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Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation

94 views | Oct 05 2023

Nr4a1 promotes renal fibrosis by activating p38 MAPK, as evidenced by its upregulation in a mouse model of renal interstitial fibrosis, its correlation with fibrotic protein levels, and the exacerbation of fibrosis by Nr4a1 activation and its inhibition by p38 MAPK blockade. [Read the Full Post]