Choose Your Country or Region

Category

PI3K/Akt/mTOR
- PI3K
- mTOR
- Akt
- GSK-3
- ATM/ATR
- PDK
- AMPK
- DNA-PK
- MELK
- PTEN
- PDPK1
- PP2A
- PIKfyve
- PI4K
Epigenetics
- HDAC
- AMPK
- PARP
- JAK
- Pim
- HIF
- PKC
- Aurora Kinase
- Sirtuin
- Histone Acetyltransferase
- Epigenetic Reader Domain
- Histone Methyltransferase
- Histone Demethylase
- DNA Methyltransferase
- SAM MTase
- PPMTase
- WDR5
- SMYD
- DOT1
- HNMT
- SETD
- NSD
- G9a/GLP
- FTO
- MLL
- MicroRNA
- JMJD
- PRMT
- EZH1/2
- PAD
- LSD1
- COMT
Methylation
- DNA Methyltransferase
- PRMT
- NSD
- EZH1/2
- FTO
- LSD1
- MAT2A
- NNMT
- COMT
- SAM MTase
- PPMTase
- WDR5
- SMYD
- DOT1
- HNMT
- SETD
- G9a/GLP
- MLL
- JMJD
Immunology & Inflammation
- CD markers
- PD-1/PD-L1
- TNF-alpha
- COX
- CCR
- Histamine Receptor
- IL Receptor
- NOD
- CXCR
- MALT
- LTR
- TLR
- NOS
- Nrf2
- ROS
- NADPH-oxidase
- Anti-infection
- AhR
- IDO/TDO
- gp120/CD4
- Immunology & Inflammation related
- Nur77
- Galectin
- Complement System
- Prostaglandin Receptor
- Glutathione
- SPHK
- β-lactamase
- PGES
- TBK1
- IFN
- IRAK
- FLAP
- Arginase
- Interleukins
- Pyroptosis
- NLRP3
- Neuraminidase
- cGAS
- PGDS
- SIK
- TRIF
- FKBP
- PKR
- AKR1C
- Parasite
- TpoR
- MmpL3
- Heme Oxygenase
- Antioxidant
- MyD88
- eIF
- MIF
- STING
Protein Tyrosine Kinase
- VEGFR
- MEK
- EGFR
- PDGFR
- c-Met
- HER2
- IGF-1R
- FLT3
- FGFR
- Bcr-Abl
- c-Kit
- Src
- ALK
- Syk
- Tie-2
- FAK
- c-RET
- DYRK
- Ephrin receptor
- CSF-1R
- ACK
- Trk receptor
- BTK
- Tyro3
- Pyk2
- ROS1
- DDR
- RON
- Fer kinase
- ETK/BMX
- Mertk
- Axl
Angiogenesis
- VEGFR
- JAK
- EGFR
- PDGFR
- HER2
- FLT3
- FGFR
- HIF
- VDA
- Bcr-Abl
- Src
- ALK
- Syk
- FAK
- BTK
Apoptosis
- PD-1/PD-L1
- STAT
- Bcl-2
- Caspase
- p53
- TNF-alpha
- MDM2/MDMX
- Survivin
- Ras
- c-RET
- IAP
- RIP kinase
- PERK
- ASK
- Ferroptosis
- Myc
- Thymidylate Synthase
- Pyroptosis
- DAPK
- Nur77
- PKD
- PFKFB
- cytohesin
- FKBP
- Apoptosis related
- OXPHOS
- Heme Oxygenase
- TRADD
- Bcl-6
Autophagy
- CXCR
- Nrf2
- LRRK2
- Autophagy
- FKBP
- Mitophagy
- Heme Oxygenase
- OGA
- Beclin
- LC3
- cGAS
- ULK
ER stress & UPR
- JNK
- HSP (HSP90)
- ASK
- ROS
- PERK
- PDI
- IRE1
- eIF
- PKR
- Antioxidant
- ATF-6
JAK/STAT
- JAK
- STAT
- EGFR
- Pim
MAPK
- S6 Kinase
- MEK
- Raf
- p38 MAPK
- JNK
- Ras
- MNK
- KLF
- TAK1
- ERK
- TOPK
- ASK
- Mixed Lineage Kinase
- MAP4K
- MAPKAPK2
Cytoskeletal Signaling
- Akt
- Wnt/beta-catenin
- Bcr-Abl
- PKC
- FAK
- HSP (HSP90)
- Kinesin
- ROCK
- Microtubule Associated
- MPS1
- Dynamin
- PAK
- Integrin
- MLCK
- Gap-Junction
- Actin
- Cardiac Myosin
- PORCN
- TACC3
Cell Cycle
- CDK
- DNA/RNA Synthesis
- PD-1/PD-L1
- Ras
- Aurora Kinase
- HSP (HSP90)
- Kinesin
- Chk
- ROCK
- Microtubule Associated
- DHFR
- PLK
- APC
- Wee1
- MPS1
- DYRK
- Casein Kinase
- PERK
- TOPK
- Myc
- Serine/threonin kinase
- PAK
- Rho
- Nur77
- TACC3
- PP2A
- RUNX
- PFKFB
- LIM kinase
- Mad2
- Haspin Kinase
- Choline kinase
- AP-1
- BMI-1
- DOCK
- p21
- FOXM1
- eIF
TGF-beta/Smad
- TGF-beta/Smad
- Bcr-Abl
- PKC
- ROCK
DNA Damage/DNA Repair
- HDAC
- ATM/ATR
- PARP
- DNA/RNA Synthesis
- PPAR
- MDM2/MDMX
- Sirtuin
- Topoisomerase
- DNA-PK
- DHFR
- Telomerase
- High-mobility Group
- DNA alkylator
- MTH1
- Casein Kinase
- FENs
- OGG1
- Thymidylate Synthase
- G-quadruplex
- NUDIX
- RNR
- eIF
- SMN
- Nucleoside Analog/Antimetabolite
- LIM kinase
- RAD51
- CRISPR/Cas9
- BMI-1
- Pax
Stem Cells & Wnt
- GSK-3
- JAK
- STAT
- TGF-beta/Smad
- Wnt/beta-catenin
- ROCK
- Hedgehog/Smoothened
- PKA
- KLF
- OCT
- Casein Kinase
- ERK
- Stemness kinase
- SFRP
- Fascin
- PORCN
- Notch
- Secretase
Hippo
- MAP4K
- MST
- YAP
- LATS
- TEAD
Ubiquitin
- Proteasome
- DUB
- E2 conjugating
- E3 Ligase
- p97
- E1 Activating
- SUMO
Neuronal Signaling
- Calcium Channel
- Beta Amyloid
- 5-HT Receptor
- COX
- GluR
- Adrenergic Receptor
- AChR
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GABA Receptor
- P-gp
- P2 Receptor
- Cannabinoid Receptor
- OX Receptor
- CGRP Receptor
- MT Receptor
- MAO
- FAAH
- GlyT
- NMDAR
- CaMK
- BACE
- Trk receptor
- Adenosine Kinase
- BChE
- EAAT
- Neurokinin Receptor
- Notch
- Imidazoline Receptor
- Sigma Receptor
- NPY receptor
- Serotonin Transporter
- CCK receptor
- Neurotensin Receptor
- COMT
- Melanocortin Receptor
- Adenosine Deaminase
- TRP Channel
NF-κB
- HDAC
- NF-κB
- IκB/IKK
- NOD
- MALT
- Nrf2
- ROS
- Antioxidant
- AP-1
GPCR & G Protein
- Ras
- 5-HT Receptor
- CCR
- GluR
- Adrenergic Receptor
- AChR
- Histamine Receptor
- Dopamine Receptor
- Opioid Receptor
- GPR
- P2 Receptor
- Cannabinoid Receptor
- Endothelin Receptor
- S1P Receptor
- Hedgehog/Smoothened
- SGLT
- LPA Receptor
- OX Receptor
- CGRP Receptor
- MT Receptor
- PAFR
- PKA
- Glucagon Receptor
- LTR
- Adenosine Receptor
- Vasopressin Receptor
- cAMP
- CXCR
- TAAR
- CaSR
- Neurokinin Receptor
- GNRH Receptor
- PKG
- CRFR
- Angiotensin Receptor
- Bradykinin Receptor
- Imidazoline Receptor
- Bombesin Receptor
- RGS
- Neurotensin Receptor
- Sigma Receptor
- Melanocortin Receptor
- Taste Receptor
- PAR
- Parathyroid Hormone Receptor
- NPY receptor
- DOCK
- GPCR19
- AdipoR
- Guanylate Cyclase
- GHSR
- CCK receptor
- FPR
- GRK
- Leukotriene
- Prostaglandin Receptor
- PKD
- TSH Receptor
Endocrinology & Hormones
- Adrenergic Receptor
- 5-alpha Reductase
- Estrogen/progestogen Receptor
- Androgen Receptor
- RAAS
- Opioid Receptor
- Aromatase
- GPR
- Glucocorticoid Receptor
- SSTR
- GHSR
- CCK receptor
- PGES
- TSH Receptor
- GNRH Receptor
- PGDS
- Mineralocorticoid Receptor
- THR
- ACE
Transmembrane Transporters
- CD markers
- Calcium Channel
- Sodium Channel
- ATPase
- Chloride Channel
- Potassium Channel
- GluR
- AChR
- GABA Receptor
- P-gp
- Proton Pump
- CFTR
- P2 Receptor
- SGLT
- GLUT
- GlyT
- NMDAR
- OCT
- CRM1
- Mechanosensitive Channel
- OAT
- NKCC
- BCRP
- NCX
- OATP
- TRP Channel
- VRAC
- Aquaporin
- EAAT
- VDAC
- MTP
- VMAT
- GlyR
- MCT
- Amino acid transporter
Metabolism
- PPAR
- P450 (e.g. CYP17)
- HSP (HSP90)
- PDE
- Hydroxylase
- Factor Xa
- DHFR
- Aminopeptidase
- Dehydrogenase
- Procollagen C Proteinase
- Phospholipase (e.g. PLA)
- DPP
- Carbonic Anhydrase
- Phosphorylase
- Liver X Receptor
- FAAH
- Acyltransferase
- FXR
- Transferase
- Serine/threonin kinase
- CETP
- IDO/TDO
- GLUT
- phosphatase
- HMG-CoA Reductase
- Vitamin
- Lipoxygenase
- PKM
- Lipase
- FOX
- Fatty Acid Synthase
- NAMPT
- LDL
- Casein Kinase
- Decarboxylase
- Retinoid Receptor
- Thioredoxin
- OXPHOS
- Glutathione
- Acetyl-CoA carboxylase
- Adenosine Kinase
- Peroxidases
- SHIP
- PCSK9
- Mitochondrial Metabolism
- Mitochondrial pyruvate carrier
- PREP
- PGDS
- PP2A
- Neprilysin
- RUNX
- FTO
- AdipoR
- PAD
- SREBP
- SCD
- CPT
- LDH
- Carbohydrate Metabolism
- CAR
- AP-1
- PAI-1
- γGCS
- SSTR
- FAO
- FTase
- SOD
- ATP-citrate lyase
- 3-MST
- GTPCH
- SGK
- GOT
- Epoxide Hydrolase
- glucocerebrosidase
- FABP
- Serine hydrolase
- THR
- ACSS2
- ROR
- Catalase
- ACE
- Thioredoxin Reductase
- PDHK
- Glucosylceramide Synthase
- Xanthine Oxidase
- Mannosidase
- PGC-1α
- PARG
- Aldose Reductase
- CPSase
- Leukotriene
- Adenosine Deaminase
Proteases
- HDAC
- Proteasome
- Caspase
- Aminopeptidase
- HCV Protease
- DPP
- HIV Protease
- MMP
- Thrombin
- Acyltransferase
- Glutaminase
- Tyrosinase
- Serine Protease
- Cysteine Protease
- MALT
- Cathepsin B
- PGDS
- Neprilysin
- SGK
- GOT
- PREP
- 3C-Like Protease
- PCSK9
- PAD
- Secretase
Microbiology
- HCV Protease
- Integrase
- Reverse Transcriptase
- HIV Protease
- Anti-infection
- SARS-CoV
- RSV
- HPV
- HSV
- HCV
- HBV
- HIV
- Fungal
- CMV
- Neuraminidase
- Parasite
- Antiviral
- Thioredoxin Reductase
- Bacterial
- β-lactamase
- Antibiotics
- 3C-Like Protease
- Enterovirus
- COVID-19
- Influenza Virus
- Ribosomal Peptidyl Transferase
Others
- ADC Cytotoxin
- ADC Linker
- Drug-Linker Conjugates for ADC
- Antineoplastic and Immunosuppressive Antibiotics
- Selection Antibiotics for Transfected Cell
- Antibiotics for Mammalian Cell Culture
- Antibiotics for Plant Cell Culture
- Hydrotropic Agents
- Dyes
- PROTAC
- PROTAC Linker
- E3 ligase Ligand
- Target Protein Ligand
- Others
- Antibody-Drug Conjugate

Archives

Popular Post

ESKM, a novel therapeutic agent for sensitive and resistant PH+ leukemias

The mechanism of resistance to JAK2 inhibitor in myeloproliferative neoplasms patients

Effects of PARP inhibitors in BRCA gene-mutated ovarian cancer

DASATINIB; An inhibitor of Receptor Tyrosine Kinase

GP130/JAK/STAT3 signaling pathway induces multiple myeloma

NLR

The Effects of NLRP3 Inflammasome Inhibition by MCC950 on LPS-induced Pancreatic Adenocarcinoma Inflammation

467 views | Jun 10 2020

Alan Cheuk Keong Yaw et al. showed there was a dynamic interaction between inflammasome that regulated inflammasome-mediated inflammation in pancreatic adenocarcinoma cells. [Read the Full Post]

Rapamycin combined with MCC950 to treat multiple sclerosis in experimental autoimmune encephalomyelitis

0 views | Apr 01 2020

Xu L et al. provided theoretical support to the therapeutic evaluation of RAPA and MCC950 to make the mammalian targets of RAPA and NLRP3 the therapeutic targets of MS. [Read the Full Post]

Rapamycin Combined With MCC950 to Treat Multiple Sclerosis in Experimental Autoimmune Encephalomyelitis

803 views | Feb 18 2020

Ling Xu et al. provided theoretical support to the therapeutic evaluation of RAPA and MCC950 to make the mammalian targets of RAPA and NLRP3 the therapeutic targets of MS. [Read the Full Post]