor of Chemokine (C-C motif) receptor 8 (CCR8) signaling and chemotaxis.
S2194	R406	R406(R406 besylate) is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 induces apoptosis. Phase 1.
S1533	R406 (free base)	R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 (free base) triggers apoptosis. Phase 1.
S2688	R547	R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with K_i of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.
E0082	R59949	R59949, a diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM, inhibits inducible nitric oxide production through decreasing transplasmalemmal L-arginine uptake in vascular smooth muscle cells. R59949 strongly inhibits type I DGK a and γ, and moderately attenuates type II DGK θ and κ.
S6851	RA-190	RA190, a bis-benzylidine piperidon, is a potent, selective and oral effective inhibitor of proteasome ubiquitin receptor RPN13/ADRM1 with anticancer activity. RA190 triggers ER stress response, p53/p21 signaling axis and autophagy in multiple myeloma cells.
S0884	RA-9	RA-9 is a cell-permeable, potent and selective inhibitor of proteasome-associated deubiquitinating enzymes (DUBs) with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.
E3165	Rabdosiae Rubescentis Herba Extract	Rabdosiae Rubescentis Herba Extract is drawed from the dried aerial part of genus Rabdosia rubescens (Hemsl.) Hara of the Lamiaceae family, which possesses several biological activities, such as anti-bacteria, anti-parasites, anti-inflammation, and anticancer.
S4845	Rabeprazole	Rabeprazole(LY307640) is an oral inhibitor of proton pump and blocks the production of acid by the stomach.
S5885	Rabeprazole Related Compound E	Rabeprazole Related Compound E (Rabeprazole thioether) is an active metabolite of rabeprazole, which is a proton pump inhibitor.
S4665	Rabeprazole sodium	Rabeprazole (Aciphex, Dexrabeprazole, Habeprazole) is an antiulcer drug in the class of proton pump inhibitors.
S2626	Rabusertib (LY2603618)	Rabusertib (LY2603618, IC-83) is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated. Rabusertib (LY2603618) induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Rabusertib (LY2603618) induces bak-dependent apoptosis in AML cell lines.
S5705	Raceanisodamine	Raceanisodamine (7β-Hydroxyhyoscyamine) is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.
S2503	Racecadotril	Racecadotril (Acetorphan) is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM.
S9713	Racemetyrosine (SM-88)	Racemetyrosine (SM-88, Racemetirosine, DL-alpha-metyrosine, DL-alpha-Methyltyrosine) is a novel anti-cancer agent, used with melanin, phenytoin (a CYP3a4 inducer), and sirolimus (an mTOR inhibitor) (SMK Therapy).
E0125	Raclopride	Raclopride is a selective dopamine D2/D3 receptor antagonist that discriminates between dopamine-mediated motor functions. Raclopride binds to D2 and D3 receptors with dissociation constants of between 1.8 nM and 3.5 nM, but has a very low affinity for D4 receptors.
S9262	Raddeanin A	Raddeanin A (Raddeanin R3, NSC382873), a triterpenoid saponin from Anemone raddeana Regel, displays moderate inhibitory activity against histone deacetylases (HDACs) and has high antiangiogenic potency, antitumor activity.
S6644	Radiprodil (RGH-896)	Radiprodil (RGH-896) is a NR2B-selective NMDA receptor antagonist, initially developed for the treatment of neuropathic pain.
E3442	Radish leaves Extract	Radish Leaves Extractis extracted from the leaves of Raphanus sativus, which has antioxidant and anticancer properties.
E3441	Radish root Extract	Radish Root Extract is extrcated from Raphanus sativus, which has antidiabetic effects, and it is suitable for those with diabetes.
E3687	Radix Actinidiae Extract	Radix Actinidiae Extract is derived from Radix Actinidiae, also known as the root of Actinidia chinensis Planch., which can play an anticancer role by regulating microRNA (miRNA) expression.
E3689	Radix Asparagi Extract	Radix Asparagi Extract is extracted from the dry root of Asparagus cochinchinensis (Lour.) Merr.(Liliaceae). Asparagi radix is efficacious against inflammation diseases due to its high antioxidant activity. The extract from Asparagi radix can inhibit browning reaction of mushroom, similar to ascorbic acid.
E3898	Radix Asteris Extract	Radix Asteris Extract is extracted from the root and rhizome of Aster tataricus L. f., which has been used to treat cough and asthma.
E3590	Radix berberidis Extract	Radix Berberidis Extract is extracted from Berberis sargentiana.
E3845	Radix Curcumae Root Extract	Radix Curcumae Root Extract is extracted from the roots of Curcuma longa L., which has antitumor and anti-metastatic activities and can be used for treatment and prevention of breast cancer metastasis.
E3785	Radix Dipsaci Extract	Radix Dipsaci Extract is extracted from Dipsacus asper, which has anti-osteoporosis efficacy.
E3408	Radix Euphorbiae Ebracteolatae Extract	Radix Euphorbiae Ebracteolatae Extract is extracted from Radix Euphorbiae Ebracteolatae, which modulates aquaporins via inhibiting PKC activity in the kidney.
E3465	Radix Ophiopogonis Extract	Radix Ophiopogonis Extract is extracted from Radix Ophiopogonis, which has antidiabetic activity.
E3557	Radix Peucedani Extract	Radix Peucedani Extract is derived from Peucedani radix (Qianhu), which has strong anti-inflammatory properties and has been an important agent for treating respiratory symptoms and diseases through the centuries.
E3369	Radix Platycodonis Extract	Radix Platycodonis Extract is extracted from Platycodon grandiflorus, which has various pharmacological activities.
E3851	Radix Polygalae Extract	Radix Polygalae Extract is extracted from Radix Polygalae, which is used for the treatment of various psychiatric disorders.
E3559	Radix rubiae Extract	Radix Rubiae Extract is extracted from Rubia cordifolia, which has anti-tumor, anti-oxidative, anti-platelet aggregation, and anti-inflammatory effects.
E3786	Radix Scrophulariae Extract	Radix Scrophulariae Extract is derived from Radix Scrophulariae, which has anti-apoptotic and anti-inflammatory effects, potentially operating by affecting the mitogen-activated protein kinases (MAPKs) signaling pathway and inhibition of the NF-κB pathway.
E3594	Radix tetrastigme Extract	Radix Tetrastigme Extract is extracted from Tetrastigma hemsleyanum, which can modulate TLR4/COX-2/NF-κB signaling pathway.
E3352	Radix Tinosporae Extract	Radix Tinosporae Extract is extracted from Radix Tinosporae, which is a traditional Chinese medicine for the treatment of various inflammatory diseases.
S8134	Radotinib	Radotinib (IY-5511) is a selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM, used to treat Chronic Myeloid Leukemia.
E2651	Raf inhibitor 1	Raf inhibitor 1 is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-Raf ^WT, B-Raf ^V600E, and C-Raf, respectively.
E0934	Raf inhibitor 2	Raf inhibitor 2 is a potent Raf kinase inhibitor with an IC50 of <1.0 μM.
S2161	RAF265 (CHIR-265)	RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM in cell-free assays. RAF265 (CHIR-265) induces cell cycle arrest and apoptosis. Phase 2.
S5155	Raffinose	Raffinose (Melitose, Melitriose) is a complex carbohydrate, a trisaccharide composed of galactose, fructose, and glucose. It can be broken apart into galactose and sucrose via the enzyme alpha-galactosidase.
S5093	Rafoxanide	Rafoxanide (Disalan, Ranide, Flukanide, Bovanide) is a salicylanilide used as an anthelmintic, being effective treatment for the control of fluke infections in animals.
S1494	Ralimetinib (LY2228820) dimesylate	Ralimetinib (LY2228820) dimesylate is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, does not alter p38 MAPK activation. Phase 1/2.
S5781	Raloxifene	Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.
S1227	Raloxifene HCl	Raloxifene (LY156758, Keoxifene) HCl is a selective and orally active estrogen receptor modulator (SERM), which inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM.
S2005	Raltegravir	Raltegravir is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000-fold selectivity for HIV-1 IN over several related Mg2+-dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.
S5245	Raltegravir potassium	Raltegravir Potassium(MK-0518 potassium) is the orally bioavailable potassium salt of raltegravir, the first approved human immunodeficiency virus type 1 (HIV-1) integrase inhibitor.
S1192	Raltitrexed	Raltitrexed (ZD-1694) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.
S5286	Ramatroban	Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.
E3286	Rambutan Extract	Rambutan Extract is extrcated from Nephelium lappaceum, which improves blood pressure and other metabolic parameters.
S1259	Ramelteon	Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with K_i of 14 pM, 112 pM and 23.1 pM, respectively.
S1793	Ramipril	Ramipril(HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
S3723	Ramosetron Hydrochloride	Ramosetron Hydrochloride (YM-060) is the hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity.
E3603	Ramulus Mori Extract	Ramulus Mori Extract is extracted from Ramulus mori (Mulberry twigs), the dry branch of Morus alba L.. Ramulus Mori is a traditional medicine widely used for diabetes treatment. The major active components of Ramulus Mori are mulberroside A, oxyresveratrol, resveratrol, 4-hydroxycinnamic acid, 7-hydroxycoumarin, and morin, and the components have been demonstrated to possess anti-cancer, anti-hypertensive, anti-diabetic, and anti-inflammatory properties.
S5662	Ranitidine	Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.
S1801	Ranitidine Hydrochloride	Ranitidine (AH19065) is a histamine H2-receptor antagonist, used to treat stomach or intestinal ulcers.
S1799	Ranolazine	Ranolazine (CVT 303, RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina.
S1425	Ranolazine 2HCl	Ranolazine 2HCl (RS-43285,RS 43285-193,Ranexa, renolazine,Ranolazine dihydrochloride) is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.
S8267	RapaLink-1	RapaLink-1, a third-generation bivalent inhibitor of mTOR, combines Rapamycin with MLN0128 using an inert chemical linker. It demonstrates efficacy against resistant mutants of malignant brain tumors and inhibits cancer cell progression by binding to mesenchymal markers.
S1039	Rapamycin (Sirolimus)	Rapamycin (Sirolimus) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
S6907	Rapastinel (GLYX-13)	Rapastinel (GLYX-13, BV-102, TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targeting a glycine site. Rapastinel has long-lasting antidepressant effects.
E3404	Raphanus sativus seed Extract	Raphanus sativus seed Extract is extracted from the seeds of Raphanus sativus, which has wound-healing characteristics.
S0528	Raphin1	Raphin1 is an orally bioavailable, selective inhibitor of R15B (PPP1R15B, a regulatory subunit of protein phosphatase 1). Raphin1 binds strongly to the R15B-PP1c holophosphatase with Kd of 33 nM.
S0744	Raphin1 acetate	Raphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 acetate binds strongly to the R15B-PP1c holophosphatase with Kd of 0.033 μM.
S5795	Rasagiline	Rasagiline (TVP-1012) is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively.
S2102	Rasagiline Mesylate	Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.
S9480	Raspberry Ketone	Raspberry ketone (p-Hydroxybenzyl acetone, Frambinone, Oxyphenylon, Rheosmin, Rasketone) is a natural phenolic compound that is the primary aroma compound of red raspberries. Raspberry ketone shows cardioprotective action against isoproterenol-induced myocardial infarction in rats, and the effects may be due to its PPAR-α agonistic activity.
S3222	Raspberry ketone glucoside	Raspberry ketone glucoside (RKG), a natural product in raspberry fruit, is an antioxidant that has the inhibitory effect on the melanin synthesis.
A2119	Rat IgG1 isotype control-InVivo	Rat IgG1 isotype control-InVivo monoclonal antibody (Clone:HRPN) reacts with horseradish peroxidase (HRP). Because HRP is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG1 antibodies in most in vivo and in vitro applications.
A2123	Rat IgG2a isotype control-InVivo	Rat IgG2a isotype control-InVivo can be used as an isotype-matched control for rat IgG2a antibodies.
A2116	Rat IgG2b isotype control-InVivo	Rat IgG2b isotype control-InVivo monoclonal antibody (Clone:LTF-2) reacts with keyhole limpet hemocyanin (KLH). Because KLH is not expressed by mammals this antibody is ideal for use as an isotype-matched control for rat IgG2b antibodies in most in vivo and in vitro applications.
S5337	Rauwolscine hydrochloride	Rauwolscine hydrochloride (Isoyohimbine, α-Yohimbine, corynanthidine) is the hydrochloride salt form of Rauwolscine, a specific and potent α2 antagonist with Ki of 12 nM.
S7554	Ravoxertinib (GDC-0994)	Ravoxertinib (GDC-0994) is a potent, orally available and highly selective ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1.
S7606	RBC8	RBC8 is a selective inhibitor of the GTPases RalA and RalB by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases Ras and RhoA.
S8376	Rbin-1	Rbin-1 (Ribozinoindole-1) is a potent chemical inhibitor of eukaryotic ribosome assembly. It inhibits recombinant full-length Mdn1's ATPase activity in vitro.
S8992	RBN012759	RBN012759 is a potent and selective inhibitor of PARP14 with IC50 of <3 nM and 5 nM for human catalytic domain and mouse catalytic domain, respectively. RBN012759 contributes to anti-tumor immune response.
E1305	RBN013209	RBN013209 is a potent inhibitor of CD38 with an IC50 of 0.01-0.1 μM for human CD38. It can be used for the research of cancer.
S6579	RCGD423	RCGD-423 is a modulator of Glycoprotein 130 (gp130, IL6ST, IL6-beta, CD130) signalling that regulates cartilage growth and differentiation.
S6898	RCM-1	RCM-1 is a nontoxic inhibitor of Forkhead box M1 (FOXM1) that suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice. RCM-1 decreases carcinogenesis and nuclear β-catenin.
S8187	ReACp53	ReACp53 is a cell-penetrating peptide, designed to inhibit p53 amyloid formation, resues p53 function in cancer cell lines and in organoids derived from high-grade serous ovarian carcinomas (HGSOC).
S2032	Rebamipide	Rebamipide (OPC-12759,Proamipide) is a cholecystokinin type 1 (CCK1) receptor inhibitor for inhibiting [¹²⁵I]BH-CCK-8S with IC50 of 37.7 μM.
E0948	Rebamipide mofetil	Rebamipide mofetil is an orally active prodrug of Rebamipide (OPC12759). Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner.
S2634	Rebastinib (DCC-2036)	Rebastinib (DCC-2036) is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1.
S3796	Rebaudioside A	Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste. Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels.
S3257	Rebaudioside B	Rebaudioside B (Reb B) is one of the minor steviol glycosides (SGs) isolated from Stevia rebaudiana and has a better taste quality than many of the major SGs.
S4742	Rebaudioside C	Rebaudioside C (Dulcoside B) belongs to the family of Steviol Glycosides. It is a natural constituent of the plant Stevia rebaudiana Bertoni and used as natural sweeteners to diabetics and others on carbohydrate-controlled diets.
S3259	Rebaudioside D	Rebaudioside D (Reb D) is one of the several glycosides (SGs) found in the leaves of Stevia rebaudiana (Bertoni) which has been identified as a potential sweetener.
S3282	Rebaudioside M	Rebaudioside M, isolated from Stevia rebaudiana Bertoni, is a natural non-caloric potential sweetener in food and beverage products.
S3199	Reboxetine mesylate	Reboxetine (PNU 155950E) is a norepinephrine reuptake inhibitor with K_i of 8.2 nM.
E2947	Recilisib	Recilisib (ON01210, EX-RAD) is a radioprotectant that activates the activity of AKT and PI3K in cells. It has been studied as prophylactic (use prior to radiation exposure) and therapeutic (after exposure to radiation) drug.
E3283	Red Bean Extract	Red Bean Extract is extracted from Red Beans, which possess various functional properties, such as anti-diabetes, anti-aging, anti-inflammatory, anticancer, and hepatoprotective activities.
E3891	Red Cabbages Extract	Red Cabbages Extract is extracted from Brassica oleracea L., which helps to treat diseases not only involving dyslipidemic conditions but also oxidative stress.
E3276	Red Ginseng Extract	Red Ginseng Extract is derived from Red Ginseng, which can increase the human body's anti-inflammatory and anticancer immunity.
E3288	Red Raspberry Extract	Red Raspberry Extract is extracted from Rubus idaeus, which is rich in bioactive components that plays a role in reduction oxidative stress.
E3287	Red Yeast Rice Extract	Red Yeast Rice Extract is extracted from Monascus purpureus, which is the most effective cholesterol-lowering nutraceutical.
E3428	Reed rhizome Extract	Reed rhizome Extract is extracted from the root of Phragmites australis.
S1089	Refametinib (RDEA119)	Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
S5358	Regadenoson	Regadenoson (CVT-3146, Lexiscan) is a selective A2A adenosine receptor agonist with coronary vasodilating activity.
S1178	Regorafenib	Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy.
S5077	Regorafenib (BAY-734506) Monohydrate	Regorafenib (BAY-734506, Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, Kit (c-Kit), RET (c-RET), RAF-1, B-RAF and B-RAF(V600E) respectively.
S4947	Regorafenib Hydrochloride	Regorafenib (Stivarga, BAY 73-4506) Hydrochloride is a multi-target inhibitor for VEGFR1, Murine VEGFR2/3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM, 4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.
E3632	Rehmanniae Radix Extract	Rehmanniae Radix Extract is extracted from Rehmannia to treat skeletal diseases in traditional Chinese medicine and is a potent anti-osteoporotic.
E3652	Rehmanniae radix praeparata Extract	Rehmanniae radix praeparata Extract is extracted from Rehmanniae radix praeparata, which can improve diabetes through AMPK-mediated NF-κB/NLRP3 signaling pathway.
E0248	Rehmannioside D (Rhmannioside D)	Rehmannioside D (Rhmannioside D) is an iridoid glycoside that has been found in Rehmannia glutinosa.
E1091	Relacorilant (CORT125134)	Relacorilant (CORT125134) is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively.
A2029	Relatlimab (anti-LAG-3)	Relatlimab (BMS-986016, RELA) is a human LAG-3 specific monoclonal antibody that binds to LAG-3 on T cells, restoring effector function of exhausted T cells.
S0074	Relebactam	Relebactam (MK-7655) is a potent inhibitor against KPC-2, class A and class C (AmpC) β-lactamases.
S5808	Relugolix	Relugolix (RVT-601, TAK-385) is a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR, respectively.
S8932	Remdesivir (GS-5734)	Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.
S9660	Remibrutinib	Remibrutinib is a potent, highly selective covalent inhibitor of bruton tyrosine kinase (BTK) with IC50 of 1.3 nM, 2.5 nM and 18 nM for BTK, FcγR-induced IL8 and anti-IgM/IL4-induced CD69, respectively. Remibrutinib (LOU064) exhibits an exquisite kinase selectivity due to binding to an inactive conformation of BTK and has the potential for the treatment of autoimmune diseases.
S7641	Remodelin hydrobromide	Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor.
S0993	Remogliflozin etabonate (GSK189075)	Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity inhibitor of sodium glucose cotransporter (SGLT2) with Ki of 1950 nM, 2140 nM, 43100 nM, 8570 nM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models.
S1426	Repaglinide	Repaglinide (AG-EE 623 ZW) is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used the treatment of type II diabetes.
S8640	Reparixin (Repertaxin)	Reparixin (Repertaxin, DF 1681Y) is a potent and specific inhibitor of CXCR1 with IC50 of 1 nM. Reparixin (Repertaxin) inhibits PMN migration induced by CXCL8 (IC50 = 1 nM) and rodent PMN chemotaxis induced by CXCL1 and CXCL2. Repertaxin inhibits the response of human PMN to CXCL1, which interacts with CXCR2 (IC50 = 400 nM).
S8583	Repotrectinib (TPX-0005)	Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM).
S7223	RepSox (E-616452)	RepSox (E-616452, SJN 2511, ALK5 Inhibitor II) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation in cell-free assays, respectively.
S7455	Resatorvid (TAK-242)	Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.
S1601	Reserpine	Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
S3238	Resibufogenin	Resibufogenin (Bufogenin, Recibufogenin), a component of huachansu with anticancer effect, triggers necroptosis through upregulating receptor-interacting protein kinase 3 (RIP3) and phosphorylating mixed lineage kinase domain-like protein at Ser358. Resibufogenin exerts cytotoxic effect by inducing reactive oxygen species (ROS) accumulation. Resibufogenin induces apoptosis and caspase-3 and caspase-8 activity. Resibufogenin increases Bax/Bcl-2 expression, and suppresses cyclin D1, cyclin E, PI3K, p-AKT, p-GSK3β and β-catenin protein expression.
S8133	Resiquimod (R-848)	Resiquimod (R-848, S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Resiquimod reduces hepatitis C virus (HCV) infection. Phase 2.
S6663	Resmetirom (MGL-3196)	Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective thyroid hormone receptor β(THR-β) agonist with an EC50 of 0.21 μM,shows 28-fold selective for THR-β over THR-α in a functional assay.
S2693	Resminostat	Resminostat (RAS2410) dose-dependently and selectively inhibits HDAC1/3/6 with IC50 of 42.5 nM/50.1 nM/71.8 nM, less potent to HDAC8 with IC50 of 877 nM.
S4882	Resorantel	Resorantel is a safe, hydroxybenzanilide cestocide highly effective against Moniezia and Thysaniezia spp. and moderately effective against Paramphistomum spp.
S4579	Resorcinol	Resorcinol is a chemical compound that serves as an antiseptic,an disinfectant, and a chemical intermediate for the production of many other pharmaceuticals.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S1396	Resveratrol	Resveratrol has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases（LOX, IC50=2.7 μM）, kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol induces mitophagy/autophagy and autophagy-dependent apoptosis.
S4056	Retapamulin	Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with K_d of 3 nM.
S4734	Retigabine 2HCl	Retigabine 2HCl (D-23129) is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.
E3663	Retinerus luffae Fructus Extract	Retinerus Luffae Fructus Extract is extracted from the vascular bundle of the fruit of Luffa aegyptiaca Miller.
S1653	Retinoic acid (Tretinoin)	Retinoic acid (Tretinoin), which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.
S4126	Retinyl (Vitamin A) Palmitate	Retinyl (Vitamin A) Palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid.
S5058	Revaprazan Hydrochloride	Revaprazan Hydrochloride (YH1885) is a new reversible proton pump inhibitor with long-lasting acid-suppressive effects. Revaprazan Hydrochloride reversibly inhibits H(+)/K(+)-ATPase via binding to the K+-binding site of the pump.
S5258	Revefenacin	Revefenacin (TD-4208, GSK-1160724) is a potent, lung-selective, long-acting muscarinic antagonist that may be for the treatment of respiratory disease.
E1742	Reversan	Reversan (CBLC4H10) is a selective and nontoxic inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp), with the potential to treat neuroblastoma and other MRP1-overexpressing drug-refractory tumors.
S7588	Reversine	Reversine is a potent human A3 adenosine receptor antagonist with K_i of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 400 nM/500 nM/400 nM, respectively. Also used for stem cell dedifferentiation.
S8996	Revumenib (SNDX-5613)	Revumenib(SNDX-5613) is a potent and selective inhibitor of menin-MLL binding with a Ki of 0.15 nM. SNDX-5613 shows anti-proliferative activity against multiple cell lines harboring MLLr translocations (MV4;11, RS4;11, MOLM-13, KOPN-8) with IC50 values ranging from 10-20 nM.
S2115	RG 13022	RG 13022 (Tyrphostin RG13022) inhibits the autophosphorylation reaction of the EGF receptor in immunoprecipitates with IC50 of 4 µM.
S7030	RG-7112	RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor with HTRF IC50 of 18 nM.
S2821	RG108	RG108 (N-Phthalyl-L-tryptophan) is an inhibitor of DNA methyltransferase with IC50 of 115 nM in a cell-free assay, does not cause trapping of covalent enzymes.
S6523	RG14620	RG14620 (Tyrphostin RG14620), an EGFR inhibitor of the tyrphostin family, directly inhibits the transport function of ABCG2/BCRP.
S7292	RG2833 (RGFP109)	RG2833 (RGFP109) is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3 in cell-free assays, respectively.
S0063	RG3039	RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4.2 nM and IC90 of 40 nM, respectively.
E2821	RGB-286638 free base	RGB-286638 free base is a Cyclin-dependent kinase (CDK) inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM.
S8008	RGD (Arg-Gly-Asp) Peptides	RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
S4513	RGD peptide (GRGDNP)	RGD peptide (GRGDNP) is an inhibitor of binding of integrins to the extracellular matrixs. RGD peptide (GRGDNP) induces apoptosis presumably through direct activation of caspase-3.
E1223	RGX-202	RGX-202 is an SLC6A8 transporter inhibitor which suppress the colon cancer tumor. In addition to significantly reducing intracellular phosphocreatine and ATP levels and inducing tumour apoptosis, RGX-202 also inhibits creatine import both in vitro and in vivo.
S3461	RH01687	RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.
E0245	Rhamnose	Rhamnose(L-Rhamnose) is an important 6-deoxy sugar present in many natural products, glycoproteins, and structural polysaccharides.
E3812	Rhamnus Cathartica Extract	Rhamnus Cathartica Extract is extracted from Rhamnus cathartica, which has antimicrobial activity.
S9163	Rhapontigenin	Rhapontigenin (Protigenin), produced from rhapontin isolated from a methanol extract of Rheum undulatum roots by enzymatic transformation, is a selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM).
S9083	Rhapontin	Rhapontin (Ponticin, Rhaponticin, Rhapontigenin glucoside), a stibene-type glycoside distributed widely in medicinal plants of Rheum genus (Polygonaceae), has anti-inflammatory effect and anti-proliferative activity.
S0766	RHC 80267	RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase (DAGL, DAG lipase) with IC50 of 4 μM for cholinesterase activity. RHC 80267 inhibits cyclooxygenase (COX) activity, phospholipase C (PLC) activity and the hydrolysis of phosphatidylcholine (PC).
S2400	Rheic Acid	Rhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N⁶-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes.
S2395	Rheochrysidin	Rheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill.
E3861	Rhizoma Alismatis Extract	Rhizoma Alismatis Extract is extracted from Alismatis rhizoma, which has therapeutic effects on metabolic syndrome.
E3418	Rhizoma Anemones Raddeanae Extract	Rhizoma Anemones Raddeanae Extract is extracted from the rhizome of Anemone raddeana Regel, which is used to treat wind and cold symptoms, hand-foot disease and spasms, joint pain, and ulcer pain.
E3313	Rhizoma Coptidis Fibrous Root Extract	Rhizoma Coptidis Fibrous Root Extract is extracted from Rhizoma Coptidis Fibrous Root.
E3312	Rhizoma Coptidis Root Extract	Rhizoma Coptidis Root Extract, isolated from the dried roots of medicinal plants from Rhizoma coptidis (Ranunculaceae), has been used by Chinese medicinal physicians for more than 2000 years.
E3850	Rhizoma Corydalis Extract	Rhizoma Corydalis Extract is extracted from Rhizoma corydalis, which can be used to prevent relapse to chronic drug dependence.
E3232	Rhizoma Drynariae Extract	Rhizoma Drynariae Extract is extracted from Rhizoma Drynariae.
E3358	Rhizoma Fagopyri Dibotryis Extract	Rhizoma Fagopyri Dibotryis Extract is extracted from Rhizoma Fagopyri Dibotryis, which is used in the treatment of acute lung injury.
E3554	Rhizoma homalomenae Extract	Rhizoma Homalomenae Extract is extracted from Rhizoma Homalomenae, which has anti-inflammatory activity.
E3055	Rhizoma Menispermi Extract	Rhizoma Menispermi Extract is extracted from Menispermum dauricum DC, which possesses significant bioactivities that include anti-cancer and anti-hypoxia effects.
E3880	Rhizoma Paridis Extract	Rhizoma Paridis Extract is extracted from Rhizoma paridis, which has anti-angiogenesis effects.
E3311	Rhizoma polygonati root Extract	Rhizoma Polygonati Root Extract, isolated from the roots of Rhizoma polygonati, has been used for a long history with many chemical components in inducing anti-cancer, anti-aging, anti-diabetes, anti-fatigue, and more prevention of diseases or acts as nutrition sources in food.
S3577	Rhodamine 123	Rhodamine 123 (RH-123, R-22420) is a fluorescent cationic dye used to label mitochondria in living cells. Rhodamine 123 inhibits ADP-stimulated respiration of mitochondria with Ki = 12 μM and ATPase activity of inverted inner membrane vesicles with Ki of 126 μM and partially purified F1-ATPase with Ki of 177 μM.
S3593	Rhodamine 6G	Rhodamine 6G (R6G, Basic Red 1, Rhodamine 590) is a fluorescence tracer that binds to mitochondria, thus reducing the intact mitochondria number and inhibiting mitochondrial metabolic activity.
S5641	Rhodamine B	Rhodamine B is used as a tracer dye in water to determine the rate and direction of flow and transport. It is a staining fluorescent dye used in fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA in biotechnology fields.
E3285	Rhodiola Rosea Extract	Rhodiola Rosea Extract is extracted from Rhodiola Rosea.
S9084	Rhoifolin	Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
S8988	Rhosin hydrochloride	Rhosin (G04) hydrochloride (HCl) is a potent, specific inhibitor of RhoA subfamily Rho GTPases with Kd of ~ 0.4 uM. Rhosin hydrochloride induces cell apoptosis.
S8118	RHPS 4 methosulfate	RHPS4 (NSC714187) is a potent inhibitor of Telomerase at submicromolar.
E3123	Rhubarb Extract	Rhubarb Extract is obtained from Rheum palmatum L./Rheum officinale, of which phytochemicals could promote some bacterial genders involved in gut barrier function, therefore be involved in the modulation of the susceptibility to hepatic diseases linked to acute alcohol consumption.
S9400	Rhynchophylline	Rhynchophylline (Mitrinermine), an active component isolated from species of the genus Uncaria, acts as a calcium channel blocker and is widely used in traditional Chinese medicine mainly for treating ailments of central nervous and cardiovascular systems, such as lightheadedness, convulsions, numbness, and hypertension.
S8077	RI-1	RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.
S3553	Riamilovir	Riamilovir (Triazavirin) is a broad-spectrum antiviral drug candidate, which can be used for potential application against the Coronavirus 2019-nCoV.
S2504	Ribavirin (ICN-1229)	Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.
E3901	Ribes Henryi Root Extract	Ribes Henryi Root Extract is extracted from the root of Ribes Henryi.
S2612	Ribitol	Ribitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
S7440	Ribociclib	Ribociclib is an orally available, and highly specific inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM. Phase 3.
S5187	Ribociclib hydrochloride	Ribociclib (LEE011) hydrochloride is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM, respectively.
S5188	Ribociclib succinate	Ribociclib (LEE011) succinate is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM, respectively.
S2540	Riboflavin	Riboflavin (Vitamin B2, E101) is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
S5107	Riboflavin phosphate sodium	Flavin mononucleotide (riboflavin-5'-phosphate, FMN) is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as prosthetic group of various oxidoreductases including NADH dehydrogenase as well as cofactor in biological blue-light photo receptors.
S6441	Riboflavin Tetrabutyrate	Riboflavin tetrabutyrate is a lipophilic flavin derivative with antioxidative and lipid peroxide-removing activity.
E4006	Ribonucleic acid	Ribonucleic Acid (RNA) is the substrate for the RNase enzyme, which can be used for studying ribonuclease activities of enzymes such as ribonuclease-A, ribonuclease T1 (RNAase), and bougainvillea xbuttiana antiviral protein 1 (BBAP1).
S4215	Ribostamycin Sulfate	Ribostamycin Sulfate(Vistamycin Sulfate,Landamycine) is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidiﬁcus.
E3126	Rice Extract	Rice Extract is extracted from Oryza sativa, which has the benefit of preventing fatty liver in postmenopausal women.
E3127	Rice Flour Extract	Rice Flour Extract is extracted from Oryza sativa, which supports liver health as it contains choline and is also gluten-free, which is safe for people with celiac disease.
E4092	Ricinoleic acid	Ricinoleic acid is a hydroxy fatty acid. It is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings.
S8001	Ricolinostat (ACY-1215)	Ricolinostat (ACY-1215, Rocilinostat) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. Ricolinostat (ACY-1215) suppresses cell proliferation and promotes apoptosis. Phase 2.
S1022	Ridaforolimus (Deforolimus, MK-8669)	Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line; while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to rapamycin. Phase 3.
S1741	Rifabutin (LM427)	Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.
S1764	Rifampin (Rifampicin)	Rifampin (Rifampicin) is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.
S4425	Rifamycin S	Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S5054	Rifamycin sodium salt	Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.
S1760	Rifapentine	Rifapentine (MDL473) is an antibiotic, which inhibits DNA-dependent RNA polymerase activity, used to treat tuberculosis.
S1790	Rifaximin	Rifaximin is a RNA synthesis inhibitor by binding the β subunit of the bacterial DNA-dependent RNA polymerase, used to treat traveler's diarrhea caused by certain bacteria.
S1362	Rigosertib (ON-01910)	Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells. Phase 3.
E1398	Rilematovir	Rilematovir (JNJ-678, JNJ-53718678) is an antiviral agent that inhibits respiratory syncytial virus (RSV) with EC50 of 1.2 nM in HBECs. Rilematovir is also a fusion protein inhibitor.
S7548	Rilmenidine Phosphate	Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used for the treatment of hypertension.
A2469	Rilotumumab (Anti-HGF / SF)	Rilotumumab (Anti-HGF / SF) is a monoclonal antibody that inhibits HGF/MET-driven signaling. Rilotumumab shows anti-tumor activity, and can be used in castration-resistant prostate cancer (CRPC) and solid tumor research. MW: 145.5 KD.
S7303	Rilpivirine	Rilpivirine (R278474, TMC27, DB08864) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.
E0815	Rilpivirine Hydrochloride	Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
S1614	Riluzole	Riluzole is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic qualities.
S1964	Rimantadine	Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
S5484	Rimantadine Hydrochloride	Rimantadine is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza. It works by inhibiting a viral protein called M2, which normally mediates the transport of acid ions across the influenza virion shell.
S6659	Rimegepant (BMS-927711)	Rimegepant (BMS-927711, BHV-3000) is a potent, selective, competitive human calcitonin gene-related peptide (CGRP) receptor antagonist with ki of 0.027 nM.
S0312	Rimeporide	Rimeporide(EMD-87580) is a sodium hydrogen exchanger (NHE-1) inhibitor indicated for patients with Duchenne muscular dystrophy.
S9726	Rimiducid (AP1903)	Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.
S3021	Rimonabant (SR141716)	Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.
S3376	RIN1 (RBPJ Inhibitor-1)	RIN1 (RBPJ Inhibitor-1) is a potent inhibitor of the transcription factor RBPJ that disrupts the interaction between NOTCH and RBPJ.
A2378	Rinucumab (Anti-PDGFRB / CD140b)	Rinucumab (Anti-PDGFRB / CD140b) is an anti-platelet-derived growth factor receptor beta (anti-PDGFR-beta) monoclonal antibody and has a potential to study neovascular age-related macular degeneration. MW: 145.5 kD.
S8135	Riociguat	Riociguat is an oral soluble guanylate cyclase (GC) stimulator, used in the treatment of ipulmonary hypertension.
S6511	RIPA-56	RIPA-56 is a highly-potent, selective, and metabolically stable RIP1 (RIPK1) inhibitor.
S7995	Ripasudil hydrochloride dihydrate	Ripasudil hydrochloride dihydrate is a potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.
E2648	RIPK1-IN-7	RIPK1-IN-7 is a potent and selective receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM.
S8757	Ripretinib	Ripretinib is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of the tumor-associated antigens (TAA) mast/stem cell factor receptor (SCFR) Kit (c-Kit) and PDGFR-alpha, with IC50 values of 4 nM, 8 nM, 18 nM, 5 nM and 14 nM for WT Kit (c-Kit), V654A Kit (c-Kit), T670I Kit (c-Kit), D816H Kit (c-Kit) and D816V Kit (c-Kit), respectively.
A2046	Risankizumab (anti-IL-23)	Risankizumab targets the p19 subunit of IL-23. Risankizumab is indicated for the treatment of psoriasis and is safe and effective in maintaining remission in active Crohn's disease.
S6925	Risdiplam	Risdiplam is an orally administered SMN2 pre-mRNA splicing modifier that distributes into the central nervous system (CNS) and peripheral tissues.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S1874	Risedronate	Risedronate (Risedronic Acid) is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.
S1428	Risedronate Sodium	Risedronate (NE 58095) sodium, a nitrogen-containing bisphosphonate, inhibits osteoclast-mediated bone resorption and modulates bone metabolism, used in the treatment of osteoporosis.
S1615	Risperidone	Risperidone (R-64766) is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.
S2781	RITA	RITA induces both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks, and also inhibits MDM2-p53 interaction by targeting p53.
S5251	Ritalinic acid	Ritalinic acid (α-phenylpiperidine-2-acetic acid) is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate. Ritalinic acid can be biodegraded and used as a sole carbon and nitrogen source by various microbial strains originating from different environmental samples.
S8538	Ritlecitinib (PF-06651600)	Ritlecitinib (PF-06651600) is a potent and irreversible JAK3-selective inhibitor with an IC50 of 33.1 nM but without activity (IC50 > 10 000 nM) against JAK1, JAK2, and TYK2.
S2533	Ritodrine HCl	Ritodrine HCl (NSC 291565,DU 21220, Ritodrine) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.
S1185	Ritonavir	Ritonavir is a Cytochrome P450 3A and Protease Inhibitor; Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP Glucuronosyltransferases. Ritonavir induces apoptosis.
A2009	Rituximab (anti-CD20)	Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM, MW: 143.86 KD.
S3002	Rivaroxaban	Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively. It is selective for human factor Xa, for which it has >10 000-fold greater selectivity than for other biologically relevant serine proteases (IC50 >20 μM).
S4687	Rivastigmine	Rivastigmine (SDZ-ENA 713, Exelon) is a cholinesterase inhibitor with IC50 of 5.5 μM. It inhibits acetylcholinesterase (IC50 = 4.15 µM) and butyrylcholinesterase (IC50 = 37 nM).
S2087	Rivastigmine Tartrate	Rivastigmine Tartrate (ENA 713) is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.
S8058	Riviciclib hydrochloride (P276-00)	Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Riviciclib hydrochloride (P276-00) induces apoptosis. Phase 2/3.
S1607	Rizatriptan Benzoate	Rizatriptan Benzoate (MK-462) is an agonist at serotonin 5-HT1B and 5-HT1D receptors, used to treat acute migraine attacks.
S0020	RK 24466	RK-24466 (KIN 001-51, Lck inhibitor C 8863, C8863) is a potent and selective inhibitor of Lck that inhibits two constructs of the human lck kinase, lck (64-509) and lckcd with IC50 of < 0.001 μM and 0.002 μM, respectively.
S8876	RK-287107	RK-287107 is a novel, potent and selective tankyrase inhibitor with antitumor activity. RK-287107 inhibits tankyrase-1 and tankyrase-2 in vitro with IC50 of 14.3 nM and 10.6 nM.
S8246	RK-33	RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.
S8718	RMC-4550	RMC-4550 is a potent SHP-2inhibitor with an IC50 of 1.55 nM and it has no significant activity vs. 468 kinases, the catalytic domain of 15 phosphatases and other cellular targets including GPCRs, transporters and ion channels.
S9969	RMC-4630	RMC-4630 (SSE15206) is an inhibitor of microtubule polymerization with a GI50 of 197 nM in HCT116 cells. It can overcome multidrug resistance and cause aberrant mitosis, resulting in G2/M arrest due to incomplete spindle formation in cancer cells.
E1597	RMC-6236
E1606	RMC-6291	RMC-6291 is an orally active and covalent inhibitor of KRAS^G12C(ON). RMC-6291 forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA).
S2650	RN-1734	RN-1734 (TRPV4 Antagonist I) is a selective transient receptor potential vanilloid 4 (TRPV4) antagonist with IC50 of 2.3 μM, 5.9 μM and 3.2 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1734 alleviates demyelination and inhibits glial activation and the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.
E0031	RN-1747	RN-1747 is a selective TRPV4 agonist with EC50s of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 also antagonizes TRPM8 with IC50 of 4 μM.
E0346	Ro 20-1724	Ro 20-1724 is a potent inhibitor of PDE IV with Ki value of 3.1 μM and a potent gastric secretagogues.
S0007	RO 5028442 (RG7713)	RO 5028442 (RG7713) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM for hV1a and 39 nM for mV1a.
S8172	Ro 61-8048	Ro 61-8048 is a high-affinity kynurenine 3-hydroxylase (KMO) inhibitor with IC50 and K_i of 37 nM and 4.8 nM, respectively.
S7747	Ro-3306	RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with K_i of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis.
S0305	RO1138452	RO1138452 (CAY10441) is a potent and selective antagonist of IP (prostacyclin, PGI2) receptor with pKi of 9.3 and 8.7 in human platelets and a recombinant IP receptor system, respectively.
S7248	Ro3280	RO3280 (Ro5203280) is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
S1575	RO4929097	RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.
S0384	RO495	RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2).
S0372	RO4987655	RO4987655(RG 7167,CH4987655) is an allosteric MEK inhibitor with IC50 of 5 nM. RO4987655 exhibits a significant anti-proliferative and antitumor activity.
E1245	Ro5-3335	Ro5-3335 is an inhibitor of Core binding factor leukemia (CBF leukemia), by interacting with RUNX1 and CBFβ directly, repressing RUNX1/CBFB-dependent transactivation and runx1-dependent hematopoiesis.
E0960	RO5186582	RO5186582 (Basmisanil, RG1662) is a highly selective GABA_Aα5 negative allosteric modulator.
S0167	RO8994	RO8994 is a potent and selective small-molecule MDM2 inhibitor with IC50 values of 5 nM in HTRF binding assays and 20 nM in MTT proliferation assays, respectively.
S4876	Robenidine Hydrochloride	Robenidine Hydrochloride (Dexium, Nugatex, Rasexinium, Toraxine) is an anticoccidial agent mainly for poultry.
E0459	Robinetin	Robinetin inhibits HIV integrase cleavage and integration in a dose-dependent manne, inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus, also inhibits egg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency.
S8548	Roblitinib (FGF401)	Roblitinib (FGF401) is an FGFR4-selective inhibitor with an IC50 of 1.9 nM. It binds in a reversible covalent manner to the FGFR4 kinase domain and shows at least 1,000 fold selectivity against of panel of 65 kinases in biochemical assays.
S7428	Rocaglamide	Rocaglamide (Roc-A), isolated from Aglaia species, is a potent inhibitor of heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also inhibits NF-κB activity. Rocaglamide exhibits anti-tumor activity.
S7284	Rociletinib (CO-1686)	Rociletinib (CO-1686, AVL-301) is an irreversible, mutant-selective EGFR inhibitor with K_i of 21.5 nM and 303.3 nM for EGFR^L858R/T790M and EGFR^WT in cell-free assays, respectively. Phase 2.
S1397	Rocuronium Bromide	Rocuronium Bromide (ORG 9426) is a competitive AchR antagonist, used in modern anaesthesia.
S3043	Rofecoxib	Rofecoxib (MK-0966) is a COX-2 inhibitor with IC50 of 18 nM.
S2131	Roflumilast	Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.
S5476	Rolapitant	Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.
S1430	Rolipram	The PDE4 selective inhibitor, Rolipram, inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.
S3020	Romidepsin	Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.
A2050	Romosozumab(anti-sclerostin)	Romosozumab is a monoclonal antibody that binds to sclerostin (an inhibitor of the Wingless-related integration site (Wnt) signaling pathway). It is a new osteoanabolic drug, that simultaneously increases bone formation and decreases bone resorption.
S4062	Ronidazole	Ronidazole is an antiprotozoal agent.
S3189	Ropinirole HCl	Ropinirole (SKF-101468A) a selective dopamine D2 receptors agonist with K_i of 29 nM.
S5504	Ropivacaine	Ropivacaine is a member of the amino amide class of local anesthetics.
S4058	Ropivacaine HCl	Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
S9676	Ropsacitinib (PF-06826647)	Ropsacitinib (PF-06826647, Tyk2-IN-8, compound 10) is a selective and orally administered inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 17 nM for binding to TYK2 catalytically active JH1 domain. PF-06826647 (Tyk2-IN-8, compound 10) also inhibits JAK1 and JAK2 with IC50 of 383 nM and 74 nM, respectively. PF-06826647 (Tyk2-IN-8, compound 10) is used in the treatment of psoriasis (PSO).
S2307	Roquinimex	Roquinimex (FCF 89, Linomide, LS 2616) is a novel immunomodulator augmenting natural killer (NK) cell activity and T-lymphocyte related effector functions. Roquinimex is a potent oral active tumor antiangiogenic agent. Roquinimex inhibits the secretion of TNF-α.
E3112	Rosa Roxburghii Fruit Extract	Rosa Roxburghii Fruit Extract is extracted from the fruit of Rosa Roxburghii, which has the potential to prevent type 2 diabetes by regulating plasma metabolites and gut microbes.
E3113	Rosa Roxburghii Root Extract	Rosa Roxburghii Root Extract is extracted from the roots of Rosa Roxburghii, which is used for the treatment of abdominal pain, acute bacillary dysentery, gastroenteritis, and other diseases in humans and livestock.
S3287	Rosamultin	Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. that inhibits HIV-1 protease. Rosamultin has protective effects on H₂O₂-induced oxidative damage and apoptosis.
S3844	Rosavin	Rosavin, a cinnamyl alcohol glycoside found in the plant Rhodiola rosea, possesses antidepressant and anxiolytic activities.
S1153	Roscovitine	Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.
E3478	Rose Extract	Rose Extract is extracated from Rosa, which has skin whitening and anti-wrinkle activities.
E3477	Rose hip Extract	Rose Hip Extract is extracted from the fruits of Rosa L., which is used to treat kidney stones, gastro-enteric ailments, hypertension, and respiratory problems such as bronchitis, cough, and colds.
E3764	Rose Pelargonium Leaf Extract	Rose Pelargonium Leaf Extract is derived from the herb of Rose Pelargonium.
E3507	Rose-of-Sharon Seed Extract	Rose-Of-Sharon Seed Extract is extracted from the seeds of Hibiscus syriacus L., which is a nutritionally excellent food ingredient.
E3480	Rosemary Extract	Rosemary Extract is extracted from Salvia rosmarinus, which has bioactivities such as hepatoprotective, antifungal, insecticide, antioxidant, and antibacterial.
S2556	Rosiglitazone	Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.
S2075	Rosiglitazone HCl	Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
S2505	Rosiglitazone maleate	Rosiglitazone maleate, a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.
S3612	Rosmarinic acid	Rosmarinic acid (RA, Rosemary acid) is a naturally occurring hydroxylated compound. It has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling.
S2169	Rosuvastatin calcium	Rosuvastatin calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay.
S2348	Rotenone	Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron transport. Rotenone inhibits NADH/DB oxidoreductase and NADH oxidase with IC50 of 28.8 nM and 5.1 nM, respectively. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.
S4274	Rotigotine	Rotigotine(N-0923) is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.
S7862	Rottlerin	Rottlerin (Mallotoxin, NSC 56346, NSC 94525), a natural compound purified from Mallotus Philippinensis, is a specific Protein kinase inhibitor with IC50 of 3 μM, 6 μM and 5.3 μM for PKCδ(from baculovirus-infected Sf9 insect cells), PKCδ(from porcine spleen) and CaM kinase III, respectively. Rottlerin also inhibits PKCα, PKCγ, PKCβ, PKCη, CKII and PKA with IC50 of 30 μM, 40 μM, 42 μM, 82 μM, 30 μM and 78 μM, respectively.
S9514	Rotundic acid	Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways.
S2437	Rotundine	Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
S1007	Roxadustat (FG-4592)	Roxadustat (FG-4592) is an HIF-α prolyl hydroxylase inhibitor in a cell-free assay, stabilizes HIF-2 and induces EPO production. Roxadustat potentiates RSL3 induced ferroptosis. Phase 3.
S1880	Roxatidine Acetate HCl	Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.
S2506	Roxithromycin	Roxithromycin (Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin,RU-28965) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.
S3827	Royal jelly acid	Royal jelly acid (10-Hydroxy-trans-2-decenoic acid, 10H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysaccharide (LPS)- and interferon (IFN)-γ-stimulated macrophage responses, inhibition of T-cell proliferation and anti-rheumatoid activity.
E1175	RP-6306	RP-6306 is a Protein Kinase, Membrane Associated Tyrosine/Threonine 1 (PKMYT1) inhibitor, which can be used for the research of cancer.
S0820	RP-64477	RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.
E2682	RPI-1	RPI-1 inhibits proliferation of human papillary thyroid carcinoma cell line TPC-1 by inducing accumulation of cells at the G2 cell cycle phase, abolishes Ret/Ptc1 tyrosine phosphorylation along with its binding to Shc and phospholipase Cg, also abolishes the activation of JNK2 and AKT.
S8405	RRx-001	RRx-001 is a novel epigenetic modulator with potential radiosensitizing activity. It inhibits glucose 6-phosphate dehydrogenase(G6PD) in human tumor cells, binds hemoglobin and drives RBC-mediated redox reactions under hypoxia. RRx-001 triggers apoptosis and exhibits anticancer activity.RRx-001 is also a downregulator of the CD47- SIRPα checkpoint pathway.
S8234	RS-1	RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is an HDR(homology-directed repair) enhancer that enhances Cas9- and TALEN-mediated knock-in efficiency in rabbit embryos both in vitro and in vivo.
S7538	RS-102895 Hydrochloride	RS-102895 hydrochloride (HCl) is a potent antagonist of Chemokine (C-C motif) receptor 2 (CCR2) with IC50 of 360 nM, and shows no effect on CCR1. RS-102895 hydrochloride also inhibits human α1a and α1d receptors, rat brain cortex 5-HT1a receptor in cells with IC50s of 130 nM, 320 nM, 470 nM, respectively.
S2698	RS-127445	RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pK_i of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.
S3383	RS102895	RS 102895 is a small molecule antagonist of CCR2 with an IC50 of 360 nM.
S9738	RS504393	RS504393, an extremely selective CC chemokine receptor (CCR) 2 antagonist with IC50 of 98 nM, also targets multiple receptors for inhibition of CCR2b and CCR1 receptors when administrated in higher concentration.
S8155	RSL3	RSL3 ((1S,3R)-RSL3) is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.
S0470	RSV604	RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. RSV604 has significant potential for the effective treatment of RSV disease. Phase 2.
S0888	Rsva 405	Rsva 405, a novel small-molecule activator of AMPK, is a potent inhibitor of adipogenesis and thus may have therapeutic potential against obesity.
E0458	RTICBM-189	RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca²⁺ mobilization assay.
S0071	RU-301	RU-301 is a pan-TAM receptor (Axl, Tyro3 and Mertk) inhibitor that blocks the Axl receptor dimerization site with Kd of 12 μM and IC50 of 10 μM, respectively.
S6841	RU.521	RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.
S5285	RU58841	RU58841, also known as PSK-3841 or HMR-3841, is a non-steroidal anti-androgen.
E3210	Rubi Fructus Extract	Rubi Fructus Extract is extracted from Rubi Fructus, which has anti-tumor, antioxidant, and anti-inflammatory activities.
E0657	Rubiadin 1-methyl ether	Rubiadin-1-methyl ether, a natural anthraquinone compound isolated from the root of Morinda officinalis How, can inhibit osteoclastic bone resorption through blocking NF-κB pathway and may be a promising agent for the prevention and treatment of bone diseases characterized by excessive bone resorption.
S9162	Rubimaillin	Rubimaillin (Mollugin), found in the Chinese medical plant Rubia cordifola, is a dual inhibitor of acetyl-CoA cholesterol acyltransferase 1 (ACAT1) and acetyl-CoA cholesterol acyltransferase 2 (ACAT2), but is more selective for the ACAT2 isozyme.
S2288	Rubitecan	Rubitecan (9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000) is a topoisomerase I inhibitor extracted from the bark and leaves of the Camptotheca acuminata tree, which is native to China. Rubitecan is an oral camptothecin with antitumour activity.
S7663	Ruboxistaurin (LY333531) HCl	Ruboxistaurin (LY333531) HCl is a β-specific protein kinase C inhibitor. It competitively and reversibly inhibits PKCβ1 and PKCβ2 with IC50 values of 4.7 and 5.9 nM respectively.
S4948	Rucaparib	Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.
S5195	Rucaparib Camsylate	Rucaparib (Rubraca, AG014699, PF01367338) Camsylate is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains.
S1098	Rucaparib phosphate	Rucaparib phosphate is an inhibitor of PARP with K_i of 1.4 nM for PARP1 in a cell-free assay, also showing binding affinity to eight other PARP domains. Phase 3.
S1256	Rufinamide	Rufinamide (CGP 33101,E 2080,RUF 331,Banzel) is a voltage-gated sodium channel blocker, used an anticonvulsant medication.
E3704	Rumex madaio Makino Extract	Rumex Madaio Makino Extract is derived from Rumex madaio Makino (Polygonaceae), leaf and root tissues of which can be used as medicine such as clearing heat and detoxification, removing blood stasis, and defecating and killing insects.
S3052	Rupatadine Fumarate	Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with K_i of 550 nM and 102 nM, respectively.
S9183	Ruscogenin	Ruscogenin, a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been reported to exert significant anti-inflammatory and anti-thrombotic activities.
S2349	Rutaecarpine	Rutaecarpine (Rutecarpine) is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs; a new class of COX-2 inhibitor.
E2993	Ruthenium Red	Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye, which is a L-type calcium current (ICa) blocker. It is widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides.
S2350	Rutin	Rutin (Rutoside), a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.
S6264	Rutin hydrate	Rutin (Quercetin-3-O-rutinoside, Rutoside, Sophorin) is a glycoside found in a wide variety of plants including citrus fruit.
S1378	Ruxolitinib	Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.
S5243	Ruxolitinib Phosphate	Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.
S8199	Ruxotemitide (LTX 315)	Ruxotemitide (LTX 315) is the oncolytic peptide that kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.