Category

Archives

Crusted scabies in AIDS patient, a clinical challenge to be sorted out with a simple bedside test

Norwegian or crusted scabies is a highly contagious severe variant of scabies described first among leprosy patients in Norway in 1848 by Boeck and Danielsen. Herein, we report a case of crusted scabies in an AIDS patient with large hyperpigmented macules covered with thick crusts present over the axilla, inguinal region, and gluteal region. Treatment started immediately with ivermectin, permethrin, and keratolytics after doing KOH microscopy. Mite population may exceed 1 million/person. Hence, it is highly infectious and can set off epidemics of scabies in home or institutions.

 

Comments:

An AIDS patient presented with crusted scabies, a highly contagious severe form of scabies characterized by large hyperpigmented macules with thick crusts that can cause epidemics in homes or institutions; treatment with ivermectin, permethrin, and keratolytics was initiated immediately.

Related Products

Cat.No. Product Name Information
S1351 Ivermectin Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. Ivermectin induces autophagy through the AKT/mTOR signaling pathway and mitophagy.

Related Targets

AChR HIV Mitophagy P2 Receptor COVID-19 Autophagy Chloride Channel