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5-alpha Reductase

[Androgens and Parkinson's disease: the role in humans and in experiment]

82 views | Feb 05 2023

Parkinson's disease is more common in men than women and studies suggest a role of sex hormones in its pathogenesis, but current drug therapy with androgens, androgen precursors, antiandrogens and drugs that modify androgen metabolism have not shown sufficient effectiveness and 5α-reductase inhibitors show promise for neuroprotection and anti-dyskinetic properties, but more research is needed. [Read the Full Post]

GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS Axis in hepatocellular carcinoma

0 views | Mar 10 2017

Gu YJ et al found that GRP78 confers the resistance to 5-FU by up-regulating the c-Src/LSF/TS axis via its ATPase domain [Read the Full Post]