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Catalog No.	Product Name	Information
S3925	(-)-Epicatechin gallate	(-)-Epicatechin gallate (ECG) is an inhibitor of cyclooxygenase-1 (COX-1) with IC50 of 7.5 μM.
S3922	(-)-epigallocatechin	(-)-Epigallocatechin, widespread in plants, has been shown to exhibit anti-tumor, anti-cancer and anti-inflammatory functions.
S4723	(-)Epicatechin	(−)Epicatechin (L-Epicatechin, (-)-Epicatechol) is a flavonoid present in cocoa, green tea and red wine. It is a strong antioxidant, has insulin mimic action and improves heart health.
S0371	(1E)-CFI-400437 dihydrochloride	CFI-400437 is a potent and selective polo-like kinase 4 (PLK4) inhibitor.
E2384	(E)-Akt inhibitor-IV	(E)-Akt inhibitor-IV is a PI3K-Akt inhibitor, with potent cytotoxic.
S3867	(E)-Cardamonin	(E)-Cardamonin (Alpinetin chalcone, cardamomin) is a naturally occurring chalcone with strong anti-inflammatory activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-κB inhibitor.
S0056	(E/Z)-BCI	(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.
S9850	(E/Z)-GO289	(E/Z)-GO289 potently and selectively inhibits casein kinase 2 (CK2) at an IC50 of 7 nM in vitro kinase assay.
E0381	(E/Z)-GSK-3β inhibitor 1	(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers, in which GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor with an IC50 of 4.19 nM.
S3384	(E/Z)-IT-603	(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603. IT-603 is a NF-κB family member c-Rel inhibitor with an IC50 of 3 μM in electrophoretic mobility shift assay (EMSA).
S6601	(±)-Equol	(±)-Equol, an isoflavandiol estrogen, is a metabolite of the soy isoflavones, daidzin and daidzein.
E0012	1-EBIO	1-EBIO (1-Ethylbenzimidazolinone, 1-Ethyl-2-benzimidazolinone）is an activator of Ca2+-sensitive K+ channels with an EC50 of 490 µM in T84 cells.
S4524	2-Ethoxybenzamide	2-Ethoxybenzamide (Ethenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.
S2429	2-Ethylaniline	2-Ethylaniline is an intermediate for pharmaceuticals, dyestuffs, pesticides, and other products.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S6057	2-Ethylbutyric Acid	2-Ethylbutyric Acid (2-ethyl hexanoic acid) is a chemical used to make paint dryers and plasticizers.
S6039	4-Ethyloctanoic acid	4-ethyloctanoic acid is identified from flue-cured Virginia tobacco and is mainly used as daily flavor, food flavor, industrial flavor, nutrient, stabilizers, surfactants and emulsifiers.
S6308	4-Ethylphenol	4-Ethylphenol (P-Ethylphenol, 4-Hydroxyphenylethane) is a phenolic compound produced in wine and beer by the spoilage yeast Brettanomyces.
S7370	4E1RCat	4E1RCat is a dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction, and inhibits the binding of eIF4G to eIF4E.
S7369	4EGI-1	4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with K_D of 25 μM. 4EGI-1 specifically inhibits the function of mTOR by blocking the activation of 4E-BP1. 4EGI-1 induces apoptosis.
E1255	5-Ethynyluridine	5-Ethynyluridine (5-EU) is a cell-permeable nucleoside and can be used to label newly synthesized RNA.
S9265	7-Epitaxol	7-Epitaxol (7-Epipaclitaxel) is the major derivative of taxol found in cells. Taxol (paclitaxel) is a well-known natural-source cancer drug.
S6627	E-4031 dihydrochloride	E-4031 is an experimental class III antiarrhythmic drug that blocks potassium channels of the hERG-type.
S7379	E-64	E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.
E1348	E-7386	E-7386 is a selective inhibitor which inhibits interaction between CBP/beta-catenin with IC50 value of 0.0484 μM in HEK293 cells.
S0012	E260	E260 (Fer and FerT inhibitor E260) is a Fer kinase and FerT inhibitor that selectively evokes metabolic stress in cancer cells by imposing mitochondrial dysfunction and deformation, and onset of energy-consuming autophagy which decreases the cellular ATP level.
S0716	E6446	E6446 is an inhibitor of Toll-like receptor (TLR) 7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro.
S6719	E6446 dihydrochloride	E6446 dihydrochloride is a specific Toll-like receptor 9 inhibitor.
S6649	E7046 (ER-886406)	E7046 (ER-886406, Palupiprant, AN0025) is a selective inhibitor of the prostaglandin E₂ (PGE₂) receptor EP4 with IC50 of 13.5 nM and Ki of 23.14 nM.
S9618	E7766 diammonium salt	E7766 diammonium salt, a macrocycle-bridged _STING agonist with a Kd of 40 nM, shows potent pan-genotypic and antitumor activities.
S6628	E7820	E7820 is a unique angiogenesis inhibitor with antitumor activities.
S8242	EAI045	EAI045 is an allosteric inhibitor that targets selected drug-resistant EGFR mutants but spares the wild-type receptor.
S2942	EB-3D	EB-3D is a potent and selective inhibitor of choline kinase α (ChoKα) with IC50 of 1 μM for ChoKα1. EB-3D induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells.
S4262	Ebastine	Ebastine(LAS-W 090,RP64305) is a potent H1-histamine receptor antagonist, used for allergic disorders.
S6530	EBE-A22	EBE-A22 is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.
S6676	Ebselen	Ebselen (DR 3305, SPI-1005, PZ-51, CCG-39161) is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.
S0472	EC330	EC330 is a steroidal inhibitor of leukemia inhibitory factor (LIF, an interleukin 6 class cytokine). EC330 inhibits the LIF/LIF-R signaling and blocks the promoting effects of LIF on growth and migration of cancer cells.
S4853	Ecabet sodium	Ecabet sodium (TA-2711, TA-2711E) is a widely employed mucoprotective agent for the treatment of gastric ulcers. Ecabet sodium inhibits the ability of Helicobacter pylori to induce neutrophil production of reactive oxygen species and interleukin-8, Ecabet sodium can also reduce apoptosis.
S3498	Ecamsule.2Na	Ecamsule.2Na is the Sodium salt form of Ecamsule. Ecamsule is an active ingredient of sunscreens that protects the skin from sunburn and erythema.
S0791	eCF506	eCF506 is a potent, selective and orally bioavailable inhibitor of Src tyrosine kinase with IC50 < 0.5 nM.
E3900	Echinacea Extract	Echinacea Extract is extracted from Echinacea, which boosts immune function, relieves pain, reduces inflammation, and has antiviral and antioxidant effects.
E3899	Echinacea Extract (flower)	Echinacea Extract (Flower) is extracted from purple coneflower, the flower of Echinacea purpurea, Echinacea angustifolia or Echinacea pallida. Purple coneflower is used as a treatment for respiratory tract infections and inflammatory conditions, including common cold, coughs, bronchitis, and inflammation of mouth and pharynx.
S3783	Echinacoside	Echinacoside, a natural polyphenolic compound, has various biological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative actions. Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche salsa, elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Echinacoside also has a remarkable antiosteoporotic activity.
E3487	Ecliptae Herba Extract	Ecliptae Herba Extract is extracted from Eclipta, which has an anti-osteoporotic effect.
S9403	Ecliptasaponin A	Ecliptasaponin A, a natural triterpenoid glucoside, has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-mesenchymal transition.
S5492	Econazole	Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.
S2535	Econazole nitrate	Econazole Nitrate (NSC 243115,Spectazole) is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.
S5591	Ectoine	Ectoine ( THP(B)) is a natural amino acid derivate with membrane stabilizing and inflammation reducing capacities. It is produced by bacteria living under extreme harsh environmental conditions where it serves as osmoregulatory compatible solute.
S1326	Edaravone	Edaravone (MCI-186) is a novel potent free radical scavenger that has been clinically used to reduce the neuronal damage following ischemic stroke.
E2636	EDC hydrochloride	EDC hydrochloride (1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, EDC·HCl) is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds.
S5721	Edetate calcium disodium	Edetate (EDTA) calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning.
S5706	Edetate Trisodium	Edetate Trisodium (EDTA trisodium salt, ethylenediaminetetraacetic acid) is the organic sodium salt of ethylenediaminetetraacetic acid (EDTA). EDTA is a chelating agent capable of removing a heavy metal, such as lead or mercury, from the blood.
S8524	Edicotinib(JNJ-40346527)	Edicotinib (JNJ-40346527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM.
S6733	Edonerpic maleate	Edonerpic maleate (T-817) is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).
S4429	Edoxaban	Edoxaban (DU-176b, Savaysa), an antithrombotic agent, is a selective, potent and orally active inhibitor of factor Xa (FXa) with Ki of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively.
S7280	Edoxaban tosylate Monohydrate	Edoxaban (DU-176b) is a selective factor Xa inhibitor with K_i of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug.
S5900	Edrophonium chloride	Edrophonium chloride is the chloride salt of edrophonium, which is a rapid-onset, short-acting, readily reversible inhibitor of acetylcholinesterase.
S1661	EdU (5-Ethynyl-2'-deoxyuridine)	EdU (5-Ethynyl-2'-deoxyuridine), a thymidine analogue, which can be incorporated into cellular DNA and the subsequent reaction of EdU with a fluorescent azide in a copper-catalyzed [3+2] cycloaddition ("Click" reaction) are developed as a method for detection of DNA synthesis. 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that is applicable to the synthesis of PROTACs.
S8496	EED226	EED226 is a potent, selective, and orally bioavailable a novel allosteric Polycomb repressive complex 2 (PRC2) inhibitor with an IC50 of 23.4 nM when the H3K27me0 peptide was used as substrate and an IC50 of 53.5 nM when the mononucleosome was used as the substrate. It directly binds to the H3K27me3 binding pocket of EED.
E1389	Eeyarestatin I	Eeyarestatin I is a potent inhibitor of endoplasmic reticulum-associated protein degradation (ERAD). Eeyarestatin I also inhibits Sec61 translocon.
S4263	Efaproxiral Sodium	Efaproxiral Sodium(RSR13 Sodium) is a synthetic allosteric modifier of hemoglobin, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. Efaproxiral Sodium is used for brain metastases originating from breast cancer.
S4685	Efavirenz	Efavirenz is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.
S9320	Efetaal	Efetaal has a fresh floral hyacinth note with a suggestion of muguet and green leaves.
S5025	Efinaconazole	Efinaconazole (KP-103) is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S4582	Eflornithine (DFMO) hydrochloride hydrate	Eflornithine (DFMO) hydrochloride hydrate inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours.
S4977	Efonidipine	Efonidipine (NZ-105) is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal.
S5898	Efonidipine hydrochloride monoethanolate	Efonidipine (NZ-105) hydrochloride monoethanolate is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. Efonidipine hydrochloride monoethanolate also suppresses aldosterone secretion from the adrenal.
E1332	EG-011	EG-011 is a potent Wiskott-Aldrich syndrome protein (WASP) activator.
E1119	EG00229	EG00229 is a neuropilin 1 (NRP1) receptor antagonist with an IC50 of 3 μM against VEGF-A binding to NRP1 b1 domain.
S0858	EG1	EG1 is a specific Paired box 2 (Pax2) inhibitor that targets the DNA binding domain and inhibits embryonic kidney development.
S8330	Eganelisib (IPI-549)	Eganelisib (IPI-549) is a potent inhibitor of PI3K-γ with >100-fold selectivity over other lipid and protein kinases. The biochemical IC50 for PI3K-γ is 16 nM.
S2250	EGCG ((-)-Epigallocatechin Gallate)	EGCG ((-)-Epigallocatechin Gallate) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.
E2748	EGCG Octaacetate	EGCG Octaacetate(AcEGCG) is a pro-drug of epigallocatechin-3-gallate (EGCG). EGCG have potent anti-oxidative, anti-mitotic and anti-angiogenic properties.
S0360	EGFR Inhibitor	EGFR inhibitor, a cell permeable, 4,6-disubstituted pyrimidine compound, is a highly selevtive inhibitor of EGFR kinase with IC50 of 21 nM. EGFR inhibitor directly depolymerizes microtubules and is used as a chemical probe to investigate both the EGFR pathway and microtubule dynamics.
E3563	Eggplant Extract	Eggplant Extract is extracted from Solanum melongena.
S4598	EGTA	EGTA is a specific calcium ion chelator.
E4448	EGTA tetrasodium	EGTA tetrasodium(Ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid tetrasodium salt) is a calcium chelator, used for the determination of calcium in the presence of magnesium. EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages.
S0256	Ehp-inhibitor-1	Ehp-inhibitor-1 (Ehp inhibitor 2) is an Eph family tyrosine kinase inhibitor that targets Eph receptors.
S7482	EHT 1864 2HCl	EHT 1864 2HCl is a potent Rac family GTPase inhibitor with K_d of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.
S7611	EI1	EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
S6476	Eicosapentaenoic Acid (EPA)	Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid with antiinflammatory properties, and is present in fish and fish oils, including salmon, cod, and krill oils.
S6466	Eicosapentaenoic acid ethyl ester	Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) is an omega-3 fatty acid agent that significantly reduces the triglyceride (TG) levels and improves other lipid parameters without significantly increasing the low-density lipoprotein (LDL) cholesterol levels.
S0833	EIDD-1931 (NHC)	EIDD-1931 (NHC) is an active metabolite of EIDD-2801, a promising COVID-19 inhibitor. EIDD-1931 (NHC) has broad spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and related zoonotic group 2b or 2c Bat-CoVs with average IC50 of 0.15 μM, as well as increased potency against a coronavirus bearing resistance mutations to the nucleoside analog inhibitor remdesivir.
E3008	Eight clawed Golden Dragon extract	Eight clawed Golden Dragon extract is extracted from Ardisia crispa(Thunb.)A.DC., which has anti-angiogenic effects.
S9849	EIPA (5-(N-Ethyl-N-isopropyl)-Amiloride)	EIPA (5-(N-Ethyl-N-isopropyl)-Amiloride) acts as an inhibitor of macropinocytosis and sodium-hydrogen exchangers(NHE) (IC50=0.033μg/mL). EIPA blocks the activity of Na(+)/H(+) exchanger, which are plasma membrane proteins implicated in all forms of macropinocytosis.
S9629	Elacestrant (RAD1901) Dihydrochloride	Elacestrant (RAD1901) Dihydrochloride is an orally available selective estrogen receptor degrader (SERD) with IC50 of 48 nM and 870 nM for ERα and ERβ, respectively.
S7772	Elacridar (GF120918)	Elacridar (GF120918, GW120918, GG918, GW0918) is a potent P-gp (MDR-1) and BCRP inhibitor.
E3609	Elaeagnus angustifolia Extract	Elaeagnus angustifolia Extract is extracted from the fruits of Elaeagnus angustifolia L.. Elaeagnus angustifolia fruit extract has acute and chronic anti-inflammatory activities.
S3720	Elafibranor	Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α(PPAR-alpha) and peroxisome proliferator-activated receptor-δ(PPAR-δ). It improves insulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation.
S4896	Elagolix Sodium	Elagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%).
S3357	Elaidic acid	Elaidic acid is a major trans fatty acid that inhibits cell viability, elevates cell apoptosis by enhancing oxidative stress. Elaidic acid can be used as a pharmaceutical solvent.
S9803	Elamipretide (MTP-131, SS-31)	Elamipretide (MTP-131, SS-31) is a cytochrome c peroxidase inhibitor. Elamipretide improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice.
S5652	Elbasvir	Elbasvir (MK8742) is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600 pmol/L, based on genotype.
E3345	ElderBerry Extract	ElderBerry Extract is extracted from the berries of Sambucus, which has been traditionally used to prevent and treat respiratory problems.
S5120	Elemicin	Elemicin (3,4,5-trimethoxyallylbenzene) is a constituent of the oleoresin and the essential oil of Canarium luzonicum. Elemicin is a constituent of natural aromatic phenylpropanoids present in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1(SCD1) activity in the liver by metabolic activation.
S8600	Elenbecestat	Elenbecestat (E2609) is a novel BACE1 inhibitor, demonstrating prolonged reductions in plasma beta-amyloid levels after single dosing.
S1052	Elesclomol (STA-4783)	Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand and inhibits FDX1-mediated Fe-S cluster biosynthesis.Elesclomol (STA-4783) is a potent copper ionophore and can be used in the research of copper-dependent cell death (cuproptosis).
S3180	Eletriptan HBr	Eletriptan (UK-116044) is a selective 5-HT1B and 5-HT1D receptor agonist with K_i of 0.92 nM and 3.14 nM, respectively.
E3281	Eleutherine Plicata Extract	Eleutherine Plicata Extract is extracted from Eleutherine plicata, which is a promising medicinal plant, and its activity is associated with cytotoxicity by binding to caspase-8.
S3841	Eleutheroside B	Eleutheroside B (syringin, Syringoside, Lilacin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties.
S8851	Elexacaftor (VX-445)	Elexacaftor (VX-445) is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector.This is a compound which is not chiral purity.
E0357	Eliapixant	Eliapixant (BAY1817080) is a highly potent and selective P2X3 receptor antagonist with a mean IC50 of 8 nM.
S7852	Eliglustat	Eliglustat (GENZ-112638) inhibits glucosylceramide synthase(GCS) (IC50=20 nM in intact MDCK cells), thus reducing the load of glucosylceramide influx into the lysosome.
S4433	Eliglustat hemitartrate	Eliglustat hemitartrate (Genz-112638, Eliglustat tartrate) is a potent, specific and orally active inhibitor of glucosylceramide synthase with IC50 of 24 nM.
S9864	Elimusertib (BAY-1895344)	Elimusertib (BAY-1895344) is a very potent and highly selective ATR (ataxia telangiectasia and Rad3-related) inhibitor with IC50 of 7 nM. Elimusertib potently inhibits proliferation of a broad spectrum of human tumor cell lines with median IC50 of 78 nM.
S8666	Elimusertib (BAY-1895344) hydrochloride	Elimusertib (BAY-1895344) hydrochloride is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.
S6731	Eliprodil (SL-820715)	Eliprodil (SL-820715) is a non-competitive NR2B-selective NMDA antagonist with IC50 value of 1 μM and is less potent for NR2A- and NR2C-containing receptors with IC50 > 100 μM.
S1327	Ellagic acid	Ellagic acid (Elagostasine, Gallogen) has antiproliferative and antioxidant property.
S6790	Ellipticine hydrochloride	Ellipticine Hydrochloride (NSC 71795, PZE) is a potent inhibitor of DNA topoisomerase II and forms covalent DNA adducts mediated by its oxidation with cytochromes P450 (CYP) and peroxidases. Ellipticine Hydrochloride is a natural product isolated from the Australian evergreen tree of the Apocynaceae family with antineoplastic activity.
E0460	ELN441958	ELN-441958 is a potent, neutral, competitive and selective bradykinin B1 receptor antagonist with a Ki of 0.26 nM against native human bradykinin B1 receptor.
S6798	ELN484228	ELN484228 is a cell-permeable blocker that targets α-synuclein, a key protein in Parkinson’s disease.
A2034	Elotuzumab (anti-SLAMF7)	Elotuzumab (anti-SLAMF7, BMS-901608, PDL063, HuLuc63) is a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7, also known as CS1, CD319, or CRACC). Elotuzumab shows a dual mechanism of action that includes the direct activation of natural killer (NK) cells and the induction of NK cell–mediated antibody-dependent cellular cytotoxicity.
S3725	ELR-510444	ELR-510444 is a novel microtubule disruptor with potential antivascular effects and in vivo antitumor efficacy, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells.
S9602	Elraglusib	Elraglusib(9-ING-41) is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with antitumor activity. 9-ING-41 induces apoptosis and cell cycle arrest at prophase by targeting centrosomes and microtubule-bound GSK3β.
E3761	Elsholtzia Ciliata Extract	Elsholtzia Ciliata Extract is obtained from Elsholtzia ciliata (Thunb.) Hyl.—an annual plant belonging to Lamiaceae Martinov family, which possesses anti-inﬂammatory, antiviral, antibacterial, antioxidant, anticancer, and vasorelaxant eﬀects.
S6200	Elsulfavirine	Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection.
S8397	Eltanexor (KPT-8602)	Eltanexor (KPT-8602, ONO-7706，ATG-016) is a second-generation, orally bioavailable XPO1 (also known as CRM1) inhibitor with IC50 values of 20−211 nM in 10 AML lines after 3 days exposure.
S4502	Eltrombopag	Eltrombopag (SB-497115), a member of the biarylhydrazone class, is a nonpeptide agonist of the thrombopoietin receptor (TpoR), used to treat chronic hepatitis C-associated thrombocytopenia and chronic immune (idiopathic) thrombocytopenia (ITP).
S2229	Eltrombopag Olamine	Eltrombopag Olamine is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).
S5230	Elubiol	Elubiol (dichlorophenyl imidazoldioxolan) is used as a cosmetic ingredient for the conditioning of oily skin, effective in oil control.
S2001	Elvitegravir	Elvitegravir is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM in cell-free assays, respectively.
S9620	Elzovantinib (TPX-0022)	Elzovantinib (TPX-0022, CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models.
S4423	Emamectin Benzoate	Emamectin Benzoate (EMB, MK-244) activates gamma-amino butyric acid (GABA) transporter. Emamectin Benzoate induces of reactive oxygen species (ROS)-mediated DNA damage and apoptosis.
A2041	Emapalumab (anti-IFNγ)	Emapalumab (anti-IFNγ), a monoclonal antibody directed against IFNγ, is the first global approval for the treatment of pediatric and adult patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory.
S2592	Emapunil (AC 5216)	Emapunil (AC-5216, 18 kiloDalton Translocator Protein, XBD173) is a novel mitochondrial benzodiazepine receptor/translocator protein (MBR/TSPO) ligand. Emapunil(AC-5216) showes high affinity for MBRs prepared from rat whole brain with Ki of 0.297 nM and IC50 of 3.04 nM and 2.73 nM at rat glioma cells and human glioma cells, respectively.
S9779	Emavusertib (CA-4948)	Emavusertib (CA-4948) is a potent and orally bioavailable inhibitor of interleukin-1 receptor-associated kinase 4/FMS-like Tyrosine Kinase 3 (IRAK4/FLT3) with anti-tumor activity.
S7025	Embelin	Embelin (Embelic Acid, NSC 91874), a quinone isolated from the Japanese Ardisia herb, is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.
S8824	EMD638683	EMD638683 is a highly selective inhibitor of serum- and glucocorticoid-inducible kinase 1 (SGK1) with IC50 of 3 μM. EMD638683 exhibits antihypertensive potency and anti-tumor activity.
S5659	Emedastine	Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (K1 = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).
S5647	Emedastine Difumarate	Emedastine Difumarate (Rapimine, Emedastine fumarate) is the difumarate salt form of emedastine, a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.
A2662	Emibetuzumab (Anti-HGFR / c-Met)	Emibetuzumab (Anti-HGFR / c-Met) is a humanized bivalent MET antibody targeting both HGF-dependent and HGF-independent MET pathway activation and tumor growth. It can be used in study of cancer. MW :144.56 KD.
E3816	Emilia Sonchifolia Extract	Emilia Sonchifolia Extract is extracted from Emilia sonchifolia, which is a potent immune response modulator.
S2977	EML 425	EML425 is a potent and selective CREB binding protein (CBP)/p300 inhibitor with IC50s of 2.9 and 1.1 μM, respectively.
E1213	Emlenoflast (MCC-7840)	Emlenoflast (MCC-7840), a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM.
S0467	Emodepside	Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.
S2295	Emodin	Emodin is a purgative resin, 6-methyl-1,3,8-trihydroxyanthraquinone, from rhubarb, the buckthorn and Japanese Knotweed (Fallopia japonica).
E0243	Emodin-8-glucoside	Emodin-8-glucoside (Emodin glucoside B, Anthraglycoside B, Emodin glucoside B) is an anthraquinone derivative isolated from Aloe vera, binds to minor groove of DNA.
E0107	EMPA	EMPA is a selective OX2 receptor antagonist and binds to human and rat OX2-HEK293 membranes with Kd values of 1.1 and 1.4 nM respectively.
S8022	Empagliflozin	Empagliflozin is a potent and selective SGLT-2 inhibitor with IC50 of 3.1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6. Phase 3.
S8214	Empesertib (BAY1161909)	Empesertib (BAY1161909, Mps1-IN-5), a derivative of triazolopyridine, is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase with IC50 of <1 nM. Empesertib has potential antineoplastic activity.
S7775	Emricasan (IDN-6556)	Emricasan (IDN-6556, PF 03491390, PF-03491390) is a potent irreversible pan-caspase inhibitor. Emricasan is an inhibitor of Zika virus infection.
S1704	Emtricitabine (FTC)	Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.
E1078	Emvododstat (PTC299)	Emvododstat(PTC299), a post-transcriptional inhibitor of pathogenic VEGF and dihydroorotate dehydrogenase(DHODH), inhibits VEGFA mRNA translation and abnormal cell proliferation. In HeLa cells PTC299 inhibits hypoxia-induced VEGFA protein production with an EC50 of 1.64 nM.
S9807	EN4	EN4, a covalent ligand that targets cysteine 171 (C171) of MYC, is selective for c-MYC over N-MYC and L-MYC. EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis.
E1575	EN450	EN450 is a cysteine-reactive covalent molecular glue degrader targeting NF-κB. It interacts with allosteric C111 in the E2 ubiquitin ligase UBE2D that induces the ternary complex formation between UBE2D and NFKB1. It exhibits anti-proliferative effects through a Cullin E3 ligase and proteasome-dependent mechanism.
E1698	EN460	EN460 is a small-molecule inhibitor of endoplasmic reticulum oxidation 1(ERO1), which is specific for the reduced active form of ERO1α and prevents re-oxidation. It also protects cells from erastin-induced ferroptosis.
S6650	EN6	EN6 is a novel covalent autophagy activator and targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase with an IC50 of 1.7 μM for recombinant human ATP6V1A protein.
S1941	Enalapril Maleate	Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
S1657	Enalaprilat Dihydrate	Enalaprilat (MK-422) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.
A2586	Enapotamab (Anti-AXL / UFO)	Enapotamab(Anti-AXL / UFO) is a highly specific rabbit polyclonal antibody that targets receptor tyrosine kinase AXL (UFO). It demonstrates potent activity in immunotherapeutic strategy for the treatment of sarcomas. MW :145.42 KD.
D4038	Enapotamab vedotin	Enapotamab vedotin (EnaV, HuMAX-AXL-ADC) is an AXL-specific human IgG1 antibody conjugated to the microtubule disrupting agent monomethyl auristatin E (MMAE) through a protease cleavable valine-citrulline (vc) linker.
S9656	Enarodustat (JTZ-951)	Enarodustat (JTZ-951) is a potent and orally active HIF prolyl hydroxylase inhibitor with IC50 of 0.22 μM for PHD2 and EC50 of 5.7 μM for EPO release from Hep3B cells. Enarodustat has the potential for the treatment of renal anemia.
S8205	Enasidenib (AG-221)	Enasidenib (AG-221) is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzyme.
S4929	Enasidenib(AG-221) Mesylate	Enasidenib (AG-221) mesylate is an orally available, selective and potent inhibitor of mutant isocitrate dehydrogenase 2 (IDH2).
S2957	Encenicline (EVP-6124) hydrochloride	Encenicline (EVP-6124) hydrochloride is a selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors.
S3431	Encequidar (HM30181)	Encequidar (HM30181, HM30181A) is a potent and selective inhibitor of the adenosine triphosphate-binding cassette transporter P-glycoprotein (P-gp).
E0361	Enclomiphene Citrate	Enclomiphene citrate is the trans isomer of clomiphene citrate and acts as a non-steroidal estrogen receptor antagonist.
S7108	Encorafenib	Encorafenib is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.
L8600	Endoplasmic Reticulum Stress Compound Library	A unique collection of 179 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening(HTS) and high content screening(HCS).
E0369	Endovion (NS 3728)	Endovion (NS 3728, SCO-101) is a potent anion channel inhibitor that blocks the Volume Regulated Anion Channels (VRAC).
S0712	Endoxifen E-isomer	Endoxifen E-isomer (E-Endoxifen), an E-isomer of Endoxifen and impurity in Endoxifen Z-isomer drug substance, exhibits antiestrogenic effects.
S7839	Endoxifen HCl	Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2.
D4053	Enfortumab vedotin-ejfv	Enfortumab vedotin-ejfv (Padcev) is an antibody-drug conjugate (ADC) composed of an fully human anti-Nectin-4 IgG1 kappa monoclonal antibody (AGS-22C3), conjugated to Monomethyl Auristatin E (MMAE), via a protease-cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl. Enfortumab vedotin-ejfv has the potential for use in research of urothelial carcinoma.
E0005	Enfuvirtide Acetate	Enfuvirtide Acetate (T20 Acetate, DP178 Acetate) is an HIV fusion inhibitor with ic50s of 13.63 nM and 30.21 nM on infection by HIV-1IIIB in MT-2 cells and HIV-1Bal in M7 cells, respectively.Solutions are unstable and should be fresh-prepared.
S9170	Engeletin	Engeletin (Dihydrokaempferol 3-rhamnoside), a bioactive flavonoid, has multiple biological activities such as anti-diabetic and anti-inflammatory effects. engeletin againsts LPS-stimulated endometritis in mice via negative regulation of pro-inflammatory mediators via the TLR4-regulated NF-κB pathway.
S8730	Enitociclib (BAY 1251152)	Enitociclib (BAY 1251152) is a potent PTEFb/CDK9 inhibitor with an IC50 value of 3 nM for CDK9 and an at least 50-fold selectivity against other CDKs in enzymatic assays. BAY1251152 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II and leading to the inhibition of gene transcription of various anti-apoptotic proteins.
S1181	ENMD-2076	ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to RET, SRC, NTRK1/TRKA, CSF1R/FMS, VEGFR2/KDR, FGFR and PDGFRα. ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0.025 to 0.7 μM, which induces apoptosis and G2/M phase arrest. Phase 2.
S2018	ENMD-2076 L-(+)-Tartaric acid	ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.
E3362	Enoki Mushroom Extract	Enoki Mushroom Extract is extracted from Flammulina velutipes, which helps in reducing blood sugar, blood pressure, and cholesterol.
S1756	Enoxacin	Enoxacin (AT-2266, CI919, Pd107779, NSC 629661) is an oral broad-spectrum fluoroquinolone antibacterial agent by inhibiting bacterial DNA gyrase and topoisomerase IV, used to treat a wide variety of infections.
S5209	Enoxacin Sesquihydrate	Enoxacin sesquihydrate (Enoxacin hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
S5415	Enoxaparin sodium	Enoxaparin sodium(PK 10169) is a low-molecular-weight heparin used to prevent and treat deep vein thrombosis or pulmonary embolism. It binds to and accelerates the activity of antithrombin III.
S2296	Enoxolone	Enoxolone (Glycyrrhetin) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.
S9931	Enpatoran Hydrochloride	Enpatoran (M5049) hydrochloride is a potent, orally active, and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM, respectively, in HEK293 cells.
S0501	Enpp-1-IN-1	Enpp-1-IN-1 (UUN28589, MV 658) is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1).
S3059	Enrofloxacin	Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.
S2934	Ensartinib dihydrochloride	Ensartinib dihydrochloride is a potent new-generation ALK inhibitor with high activity against a broad range of known crizotinib-resistant ALK mutations and CNS metastases. It potently inhibits both wild-type ALK and ALK variants (F1174, C1156Y, L1196M, S1206R, T1151, and G1202R mutants) with in vitro IC50s of <4 nM.
E1131	Ensitrelvir fumarate	S-217622 (Ensitrelvir fumarate) is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor with IC50 of 13 nM.
S4419	Ensulizole	Ensulizole (PBSA), a water soluble sunscreen ingredient, is a sulfonated UV absorber which is characterized by intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation.
S3147	Entacapone	Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.
S5246	Entecavir	Entecavir(BMS200475,SQ34676), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).
S1252	Entecavir Hydrate	Entecavir Hydrate (ETV, Baraclude,BMS200475 Hydrate,SQ34676 Hydrate), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).
S1053	Entinostat (MS-275)	Entinostat (MS-275, SNDX-275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM in cell-free assays, compared with HDACs 4, 6, 8, and 10. Entinostat induces autophagy and apoptosis. Phase 3.
S7523	Entospletinib (GS-9973)	Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13- to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.
S7998	Entrectinib	Entrectinib is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Entrectinib (RXDX-101) induces autophagy. Phase 2.
S1250	Enzalutamide	Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. Enzalutamide is shown to increase autophagy.
S1055	Enzastaurin	Enzastaurin is a potent PKCβ selective inhibitor with IC50 of 6 nM in cell-free assays, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3.
S6877	EOAI3402143	EOAI3402143 is a dose-dependent inhibitor of Usp9x, Usp24 and Usp5 that increases tumor cell apoptosis, and fully blocks or regresses myeloma tumors in mice.
S5521	Eosin Y Disodium	Eosin Y is a form of eosin. It is most commonly used as an acidic red stain for highlighting cytoplasm material in samples.
E1477	EP4-IN-1	EP4-IN-1 is a potent prostanoid EP4 receptor inhibitor. It exhibits prospects in tumor immunity and anti-inflammatory analgesia research.
S7910	Epacadostat (INCB024360)	Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).
S7587	Epacadostat (INCB024360) analogue	Epacadostat (INCB024360) analogue (INCB14943) is a potent, competitive IDO1 (indoleamine-(2,3)-dioxygenase) inhibitor with IC50 of 67 nM.
S2035	Epalrestat	Epalrestat is an aldose reductase inhibitor with IC50 of 72 nM.
S4877	Eperisone hydrochloride	Eperisone hydrochloride is muscle relaxant agent with antispasmodic effects. It is widely used in the treatment of patients with muscular contractures, low back pain or spasticity.
S6897	Epertinib hydrochloride	Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4 with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity.
S7955	EPI-001	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ∼6 μM and a selective PPAR-gamma modulator.
S8870	Epibrassinolide	Epibrassinolide is a brassinosteroid isolated from various plants and has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress.
L1900	Epigenetics Compound Library	A unique collection of 867 compounds with biological activity used for epigenetic research and associated assays.
S9078	Epigoitrin	Epigoitrin (Goitrin, BA-51-090278), the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.
E3829	Epimedium Brevicornu Extract	Epimedium Brevicornu Extract is extracted from Epimedium brevicornu Maxim, which has anti-inflammatory effects.
E3748	Epimedium Extract	Epimedium Extract is extracted from Epimedium, which has been preliminarily proven to show anti-osteoporotic and anti-inflammatory effects in OA.
S4253	Epinastine HCl	Epinastine (WAL-801CL) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
S2521	Epinephrine bitartrate	Epinephrine bitartrate (Adrenalinium) is an alpha- and beta-adrenergic receptor stimulator.
S3061	Epinephrine HCl	Epinephrine HCl (Adrenaline) is a hormone and a neurotransmitter.
S1223	Epirubicin HCl	Epirubicin HCl, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis.
P1116	Epitalon	Epitalon is an anti-aging agent and a telomerase activator, with an inhibitory effect of the on the development of spontaneous tumors in mice, as well as geroprotective actions and intranasal administration increases neuronal activity, also can be used for cancer, old age and Retinitis Pigmentosa.
S1707	Eplerenone	Eplerenone is a mineralocorticoid receptor antagonist, and blocks the action of aldosterone, used to control high blood pressure.
S9268	Epmedin B	Epmedin B (Epimedin B) is a component extracted from Epimedii Folium and may have antiosteoporotic activity.
S9269	Epmedin C	Epimedin C (Baohuoside VI), a flavonoid isolated from the herbs of Epimedium brevicornum Maxim, exhibits immunostimulatory and anticancer activities.
S1297	Epothilone A	Epothilone A is a paclitaxel-like microtubule-stabilizing agent with EC_0.01 of 2 μM.
S7038	Epoxomicin (BU-4061T)	Epoxomicin (BU-4061T, Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited at 100- and 1000-fold reduced rate. Epoxomicin promotes apoptosis.
S4137	Eprazinone 2HCl	Eprazinone (NSC 317935) is a mucolytic.
S7724	Eprenetapopt (APR-246)	Eprenetapopt (APR-246, PRIMA-1MET) is a small organic molecule that has been shown to restore tumour-suppressor function primarily to mutant p53 and also to induce cell death in various cancer types. APR-246 induces apoptosis and autophagy.
S3591	Eprinomectin	Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity.
S2419	Eprobemide	Eprobemide is a reversible monoamine oxidase A (MAO-A) inhibitor. Eprobemide acts as an antidepressant in Russia.
S4567	Eprodisate disodium	Eprodisate Disodium (NC-503) is the orally available disodium salt form of Eprodisate, a small-molecule, orally bioavailable, inhibitor of AA-amyloid fibrillogenesis.
S4102	Eprosartan Mesylate	Eprosartan(SKF-108566J) is a nonpeptide angiotensin II receptor antagonist, [³H]-eprosartan binds to the AT1 receptor with K_D of 0.83 nM in rat vascular smooth muscle cells.
S0343	Eprotirome (KB2115)	Eprotirome (KB2115) is a liver-selective agonist of thyroid hormone receptor (TR). Eprotirome is investigated for the potential treatment of dyslipidemias and obesity.
P1160	Epsilon-V1-2	Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor, which can inhibit the translocationof PKCε, but not α-, β-, and δ-PKC.
S0113	Eptapirone	Eptapirone (F11440) is a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.The affinity (pKi) of F11440 for 5-HT1A binding sites is 8.33.
P1011	Eptifibatide Acetate	Eptifibatide Acetate is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. A disulfide bridge forms between mercaptopropionyl and cysteine. Eptifibatide prevents platelet aggregation. One study shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes.
S7353	EPZ004777	EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM in a cell-free assay and demonstrates >1,200-fold selectivity for DOT1L over all other tested PMTs. EPZ004777 induces apoptosis.
S7004	EPZ005687	EPZ005687 is a potent and selective inhibitor of EZH2 with K_i of 24 nM in a cell-free assay, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.
S7805	EPZ011989	EPZ011989 is a potent, selective, orally bioavailable EZH2 inhibitor with K_i of <3 nM.
S7748	EPZ015666 (GSK3235025)	EPZ015666 (GSK3235025) is a potent, selective and orally bioavailable PRMT5 inhibitor with K_i of 5 nM, >20,000-fold selectivity over other PMTs.
S7820	EPZ020411 2HCl	EPZ020411 is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM.
E3716	Equisetum arvense Extract	Equisetum arvense Extract is drawed from Equisetum arvense L. (Equisetaceae), which contains many different compounds, and has hepatoprotective, antioxidant, and antidiabetic effects.
S2450	Equol	Equol ,a metabolite of soybeans, is an important isoflavone in humans，specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. Phase 2.
S6036	ER-000444793	ER-000444793 is a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening with IC50 of 2.8 μM.
S7242	Erastin	Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared.
E1874	Erastin2	Erastin2 is an inducer of ferroptosis. It also selectively inhibits xc(-) cystine/glutamate transporter. It induces ferroptosis in HT-1080, T98G, and A549 cells with the potential to treat neurodegenerative diseases.
E0344	ErbB2 inhibitor	ErbB-2 Inhibitor is a EGFR, ErbB2 and ErbB4 inhibitor with IC50s of 0.017 μM, 0.08 μM, 1.91 μM.
S8401	Erdafitinib	Erdafitinib is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Erdafitinib also binds to RET (c-RET), CSF-1R, PDGFR-α/PDGFR-β, FLT4, Kit (c-Kit) and VEGFR-2 and induces cellular apoptosis.
S1825	Erdosteine	Erdosteine (KW-9144,RV 144) is a mucolytic which is used in treatment of excessive viscous mucus. Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation.
E1017	ERG240	ERG240, a selective inhibitor of branched-chain aminotransferase 1 (BCAT1) with an IC50 of 0.1-1nM, leads to decreased oxygen consumption and glycolysis through the down regulation of IRG1 expression, which leads to decrease itaconate production in human macrophages.
S9137	Erianin	Erianin, a natural product derived from Dendrobium chrysotoxum, has been used as an analgesic in traditional Chinese medicine and is a potential anti-tumor agent. Erianin can inhibit IDO-induced tumor angiogenesis.
S8912	Eribulin Mesylate	Eribulin Mesylate, an analogue of the marine natural product halichondrin B, is a nontaxane completely synthetic microtubule inhibitor.
E3230	Eriocauli Flos Extract	Eriocauli Flos Extract is extracted from Eriocauli Flos, which is used in treating ophthalmic diseases, including diabetic retinopathy.
S9211	Eriocitrin	Eriocitrin (eriodictyol 7-rutinoside, Eriodictyol glycoside, Eriodictioside) is a flavone glycoside mainly found in lemon with antioxidant activity.
S9123	Eriodictyol	Eriodictyol, a flavonoid extracted from yerba santa, has anti-inflammatory and antioxidant activities and taste-modifying properties.
S7334	ERK5-IN-1	ERK5-IN-1 (XMD17-109) is a potent, and selective ERK5 inhibitor with IC50 of 162 nM.
S6786	ERK5-IN-2	ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50 of 0.82 μM and 3 μM for ERK5 and ERK5 MEF2D, respectively.
S7786	Erlotinib	Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib induces autophagy.
S1023	Erlotinib HCl	Erlotinib HCl is an EGFR inhibitor with IC50 of 2 nM in cell-free assays, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.
S9943	ErSO	ErSO activates the anticipatory unfolded protein response (a-UPR) with an IC50 of 20.3 nM in MCF-7 cells. ErSO induces rapid and selective necrosis of ERα-positive breast cancer cell lines in vitro.
S5657	Ertapenem sodium	Ertapenem Sodium (MK826) is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass.
S1598	Erteberel (LY500307)	LY500307 is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2.
S5413	Ertugliflozin	Ertugliflozin (MK-8835, PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0.877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1.
S4431	Ertugliflozin L-pyroglutamic acid	Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.
S5383	Erucic acid	Erucic acid (cis-13-docosenoic acid) is a monounsaturated omega-9 fatty acid used as mineral oil and a precursor to biodiesel fuel.
S6971	Ervogastat	Ervogastat (PF-06865571, DGAT2i) is a potent diacylglycerol acyltransferase 2 (DGAT2) inhibitor that reduces steatosis and hepatic triglyceride levels in non-alcoholic steatohepatitis (NASH).
E3157	Erycibes Caulis Extract	Erycibes Caulis Extract is extracted from Erycibes Caulis, which is used in the treatment of rheumatoid arthritis.
E3115	Erythrina Variegata Extract	Erythrina Variegata Extract is extracted from Erythrina variegate, is a folkloric medicine used for treating arthritic pain.
S4224	Erythritol	Erythritol(meso-Erythritol) is a sugar alcohol used as low-calorie sweetener.
S1635	Erythromycin	Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).
S7550	Erythromycin Cyclocarbonate	Erythromycin Cyclocarbonate(Davercin), derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
S5532	Erythromycin estolate	Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S4060	Erythromycin Ethylsuccinate	Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
S5227	Erythromycin thiocyanate	Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
S6165	Erythrosine B	Erythrosine B is cherry or melon-pink synthetic, primarily used for food coloring.
E0704	Esaxerenone (CS-3150)	Esaxerenone (CS-3150), a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, binds to mineralocorticoid receptor and inhibits (3)H-aldosterone binding to mineralocorticoid receptor with an IC50 value of 9.4 nM. Esaxerenone (CS-3150) also has the property of increasing the likelihood of albuminuria returning to normal levels and reducing progression of albuminuria to higher levels.
S4690	Escin	Escin (Aescin) is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).
S4064	Escitalopram Oxalate	Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with K_i of 0.89 nM.
S4711	Esculetin	Esculetin (Cichorigenin, Aesculetin) is a coumarin derivative found in various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lipoxygenases (LOs).
S2258	Esculin	Esculin (Aesculin) is a glucoside found in horse chestnuts.
S3382	ESI-05	ESI-05 (NSC 116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist with IC50 of 0.4 µM. ESI-05 (NSC 116966) inhibits cAMP-mediated activation of EPAC2 and EAPC2 mediated Rap1 activation.
S7499	ESI-09	ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA.
S4657	Eslicarbazepine Acetate	Eslicarbazepine Acetate (BIA 2093, Zebinix, Exalief, Stedesa, Aptiom), an antiepileptic drug, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.
S5778	Esmolol	Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.
S4100	Esmolol HCl	Esmolol (ASL8052) is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.
S1743	Esomeprazole magnesium	Esomeprazole Magnesium(NEXIUM) is a proton pump inhibitor to reduce gastric acid secretion through inhibition of H(+)/K(+)-ATPase in gastric parietal cells.
S2233	Esomeprazole sodium	Esomeprazole Sodium((S)-Omeprazole sodium, (-)-Omeprazole sodium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.
S1709	Estradiol	Estradiol (17β-estradiol, β-Estradiol, E2, 17β-Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
S4110	Estradiol Benzoate	Estradiol benzoate(β-Estradiol 3-benzoate) is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.
S4046	Estradiol Cypionate	Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.
S5872	Estradiol dipropionate	Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) is a semisynthetic, steroidal estrogen which has been used in hormone therapy for menopausal symptoms and low estrogen levels in women and in the treatment of gynecological disorders.
S3149	Estradiol valerate	Estradiol(E2V) is a synthetic ester used to treat menopausal symptoms and hormone deficiencies.
S2441	Estramustine phosphate sodium	Estramustine phosphate sodium (EMP, Emcyt, Estracyt) is an antitumour drug with a unique dual mode of action. Estrone and estradiol, products of the metabolism of estramustine phosphate sodium, have shown antigonadotrophic activity resulting in reduced testosterone levels. Estramustine(the cytotoxic metabolite produced by dephosphorylation of estramustine phosphate sodium) is an antiprostatic tumor drug with antimicrotubule effects.
S2466	Estriol	Estriol (NSC-12169) is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.
S0503	Estrogen receptor modulator 1	Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM) with pIC50 of 0.46. Estrogen receptor modulator 1 exhibits potential anti-tumor activity.
S1665	Estrone	Estrone is an estrogenic hormone.
S5288	Estropipate	Estropipate (Piperazine estrone sulfate, Estrone sulfate piperazine salt, Pipestrone) is a natural estrogenic substance composed of estrone sulfate and piperazine and is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms.
S0428	Etalocib	Etalocib(LY293111, VML295) is a leukotriene B4 receptor (LTB4R) antagonist that blocks activation of human neutrophils.
A2991	Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3))	Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) is an IgG1 monoclonal antibody targeting αvβ3 integrin. It inhibits angiogenesis and melanoma tumor growth and can be used to research anticancer. MW :144.18 KD.
S6616	ETC-159	ETC-159 (ETC-1922159) is an orally available, potent porcupine inhibitor with an IC50 of 2.9 nM for inhibiting β-catenin reporter activity in STF3A cells.
S6658	ETC-206 (AUM 001)	ETC-206 (AUM 001, ETC-1907206) is an orally available highly selective small-molecule MNK 1/2 inhibitor with IC50s of 64 nM and 86 nM, respectively.
P1110	Etelcalcetide HCl	Etelcalcetide HCl (AMG 416) is a novel synthetic peptide agonist of the calcium-sensing receptor (CaSR) composed of a linear chain of seven d-amino acids with a d-cysteine linked to an l-cysteine via a disulfide bond.
S4945	Ethacridine lactate	Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
S4196	Ethacridine lactate monohydrate	Ethacridine lactate monohydrate(Acrinol monohydrat) is an aromatic organic compound based on acridine used as an antiseptic agent.
S5847	Ethacrynate Sodium	Ethacrynate Sodium (ethacrynic acid sodium) is the sodium salt form of ethacrynic acid, which inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.
S5561	Ethacrynic Acid	Ethacrynic Acid is a loop or high ceiling diuretic used for the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.
S4004	Ethambutol 2HCl	Ethambutol 2HCl (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
S4152	Ethamsylate	Ethamsylate (Etamsylate) is a haemostatic drug, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion.
S6210	Ethanolamine hydrochloride	Ethanolamine (2-Aminoethanol) is a viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin.
S3689	Ethidium bromide	Ethidium Bromide (Homidium bromide, EtBr, EB) is an intercalating agent which resembles a DNA base pair and commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
S1625	Ethinyl Estradiol	Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.
S1777	Ethionamide	Ethionamide (Bayer 5312) is an antibiotic used in the treatment of tuberculosis.
S2611	Ethisterone	Ethisterone(17α-Ethynyltestosterone) is a progestogen hormone being considered to treat prostate cancer.
S3707	Ethopabate	Ethopabate (ETP, Ethyl pabate) is a coccidiostat that is frequently used to prevent and treat coccidiosis in chickens.
S4626	Ethosuximide	Ethosuximide(Zarontin) is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker.
S9460	Ethotoin	Ethotoin (Peganone) is a hydantoin derivative and an orally active anticonvulsant agent. It also exerts an antiepileptic effect and can be used in epilepsy research.
S5511	Ethyl (triphenylphosphoranylidene) acetate	Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.
S3682	Ethyl 3-Aminobenzoate methanesulfonate	Ethyl 3-Aminobenzoate (Ethyl m-Aminobenzoate, NSC 93790, Tricaine) can block the generation of action potentials via voltage-dependent Na+-channels and usually used for anesthesia, sedation, or euthanasia of fish.
S9350	Ethyl 4-Methoxycinnamate	Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S6024	Ethyl acetoacetate	Ethyl acetoacetate, found in coffee and coffee products as well as in strawberry and yellow passion fruit juice, is a flavouring agent used as a chemical intermediate in the production of a wide variety of compounds.
S5640	Ethyl caffeate	Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
S5349	Ethyl chrysanthemumate	Ethyl chrysanthemate (Chrysanthemic acid ethyl ester) is an allelochemical compound used as an attractant.
S9336	Ethyl Coumarin-3-carboxylate	Ethyl coumarin-3-carboxylate occupies an important position in the organic synthesis and is used in production of biologically active compounds.
S3855	Ethyl ferulate	Ethyl ferulate (Ferulic acid ethyl ester) is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiproliferative activities.
S5550	Ethyl gallate	Ethyl gallat (Phyllemblin, gallic acid ethyl ester), which could be found naturally in a variety of plant sources, is a food additive with antimicrobial activity. Ethyl gallat activates the death receptor-dependent pathway of apoptosis by enhancing the expression of caspases-8, -9, and -3 and the Bcl-2 interacting domain (Bid).
S6335	Ethyl maltol	Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one, 2-Ethyl pyromeconic acid) is a common flavourant in some confectioneries.
E2954	Ethyl methanesulfonate	Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. It induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes.
S5367	Ethyl Oleate	Ethyl Oleate (Oleic acid ethyl ester) is a fatty acid ester formed by the condensation of oleic acid and ethanol, usually used as a solvent for pharmaceutical drug preparations.
S9372	Ethyl palmitate	Ethyl palmitate (Ethyl hexadecanoate, Palmitic acid ethyl ester) is a long-chain fatty acid ethyl ester that is used as a hair- and skin-conditioning agent.
S6222	Ethyl potassium malonate	Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
S6243	Ethyl pyruvate	Ethyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.
S3993	Ethyl Vanillate	Ethyl vanillin (Bourbonal, Ethylprotal), a vanillin analog, is a flavouring agent and a fungicidal agent that exhibits strong antioxidant activity. Ethyl Vanillate inhibits 17β-HSD2 with an IC50 1.3 µM.
S9337	Ethyl vanillin acetate	Ethyl vanillin acetate is acectate form of ethyl vanillin, which is a flavorant and is used in the production of chocolate.
S6350	Ethylenediaminetetraacetic acid	Ethylenediaminetetraacetic acid (EDTA) is a chelating agent commonly used in protein purification, to decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification and to inhibit protease activity. It can also decrease the formation of disulfide bonds and can also inhibit complement activation; protein protection in some immunoassays
S4525	Ethylparaben	Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
S4568	Ethylvanillin	Ethylvanillin (Ethylprotal, Bourbonal, Rhodiarome) is the organic flavorant. It is about three times as potent as vanillin and used in the production of chocolate.
S3160	Ethynodiol diacetate	Ethynodiol diacetate (8080 CB,Ethynodiol acetate) is one of the first synthetic progestogens used in contraceptive pills.
S1857	Etidronate	Etidronate is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification.
S1328	Etodolac	Etodolac(AY-24236) is a nonsteroidal anti-inflammatory drug (NSAID) and a COX inhibitor, used for the treatment of inflammation and pain.
S6742	Etofenamate	Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.
S4264	Etofibrate	Etofibrate is a combination of clofibrate and niacin, used to treat hyperlipemia.
S5029	Etofylline	Etofylline (Aethophyllinum, Cordalin, Oxyphylline) is a N-7 substituted theophylline derivative used as a bronchodilator.
A2668	Etokimab (Anti-IL-33)	Etokimab (Anti-IL-33) is a humanized monoclonal antibody that targets IL-33. It can be used for the research of atopic dermatitis. MW :146.56 KD.
S8244	Etomoxir sodium salt	Etomoxir sodium salt ((R)-(+)-Etomoxir sodium salt) is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. Etomoxir enhances palmitate-induced cell apoptosis.
S4673	Etonogestrel	Etonogestrel (Implanon, Nexplanon, 3-Oxodesogestrel, 3-keto-Desogestrel) is a synthetic form of the naturally occurring female sex hormone progesterone. It binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression.
S1225	Etoposide	Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding. Etoposide induces autophagy, mitophagy and apoptosis.
S4651	Etoricoxib	Etoricoxib (Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia) is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties.
S6802	Etosalamide	Etosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties.
S8050	ETP-46464	ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
E2363	Etrasimod(APD334)	Etrasimod(APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an EC50 value of 1.88 nM in CHO cells.
S3080	Etravirine	Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
S4699	Etretinate	Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato,Ro 10-9359) is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.
S9608	Etrumadenant (AB928)	Etrumadenant (AB928, A2aR/A2bR antagonist-1) is a novel dual A2aR/A2bR antagonist with Kd of 1.4 nM and 2 nM for A2aR and A2bR, respectively.
S3761	Eucalyptol	Eucalyptol (NSC 6171, 1,8-Cineol, 1,8-cineole, 1,8-Epoxy-p-menthane, 1,8-Oxido-p-menthane, Cineol, Cineole) is a monoterpenoid oil present in many plants, principally the Eucalyptus species, and has been reported to have anti-inflammatory and antioxidative effects. Eucalyptol controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
E3817	Eucalyptus Globulus Fruit Extract	Eucalyptus Globulus Fruit Extract is extracted from the fruit of Eucalyptus globulus, which has anticancer activity.
E3004	Eucalyptus Leaf Extract	Eucalyptus Leaf Extract is extracted from the leaves of Eucalyptus spp..
E3174	Eucommia Extract (Bark, Branch and Leaf)	EucommiaExtract (Bark, Branch and Leaf) is extracted from bark, branch and leaf of Eucommiae Cortex, a rare, nourishing medicinal herb that is native in China, which has good effect in the treatment of hypertension.
E3175	Eucommia Ulmoides Male Flower Extract	Eucommia Ulmoides Male Flower Extract is extracted from the male flower of Eucommia Ulmoides, which exhibits an antihypertensive action.
E3173	Eucommiae Cortex Extract	Eucommiae Cortex Extract is extracted from bark ofEucommiae Cortex, a rare, nourishing medicinal herb that is native in China, which has good effect in the treatment of hypertension.
S4706	Eugenol	Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol) is a naturally occuring scent chemical found in clove oil and other plants. The physiologic effect of eugenol is by means of increased Histamine Release, and cell-mediated Immunity.
S9377	Eugenyl acetate	Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.
S4261	EUK 134	EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
E3237	Euonymus alatus Sieb Extract	Euonymus alatus Sieb Extract is extracted from Euonymus alatus Sieb, improves the glucose uptake rate in coordination with low density insulin on adipocytes.
S3846	Eupatilin	Eupatilin (NSC 122413), a major flavonoid from Artemisia plants, possesses various beneficial biological effects including anti-inflammation, anti-tumor, anti-cancer, anti-allergy, and anti-oxidation activity. Eupatilin, a lipophilic flavonoid isolated from Artemisia species, is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.
S9410	Euphorbia factor L1	Euphorbia factor L1, a diterpenoid isolated from Euphorbia lathyris, inhibits osteoclastogenesis and induces osteoclast apoptosis.
S9279	Euphorbia factor L3	Euphorbia factor L3 (5,15-Diacetyl-3-benzoyllathyrol), belonging to the lathyrane diterpenoids isolated from Caper Euphorbia Seed, shows potent cytotoxicity and induces apoptosis via the mitochondrial pathway in A549 cells.
E3860	Euphorbia Helioscopia Extract	Euphorbia Helioscopia Extract is extracted from Euphorbia helioscopia L., which has been used in the treatment of various diseases, including edema, phlegm and cough, malaria, dysentery, scab, tuberculous fistula, osteomyelitis, and cancer.
E3191	Euphorbia Hirta Extract	Euphorbia Hirta Extract is extracted from Euphorbia Hirta, which is used in the treatment of gastrointestinal disorders.
E3552	Euphorbia lathyris Extract	Euphorbia Lathyris Extract is extracted from the seed of Euphorbia lathyris, which havs antitumor activity.
E3148	Euphorbiae Humifusae Herba Extract	Euphorbiae Humifusae Herba Extract is extracted from Euphorbiae Humifusae, which induces apoptosis in Hep3B hepatocarcinoma cells and can be a treatment for hepatocellular carcinoma.
S3832	Euphorbiasteroid	Euphorbiasteroid (Euphorbia factor L1), a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a dose-dependent manner. Euphorbiasteroid is a tricyclic diperpene of Euphorbia lathyris L., inhibits tyrosinase, and increases the phosphorylation of AMPK, with anti-cancer, anti-virus, anti-obesity and multidrug resistance-modulating effect.
E3702	Eupolyphage sinensis Walker Extract	Eupolyphage sinensis Walker Extract is aqquired from the aqueous extract of Eupolyphaga sinensis Walker, which shows a potency to potentiate immune responses in mice.
S0846	Euquinine	Euquinine is generally used as a febrifuge, antimalarial, and tonic.
E3558	Euryale ferox Extract	Euryale ferox Extract is derived from Euryale ferox Salisb, the seed from Gordon Euryale, which has anti-diabetic, antioxidant, and anti-hyperlipidemic effects.
S2925	Evacetrapib (LY2484595)	Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
S4716	Evans Blue	Evans Blue (Direct Blue 53,C.I.23860) is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist.
E0053	Evatanepag	Evatanepag (CP-533536 free acid) is a potent and selective EP2 receptor agonist with an IC50 of 50 nM for rEP2.
S1120	Everolimus	Everolimus is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation.
A2049	Evinacumab(anti-ANGPTL3)	Evinacumab is a monoclonal antibody that targets, binds to, and pharmacologically inhibits ANGPTL3, which can act as a complementary agent to other LDL-C lowering regimens for patients aged 12 or older with HoFH.
S8777	Evobrutinib	Evobrutinib is a highly selective BTK inhibitor with an IC50 of 37.9 nM. It has potential anti-neoplastic activity.
E0359	Evocalcet	Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
E3589	Evodia Lepta Bark Extract	Evodia Lepta Bark Extract is extracted from the bark of Melicope pteleifolia, which has anti-inflammatory activity.
S2382	Evodiamine	Evodiamine (Isoevodiamine), an alkaloid extract from the fruit of Evodiae Fructus exhibits antitumor activities against the human tumor cells. It is shown to inhibit NF-κB activation through suppression of IkB kinase activity.
S9563	Evodine	Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor.
S2757	Evofosfamide (TH-302)	Evofosfamide (TH-302) is a selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.
A2043	Evolocumab (anti-PCSK9)	Evolocumab (anti-PCSK9) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR. Evolocumab can be used for the research of hypercholesterolemia and atherosclerotic cardiovascular diseases.
S8654	ex229 (compound 991)	EX229 (compound 991) is a potent AMPK activator that is 5-10-fold more potent than A769662 in activating AMPK.
E1649	Exarafenib	Exarafenib(KIN-002787, KIN-2787, RAF/KIN_2787) is an orally-available, selective inhibitor of pan-RAF. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. KIN-2787 exhibits low nanomolar to picomolar potency against RAF1, BRAF, and ARAF with an IC50 of 0.06-3.46 nM with minimal activity towards non-RAF kinases.
S8999	Exatecan Mesylate	Exatecan Mesylate (DX-8951f) is a water-soluble and non-pro-drug analog of camptothecin and shows significant topoisomerase I inhibition with IC50 of 0.975 μg/ml.
S1196	Exemestane	Exemestane is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.
P1046	Exenatide Acetate (Exendin-4)	Exenatide Acetate (Exendin-4), a 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus.
S6800	Exo1	Exo1 (2-(4-Fluorobenzoylamino)-benzoic acid methyl ester) is a reversible inhibitor of exocytosis, induces a rapid collapse of the Golgi to the endoplasmic reticulum and the rapid release of ADP-ribosylation factor (ARF) 1 from Golgi membranes.
E3374	Exocarpium Citri Rubrum Extract	Exocarpium Citri Rubrum Extract is extrcated from Exocarpium Citri Rubrum, which protects the stomach and eliminates dampness and phlegm.
L8800	Exosome Secretion Related Compound Library	A unique collection of 52 exosome secretion related compounds used for high throughput screening(HTS) and high content screening(HCS).
L3600	Express-Pick Library	A unique collection of 3010 chemical compounds featured different core structures and structural diversities respectively for high throughput screening (HTS) and high content screening (HCS).
E3547	Extract of Scandent Schefflera Stem and Leaf	Extract of Scandent Schefflera Stem and Leaf is isolated from Scandent Schefflera Stem and Leaf
E3772	Eyebright Extract	Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
S9698	Ezatiostat	Ezatiostat, a tripeptide analog of glutathione, is a peptidomimetic inhibitor of Glutathione S-transferase P1-1 (GSTP1-1). Ezatiostat activates c-Jun NH2 terminal kinase (JNK1) and ERK1/ERK2 and induces apoptosis.
S1655	Ezetimibe (SCH-58235)	Ezetimibe (SCH-58235) is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.
E1179	EZM0414	EZM0414 is a potent, selective, and orally bioavailable inhibitor of Histone-lysine N-methyltransferase SETD2.
S0418	Ezutromid	Ezutromid (SMT C1100,BMN 195,VOX-C1100) is a first-in-class, orally active benzoxazole utrophin modulator with an EC50 of 0.91 μM which can be used for the research Duchenne muscular dystrophy (DMD), also inhibits CYP1A2 enzymic activity in human liver microsomes (HLM) with an IC50 of 5.4 μM.
S6957	β-Elemene	β-Elemene ((-)-β-Elemene, Levo-β-elemene) is a sesquiterpene compound extracted from the herb Curcuma Rhizoma with antitumor activities. β-elemene can inhibit cell proliferation, arrest the cell cycle, and induce cell apoptosis or autophagy.
S5236	β-Estradiol 17-Acetate	β-Estradiol 17-Acetate is a metabolite of estradiol which is an estrogen steroid hormone and the major female sex hormone.