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Catalog No.	Product Name	Information
S6104	(±)-α-Tocopherol	(±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage.
S6294	1,3,5-Trimethoxybenzene	1,3,5-Trimethoxybenzene (Phloroglucinol trimethyl ether, Sym-trimethoxybenzene, Trimethylphloroglucinol) is a potential biomarker of flavonoid intake in human. It is a human xenobiotic metabolite.
S5147	1,3,5-Trimethylpyrazole	1,3,5-Trimethylpyrazole (1,3,5-TMePz; 1,3,5-Trimethyl-1H-pyrazole) is an intermediate product used for chemical synthesis.
S6175	1,5,5-Trimethylhydantoin	1,5,5-Trimethylhydantoin is a chemical.
E2907	1-Thioglycerol	1-Thioglycerol(Mercaptopropanedioltech) is an inhibitor of glycerol kinase activity. It stimulates the synthesis of porphyrin in aerobically growing Escherichia coli.
S5172	1-Triacontanol	1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.
S4508	2,2,2-Tribromoethanol	2,2,2-Tribromoethanol (TBE, Tribromoethanol) is an organic compound used to anesthetize animals.
S6018	2,3,4-Trihydroxybenzoic acid	2,3,4-Trihydroxybenzoic acid is a phenol constituent of Pachysandra terminalis with antioxidant activity.
E1775	2,4-Thiazolidinedione	2,4-Thiazolidinedione (Thiazolidinedione), an insulin sensitizer, is a specific agonist of peroxisome proliferator-activated receptor (PPAR)γ. Thiazolidinedione treatment corrects impaired muscle insulin action in vivo.
S5613	2-Thiohydantoin	2-Thiohydantoin is a reactant for chemical synthesis.
S3100	2-Thiouracil	2-Thiouracil(Deracil,Thiouracil) is a thiolated uracil derivative that is a known antihyperthyroid agent.
S3888	3,4',5-Trimethoxy-trans-stilbene	3,4',5-Trimethoxy-trans-stilbene (MR-3) is a methylated derivative of resveratrol and shows more potent inhibitory effects on the growth of human cancer cells (HT-29, PC-3, COLO 205) with IC50 values of 81.31, 42.71 and 6.25 μM, respectively.
S4961	3,4,5-Trimethoxycinnamic acid	3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
S1912	3,6,9-Trioxaundecanedioic Acid	3,6,9-Trioxaundecanedioic acid is a PEG-based PROTAC linker that is applicable to the synthesis of PROTACs.
E4021	3-(Trimethoxysilyl)propyl methacrylate	3-(Trimethoxysilyl)propyl methacrylate (TMPSM) is a reactive monomer and silane coupling agent. It is widely used in thepreparation and fabrication of organic/inorganic hybrid nanomaterials.
S8628	3-TYP	3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor which is selective for Sirt3 over Sirt1 and Sirt2. The IC50 values for SITR1, SIRT2, SIRT3 are 88 nM, 92 nM, 16 nM respectively.
S0913	4',5,7-Trimethoxyflavone	4',5,7-Trimethoxyflavone (5,7,4'-Trimethoxyflavone, TMF) is a flavonoid isolated from Kaempferia parviflora (KP) that induces apoptosis. 4',5,7-Trimethoxyflavone increases sub-G1 phase, DNA fragmentation, annexin-V/PI staining and Bax/Bcl-xL ratio, activates caspase-3 and degrades poly (ADP-ribose) polymerase (PARP) protein.
E1292	4-Thiouridine	4-thiouridine (4-Thio-UTP), a thiouridine and a nucleoside analogue, has a role as an affinity label and an antimetabolite.
S9328	5,6,7-Trimethoxyflavone	5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
S7757	6-Thio-dG	6-thio-dG (β-TGdR) is a nucleoside analog and telomerase substrate.
E2402	T-1101 tosylate	T-1101 tosylate (TAI-95 tosylate) is a Hec1/Nek2 (Highly expressed in cancer 1 / NIMA-related kinase 2) inhibitor with antitumor activity.
S0341	T-26c	T-26c is a highly potent and selective inhibitor of matrix metalloproteinase-13 (MMP-13) with IC50 of 6.9 pM, more than 2600-fold selectivity over other related metalloenzymes.
S8438	T-3775440 HCl	T-3775440 HCl is an irreversible LSD1 inhibitor that is highly selective for LSD1 relative to other monoamine oxidases (e.g., MAO-A and MAO-B), with an IC50 value of 2.1 nmol/L.
S8966	T-5224	T-5224 is a selective inhibitor of transcription factor c-Fos/activator protein (AP)-1 with anti-inflammatory effects. T-5224 specifically inhibits the DNA binding activity of c-Fos/c-Jun and the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription.
S2871	T0070907	T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.
S7076	T0901317	T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of 20nM for LXRα and 5 μM for FXR, respectively. T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM, respectively. T0901317 significantly suppresses cell proliferation and induces apoptosis.
E1429	T1-44	T1-44 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5). It exhibits anti-tumor activity in pancreatic cancers.
S1203	T16Ainh-A01	T16Ainh-A01 is a potent and selective inhibitor of calcium-activated chloride channel (CaCC)/transmembrane protein 16A (TMEM16A, ANO1) with IC50 of 1.8 μM.
S5726	T3 (Triiodothyronine)	T3 (Triiodothyronine) is a thyroid hormone that affects various physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.This product is soluble but easy to precipitate after freezing in DMSO. 0.1 M NaOH is recommended as a stock solution.
S6498	T56-LIMKi	T56-LIMKi is a selective inhibitor of LIMK2.
S0359	T863 (DGAT-3)	T863 (DGAT-3) is a potent, selective and orally active inhibitor of Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) tht acts on the acyl-CoA binding site of DGAT1 and inhibits DGAT1-mediated triacylglycerol formation in cells.
S0186	TA-01	TA-01 is a potent inhibitor of CK1δ/ε and p38 MAPK with IC50 of 6.4 nM, 6.8 nM and 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.
S6807	TA-02	TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM. TA-02 especially inhibits TGFBR-2.
S2818	Tacedinaline (CI994)	Tacedinaline (CI994, PD-123654, GOE-5549, Acetyldinaline) is a selective class I HDAC inhibitor with IC50 of 0.9, 0.9, 1.2, and >20 μM for human HDAC 1, 2, 3, and 8, respectively. Phase 3.
S4357	Tacrine HCl	Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist. Tacrine hydrochloride hydrate is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.
S3639	Tacrine hydrochloride hydrate	Tacrine (Tetrahydroaminacrine, Tetrahydroaminoacridine) is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It also acts as a histamine N-methyltransferase inhibitor.
S5003	Tacrolimus (FK506)	Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.
S1512	Tadalafil	Tadalafil is a PDE-5 inhibitor with IC50 of 1.8 nM in a cell-free assay. Tadalafil is at least 9000 times more selective for PDE5 than most of the other families of PDEs, with the exception of PDE11. It can partial inhibits PDE11
A3065	Tadocizumab (Anti-Integrin a2b3 (ITGA2 & ITGB3))	Tadocizumab (Anti-Integrin a2b3 (ITGA2 & ITGB3)) is a humanized monoclonal antibody tageting integrin αIIbβ3. It has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research. MW :145.3 KD.
S2820	TAE226 (NVP-TAE226)	TAE226 (NVP-TAE226) is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2, ~10- to 100-fold less potent against InsR, IGF-1R, ALK, and c-Met. TAE226 (NVP-TAE226) induces apoptosis.
S1108	TAE684 (NVP-TAE684)	TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor which blocked the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM, 100-fold more sensitive for ALK than InsR. TAE684 (NVP-TAE684) induces cell cycle arrest and apoptosis.
S6465	Tafamidis	Tafamidis is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs.
E2665	Tafenoquine	Tafenoquine (WR 238605) is an 8-aminoquinoline, used as an anti-malarial prophylactic agent.
S4851	Tafluprost	Tafluprost (AFP-168,MK2452) is a novel prostaglandin analog with a high affinity for the fluoroprostaglandin (FP) receptor PGF2α. A prostanoid selective FP receptor agonist.
S9878	Tagtociclib (PF-07104091)	Tagtociclib (PF-07104091) inhibits CDK2, which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.
S8459	TAK-063	TAK-063 (Balipodect) is a novel and selective phosphodiesterase 10A(PDE10A) inhibitor with an IC50 of 0.30 nM.
S8341	TAK-243 (MLN7243)	TAK-243 (MLN7243) is a potent, mechanism-based small-molecule inhibitor of the ubiquitin activating enzyme (UAE) with an IC50 of 1 ± 0.2 nM in the UBCH10 E2 thioester assay. It has minimal inhibitory activity in a panel of kinase and receptor assays, as well as on human carbonic anhydrase type I and type II. TAK-243 (MLN7243) induces ER stress, abrogates NFκB pathway activation and promotes apoptosis.
S2784	TAK-285	TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
S7291	TAK-632	TAK-632 is a potent pan-Raf inhibitor with IC50 of 8.3 nM and 1.4 nM for B-Raf(wt) and C-Raf in cell-free assays, respectively, showing less or no inhibition against other tested kinases.
S8442	TAK-659	TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
S2928	TAK-715	TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. Phase 2.
S2617	TAK-733	TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1.
S2718	TAK-901	TAK-901 is a novel inhibitor of Aurora A/B with IC50 of 21 nM/15 nM. It is not a potent inhibitor of cellular JAK2, c-Src or Abl. Phase 1.
S1239	TAK-960	TAK-960 is a novel, investigational, orally bioavailable, potent, and selective PLK1 inhibitor that has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1).
S8663	Takinib	Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib induces apoptosis.
S8455	Talabostat (PT-100)	Talabostat (Val-boroPro, PT-100) is a dipeptidyl peptidase inhibitor with IC50 values of <4 nM, 4 nM, 11 nM, 310 nM, 560 nM and 390 nM for DPP-IV, DPP8, DPP9, QPP, FAP and PEP respectively. It has antineoplastic and hematopoiesis- stimulating activities.
S2157	Taladegib (LY2940680)	Taladegib (LY2940680) binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling. Phase 1/2.
S9223	Talatisamine	Talatisamine, a delphinine type alkaloid extracted from Aconitum talassicum, is a newly identified K+ channel blocker with hypotensive and antiarrhythmic activities.
S7048	Talazoparib (BMN 673)	Talazoparib (BMN 673, LT-673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.
S1900	Talc	Talc is a mineral composed of hydrated magnesium silicate with the chemical formula H2Mg3(SiO3)4 or Mg3Si4O10(OH)2.
S8901	Taletrectinib (DS-6051b)	Taletrectinib (DS-6051b, AB-106) is a new-generation selective ROS1/NTRK inhibitor with ic50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM for ROS1,NTRK1,NTRK2 and NTRK3,respectively.
E3703	Talinum paniculatum Extract	Talinum Paniculatum Extract is derived from Talinum paniculatum (Jacq.) Gaertn. (Talinaceae), which is a Brazilian Cerrado plant used in traditional medicine and as a food source with diuretic effects.
S6439	Talniflumate	Talniflumate (MSI-1995) is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma. Talniflumate is also an inhibitor of human calcium-activated chloride channels.
E3440	Tamarindus indica seed Extract	Tamarindus indica seed Extract is extracted from the seeds of Tamarindus indica, which helps to reduce inflammation and inflammation-induced cartilage degeneration.
E2502	Tamarixetin	Tamarixetin (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin and has superior anti-inflammatory properties in bacterial sepsis by increasing the population of IL-10-secreting immune cells.
S2225	TAME	Tosyl-L-Arginine Methyl Ester (TAME) is an APC inhibitor.
S4260	Tamibarotene	Tamibarotene(Am 80) is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.
S8933	Tamnorzatinib (ONO-7475)	Tamnorzatinib (ONO-7475) is a potent, selective, and orally active novel inhibitor of Anexelekto(Axl)/MER tyrosine kinase with IC50 of 0.7 nM and 1.0 nM for AXL and MER, respectively. ONO-7475 suppresses the emergence and maintenance of tolerant cells to the initial EGFR-TKIs, osimertinib or dacomitinib, in AXL-overexpressing EGFR-mutated NSCLC cells. ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells.
S1238	Tamoxifen	Tamoxifen is an orally active, selective estrogen receptor modulator (SERM) which exhibits both estrogenic agonist and antagonist effects. It blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity.
S1972	Tamoxifen Citrate	Tamoxifen Citrate is a selective estrogen receptor modulator (SERM). Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen induces apoptosis and autophagy.
S1435	Tamsulosin hydrochloride	Tamsulosin (Flomax) hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.
E2356	Tandospirone	Tandospirone (SM-3997), a potent and selective 5-HT1A receptor partial agonist, with a Ki of 27 nM, has anxiolytic and antidepressant activities.
S1043	Tandutinib (MLN518)	Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2.
S1141	Tanespimycin (17-AAG)	Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3.
S2363	Tangeretin	Tangeretin (Tangeritin), a natural polymethoxylated flavone concentrated in the peel of citrus fruits, is known to have antiproliferative, antiinvasive, antimetastatic and antioxidant activities.
S3951	Tannic acid	Tannic acid (Gallotannic acid), a polyphenolic compound, is a CXCL12/CXCR4 inhibitor with antiangiogenic, anti-inflammatory and antitumor activity.
S2364	Tanshinone I	Tanshinone I, an active principle isolated from Salvia miltiorrhiza (Danshen), is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells.
S2365	Tanshinone IIA	Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor.
S3766	Tanshinone IIA sulfonate sodium	Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA isolated as the main pharmacologically active natural compound from a traditional Chinese herbal medicine, the dried root of Salvia miltiorrhiza Bunge known as Danshen. Sodium tanshinone IIA sulfonate (STS) is a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium tanshinone IIA sulfonate (STS) inhibits the activity of CYP3A4 and store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC).
S8490	Tanzisertib(CC-930)	Tanzisertib (CC-930, JNK-930, JNKI-1) is kinetically competitive with ATP in the JNK-dependent phosphorylation of the protein substrate c-Jun and potent against all isoforms of JNK (Ki(JNK1) = 44 ± 3 nM, IC50(JNK1) = 61 nM, Ki(JNK2) = 6.2 ± 0.6 nM, IC50(JNK2) = 5 nM, IC50(JNK3) = 5 nM) and selective against MAP kinases ERK1 and p38a with IC50 of 0.48 and 3.4 μM respectively.
S7434	TAPI-1	TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. TAPI-1 is also an inhibitor of Matrix Metalloproteinase (MMP).
S9700	Tapinarof	Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.
S0111	Taprenepag	Taprenepag(CP-544326) is a potent and selective prostaglandin EP2 agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively.
A2389	Tarextumab (Anti-NOTCH3)	Tarextumab (Anti-NOTCH3) is an anti-Notch2/3 fully human IgG2 monoclonal antibody with anti-tumor activity. MW: 145.5 kD.
S8028	Tariquidar	Tariquidar is a potent and selective noncompetitive inhibitor of P-glycoprotein with K_d of 5.1 nM in CHrB30 cell line, reverses drug resistance in MDR cell Lines. Phase 3.
S6233	Tartaric acid	Tartaric acid (2,3-Dihydroxysuccinic acid, Threaric acid, Racemic acid, Uvic acid, Paratartaric acid, Winestone) is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes. It has several applications for industrial and pharmaceutical use.
E3395	Tartary buckwheat Extract	Tartary buckwheat Extract is extracted from Tartary buckwheat, which has bioactive functions such as anti-oxidation, hypocholesterolaemia, and anti-inflammation.
S8539	TAS-102	TAS-102 (Trifluridine-Tipiracil Hydrochloride Mixture) is an orally administered combination of a thymidine-based nucleic acid analogue, trifluridine, and a thymidine phosphorylase inhibitor, tipiracil hydrochloride.
S9741	TAS-119	TAS-119 is a potent, selective, and orally active inhibitor of Aurora A, including Aurora B with an IC50 of 1.0 nM and 95 nM, respectively. It exhibits antitumor activities.
S6424	TAS-301	TAS-301 is an inhibitor of smooth muscle cell migration and proliferation. TAS-301 inhibits intimal thickening after balloon injury to rat carotid arteries, and inhibits PKC activation induced by PDGF.
S8833	TAS0728	TAS0728 (TPC 107) is a potent, selective, orally active, irreversible and covalent-binding inhibitor of HER2 (human epidermal growth factor receptor 2) with IC50 of 13 nM. TAS0728 inihibits BMX, HER4, BLK, EGFR, JAK3, SLK, LOK and human HER2 with IC50 of 4.9 nM, 8.5 nM, 31 nM, 65 nM, 33 nM, 25 nM, 86 nM and 36 nM, respectively. TAS0728 shows antitumor activity.
S8849	TAS4464	TAS4464 is a potent and highly selective NEDD8 activating enzyme (NAE) inhibitor with IC50 of 0.955 nM. TAS4464 exhibits superior antitumor activity with prolonged target inhibition.
S7103	Taselisib (GDC 0032)	Taselisib (GDC 0032, RG7604) is a potent, next-generation β isoform-sparing PI3K inhibitor targeting PI3Kα/δ/γ with K_i of 0.29 nM/0.12 nM/0.97nM, >10 fold selective over PI3Kβ.
S4281	Tasimelteon	Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively).
S7326	Tasisulam	Tasisulam (LY573636) is an antitumor agent and an apoptosis inducer via the intrinsic pathway. Phase 3.
S7617	Tasquinimod	Tasquinimod (ABR-215050) is an orally active antiangiogenic agent by allosterically inhibiting HDAC4 signalling. Phase 3.
S8595	Tat-beclin 1 (Tat-BECN1)	Tat-beclin 1 (Tat-BECN1), a peptide known to stimulate autophagy through mobilization of endogenous Beclin 1, induces autophagy in vitro and in vivo and improves clinical outcomes.
P1220	tat-nr2b9c	Tat-NR2B9c (Tat-NR2Bct, NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively, and disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively, also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.
S2008	Taurine	Taurine is an organic acid widely distributed in animal tissues.
S3865	Taurochenodeoxycholic acid	Taurochenodeoxycholic acid (Taurochenodeoxycholate, TCDCA, Chenodeoxycholyltaurine), a bile acid formed in the liver of most species, is used as a cholagogue and choleretic.
E0154	Taurocholic acid sodium salt	Taurocholic acid sodium salt (Sodium Taurocholate, TANa) is a sodium salt of taurocholic acid and occurs in the bile of mammals. Taurocholic acid is used as a cholagogue and choleretic.
S5130	Taurocholic acid sodium salt hydrate	Taurocholic acid (Sodium taurocholate hydrate), a bile salt formed in the liver, is the product of conjugation of cholic acid with taurine that is involved in the emulsification of lipids. Its sodium salt is the chief ingredient of the bile of carnivorous animals.
E2411	Taurodeoxycholic acid sodium hydrate	Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. It activates S1PR2 pathway in addition to the TGR5 pathway.
S4885	Taurolidine	Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.
S3654	Tauroursodeoxycholic Acid (TUDCA)	Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA) and acts as a mitochondrial stabilizer and anti-apoptotic agent in several models of neurodegenerative diseases, including AD, Parkinson's diseases (PD), and Huntington's diseases (HD).
S4996	Tavaborole (AN-2690)	Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S2366	Taxifolin (Dihydroquercetin)	Taxifolin, type I inhibitor for VEGFR-2 kinase, is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
S3295	Taxifolin 7-rhamnoside	Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside), a flavonoid isolated from Hypericum japonicum, shows antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
E3282	Taxus Cuspidata Extract	Taxus Cuspidata Extract is extracted from Taxus Cuspidata, which has antibiotic, antioxidant, anticancer, and antiaging effects.
S1569	Tazarotene	Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.
S7128	Tazemetostat (EPZ-6438)	Tazemetostat (EPZ-6438, E7438) is a potent, and selective EZH2 inhibitor with K_i and IC50 of 2.5 nM and 11 nM in cell-free assays, exhibiting a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other HMTs.
S3077	Tazobactam	Tazobactam (Tazobactam acid, Tazobactamum) is a β-lactamases Inhibitor with antibacterial activity. It also inhibits the class D oxacillinase OXA-2. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect.
E0167	Tazobactam Sodium	Tazobactam (Tazobactam acid, Tazobactamum) Sodium is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms.
S6602	TB5	TB5 is a potent and selective MAO-B inhibitor with Ki values of 110 and 1,450 nM for MAO-B and MAO-A, respectively.
E2505	TBAP-001	TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-Raf kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay.
S4990	TBHQ	Tert-butylhydroquinone (TBHQ) is an antioxidant compound which is used to prevent lipid peroxidation and shows multiple cytoprotective actions. It is an activator of Nrf2.
S0425	TBK1/IKKε-IN-2	TBK1/IKKε-IN-2 (Ikk epsilon-in-1, IKKε-IN-1, MDK10496) is a dual inhibitor of TBK1 and IKKε.
S8922	TBK1/IKKε-IN-5	TBK1/IKKε-IN-5 (compound 1) is a dual inhibitor of TANK-binding kinase 1 (TBK1) and IκB kinase-ε (IKKε/IKK-i) with IC50 of 1.0 nM and 5.6 nM for TBK1 and IKKε, respectively. TBK1/IKKε inhibition enhances response to PD-1 blockade, which effectively predicts tumor response in vivo.
S0978	TBOPP	TBOPP is a selective inhibitor of dedicator of cytokinesis (DOCK1, Dock180) that inhibits DOCK1-mediated Rac activation with IC50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with Kd of 7.1 μM. TBOPP exhibits anti-tumor activity.
E0613	TC-067533	TC-067533 is a potent SARS-CoV papain-like protease (PLpro) inhibitor with an IC50 of 8.7 μM.
E1120	TC-DAPK 6	TC-DAPK 6 is a potent, ATP-competitive, and highly selective DAPK inhibitor with IC50 of 69 and 225 nM against DAPK1 and DAPK3, respectively.
S0855	TC-E 5003	TC-E 5003 (NSC 30176, Compound 2e) is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) with IC50 of 1.5 μM. TC-E 5003 modulates the lipopolysaccharide (LPS)-induced AP-1 and NF-κB signaling pathways and can possibly be further developed as an anti-inflammatory compound.
S6759	TC-G-1008 (GPR39-C3)	TC-G-1008 (GPR39-C3) is a potent and orally bioavailable agonist of GPR39 with EC50 of 0.4nM and 0.8nM for rat and human receptor, respectively.
S6738	TC-H 106	TC-H 106 (Pimelic Diphenylamide 106) is a slow, tight-binding inhibitor of class I histone deacetylases(HDAC) with Ki value of 148 nM, about 102 nM, 14 nM for HDAC1, HDAC2, HDAC3, respectively.
S6976	TC-O 9311	TC-O 9311 is a potent orphan G protein-coupled receptor 139 (GPR139) agonist with an EC50 of 39 nM.
E1618	TC-S 7009	TC-S 7009 is a potent and selective inhibitor of HIF-2α with a Kd value of 81 nM. TC-S 7009 is more selective for HIF-2α than HIF-1α. It disrupts HIF-2α heterodimerization, decreases DNA-binding activity, and reduces HIF-2α target gene expression.
S4611	TCEP Hydrochloride	TCEP (Tris(2-carboxyethyl)phosphine) hydrochloride, a non-thiol reducing agent, promotes NF-κB-DNA binding in a dose-related manner.Solutions are best fresh-prepared.
S7140	TCID	TCID is a DUB inhibitor for ubiquitin C-terminal hydrolase L3 with IC50 of 0.6 μM, 125-fold selective to L1.
S0446	TCN 201	TCN-201 is a selective GluN1/GluN2A (NR1/NR2A) NMDA receptor antagonist with pIC50 6.8 for NR1/NR2A and <4.3 for NR1/NR2B (GluN1/GluN2B),respectively.
S6895	TCPOBOP	TCPOBOP is a constitutive androstane receptor (CAR) agonist. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins.
E2697	TCPP	TCPP (Tris(2-chloroethyl) phosphate) is a pervasive flame retardant.
S1050	TCS PIM-1 1	TCS PIM-1 1 (SC 204330) is a potent and selective inhibitor of ATP-competitive Pim-1 kianse with IC50 of 50 nM, shows good selectivity over Pim-2 and MEK1/MEK2 with IC50 > 20000 nM.
S6717	TCS-OX2-29	TCX-OX2-29 is a OX2R antagonist (pKi = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (IC50s = 40 nM and >10,000 nM, respectively).
S1451	TCS7010 (Aurora A Inhibitor I)	TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B. Aurora A Inhibitor I (TC-S 7010) triggers apoptosis through the ROS-mediated UPR signaling pathway.
S6994	TD-165	TD-165 is a PROTAC-based cereblon (CRBN) degrader. TD-165 comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group.
E1314	TDI-011536	TDI-011536 is a potent Lats kinase inhibitor that interrupts Hippo-Yap signaling and promotes proliferation of lesioned cardiac muscle cells.
S2926	TDZD-8	TDZD-8 (NP 01139) is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.
S5104	Tea polyphenol	Tea polyphenols are chemical compounds such as flavanoids and tannins found naturally in tea. Several biological properties have been associated to tea polyphenols (TP), including antioxidant, anti-carcinogenic and antimicrobial activities.
E3081	Tea Seed Extract	Tea Seed Extract is extracted from Camellia oleifera, which has effective anti-tumor activity.
S2159	Tebipenem Pivoxil	Tebipenem pivoxil (L-084, ME1211,TBPM-PI,LJC 11036) is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.
S3380	Tecovirimat	Tecovirimat is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infection.
S3256	Tectochrysin	Tectochrysin (Techtochrysin, NSC 80687) is one of the major flavonoids of Alpinia oxyphylla Miquel. Tectochrysin significantly increases the expression of DR3, DR4 and Fas and inhibits activity of NF-κB. Tectochrysin induces apoptotic cell death.
S3818	Tectoridin	Tectoridin (Shekanin), an isoflavone isolated from flowers of Pueraria thunbergiana, has several pharmacological effects including anti-cancer, anti-inflammatory, antioxidant, and hepatoprotectivy.
S9122	Tectorigenin	Tectorigenin (TEC) is an isoflavone isolated from various medicinal plants, such as Pueraria thunbergiana Benth, Belamcanda chinensis, and Iris unguicularis. It has been reported to exert pharmacological actions, including antitumor and antibacterial effects, free radical neutralization, and selective estrogen receptor modulation.
S8951	TED-347	TED-347 is a potent, irreversible, covalent and allosteric inhibitor of the TEAD⋅Yap protein-protein interaction. TED-347 inhibits TEAD4⋅Yap1 protein-protein interaction with an apparent EC50 of 5.9 μM.
S5278	Tedizolid	Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
S4641	Tedizolid Phosphate	Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.
S9935	Teduglutide	Teduglutide (ALX-0600, Gattex, Revestive, TAK 633) is an analogue of human glucagon-like peptide-2 (GLP-2) and binds to the GLP-2 receptors. Teduglutide prolongs the intestinotrophic properties of GLP-2 in animal models.
E1554	Tefinostat(CHR-2845)	Tefinostat(CHR-2845) is a monocyte/macrophage-targeted inhibitor of pan-histone deacetylase (HDAC). Tefinostat undergoes cleavage mediated by the intracellular esterase human carboxylesterase-1 (hCE-1) to yield the active acid CHR-2847. In vitro studies reveal a specific heightened sensitivity of monocytoid leukemias to tefinostat.
S1300	Tegafur (FT-207)	Tegafur (NSC 148958,Fluorafur,FT-207) is a substance being used in the treatment of some types of cancer.
S5401	Tegaserod Maleate	Tegaserod Maleate(HTF-919) is a hydrogen maleate salt form of tegaserod, which is a 5-HT4 receptor partial agonist and binds with high affinity to 5-HT4 receptors. It has limited affinity for 5-HT1 receptors and no appreciable affinity for other 5-HT receptors, muscarinic, adrenergic, dopaminergic or opiate receptors.
S0733	Tegatrabetan (BC-2059)	Tegatrabetan (BC2059,Tegavivint) is an antagonist of β-Catenin. Tegatrabetan (BC2059) treatment disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1) and proteasomal degradation and declines in the nuclear levels of β-catenin.
S3395	Tegobuvir	Tegobuvir (TGV, GS 333126, GS-9190) is a non-nucleoside inhibitor of HCV RNA replication with proven antiviral activity in HCV-infected patients.
E0054	Tegoprazan	Tegoprazan (CJ-12420, IN-A001, K-CAB, LXI-15028, RQ-00000004) is a novel potent and highly selective inhibitor of gastric H+/K+-ATPase with IC50s ranging from 0.29 μM to 0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro, respectively.
S1399	Teicoplanin	Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.
S7739	Telacebec	Telacebec is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.
S7655	Telaglenastat (CB-839)	Telaglenastat (CB-839) is a potent, selective, and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC. CB-839(Telaglenastat) inudces autophagy and has antitumor activity. Phase 1.
S1538	Telaprevir	Telaprevir is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.
S2231	Telatinib	Telatinib (BAY 57-9352) is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRα with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively. Phase 2.
S1651	Telbivudine	Telbivudine(NV 02B) is a potent, and selective HBV reverse transcriptase inhibitor, used to treat HBV infection.
A2467	Telisotuzumab (Anti-HGFR / c-Met)	Telisotuzumab (Anti-HGFR / c-Met) is a monoclonal antibody that targets c-Met. MW: 145.64 KD.
D4046	Telisotuzumab vedotin	Telisotuzumab vedotin (Teliso-V, ABBV-399) is an antibody-drug conjugate (ADC) composed of the anti–c-Met humanized monoclonal antibody coupled to the cytotoxic monomethyl auristatin E (MMAE) through a mc-val-cit-PABC type linker. Telisotuzumab vedotin can be used for research on advanced solid tumours.
S3004	Telithromycin	Telithromycin is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity.
S1738	Telmisartan	Telmisartan (BIBR 277) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.
S2173	Telotristat Etiprate (LX 1606 Hippurate)	Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Phase 3.
S9623	Telratolimod	Telratolimod (3M-052, MEDI9197) is an agonist of toll-like receptor 7 (TLR-7) and toll-like receptor 8 (TLR-8) with antitumor activity.
S2100	Temocapril	Temocapril (CS-622,temocaprilum) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
S2099	Temocapril HCl	Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
E4467	Temozolomide Acid	Temozolomide acid is a carboxylic acid derivative of Temozolomide. It has an anticancer activity by causing breaks in DNA double strand, cell cycle arrest, and eventually cell death.
S2910	Tempol	Tempol (4-Hydroxy-TEMPO) is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Phase 2.
S6625	Temsavir (BMS-626529)	Temsavir (BMS-626529) is a novel small-molecule HIV-1 attachment inhibitor active against both CCR5- and CXCR4-tropic viruses.
S1044	Temsirolimus	Temsirolimus is a specific mTOR inhibitor with IC50 of 1.76 μM in a cell-free assay. Temsirolimus induces autophagy and apoptosis.
S8534	Temuterkib (LY3214996)	Temuterkib (LY3214996) is a selective and novel ERK1/2 inhibitor with IC50 of 5 nM for both enzymes in biochemical assays. It potently inhibits cellular phospho-RSK1 in BRAF and RAS mutant cancer cell lines.
S8545	TEN-010 (RG6146,Ro-6870810,(S)-JQ-35)	TEN-010 (RG6146, Ro-6870810,(S)-JQ-35) is an inhibitor of the Bromodomain and Extra-Terminal(BET) family bromodomain-containing proteins with potential antineoplastic activity.
S8672	Tenalisib	Tenalisib is a potent and selective dual PI3Kδ/γ inhibitor with IC50 values of 24.5 nM and 33.2 nM for PI3Kδ and PI3Kγ, respectively. Its selectivity over α and β isoforms are more than 300-fold and 100-fold, respectively.
S4212	Tenatoprazole	Tenatoprazole (TU-199,STU-Na) is a prodrug of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM. Tenatoprazole labels only the gastric H(+),K(+)-ATPase alpha-subunit, approximately 2.6 nM/mg of tenatoprazole is bound to the H(+),K(+)-ATPase.
S4636	Teneligliptin hydrobromide	Teneligliptin (Teneligliptin hydrobromide anhydrous) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM.
S1787	Teniposide	Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).
S1401	Tenofovir	Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.
S7856	Tenofovir Alafenamide	Tenofovir Alafenamide is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.
S4428	Tenofovir alafenamide fumarate	Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
S4427	Tenofovir alafenamide hemifumarate	Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection.
S5959	Tenofovir Disoproxil	Tenofovir Disoproxil (Bis(POC)-PMPA, GS 4331) is a prodrug of tenofovir, which is metabolised intracellularly to its active anabolite tenofovir diphosphate, a competitive inhibitor of HIV-1 reverse transcriptase and terminates the growing DNA chain.
S1400	Tenofovir Disoproxil Fumarate	Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.
S4879	Tenofovir hydrate	Tenofovir (GS-1278) hydrate blocks reverse transcriptase and hepatitis B virus infections.
S8000	Tenovin-1	Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 is also an inhibitor of dihydroorotate dehydrogenase (DHODH).
S2176	Tenovin-3	Tenovin-3 is an inhibitor of SIRT2. Tenovin-3 is able to increase p53 levels in MCF-7 cells.
S4900	Tenovin-6	Tenovin-6 is a small molecule activator of p53 transcriptional activity and inhibits dihydroorotate dehydrogenase (DHODH). Tenovin-6 is also an inhibitor of SirT1 and SirT2.
S2512	Tenoxicam	Tenoxicam(Ro-12-0068) is a good HO. radicals scavenger with an IC50 of 56.7 μM.
S9087	Tenuifolin	Tenuifolin, a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.
S0926	Tenuifoliside A	Tenuifoliside A isolated from Polygala tenuifolia, has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits its neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells.
S7067	Tepotinib	Tepotinib is a potent and selective c-Met inhibitor with IC50 of 4 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib (EMD 1214063) induces autophagy. Phase 1.
S7302	TEPP-46 (ML265)	TEPP-46 (ML265, CID-44246499, NCGC00186528) is a potent activator of PKM2 in both biochemical (AC50 = 92 nM) and cell-based assays with high selectivity over PKM1, PKR and PKL.
S5006	Teprenone	Teprenone, an acylic polyisoprenoid, that is known as tetraprenylacetone or geranylgeranylacetone, is an anti-ulcer drug, clinically used for gastritis. Teprenone(Geranylgeranylacetone) is an inducer of heat shock proteins (HSPs) expression.
A2455	Teprotumumab (Anti-IGF-1R / CD221)	Teprotumumab (Anti-IGF-1R / CD221) is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab can be used for thyroid-associated ophthalmopathy research.MW: 145.5 KD.
S4679	Terazosin HCl	Terazosin (Hytrin, Zayasel, Terazosine, Flumarc, Fosfomic, Blavin) is a selective alpha-1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.
S2059	Terazosin HCl Dihydrate	Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).
S1725	Terbinafine	Terbinafine (SF 86-327,TDT 067) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
S2557	Terbinafine HCl	Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride) inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.
S4127	Terbutaline Sulfate	Terbutaline Sulfate(Terbutaline hemisulfate) is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.
S5033	Terconazole	Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470) is a new, broad-spectrum, triazole antifungal agent which is primarily used to treat vaginal fungal infections.
S6251	Terephthalic acid	Terephthalic acid (para-Phthalic acid, 1,4-Benzenedioic acid), a raw material for polyethylene terephthalate (PET) production, is one of the most important chemicals in petrochemical industry.
E2655	Terevalefim	Terevalefim (ANG-3777), a small molecule hepatocyte growth factor (HGF) mimetic, induces c-MET dimerization and phosphorylation, reducing apoptosis and increasing cellular proliferation.
S4353	Terfenadine	Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform. Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
S4169	Teriflunomide	Teriflunomide (A77 1726, HMR-1726) is the active metabolite of leflunomide, inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase, used as an immunomodulatory agent.
P1033	Teriparatide Acetate	Teriparatide Acetate is a recombinant form of parathyroid hormone, used in the treatment of some forms of osteoporosis
P1034	Terlipressin Acetate	Terlipressin Acetate is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.
E3254	Terminalia Chebula Extract	Terminalia Chebula Extract is extracted from Terminalia Chebula, which has antioxidant, hepatoprotective, neuroprotective, cytotoxic, antidiabetic, and anti-inflammatory activities.
E3473	Ternate buttercup root Extract	Ternate Buttercup Root Extract is extracted from the roots of Ternate Buttercup, which boosts the activity of the immune system, reduces inflammation, scavenges damaging particles known as free radicals, and destroys cancerous cells.
S4577	Terpin hydrate	Terpin hydrate is an expectorant, commonly used to loosen mucus in patients presenting with acute or chronic bronchitis, and related conditions.
S6118	Terpinen-4-ol	Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.,
S5691	Terpinyl Acetate	Terpinyl Acetate (alpha-Terpinyl), a naturally occuring compound found in several essential oils, is a flavouring agent.
S1814	tert-Butyl 11-aminoundecanoate	tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker that refers to the PEG composition. tert-Butyl 11-aminoundecanoate is applicable to the synthesis of a series of PROTACs.
E0016	Tertiapin-Q	Tertiapin-Q (TPNQ) is a derivative of tertiapin and inhibits BK-type K+ channels in a use- and concentration-dependent manner. Tertiapin-Q also binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with Ki values of 1.3 nM and 13.3 nM respectively.
E1189	TES-1025	TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13 nM.
S1789	Tetrabenazine (Xenazine)	Tetrabenazine(Xenazine,Ro 1-9569) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2; Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2.
S2573	Tetracaine HCl	Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
S4490	Tetracycline	Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.
S2574	Tetracycline HCl	Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.
S6344	Tetradecanedioic acid	Tetradecanedioic acid (Tetradecanedicarboxylate) is a C14 dicarboxylic acid.
E3730	Tetradium ruticarpum fruits Extract	Tetradium Ruticarpum Fruits Extract is obtained from the dried and nearly ripe fruits of Tetradium ruticarpum (A. Juss.) T.G. Hartley, which have long been used in treating headache and gastrointestinal disorders in oriental medicine.
S6284	Tetraethylammonium bromide	Tetraethylammonium bromide (TEAB, TEA bromide) is used as the source of tetraethylammonium ions in pharmacological and physiological studies, but is also used in organic chemical synthesis. It blocks selective potassium channels.
S4489	Tetraethylammonium chloride	Tetraethylammonium (TEA) chloride is a nonspecific potassium channel blocker with antitumor properties.
S5153	Tetrahydroberberine	Tetrahydroberberine (Canadine) is an isoquinoline alkaloid with micromolar affinity for dopamine D2 (antagonist, pKi = 6.08) and 5-HT1A (agonist, pKi = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors.
S3917	Tetrahydrocurcumin	Tetrahydrocurcumin (Tetrahydrodiferuloylmethane, Tetrahydro Curcumin), a major metabolite of curcumin, possesses strong antioxidant and cardioprotective properties. Tetrahydrocurcumin is a Curcuminoid found in turmeric (Curcuma longa) that is produced by the reduction of Curcumin. Tetrahydrocurcumin inhibit CYP2C9 and CYP3A4.
S5559	Tetrahydropalmatine	Tetrahydropalmatine, a plant alkaloid used as an ingredient in dietary supplement products, is a potent and selective D1 receptor antagonist.
S3854	Tetrahydropalmatine hydrochloride	Tetrahydropalmatine (THP, Gindarine, 1-Tetrahydropalmitine) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo), but also in other plants such as Stephania rotunda. It is a potent muscle relaxant. Tetrahydropalmatine hydrochloride acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats.
S5154	Tetrahydropiperine	Tetrahydropiperine (Cosmoperine), derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.
S4043	Tetrahydrozoline HCl	Tetrahydrozoline (Tetryzoline) HCl is an imidazoline derivative with alpha receptor agonist activity.
E2644	Tetramethylcurcumin	Tetramethylcurcumin (FLLL31), a small-molecule signal transducer and activator of transcription 3 (STAT3) inhibitor derived from curcumin, binds selectively to Janus kinase 2 and the STAT3 Src homology-2 domain, which serve crucial roles in STAT3 dimerization and signal transduction.
S3956	Tetramethylpyrazine	Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S2274	Tetramethylsilane	Tetramethylsilane can be used as a silicon precursor for the synthesis of silicon-doped diamond-like carbon base (DLC-Si) films and silicon carbide (SiC) block crystals. It can also be used as hydrocarbon substrates for the study of intermolecular C-H bond activation.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S2432	Tetramethylthiuram monosulfide	Tetramethylthiuram monosulfide is used on a large scale as a catalyst in rubber-processing techniques. Tetramethylthiuram monosulfide possesses a medium-degree toxicity and causes point mutations in strains TA 100 and TA 1535 (Salmonella typhimurium LT 2).This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S4094	Tetramisole HCl	Tetramisole(R-829,(±)-Tetramisole hydrochloride) is a mixture of dextro- and levo isomers used as an anthelmintic.
S2403	Tetrandrine	Tetrandrine, a bis-benzylisoquinoline alkaloid derived from Stephania tetrandra, is a calcium channel blocker.
E1166	tetrathiomolybdate	Tetrathiomolybdate (TM) is used in the clinic for the treatment of Wilson’s disease by inducing dimerization of the metal-binding domain of the cellular copper efflux protein ATP7B (WLN4) through a unique sulfur-bridged Mo2S6O2 cluster.
E2906	Tetrazolium Red	Tetrazolium Red(2,3,5-Triphenyltetrazolium chloride, TPTZ, TTC) is a dye and has been successfully used for early histochemical diagnosis of myocardial infractions.
S5727	Tetryzoline	Tetryzoline (Tetrahydrozoline) is an alpha-adrenergic agonist used in some over-the-counter eye drops and nasal sprays.
S7059	Tezacaftor (VX-661)	Tezacaftor (VX-661) is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
A2307	Tezepelumab (Anti-TSLP)	Tezepelumab (Anti-TSLP) is a potent human IgG2 monoclonal antibody that inhibits the binding of TSLP to the TSLP receptor, and also has potent efficacy and mechanism in asthma.
S6780	TFAP	TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective and cell-permeable cyclooxygenase-1 (COX-1) inhibitor with IC50 of 0.8 μM.
S0391	TG-89	TG-89 is an inhibitor of JAK2 with IC50 of 11.2 μM.
S1352	TG100-115	TG100-115 is a PI3Kγ/δ inhibitor with IC50 of 83 nM/235 nM, with little effect on PI3Kα/β. Phase 1/2.
S2692	TG101209	TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET (c-RET) with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.
S6793	TG4-155	TG4-155 is a potent and selective Prostaglandin Receptor EP2(PTGER2) antagonist with K_i value of 9.9 nM.
L5600	TGF-beta/Smad compound library	A unique collection of 156 small molecules with biological activity used for TGF-beta/Smad pathway research.
E2394	TGFβRI-IN-3	TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology, inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4.
S0158	TGN020	TGN-020 (compound 9) is a selective aquaporin 4 (AQP4) inhibitor with IC50 of 3.1 μM that may have an inhibitory effect on diabetic retinal edema.
S0193	TGR5 Receptor Agonist	TGR5 Receptor Agonist (TGR5, CCDC, MDK00245, compd 6) is a potent agonist of TGR5(GPCR19, GPBAR1, M-BAR). TGR5 Receptor Agonist shows improved potency with pEC50 of 6.8 and 7.5 in the U2-OS cell assay and in melanophore cells, respectively.
S1169	TGX-221	TGX-221 is a p110β-specific inhibitor with IC50 of 5 nM in a cell-free assay, 1000-fold more selective for p110β than p110α.
S6836	TH-257	TH-257 is a potent and exquisitely selective LIM kinase (LIMK) inhibitor with IC50 of 84 nM and 39 nM for LIMK1 and LIMK2, respectively.
E1277	TH10785	TH10785 controls the catalytic activity mediated by a nitrogen base within molecular structure of cells and increases 8-oxoguanine DNA glycosylase 1 (OGG1) recruitment and repair of oxidative DNA damage.
E1274	TH1760	TH1760 (Compound 18) is a first-in-class, potent, selective and cell-active NUDT15 (MTH2) inhibitor with an IC50 value of 25 nM.
E0103	TH263	TH-263, a diaryl sulfonamide derivative, is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257.
S7631	TH287	TH287 is a potent and selective MTH1 (NUDT1) inhibitor with IC50 of 0.8 nM.
E2849	TH5427	TH5427 is a potent and cell-active NUDT5 (also called NUDIX5) inhibitor that can be used to further understand the role of NUDT5 in biological systems.
S8913	TH5487	TH5487 is a selective active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1) with IC50 of 342 nM.
S7632	TH588	TH588 is a potent and selective MTH1 (NUDT1) inhibitor with IC50 of 5 nM. It has no relevant inhibition of any of the other tested proteins at 100 μM, although TH588 showed reasonable selectivity when tested on a much larger panel of 87 enzymes, GPCRs, kinases, ion channels and transporters at 10 μM.
S8979	THAL-SNS-032	THAL-SNS-032 is a selective Cyclin-dependent kinase 9 (CDK9) degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN).
S1193	Thalidomide	Thalidomide was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1.
E2390	Thalidomide-5-NH2-CH2-COOH	Thalidomide-5-NH2-CH2-COOH is a potent and selective inhibitor of tropomyosin receptor kinase (Trk).
S6397	Thalidomide-NH-C4-NH-Boc	Thalidomide-NH-C4-NH-Boc is a novel, potent, and selective class of Bromodomain-containing protein 4 (BRD4) and Bromodomain-containing protein 2 (BRD2) degrader for the development of therapeutics to treat cancers.
S6794	Thalidomide-O-COOH (Cereblon ligand 3)	Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3), a Thalidomide-based Cereblon (CRBN) ligand, is used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs (Proteolysis Targeting Chimera).
S1015	Thalidomide-OH	Thalidomide-OH (Cereblon ligand 2, E3 ligase Ligand 2) is a presumed hydroxylated thalidomide metabolite, with weak antiangiogenic activity (the average inhibition rate of vessel density was 14% in 100 μg), also can be applicable to the recruitment of CRBN protein.
S7895	Thapsigargin	Thapsigargin is a potent, non-competitive inhibitor of the sarco/endoplasmic reticulum Ca²⁺ ATPase (SERCA) with IC50 of 0.353 nM or 0.448 nM for the carbachol-evoked [Ca2+]i-transients with or without a KCl-prestimulation. Thapsigargin induces cell apoptosis. Thapsigargin is extracted from a plant, Thapsia garganica.
E0066	Theaflavin 3,3'-digallate	Theaflavin 3,3'-digallate (TF-3, ZP10, TFDG) is a black tea polyphenol and acts as a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM.
S8584	Theliatinib (HMPL-309)	Theliatinib (HMPL-309) is a highly potent EGFR inhibitor with Ki value of 0.05 nM against the wild type EGFR and IC50 values of 3 nM and 22 nM against EGFR and EGFR T790M/L858R mutant. It demonstrats 50 fold greater selectivity for EGFR compared to 72 other kinases.
S2368	Theobromine	Theobromine (3,7-Dimethylxanthine) is a xanthine alkaloid widely consumed as stimulants and snacks in coffee and cocoa based foods and most often as part of ingredients in drugs.
S3988	Theophylline-7-acetic acid	Theophylline-7-acetic acid (Acefylline, acetyloxytheophylline, Carboxymethyltheophylline), acting as an adenosine receptor antagonist, is a stimulant drug of the xanthine chemical class.
S1739	Thiabendazole	Thiabendazole inhibits the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property, used as an anthelmintic and fungicide agent. It is a potent inhibitor of cytochrome P450 1A2 (CYP1A2).
S7213	Thiamet G	Thiamet G is a potent, selective O-GlcNAcase inhibitor with K_iof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase.
S3211	Thiamine HCl (Vitamin B1)	Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.
S4486	Thiamine monochloride	Thiamine (Vitamin B1) monochloride is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.
S2991	Thiamine monophosphate chloride dihydrate	Thiamine monophosphate chloride dihydrate (Vitamin B1 Monophosphate Chloride, Sineurina, Phosphothiamine) is an endogenous metabolite.
S5955	Thiamine nitrate	Thiamine (Vitamin B1) nitrate is an essential vitamin that plays an important role in cellular production of energy from ingested food and enhances normal neuronal actives.
S6102	Thiamine pyrophosphate hydrochloride	Thiamine pyrophosphate hydrochloride (cocarboxylase) is a thiamine (vitamin B1) derivative which is produced by the enzyme thiamine diphosphokinase. It is a coenzyme of many enzymes, most of which occur in prokaryotes and is involved in the regulation of basic metabolism.
S2583	Thiamphenicol	Thiamphenicol (Thiophenicol,Dextrosulphenidol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.
S6821	Thiazolyl Blue	Thiazolyl Blue (MTT, Tetrazolium bromide, Methylthiazolyldiphenyl-tetrazolium bromide, Methylthialazole Tetrazolium) is a cell-permeable and positively charged colorimetric agent that is widely used to detect reductive metabolism in cells and to measure cell proliferation, cytotoxicity, and apoptosis. Thiazolyl Blue (MTT) is reduced from yellow color to purple formazan in living cells.
S1459	Thiazovivin	Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation.
S3646	Thimerosal	Thimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
E0156	Thioacetamide	Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration.
E4407	Thiobarbituric acid	Thiobarbituric acid (2-Thiobarbituric acid) is a colorimetric reagent commonly used in the detection of malondialdehyde (MDA), a marker of lipid peroxidation.
S5049	Thiocolchicoside	Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) is a natural occuring glycoside originated from the flower seeds of superba gloriosa with anti-inflammatory and analgesic properties as well as pronounced convulsant activity. It is also an antagonist of GABAA receptor.
S3996	Thioctic acid	Thioctic acid (DL-α-Lipoic acid) is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form.
S6873	Thioflavin T	Thioflavin T (ThT, Thioflavine T, Basic Yellow 1) is a benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils and is commonly used to diagnose amyloid fibrils. Thioflavin T is found to exist as micelles at concentrations commonly used to monitor fibrils by fluorescence assay. The micelles of Thioflavin T bind to amyloid fibrils leading to enhancement of fluorescence emission.
S6825	Thioflavine S	Thioflavine S (Thioflavin S, Direct Yellow 7) is a fluorogenic compound which becomes fluorescent only after oxidation. Thioflavine S is used as a fluorescent histochemical marker of dense core senile plaques.Thioflavine S can bind to dense-core amyloid-β deposits.
S1774	Thioguanine	Thioguanine, a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.
S3686	Thioisonicotinamide	Thioisonicotinamide (Pyridine-4-carbothioamide, Isothionicotinamide, 4-Pyridylthiocarboxamide) is a synthetic intermediate used for pharmaceutical synthesis.
S6313	Thiolactic Acid	Thiolactic acid is a carboxylic acid like lactic acid and is predominantly used in cosmetic applications and hair permanent waving formulations.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S8245	Thiomyristoyl	Thiomyristoyl (TM) is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM. It inhibits SIRT1 with an IC50 value of 98 μM and does not inhibit SIRT3 even at 200 μM.
S5563	Thioridazine hydrochloride	Thioridazine (Aldazine, Mellaril) is a potent antianxiety and antipsychotic agent.
S4354	Thiostrepton	Thiostrepton (Alaninamide, Bryamycin, Thiactin) is a natural cyclic oligopeptide antibiotic, derived from several strains of strepromycetes.
S1775	Thiotepa	Thiotepa (Thioplex, Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide) is an alkylating agent used to treat cancer.
S6469	Thonzylamine	Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug.
S4803	Thymidine	Thymidine is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix.
S3221	Thymidine 5'-monophosphate disodium salt	Thymidine-5'-monophosphate (5'-Thymidylic acid) disodium salt is an active endogenous metabolite.
S9382	Thymine	Thymine (5-methyluracil) is one of the four nucleobases in the nucleic acid of DNA.
S5157	Thymol	Thymol (2-isopropyl-5-methylphenol, IPMP), a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro.
S3668	Thymopentin	Thymopentin (TP5) has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells.
S4761	Thymoquinone	Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa with anti-inflammatory and anti-oxidant effects.
P1137	Thymulin	Thymulin (FTS) is a neuroendocrine hormone with immunoregulatory actions, with anti-inflammatory potential by downregulating the release of inflammatory mediators, such as cytokines and chemokines, upregulating anti-inflammatory factors, such as interleukin (IL)-10, exerting molecular control via the regulation of transcription factors and mediators.
E3043	Thymus Serpillum Extract	Thymus Serpillum Extract is extracted from Thymus serpyllum, is an aromatic medicinal plant with several several biological properties, including anticancer activity.
S7549	THZ1 2HCl	THZ1 is a covalent CDK7 inhibitor which has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7.
S7969	THZ2	THZ2, a THZ1 analog, is a selective inhibitor of CDK7 with IC50 of 13.9 nM. THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10 nM.
S6595	THZ531	THZ531 is a selective covalent inhibitor of CDK12 and CDK13 with IC50 values of 158 and 69 nM, respectively.
E1924	TI17
S4675	Tiagabine	Tiagabine (Gabitril, NO050328, NO328, TGB) is an anti-convulsive medication and a selective gamma-aminobutyric acid (GABA) reuptake inhibitor.
S4661	Tiagabine hydrochloride	Tiagabine Hydrochloride (Gabitril, NO050328, NO328, TGB) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor.
S5040	Tiamulin	Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis. Tiamulin has sustained antibacterial activity against specified bacterial species and rapidly growing and fastidious animal pathogens.
S4988	Tiamulin fumarate	Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis.
S9509	Tiapride Hydrochloride	Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain and is used to treat a variety of neurological and psychiatric disorders.
S5661	Tiaprofenic acid	Tiaprofenic acid (Tiaprofensaeure, Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
S7963	TIC10 (ONC201)	TIC10 (ONC201) inactivates Akt and ERK to induce TNF-related apoptosis-inducing ligand (TRAIL) through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
S7127	TIC10 Analogue	TIC10 Analogue is an analogue of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
S4079	Ticagrelor	Ticagrelor (AZD6140, AR-C 126532XX) is the first reversibly binding oral P2Y12 receptor antagonist with K_i of 2 nM.
S3193	Ticarcillin sodium	Ticarcillin (AB 2288, BRL 2288) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
S0721	Ticlopidine	Ticlopidine (Yuclid, Ticlopidinum, Ticlopidina,PCR 5332) is an orally active inhibitor of platelet aggregation induced by adenosine diphosphate (ADP). Ticlopidine is also an inhibitor of CYP2B6 with Ki of 0.2 μM.
S1984	Ticlopidine HCl	Ticlopidine HCl is an P2 receptor inhibitor against ADP-induced platelet aggregation with IC50 of ~2 μM.
S2823	Tideglusib	Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM in a cell-free assay; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.
A3170	Tidutamab (Anti-CD3 & SSTR2)	Tidutamab (Anti-CD3 & SSTR2) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and T-cell binding domain (CD3). It can be used in neuroendocrine tumors (NETs) and small cell lung cancer (SCLC). MW :147.36 KD.
S1577	Tie2 kinase inhibitor 1	Tie2 kinase inhibitor 1 is an optimized compound of SB-203580, selective to Tie2 with IC50 of 0.25 μM, 200-fold more potent than p38.
S1403	Tigecycline	Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway.
S3789	Tiglic acid	Tiglic acid (Cevadic acid, Sabadillic acid, Tiglinic acid) is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. It is used in making perfumes and flavoring agents.
S5334	Tigogenin	Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis.
S6423	Tildipirosin	Tildipirosin is a 16-membered ring, tribasic and semi-synthetic macrolide antibiotic.
S5287	Tiletamine Hydrochloride	Tiletamine is a lipophilc and potent vetrinary anesthetic. It is also a NMDA receptor antagonist.
S4122	Tilmicosin	Tilmicosin (EL 870,LY-177370) is a macrolide antibiotic.
S5573	Tilmicosin phosphate	Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease.
S5020	Tilorone dihydrochloride	Tilorone dihydrochloride is a broad-spectrum, orally active antiviral agent that activates interferon production. It has antitumor, anti-inflammatory properties.
A2596	Tilvestamab (Anti-AXL / UFO)	Tilvestamab (Anti-AXL / UFO) is a humanized antibody targeting AXL.Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas. MW :146.16 KD.
E0809	Timapiprant Sodium	Timapiprant sodium (OC000459 sodium), a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist, potently displaces [³H]PGD2 from human recombinant DP2, rat recombinant DP2, and human native DP2 with Ki values of 13, 3 and 4 nM, respectively.
S4123	Timolol Maleate	Timolol Maleate (MK-950,(S)-Timolol Maleate) is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with K_i of 1.97 nM/2.0 nM.
S4993	Timonacic	Timonacic (Thiazolidine-4-carboxylic acid, Detoxepa, Hepalidine, 1,3-Thiazolidine-4-carboxylic acid) is a cyclic sulfur amino acid derivative with potential antineoplastic and antioxidant activities.
S9108	Timosaponin A3	Timosaponin A3 (Filiferin B, AneMarsaponin A3), one of the major steroidal saponin components isolated from Anemarrhena asphodeloides, displays promising pharmacological activity in improving learning, memory, and antineoplastic activity.
S9273	Timosaponin BII	Timosaponin BII (BII, Prototimosaponin AIII) is a steroidal saponin showing potential anti-dementia and antioxidant activity.
E1435	Tinengotinib	Tinengotinib (TT-00420) is a novel multiple kinase inhibitor that strongly inhibits Aurora A/B with IC50 values of 1.2/3.3 nM respectively. It also exhibits potent inhibitory activity on FGFR1/2/3, VEGFR1, JAK1/2, and CSF1R and can be used to treat several prominent signaling pathways in triple-negative breast cancer(TNBC).
S4068	Tinidazole	Tinidazole (CP12574) is an anti-parasitic drug.
S6472	Tinoridine hydrochloride	Tinoridine hydrochloride (Y-3642) is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity.
S8769	Tinostamustine(EDO-S101)	Tinostamustine(EDO-S101) is a first-in-class alkylating deacetylase inhibitor with IC50 values of 9 nM, 9 nM, 25 nM and 107 nM for HDAC1, HDAC2, HDAC3 and HDAC8 (Class 1 HDACs) respectively and 6 nM, 72 nM for HDAC6 and HDAC10 (Class II HDACs).
S1910	Tioconazole	Tioconazole (UK-20349) is an antifungal medication with an average IC50 of 1.7 μM.
S2062	Tiopronin	Tiopronin is an antioxidant agent, used for the treatment of cystinuria by controlling the rate of cystine precipitation and excretion.
S2547	Tiotropium Bromide hydrate	Tiotropium Bromide hydrate (BA 679BR) is a monohydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.
S2603	Tioxolone	Tioxolone(Thioxolone) is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.
S1453	Tipifarnib	Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.
S3731	Tipiracil hydrochloride	Tipiracil (MA-1) is an inhibitor of thymidine phosphorylase, the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine.
S7922	Tiplaxtinin (PAI-039)	Tiplaxtinin(PAI-039) is an orally efficacious and selective plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 2.7 μM.
S8166	tirabrutinib(ONO-4059) hydrochloride	Tirabrutinib Hydrochloride (ONO-4059, GS-4059) is a highly potent and selective BTK inhibitor with an IC50 of 2.2 nM.
A2028	Tiragolumab (anti-TIGIT)	Tiragolumab (anti-TIGIT) (RG6058, MTIG7192A) is a humanized IgG1/kappa monoclonal antibody that binds TIGIT to prevent its interaction with its ligand PVR (CD155).
S2426	Tirapazamine	Tirapazamine (NSC 130181, SR 259075, SR 4233, Tirazone, WIN 59075) is a new anticancer drug in solid tumours. Tirapazamine exhibits preferential tumour cell killing and high specific toxicity to cells at low oxygen tensions.
S0196	Tirasemtiv (CK-2017357)	Tirasemtiv (CK-2017357, CK-357) is a direct fast skeletal muscle troponin activator that sensitizes the sarcomere to calcium.
S4185	Tiratricol	Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue.
S2700	Tirbanibulin	Tirbanibulin, the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Phase 2.
S3085	Tirofiban	Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
S8594	Tirofiban Hydrochloride	Tirofiban Hydrochloride (MK-383) is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation. It is more soluable than Tirofiban.
P1206	Tirzepatide (LY3298176) sodium	Tirzepatide (LY3298176, GIP/GLP-1 RA, TZP) sodium is a dual GIP/GLP-1 receptor agonist. Tirzepatide differentially induces internalization of the GIP and GLP-1 receptors with EC50 values of 18.2 nM and 18.1 nM, respectively.
D4051	Tisotumab vedotin	Tisotumab vedotin (TF-011-MMAE, HuMax-TF-ADC) is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Tisotumab vedotin has the potential for use in research of solid tumors mainly in cervical cancer.
S4872	Titanium tetrafluoride	Titanium tetrafluoride is an inorganic compound that is an effective but instable caries preventive agent.
S2753	Tivantinib	Tivantinib is the first non-ATP-competitive c-Met inhibitor with K_i of 0.355 μM in a cell-free assay, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. Tivantinib (ARQ 197) induces a G2/M arrest and apoptosis.
S1207	Tivozanib	Tivozanib is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.
S5537	Tizanidine	Tizanidine is an imidazoline derivative and a centrally acting α2 adrenergic agonist used as a muscle relaxant for therapy of acute muscle spasms and chronic spasticity.
S1437	Tizanidine HCl	Tizanidine HCl (DS 103-282) is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.
S5394	Tizoxanide	Tizoxanide (Desacetyl-nitazoxanide), a thiazolide anti-infective, is active against anaerobic bacteria, protozoa, and a range of viruses in cell culture models, and is currently in phase II clinical development for treating chronic hepatitis C.
E1721	TJ-M2010-5	TJ-M2010-5 is a small molecule inhibitor of MyD88 that selectively binds to the Toll/Interleukin-1 receptor (TIR) domain of MyD88, disrupting its homodimerization and subsequently inhibiting the Toll-like receptor (TLR)/MyD88 signaling pathway. TJ-M2010-5 exhibits an anti-hepatic fibrosis effect with the potential to treat liver fibrosis.
S6973	TJ191	TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.
S9718	TK216	TK216 is a potent inhibitor targeting E26 transformation specific (ETS) factors via blocking the protein-protein interaction with RNA helicases. TK216 exhibits antilymphoma activity.
E2643	TL02-59	TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM.
E1849	TL12-186
P1209	TLQP-21 TFA	LQP-21 TFA (TLQP-21 Trifluoroacetate) is a VGF-derived peptide that activates the C3aR1 receptor through a folding-upon-binding mechanism.
S6597	TLR2-IN-C29	TLR2-IN-C29 (C29) is a Toll-like receptor 2 (TLR2) inhibitor that inhibits TLR2/1 and TLR2/6 signaling.
S0822	TLR4-IN-C34	TLR4-IN-C34 (TLR4-C34, C34, TLR4-C34-IN) is a potent and selective antagonist of Toll-like receptor 4 (TLR4). TLR4-IN-C34 reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
E0639	TLR7/8 agonist 1 dihydrochloride	TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline.TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC50 of 20 nM.
S0533	TLX agonist 1	TLX agonist 1 (CCRP2, SUN23314) is a modulator of orphan nuclear receptor tailless (TLX, NR2E1) with EC50 of 1.0 μM and Kd of 650 nM. TLX agonist 1 (CCRP2, SUN23314) binds to recombinant TLX protein and enhances TLX transcriptional repressive activity.
S6776	TM5275 Sodium	TM 5275 sodium is an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 6.95 μM..
S6778	TM5441	TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 ranging between 9.7 μM and 60.3 μM. TM5441 induces intrinsic apoptosis in several human cancer cell lines.
S6822	TMB dihydrochloride	TMB dihydrochloride (3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate, TMB-d, BM blue, Sure Blue TMB) is an excellent colorimetric substrate for detection of horseradish peroxidase (HRP) labeled probes and is used in staining procedures in immunohistochemistry and in enzyme-linked immunosorbent assays (ELISA).
S5283	TMB-PS	TMB-PS (TMBZ-PS, TetraMethyl BisPhenol S, Bis-(2,6dimethyl-4-hydroxyphenyl)-sulfone) is a chromogenic reagent for the detection of hydrogen peroxide e.g. in the enzymatic analysis of body fluids.
S0836	TMN355	TMN355 (Compound 3i) is a potent inhibitor of cyclophilin A (CypA) with IC50 of 1.52 nM and reduces foam cell formation and cytokine secretion. TMN355 is used for the treatment of atherosclerosis.
S8502	TMP195	TMP195 (TFMO 2) is a selective, first-in-class, class IIa HDAC inhibitor with Ki of 59, 60, 26 and 15nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
S7324	TMP269	TMP269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
S3483	TMP778	TMP778 is a selective inhibitor of RORγt with an IC50 of 5 nM in the Fluorescence Resonance Energy Transfer (FRET) assay and an IC50 of 17 nM in the RORγ assay.
P1202	TMPyP4 tosylate	TMPyP4 tosylate (TMP 1363), a quadruplex-specific ligand, inhibits the interaction between G-quadruplex (G4) and IGF-1 (Insulin-like growth factor type I). TMPyP4 tosylate is also a telomerase inhibitor with antitumor effects.
E2978	TMRE	TMRE (Tetramethylrhodamine ethyl ester perchlorate, TMRE perchlorate) is a non-cytotoxic cell-permeant fluorogenic dye most commonly used to assess mitochondrial function using live cell fluorescence microscopy and flow cytometry.
E2945	TMRM Perchlorate	TMRM Perchlorate (T668) is a membrane-permeant, cationic, fluorescent dye that can label mitochondria and mark embryonic stem cell/induced pluripotent stem cell-derived cardiomyocytes. It is useful for the isolation of mature cardiomyocytes. It is also used as a sensitive probe for the detection of mitochondrial membrane potential.
E0531	TMS	TMS ((E)-2,3',4,5'-tetramethoxystilbene) is a selective and competitive human cytochrome P450s B1 (CYP1B1) inhibitor with an IC50 of 6 nM.
S1237	TMZ(Temozolomide)	TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.
S2514	Tobramycin	Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.
S5533	Tobramycin sulfate	Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.
S5272	Toceranib phosphate	Toceranib phosphate (Palladia, SU11654), the phosphate salt of toceranib, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR, and Kit with Ki values of 6 nM and 5 nM for Flk-1/KDR and PDGFRβ, respectively.
A2012	Tocilizumab (anti-IL-6R)	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD.
S5568	Tocofersolan	Tocofersolan (Tocophersolan) is a synthetic water-soluble version of vitamin E that is used in treatment of vitamin E deficiency.
S9194	Toddalolactone	Toddalolactone, a natural coumarin, inhibits the activity of recombinant human Plasminogen activator inhibitor-1 (PAI-1) in a dose-dependent manner, yielding an IC50 value of 37.31 ± 3.23 μM.
S6690	TOFA	TOFA is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA). Inside the cell, TOFA is converted to TOFyl-CoA (5-tetradecyloxy-2-furoyl-CoA), exerting an allosteric inhibition on ACCA. TOFA blocks fatty acid synthesis and induces cell death in a dose-dependent manner.
S2789	Tofacitinib	Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.
S5001	Tofacitinib (CP-690550) Citrate	Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.
S8558	Tofogliflozin(CSG 452)	Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.
S4124	Tolazoline HCl	Tolazoline(Imidaline hydrochloride,NSC35110 hydrochloride) is a non-selective competitive α-adrenergic receptor antagonist.
S2443	Tolbutamide (HLS 831)	Tolbutamide (HLS 831) is an inhibitor of potassium channel, used for type II diabetes.
S4021	Tolcapone	Tolcapone (Ro 40-7592) is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with K_i of 30 nM.
E0041	Tolebrutinib	Tolebrutinib is an oral, CNS-penetrant, irreversible inhibitor of Bruton's tyrosine kinase (BTK) with IC50s of 0.4 nM and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively.
S1959	Tolfenamic Acid	Tolfenamic Acid(Clotam) is a COX-2 inhibitor with IC50 of 0.2 μM.
S8321	Tolimidone (MLR-1023)	Tolimidone (MLR-1023) is a Lyn kinase activator and a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetes.
S8681	Tolinapant (ASTX660)	Tolinapant (ASTX660) is a potent, non-peptidomimetic antagonist of cIAP1/2 and XIAP that inhibits the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L, respectively.
S4832	Tolmetin	Tolmetin (Tolectin) is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
S4360	Tolmetin Sodium	Tolmetin(MCN2559) is a non-steroidal anti-inflammatory drug of the arylalkanoic acids. Tolmetin sodium dihydrate is a non-steroidal antiinflammatory agent, and acts as a non-selective COX inhibitor.
S2058	Tolnaftate	Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent.
S0160	Toloxatone (MD69276)	Toloxatone (MD69276, Humoryl, Perenum, Umoril) is a reversible inhibitor of monoamine oxidase A (MAO-A) with IC50 of  0.93 µM. Toloxatone is an antidepressant agent.
S4200	Tolperisone HCl	Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant.
S4044	Toltrazuril	Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
E2958	Toluidine Blue O	Toluidine Blue O (Toluidine Blue) is a thiazine dye of the quinone-imine family and is cationic in nature. Toluidine Blue O along with light-emitting diode has been used as a photosensitizer to control in vitro biofilms and to kill gram-negative bacteria. Toluidine Blue has wide applications in vital staining in living tissues and used as a special stain.
S2593	Tolvaptan	Tolvaptan (OPC-41061) is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.
S9430	Tomatidine Hydrochloride	Tomatidine Hydrochloride, a natural steroidal alkaloid, possesses potent antibacterial activity and has anti-inflammatory effects in macrophages.
S9444	Tomatine	Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S8275	Tomivosertib (eFT-508)	Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. Tomivosertib (eFT-508) inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.
E3101	Toosendan Fructus Extract	Toosendan Fructus Extract is extracted from Fructus Meliae Toosendan, which has potent anticoccidial effects and also acts as an alternative anticoccidial agent for avian coccidiosis control.
S1438	Topiramate	Topiramate (MCN 4853, RWJ 17021) is a mutil-targeted inhibitor, including voltage-gated sodium channel and calcium channel, AMPA/kainate receptor and carbonic anhydrase, used to treat epilepsy.
S3719	Topiroxostat	Topiroxostat is a xanthine oxidoreductase (XOR) inhibitor and used for treatment of gout and hyperuricemia. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment.
S9321	Topotecan	Topotecan(NSC609699,Nogitecan,SKFS 104864A) is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
S1231	Topotecan HCl	Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.
S2792	Torcetrapib	Torcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.
S1776	Toremifene Citrate (NK 622)	Toremifene Citrate (NK 622, NSC 613680) is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer.
S2827	Torin 1	Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits 1000-fold selectivity for mTOR than PI3K.
S2817	Torin 2	Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53−/− MEFs cell line; 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM,in PC3 cell lines respectively. Torin 2 decreases cell viability and induces autophagy and apoptosis.
S2218	Torkinib (PP242)	Torkinib (PP242) is a selective mTOR inhibitor with IC50 of 8 nM in cell-free assays; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively. Torkinib (PP242) induces mitophagy and apoptosis.
E3194	Torreyae Semen Extract	Torreyae Semen Extract is extracted from the seed of Torreya grandis, which is used in treating intestinal parasites.
S1698	Torsemide	Torsemide (AC-4464, JDL-464) is a pyridyl sulfonylurea with a chemical structure between that of traditional loop diuretics and Cl- channel blockers, used to treat hypertension.
S5605	Tos-Arg-OMe HCl	Tos-Arg-OMe HCl, a kind of amino acid derivatives, is a substrate for trypsin, plasmin, thrombin and orther proteases.
S1522	Tosedostat (CHR2797)	Tosedostat (CHR2797) is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2. Phase 2.
S5299	Tosufloxacin p-Toluenesulfonate Hydrate	Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that is used to treat susceptible infections.
S7121	Tovorafenib (MLN2480)	Tovorafenib (MLN2480, BIIB-024, TAK580, AMG-2112819, BSK1369, DAY-101) is an oral, selective pan-Raf kinase inhibitor in chinical trials.
E2504	Toyocamycin	Toyocamycin(Vengicide), an adenosine analog, acts as an inhibitor of XBP1. Toyocamycin is also a specific inhibitor of CDK9 with an IC50 value of 79 nM.
S1048	Tozasertib (VX-680)	Tozasertib (VX-680) is a pan-Aurora inhibitor, mostly against Aurora A with K_i_app of 0.6 nM in a cell-free assay, less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases. The only exceptions are Fms-related tyrosine kinase-3 (FLT-3) and BCR-ABL tyrosine kinase, which are inhibited by the Tozasertib with both Ki of 30 nM. Tozasertib induces apoptosis and autophagy. Phase 2.
E1088	TP-064	TP-064 is a potent and selective small molecule inhibitor of PRMT4 with IC50 < 10 nM, >100 fold more selective for PRMT4 than other PRMTs.
E1328	TP-1454	TP-1454 is an activator of PKM2 with AC50 of 10 Nm in biochemical assays.TP-1454 modulates tumor-immune responses by destabilizing T-regulatory cells.
S6774	TP-3654	TP-3654 is the second-generation PIM inhibitor with K_i values of 5 nM, 239 nM, and 42 nM for PIM-1, PIM-2 and PIM-3, respectively.
S8700	TP0427736 HCl	TP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM.
S0729	TP0463518	TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5.3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively.
S2824	TPCA-1	TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1. TPCA-1 is also an inhibitor of STAT3 and enhances apoptosis.
S6962	TPEN	TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosis in NB4 cells via negatively regulating intracellular NO and Zn²⁺ signaling. TPEN (TPEDA) may be a potential therapeutic strategy for APL (acute promyelocytic leukemia).TPEN induces DNA damage and increases intracellular ROS production and also inhibits cell proliferation.
E1432	TPH104m	TPH104m is a thienopyrimidine-hydrazinyl analog that inhibits Drp1 phosphorylation and induces non-apoptotic TNBC cell death. It also significantly inhibits TNBC proliferation.
S6570	TPI-1	TPI-1 (Tyrosine Phosphatase Inhibitor 1) is a potent inhibitor of SHP-1 with IC50 of 40 nM for recombinant SHP-1. TPI-1 exhibits anticancer activity.
E2847	TPPU	TPPU is a soluble epoxide hydrolase (sEH) inhibitor with IC50 values of 37 and 3.7 nM for monkey and human sEH, respectively.
S9826	TPX-0046	TPX-0046 is a novel RET/SRC inhibitor with a mean IC50 of 17 nM for RET^G810R in Ba/F3 cell proliferation assay.
S6698	TQB3804	TQB3804 is a selective and potent EGFR kinase inhibitor with IC50 of 0.46 nM, 0.13 nM, 0.26 nM, 0.19 nM and 1.07 nM for for EGFR^{d746-750/T790M/C797S}, EGFR^{L858R/T790M/C797S}, EGFR^{d746-750/T790M}, EGFR^L858R/T790M and EGFR^WT, respectively. TQB3804 (EGFR-IN-7) shows anti-tumor activity.
S0314	TR-14035	TR-14035 (SB 683698, MDK-1191) is a a dual alpha4beta (α4β) integrin antagonist with IC50 of 7 nM and 87 nM for alpha4beta7 (α4β7) and alpha4beta1 (α4β1), respectively.
S7758	Trabectedin	Trabectedin (Ecteinascidin 743, ET-743) is a marine alkaloid isolated from the Caribbean tunicate Ecteinascidia turbinata with antitumour activity. Trabectedin binds to the N2 of guanine in the minor groove, causing DNA damage and affecting transcription regulation in a promoter- and gene-specific manner.
S3284	Tracheloside	Tracheloside is a lignan glycoside isolated from seeds of Carthamus tinctorius with anti-estrogenic effects. Tracheloside significantly decreases the activity of alkaline phosphatase (AP) (an estrogen-inducible marker enzyme) with IC50 of 0.31 μg/ml. Tracheloside promotes keratinocyte proliferation through ERK1/2 stimulation.
L8300	Traditional Chinese Medicine Library	A unique collection of 1907 traditional chinese medicine(TCM) monomer compounds used for high throughput screening(HTS) and high content screening(HCS).
S1160	TRAM-34	TRAM-34 (Triarylmethane-34) is a selective and potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1) with K_d of 20 nM, 200- to 1500-fold selective over other ion channels, and does not block cytochrome P450.
S2673	Trametinib (GSK1120212)	Trametinib (GSK1120212, JTP-74057) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. Trametinib activates autophagy and induces apoptosis.
S4484	Trametinib DMSO solvate	Trametinib DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activates autophagy and induces apoptosis.
S6468	Trandolapril	Trandolapril(RU44570) is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.
S1875	Tranexamic Acid	Tranexamic Acid(Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.
S1439	Tranilast	Tranilast is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
S6303	trans-2-Hexenal	Trans-2-hexenal (Leaf aldehyde) is an α,β-unsaturated carbonyl compound protecting plants against harmful substances.
S6327	trans-2-Methyl-2-pentenoic Acid	trans-2-Methyl-2-pentenoic Acid ((E)-2-Methyl-2-pentenoic Acid, strawberry acid) has a sweet berry-like aroma and flavor and is widely used in food flavor.
S6105	trans-3-Indoleacrylic acid	trans-3-Indoleacrylic acid is a metabolite of tryptophan.
S6069	trans-4-Hydroxycyclohexanecarboxylic Acid	trans-4-Hydroxycyclohexanecarboxylic acid is used as an organic intermediate.
S9478	Trans-4-Phenyl-3-buten-2-one	Trans-4-Phenyl-3-buten-2-one (trans-Benzylideneacetone, trans-Benzalacetone, trans-Benzylideneacetone) is an inhibitor of the enzyme phospholipase A2 (PLA2). Trans-4-Phenyl-3-buten-2-one is used as a flavouring agent, a fragrance and a bacterial metabolite.
S3090	trans-Aconitic acid	trans-Aconitic acid (TAA) is an abundant constituent in the leaves of Echinodorus grandiflorus, a medicinal plant used to treat rheumatoid arthritis in Brazil.
S3990	Trans-Anethole	Trans-anethole (4-Propenylanisole) is a phenylpropene derivative found in many essential oils, including anise oil. It has neuromodulatory, anxiolytic, antioxidative, antifungal, anti-inflammatory, and immunomodulatory activities.
E2641	trans-Chalcone	Trans-Chalcone, the backbone of flavonoids, also is a potent fatty acid synthase (FAS) with IC50 of 17.1 μg/mL, and α-amylase inhibitor, causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7, exerting antifungal and anticancer activities.
E0653	Trans-ferulic acid	Trans-ferulic acid is a potent activator of AMPKunder high glucose condition.
S5871	Trans-Tranilast	Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
S6168	trans-trans-Muconic acid	trans-trans-Muconic acid is a metabolite of benzene in humans.
S4884	Trans-Zeatin	Trans-Zeatina ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing. Trans-Zeatin inhibits UVB-induced MMP-1 expression, c-Jun activation and phosphorylation of ERK, JNK and p38 MAP kinases (MAPKs) dose-dependently.
S5678	trans-Zeatin-riboside	Zeatin Riboside is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process, and activate gene expression and metabolic activity. Zeatin riboside has an immunomodulatory effect by agonizing the mammalian adenosine A2A receptor.
S6171	trans-β-Hydromuconic acid	trans-β-Hydromuconic acid (trans-2-Butene-1,4-dicarboxylic Acid, 3-hexenediodicacid, β-Hydromuconic acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorders.
S4246	Tranylcypromine HCl	Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with K_i of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
S9464	Tranylcypromine Sulfate	Tranylcypromine Sulfate is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.
S4736	Trapidil	Trapidil (Rocornal, Trapymin, Avantrin, Trapymine) is a PDGF antagonist that can inhibit the proliferation of the PDGF-producing glioma cells.
A2007	Trastuzumab (anti-HER2)	Trastuzumab (anti-human HER2) is a humanized, recombinant monoclonal antibody that binds to the extracellular domain of HER2, MW:145.53 KD.
D4001	Trastuzumab deruxtecan (DS-8201a, T-DXd)	Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa. This product is supplied as 10mg/ml PBS solution.
D4003	Trastuzumab Emtansine（T-DM1）	Trastuzumab Emtansine(T-DM1,Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1.Trastuzumab emtansine has a molecular weight of 145kDa.This product is supplied as 10mg/ml PBS solution.
D4052	Trastuzumab MMAE	Trastuzumab MMAE is an antibody-drug conjugate (ADC) composed of an anti-HER2 antibody, conjugated to Monomethyl Auristatin E (MMAE), via a Mc linker. Trastuzumab MMAE has the potential for use in research of solid tumors mainly in HER2-positive breast cancer.
E0200	Trastuzumab-deruxtecan (DS-8201a, T-DXd)	Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa. This product is supplied as 10mg/ml PBS solution.This product is discontinued. We recommend the replacement products: D4001.
E2851	Trastuzumab-Emtansine（T-DM1）	Trastuzumab Emtansine(T-DM1,Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1.Trastuzumab emtansine has a molecular weight of 145kDa.This product is supplied as 10mg/ml PBS solution. This product is discontinued. We recommend the replacement products: D4003
S6163	Traumatic acid	Traumatic acid (Trans-2-dodecenedioic acid) is a plant hormone that was first isolated from damaged green beans. It is a potent wound healing agent and an intermediate in prostaglandin synthesis.
S3738	Travoprost	Travoprost (Travoprostum) is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor.
S5857	Trazodone	Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.
S2582	Trazodone HCl	Trazodone HCl (AF-1161, KB-831) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
S8305	TRC051384	TRC051384 is an inducer of heat shock protein 70 (HSP70) and potent anti-inflammatory agent.
E1503	TRC102 (methoxyamine hydrochloride)	TRC102 (methoxyamine hydrochloride, O-Methylhydroxylamine hydrochloride) is a reagent used for the preparation of O-methyl oximes or the synthesis of O-methyl oximes from aldehydes.
S7513	Trelagliptin	Trelagliptin (SYR-472), a potent, orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM, improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM).
S5063	Trelagliptin succinate	Trelagliptin succinate (SYR472) is a dipeptidyl peptidase IV (DPP-4) inhibitor which is used as a new long-acting drug for once-weekly treatment of type 2 diabetes mellitus (DM).
A2021	Tremelimumab (anti-CTLA-4)	Tremelimumab (Ticilimumab, CP-675,206) is a fully human monoclonal antibody that binds to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) on the surface of activated T lymphocytes.
E3826	Tremella Extract	Tremella Extract is extracted from Tremella, which has anti-fatigue and anti-anoxia effects.
S6958	Treosulfan	Treosulfan (NSC 39069, Treosulphan) is an alkylating agent used for conventional and high-dose chemotherapy regimens. Treosulfan is potently cytotoxic against pancreatic cancer cell lines.
S0325	Treprostinil sodium	Treprostinil sodium is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.
S7829	Tretazicar (CB1954)	Tretazicar (CB1954) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.
S0267	TRi-1	TRi-1 (HUN20688, TXNRD1 inhibitor 1) is a potent, specific and irreversible cytosolic thioredoxin reductase 1 (TXNRD1) inhibitor with IC50 of 12 nM. TRi-1 exhibits anti-cancer activity while having little mitochondrial toxicity.
S4581	Triacetin	Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) is a triglyceride that is used as an antifungal agent.
S4859	TriacetonaMine	TriacetonaMine (Tempidon, Tmpone, Odoratine, Vincubine), a member of the class of compounds known as piperidinones, is an extremely weak acidic compound found in green vegetables and tea.
S1933	Triamcinolone	Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated.
S1628	Triamcinolone Acetonide	Triamcinolone acetonide is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation.
S4080	Triamterene	Triamterene (SKF8542) blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM.
S7470	Triapine (3-AP)	Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2.
S6854	Triazavirin (TZV)	Triazavirin (TZV) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza.
S5483	Tribenzagan Hydrochloride	Tribenzagan Hydrochloride (Trimethobenzamide) is an orally available, antiemetic agent used in the therapy of nausea and vomiting associated with medications and gastrointestinal, viral and other illnesses.
E3111	Tribulus Terrestris Extract	Tribulus Terrestris Extract is extracted from Tribulus Terrestris, which has anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicidal, and anticariogenic activities.
S6286	Tricarballylic acid	Tricarballylic acid (β-Carboxyglutaric acid, Propane-1,2,3-tricarboxylic acid) is an inhibitor of aconitase and therefore interferes with the Krebs cycle.
S1667	Trichlormethiazide	Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide.
S3632	Trichloroisocyanuric acid	Trichloroisocyanuric acid (TCCA) is a safe and efficient reagent, useful for chlorination and oxidation reactions.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
E3233	Trichosanthis Fructus Extract	Trichosanthis Fructus Extract is extracted from Trichosanthis Fructus, which is used to treat thoracic obstruction, angina, cardiac failure, myocardial infarction, pulmonary heart disease, and some cerebral ischaemic diseases.
E3234	Trichosanthis Pericarpium Extract	Trichosanthis Pericarpium Extract is extracted from Trichosanthis Pericarpium, which can protects cardiomyocytes from Hypoxia/Reoxygenation Injury by Regulating PI3K/Akt/NO Pathway.
E2638	Tricine	Tricine (N-[Tris(hydroxymethyl)methyl]glycine) is a buffer component for separation of low molecular weight peptides.
S1117	Triciribine (API-2)	Triciribine (API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
S4114	Triclabendazole	Triclabendazole (CGA-89317,tcbz) is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.
S6444	Triclocarban	Triclocarban is an antibacterial agent common used in personal care products.
S3352	Tricosanoic acid	Tricosanoic acid is an aliphatic carboxylic acid that exhibits a strong hair-growing effect.
E2702	Tridecafluorohexane-1-sulfonic acid potassium salt	Tridecafluorohexane-1-sulfonic acid potassium salt is a perfluoroanionic surfactant, which is mainly used as a chromium mist inhibitor in electroplating, a wetting agent, and an additive in fluoroprotein foam fire extinguishing agents.
S6113	Tridecanoic acid	Tridecanoic acid (Tridecylic acid) is a 13-carbon saturated fatty acid found in many foods, some of which are nutmeg, muskmelon, black elderberry, and coconut.
S6223	Triethyl citrate	Triethyl citrate (Ethyl citrate, E1505, Citric acid ethyl ester) is used in pharmaceutical coatings and plastics.
E2967	Triethylenediamine	Triethylenediamine (1,4-Diazabicyclo[2.2.2]octane, DABCO), is a caged tertiary diamine commonly used as a strong hindered amine base in chemical synthesis. It is used in the synthesis of isoxazole derivatives via dehydration of primary nitro compounds in the presence of dipolarophiles. It can also be employed as a complexing ligand and as a catalyst.
S6585	Triethylenetetramine (Trientine) 2HCl	Triethylenetetramine (Trientine) 2HCl, a Cu(II)-selective chelator, is commonly used for the treatment of Wilson's disease.
S5856	Trifluoperazine	Trifluoperazine (NSC-17474, RP-7623, SKF-5019) is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.
S3201	Trifluoperazine 2HCl	Trifluoperazine (NSC-17474, RP-7623, SKF-5019) 2HCl is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM. Trifluoperazine also inhibits calmodulin (CaM).
S5565	Triflupromazine hydrochloride	Triflupromazine hydrochloride (Fluopromazine) is an antipsychotic medication of the phenothiazine class.
S1778	Trifluridine (NSC 75520)	Trifluridine (NSC 529182, NSC 75520, Viroptic, Trifluorothymidine, TFT) is an anti-herpesvirus antiviral agent by interacting viral DNA replication, used primarily on the eye.
S3200	Triflusal	Triflusal (UR1501) irreversibly inhibits the production of thromboxane-B2 in platelets by acetylating cycloxygenase-1.
E3280	Trifolium Pratense Extract	Trifolium Pratense Extract is extracted from Trifolium Pratense, which promotes anti-oxidant and anti-cancer effects.
S2427	Triglycidyl Isocyanurate (Teroxirone)	Triglycidyl Isocyanurate (Teroxirone, Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC) is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. Triglycidyl Isocyanurate is also used in various polyester powder coatings in the metal finishing industry.
S3220	Trigonelline	Trigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. Trigonelline inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. Trigonelline (Trigenolline) also inhibits the microtubule formation in RBL-2H3 cells.
S3802	Trigonelline Hydrochloride	Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.
E0018	Triheptanoin	Triheptanoin (API, IND106011, UX007, Glycerol trienanthate) is a synthetic, medium-chain triglyceride consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin is used for treatment of fatty acid oxidation disorders and GLUT1.
S4542	Trihexyphenidyl hydrochloride	Trihexyphenidyl hydrochloride (Benzhexol, Artane) is an antiparkinsonian agent of the antimuscarinic class.
S8389	Trilaciclib	Trilaciclib is a highly potent, selective and reversible cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor. Trilaciclib inhibits CDK4/cyclin D1 and CDK6/cyclin D3 with IC50 of 1 nM and 4 nM, respectively.
E4578	Trilaciclib dihydrochloride	Trilaciclib dihydrochloride(G1T28 dihydrochloride) is a potent inhibitor of CDK4/cyclin D1 and CDK6/cyclin D3 with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. Trilaciclib hydrochloride regulates cell proliferation and protects against chemotherapy toxicity in murine and canine bone marrow cells.
S9068	Trillin	Trillin (Disogluside, Diosgenin glucoside) is an active ingredient isolated from Trillium tschonoshii Maxim and acts as a potential anti-inflammatory drug for chronic hepatic inflammation.
S9064	Trilobatin	Trilobatin (P-Phlorizin), a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
S1404	Trilostane	Trilostane (WIN 24540) is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing’s syndrome.
S2085	Trimebutine	Trimebutine (Mebutin) is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.
S5507	Trimebutine maleate	Trimebutine maleate is the maleate salt form of trimebutine, which is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.
S5779	Trimetazidine	Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.
S4543	Trimetazidine dihydrochloride	Trimetazidine dihydrochloride (Yoshimilon, Kyurinett, Vastarel F) is a kind of drug for treatment of chronic ischemic disorders. It improves myocardial glucose utilization through inhibition of fatty acid metabolism, known as fatty acid oxidation inhibitor.
S5567	Trimethadione	Trimethadione is an oxazolidinedione anticonvulsant and often used to treat epileptic conditions that are resistant to other treatments.
S3129	Trimethoprim	Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
S6042	Trimethylamine N-oxide dihydrate	Trimethylamine N-oxide dihydrate, a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.
S5422	Trimethyloctadecylammonium bromide	Trimethyloctadecylammonium bromide (Octadecyltrimethylammonium bromide, OcTMAB, C18TAB) is a Dynamin I inhibitor with an IC50 of 1.9 μM and also inhibits Dynamin Ⅱ.
S3590	Triolein	Triolein is an inhibitor of metalloproteinase-1 (MMP-1) and reduces both the expression of IL-6 and ROS generation in irradiated keratinocytes.
E3067	Trionycis Carapax Extract	Trionycis Carapax Extract is obtained from Carapax Trionycis, of which Carapax Trionycis extracts with molecular weight less than 6 KD (CT6) down-regulates TNF-α, IL-1β and IL-6 expression in TGF-β1-treated HSC-T6, indicating the potential therapeutic effect of these extracts against liver fibrosis.
S3146	Tripelennamine HCl	Tripelennamine (Pyribenzamine) is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.
S6480	Triphosphopyridine nucleotide disodium salt	Triphosphopyridine nucleotide (NADP) serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
S5447	Triprolidine Hydrochloride	Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.
E3410	Tripterygium wilfordii Extract	Tripterygium wilfordii Extract is extracted from Tripterygium wilfordii, the effective constituent of which can induce autophagy via inhibition of the PI3K/AKT/mTOR signaling pathway.
S3604	Triptolide	Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. It functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. Triptolide (PG490) abrogates the transactivation function of heat shock transcription factor 1 (HSF1). Triptolide inhibits MDM2 and induces apoptosis through a p53-independent pathway.
S9416	Triptonide	Triptonide, isolated from the roots of Tripterygium wilfordii, can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin. It is also an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent.
S9045	Triptophenolide	Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A.
E2699	Tris(2-butoxyethyl) phosphate	Oral exposure to low-dose Tris (2-butoxyethyl) phosphate (TBEP) levels equivalent to tolerable daily intake may exacerbate allergic pulmonary inflammation by promoting a skewed T-helper 2 cell response, upregulation of ERα and dysregulation of both MLN and BM microenvironments.
E2698	Tris(2-ethylhexyl) phosphate	Tris (2-ethylhexyl) phosphate, a clear, viscous liquid, is used as a component of vinyl stabilizers, grease additives, and flame-proofing compositions; however, it is used primarily as a plasticizer for vinyl plastic and synthetic rubber compounds.
E2893	Triton X-114	Triton(TM) X-114 (Triton X-114) is a nonionic detergent used in biochemical applications for solubilizing and separation of intrinsic membrane proteins because of its reversible phase separation property.
S8432	Troglitazone	Troglitazone is a potent agonist for the peroxisome proliferator-activated receptor-(PPAR) that is a ligand activated transcription factor regulating cell differentiation and growth. Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells. Troglitazone prevents RSL3-induced ferroptosis and lipid peroxidation in Pfa1 cells.
S3665	Trolox	Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.
S4176	Trometamol	Trometamol(Tromethamine) is a proton acceptor used to treat acidemia.
S5300	Trometamol hydrochloride	Trometamol (THAM, Tromethamine, TRIS-HCL) hydrochloride, a proton acceptor, is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol rapidly restores pH and acid-base regulation in acidaemia.
E3251	Tropaeolum Majus Extract	Tropaeolum Majus Extract is extracted from Tropaeolum majus, which acts against bacterial infections and reduces apoptosis and DNA lesions in hypertonic conditions.
S1913	Tropicamide	Tropicamide(Ro 1-7683) is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM.
S8733	Tropifexor (LJN452)	Tropifexor (LJN452) is a novel and highly potent agonist of FXR with EC50 of 0.2 nM in HTRF assay. It shows no significant off-target activity against a broad panel of enzyme, ion channel, nuclear receptor, and GPCR (>10000-fold selectivity for FXR).
S4969	Tropine	Tropine (Pseudotropine, 3alpha-Tropanol) is a naturally occurring tropane alkaloid that serves as an intermediate in the synthesis of a variety of bioactive alkaloids, many of which have potent neurological actions.
S5687	Tropinone	Tropinone (3-Tropinone) is an alkaloid used for an intermediate in synthesis of atropine sulfate.
S5538	Tropisetron	Tropisetron (ICS 205-930) is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
S1898	Tropisetron HCl	Tropisetron HCl (ICS 205-930) is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.
S5688	Tropolone (NSC 89303)	Tropolone (NSC 89303, 2-Hydroxytropone, Purpurocatechol), a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion. It is able to inhibit ferric iron reduction by catecholates, lowering the redox potential of the iron couple.
S2549	Trospium chloride	Trospium chloride is a competitive muscarinic cholinergic receptor antagonist.
S3573	Trotabresib (CC-90010)	Trotabresib (CC-90010) is a reversible, orally active and central nervous system-penetrant inhibitor of bromodomain and extra-terminal (BET) proteins. CC-90010 is applied in the study for advanced solid tumors.
E2871	Trovafloxacin Mesylate	Trovafloxacin mesylate, a broad-spectrum quinolone antibiotic, is a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current.
S2369	Troxerutin	Troxerutin, a natural bioflavonoid isolated from Sophora japonica, has been reported to have many benefits and medicinal properties. Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.
S4128	Troxipide	Troxipide(KU 54) is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum.
S0174	TRPM8 antagonist 2	TRPM8 antagonist 2 (TRPM8 Antagonist) is a potent and selective antagonist of TRPM8 with IC50 of 0.2 nM that can be used for the pharmacological treatment of neuropathic pain syndromes.
E1061	TRULI	TRULI inhibits both Lats1 and Lats2 with a IC50 of 0.2 nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear.
E3420	Trumpet creeper Extract	Trumpet creeper Extract is extracted from Campsis, which has antibacterial and antifungal properties.
S7762	TRx0237 (LMTX) mesylate	TRx 0237 mesylate (LMTX, Hydromethylthionine) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
S6890	Trypan Blue	Trypan Blue (Visionblue, Diphenyl Blue, Direct Blue 14) is a colorimetric dye that stains dead cells with a blue color easily observed using light microscopy at low resolution.
E4452	Trypsin	Trypsin(Cocoonase) is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. It activates PAR2 and PAR4 and induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. It also promotes cell proliferation and differentiation and can be used in the research of wound healing and neurogenic inflammation.
S3627	Tryptamine	Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA).
E2153	TRYPTAMINE HYDROCHLORIDE	Tryptamine hydrochloride is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. Tryptamine is synthesized by decarboxylation of L-tryptophan and occurs endogenously at low concentrations in the mammalian brain. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds.
S4858	Tryptophol	Tryptophol (Indole-3-ethanol) is an aromatic alcohol found as a secondary product of alcoholic fermentation that induces sleep in humans.
S1045	TSA (Trichostatin A)	TSA (Trichostatin A) is an HDAC inhibitor with IC50 of ~1.8 nM in cell-free assays.
E3077	Tsaoko Fructus Extract	Tsaoko Fructus Extract is extracted from Tsaoko Fructus, which has antibacterial properties.
E0083	TSHR antagonist S37	TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).
S2966	TTK21	TTK21 is an activator of the histone acetyltransferases CBP/p300. It activates CBP/p300 histone acetyltransferase activity in a concentration-dependent manner with a maximal effect at a concentration of 275 µM. TTK21 passes the blood–brain barrier, induces no toxicity, and reaches different brain parts when conjugated to glucose-based carbon nanosphere (CSP).
S4627	TTNPB	TTNPB is a potent RAR agonist, and inhibits binding of [³H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.
S6536	TTP 22	TTP22 is a casein kinase 2 (CK2) inhibitor with an IC50 value of 100 nM. It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these kinases at 10 μM.
S2239	Tubacin	Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM in a cell-free assay, approximately 350-fold selectivity over HDAC1. Tubacin reduces the replication of the Japanese Encephalitis Virus via the decrease of viral RNA synthesis.
S8049	Tubastatin A	Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). Tubastatin A promotes autophagy and increases apoptosis.
S2627	Tubastatin A HCl	Tubastatin A HCl is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more).
S0709	Tubastatin A TFA	Tubastatin A TFA (Tubastatin A trifluoroacetate salt) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). Tubastatin A promotes autophagy and increases apoptosis.
S3814	Tubeimoside I	Tubeimoside I (Lobatoside H, TBMS1), a triterpenoid saponin, isolated from the tubers of Bolbostemma paniculatum, shows potent antitumor and antitumor-promoting effects.
S9433	Tubeimoside II	Tubeimoside II (Tubeimoside B), a natural triterpenoid saponin isolated from herb, show anti-inflammatory, antitumor, and antitumor-promoting effects.
S8095	Tubercidin	Tubercidin (7-deaza-adenosine), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.
S8362	Tucatinib	Tucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.
S8567	Tucidinostat (Chidamide)	Tucidinostat (Chidamide, HBI-8000, CS-055) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
S6775	TUG-891	TUG-891 is a potent and selective agonist of the long chain free fatty acid (LCFA) receptor 4 (FFA4/GPR120), which demonstrates both potential opportunity and possible challenges to therapeutic agonism.
S3712	Tulathromycin A	Tulathromycin A is a novel long-acting semi-synthetic tribasic macrocyclic antibiotic of the triamilide group and used for the treatment of pulmonary diseases of swine and cattle.
E1497	Tulmimetostat	Tulmimetostat (CPI-0209) is an orally bioavailable and selective inhibitor of EZH2 that has therapeutic potential for androgen receptor-dependent prostate cancer.
S6407	Tulobuterol hydrochloride	Tulobuterol is a long-acting β2-adrenergic receptor agonist that has bronchodilatory, anti-inflammatory, and antiviral activities.
S7894	Tunicamycin	Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.
S2694	Turofexorate Isopropyl (XL335)	Turofexorate Isopropyl (XL335, Fxr 450) is a potent, selective FXR agonist with EC50 of 4 nM, highly selective versus other nuclear receptors, such as LXR, PPAR, ER and etc. Phase 1.
D4026	Tusamitamab ravtansine	Tusamitamab Ravtansine (SAR-408701), is an antibody-drug conjugate (ADC) composed of CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule ) targeting antibody and a cytotoxic maytansinoid tubulin inhibitor DM4. TUSAMITAMAB RAVTANSINE has the potential for use in research of several solid tumors.
S9180	Tussilagone	Tussilagone, isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is used as a traditional oriental medicine for asthma and bronchitis. It shows anti-inflammatory activity in in vitro studies.
E1411	Tuvusertib	Tuvusertib (M1774, ATR inhibitor 1) is a potent ATR inhibitor, which exhibits anti-proliferative and anti-tumor effects in cancer cell lines.
S9786	Tuxobertinib (BDTX-189)	Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations with Kd of 0.2 nM, 0.76 nM, 13 nM and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. BDTX-189 exhibits anticancer activity.
S3576	TVB-3166	TVB-3166 is an orally-available, reversible, potent and selective inhibitor of fatty acid synthase (FASN) with IC50 of 0.042 μM in an in vitro biochemical assay. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth.
S8563	TVB-3664	TVB-3664 is a potent, selective, orally active and reversible inhibitor of fatty acid synthase (FASN) with IC50 of 0.018 μM and 0.012 μM for human and mouse cell palmitate synthesis, respectively.
S6702	Tween 80	Tween 80 is a polysorbate surfactant used for selective protein extraction and the isolation of nuclei from mammalian cell lines. Tween 80 has been used in drug vehicle solutions for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells.
S4621	Tween-20	Tween-20 (Polysorbates 20) is used in the formulation of biotherapeutic products for both preventing surface adsorption and as a stabilizer against protein aggregation.
S1590	TWS119	TWS119 is a GSK-3β inhibitor with IC50 of 30 nM in a cell-free assay; capable of inducing neuronal differentiation and may be useful to stem cell biology. GSK-3β inhibition triggers autophagy.
S5108	Tylosin	Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.
S3162	Tylosin tartrate	Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.
S4578	Tyloxapol	Tyloxapol (Triton WR1339) is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surfactant to aid liquefaction, removal of mucopurulent and bronchopulmonary secretions. It also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins.
S3625	Tyramine	Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) is a naturally occurring trace amine derived from the amino acid tyrosine and acts as a catecholamine releasing agent.
E4029	Tyramine hydrochloride	Tyramine Hydrochloride is a hydrochloride salt of the naturally occurring monoamine derived from the amino acid tyrosine. Tyramine acts as a catecholamine-releasing agent but cannot cross the blood-brain barrier.
L1800	Tyrosine Kinase Inhibitor Library	A unique collection of 654 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS).
S3773	Tyrosol	Tyrosol (4-Hydroxyphenylethanol, 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethanol) is an antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
S2895	Tyrphostin 9	Tyrphostin 9 (SF 6847, RG-50872) is firstly designed as an EGFR inhibitor with IC50 of 460 μM, but is also found to be more potent to PDGFR with IC50 of 0.5 μM.
S8024	Tyrphostin AG 1296	Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12.3 μM and 1.8 μM in Swiss 3T3 cells. Tyrphostin AG1296 induces dramatic apoptosis in A375R cells.
S2816	Tyrphostin AG 879	Tyrphostin AG 879 potently inhibits HER2/ErbB2 with IC50 of 1 μM, 100- and 500-fold higher selective to ErbB2 than PDGFR and EGFR.
S6805	Tyrphostin AG-528	Tyrphostin AG-528 (Tyrphostin B66) is a potent inhibitor of epidermal growth factor receptors (EGFR) and ErbB2/HER2 with IC50 of 4.9 μM and 2.1 μM, respectively. Tyrphostin AG-528 exhibits anticancer activity.
S0763	Tyrphostin AG1433	Tyrphostin AG1433 (AG1433, SU1433) is a selective platelet-derived growth factor receptor β (PDGFRβ) and vascular endothelial growth factor receptor 2 (VEGFR-2, Flk-1/KDR) inhibitor with IC50s of 5.0 μM and 9.3 μM, respectively.
S0324	Tyrphostin AG30 (AG30)	Tyrphostin AG30 (AG30), a potent and selective EGFR tyrosine kinase inhibitor, selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts.
S5594	α-Terpineol	α-Terpineol, a natural monoterpene, is the major component of essential oils of several species of aromatic plants such as Origanium vulgare L. and Ocimum canum Sims which are widely used for medicinal purposes. It is widely used in the manufacturing of cosmetics, soaps, perfumes, antiseptic agents and is considered one of the most frequently used fragrance compounds. α-TPN has anticholinergic action and can block the interaction between PGE2 and GM1 receptors and cholera toxin.
S4771	β-thujaplicin	β-Thujaplicin (β-TH, Hinokitiol, 4-Isopropyltropolone) is a toxic tropolone derivative present in the heartwood of western red cedar (Thuja plicata) and is used as a preservative and antimicrobial additive in a number of commercial goods. Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.
E0650	γ-Terpinene	γ-Terpinene (γ-TPN), a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly.,